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    33.
    发明专利
    未知

    公开(公告)号：DE58905246D1

    公开(公告)日：1993-09-16

    申请号：DE58905246

    申请日：1989-10-04

    Applicant: BASF AG

    Inventor： FRICKEL FRITZ-FRIEDER DR ,  KUEKENHOEHNER THOMAS DR ,  RENDENBACH-MUELLER BEATRICE DR ,  WEIFENBACH HARALD DR ,  TESCHENDORF HANS-JUERGEN DR

    IPC: A61K31/335 ,  A61K31/35 ,  A61K31/40 ,  A61K31/41 ,  A61K31/44 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/445 ,  A61K31/47 ,  A61P25/00 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D419/12

    Abstract: Heterocyclically substituted alkoxycoumarins of the formula in which R and R are, independently of one another, hydrogen, C1- to C5-alkyl, trifluoromethyl, phenyl, halogen or together are a C3- to C5-alkylene chain; furthermore R is C1- to C5-alkyl or halogen; n is an integer from 0 to 3; R is hydrogen or C1- to C4-alkyl and Het is one of the following heterocycles: with the following meanings for the symbols used: X is oxygen or sulphur; R is optionally C1-C4-alkoxy-substituted C1-C10-alkyl, 5-6-membered oxacycloalkyl, C3-C7-cycloalkyl, benzyl, an optionally halogen- or NO2-substituted phenyl radical, a pyridine ring, C1-C5-alkoxycarbonyl, perfluoro-C1-C2-alkyl; R is C1-C5-alkyl, C1-C5-alkoxy; R is C1-C5-alkyl, an optionally halogen-substituted benzyl radical, halogen; m is 0 to 2; R is C1-C5-alkyl, C3-C6-cycloalkyl, benzyl, phenyl; R is hydrogen, C1-C4-alkyl; R is C1-C5-alkyl, C3-C6-cycloalkyl; R is C1-C5-alkyl; R is hydrogen, C1-C5-alkyl, C3-C6-cycloalkyl; R is C1-C5-alkyl, halogen, p = 0 to 2; R is C1-C5-alkyl, q = 0 or 1; R , R are hydrogen, C1-C5-alkyl, benzyl; R is hydrogen, C1-C5-alkyl; R is C1-C5-alkyl with the proviso that R is not phenyl when X is oxygen, R is methyl and R to R are hydrogen, method for their preparation and medicaments prepared therefrom.

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