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公开(公告)号:BR112018000481B1
公开(公告)日:2022-01-11
申请号:BR112018000481
申请日:2016-07-08
Applicant: BASF SE , UNIV HEIDELBERG RUPRECHT KARLS
Inventor: REIN CHRISTIAN , STRAUTMANN JULIA , WEINGARTEN MELANIE , BREUER MICHAEL , HOFMANN PETER , PACIELLO ROCCO , SCHMIDT SEBASTIAN , RUEDENAUER STEFAN , SIEGEL WOLFGANG
IPC: C07C45/49 , C07C45/50 , C07C45/69 , C07C47/21 , C07D307/92
Abstract: a presente invenção refere-se a um processo para a hidroformilação regiosseletiva de hidrocarbonetos acíclicos poli-insaturados, que são 1,3-butadienos que, na posição 2, contêm um radical hidrocarboneto acíclico saturado ou monoinsaturado ou poli-insaturado. a presente invenção também se refere à produção de produtos secundários destes produtos de hidroformilação e especiamente de ambrox.
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公开(公告)号:AU2013349330C1
公开(公告)日:2019-11-14
申请号:AU2013349330
申请日:2013-11-13
Applicant: BASF SE
Inventor: ZELDER OSKAR , HOFF BIRGIT , SCHRODER HARTWIG , MOLT ANDREA , HARTMANN HOLGER , DITRICH KLAUS , BREUER MICHAEL , REINGRUBER RUDIGER , WEBER JAKOB
IPC: C12N15/11 , A01N37/00 , C07D307/77 , C12N15/63 , C12N15/67
Abstract: The invention pertains to the field of production of natural products and, in particular, in the field of production of cornexistin and hydroxycornexistin. It provides polynucleotides encoding polypeptides involved in the biosynthesis of cornexistin and hydroxycornexistin as well as vectors and recombinant microorganisms comprising such polynucleotides. Also provided are methods for the production of natural products, in particular methods for the production of cornexistin and hydroxycornexistin, using such polynucleotides and polpeptides encoded therein, as well as vectors and recombinant microorganisms comprising such polynucleotides and polypeptides.
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公开(公告)号:ES2718753T3
公开(公告)日:2019-07-04
申请号:ES15770541
申请日:2015-09-28
Applicant: BASF SE
Inventor: BREUER MICHAEL , PELZER RALF
IPC: C07D311/92 , C12P17/06
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公开(公告)号:CA2735769C
公开(公告)日:2018-10-09
申请号:CA2735769
申请日:2009-09-15
Applicant: BASF SE
Inventor: BREUER MICHAEL , PLETSCH ANDREAS , HAUER BERNHARD , SIEGEL WOLFGANG
Abstract: The present invention relates to a multi-stage process for producing substituted, optically active alcohols, comprising an enzyme-catalyzed synthesis step, in particular a synthesis step which is catalyzed by an alcohol dehydrogenase. The inventive method is particularly suitable for producing phenylephrine, i.e. 3-[(1R)-1-hydroxy-2-methylamino-ethyl]-phenol.
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公开(公告)号:CA2978131A1
公开(公告)日:2016-09-29
申请号:CA2978131
申请日:2016-02-19
Applicant: BASF SE
Inventor: NAVICKAS VAIDOTAS , BREUER MICHAEL , PUHL MICHAEL , WEINGARTEN MELANIE , BALDENIUS KAI-UWE , SIEGEL WOLFGANG
Abstract: The invention relates to biocatalytic methods, including purely enzymatic, mixed enzymatic-fermentative and purely fermentative methods, for the direct single-step conversion of L-fucitol into L-fucose, in order to easily obtain L-fucose at high amounts and levels of purity. The invention also relates to suitable recombinant microorganisms and fungi, and to the use of same in said method for the single-step conversion of L-fucose.
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公开(公告)号:MX2015006385A
公开(公告)日:2015-12-08
申请号:MX2015006385
申请日:2013-11-13
Applicant: BASF SE
Inventor: SCHRÖDER HARTWIG , HOFF BIRGIT , ZELDER OSKAR , MOLT ANDREA , DITRICH KLAUS , BREUER MICHAEL , HARTMANN HOLGER , REINGRUBER RÜDIGER , WEBER JAKOB
IPC: C12N15/11 , A01N37/00 , C07D307/77 , C12N15/63 , C12N15/67
Abstract: La invención pertenece al campo de producción de productos naturales y, en particular, en el campo de la producción de cornexistina e hidroxicornexistina. Proporciona polinucleóticos que codifican polipéptidos implicados en la biosíntesis de cornexistiria e hidroxicornexistina, así como vectores y microorganismos recombinantes que comprenden tales polinucleótidos. También se proporcionan métodos para la producción de productos naturales, en particular métodos para la producción de cornexistina e hidroxicornexistina, usando tales polinucleótidos y polipéptidos codificados allí, así como vectores y microorganismos recombinantes que comprenden tales polinucleótidos y polipéptidos.
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公开(公告)号:CA2880845A1
公开(公告)日:2014-02-27
申请号:CA2880845
申请日:2013-08-13
Applicant: BASF SE
Inventor: NAESBY MICHAEL , FOLLY CHRISTOPHE , NIELSEN CURT AIME FRIIS , HATSCH ANAELLE , SCHWAB MARKUS , ZELDER OSKAR , HAEFNER STEFAN , SCHRODER HARTWIG , HOFF BIRGIT , MOLT ANDREA , DITRICH KLAUS , BREUER MICHAEL , HARTMANN HOLGER , KORBER KARSTEN
IPC: C12N1/21 , A61K31/48 , C07K14/195 , C07K14/37 , C07K16/00 , C12N1/15 , C12N1/16 , C12N15/31 , C12N15/52 , C12N15/80 , C12N15/81 , C12P1/00 , C12P17/10
Abstract: Microorganisms and processes for the recombinant manufacture of clavine-type alkaloids such as cycloclavine, festuclavine, agroclavine, chanoclavine and chanoclavine aldehyde, as well as polypeptides, polynucleotides and vectors comprising such polynucleotides which can be applied in a method for the manufacture of clavine-type alkaloids are provided.
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公开(公告)号:MX2011012757A
公开(公告)日:2011-12-16
申请号:MX2011012757
申请日:2010-06-02
Applicant: BASF SE
Inventor: HAUER BERNHARD , BREUER MICHAEL , HOERSTER ANDREA
Abstract: La invención se refiere a un método para la producción biocatalítica de ambroxán por medio de un polipéptido que tiene la actividad de una homofarnesol-ambroxán ciclasa y que representa una clase novedosa de enzimas.
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公开(公告)号:SI1969133T1
公开(公告)日:2011-01-31
申请号:SI200630832
申请日:2006-12-13
Applicant: BASF SE
Inventor: BREUER MICHAEL
IPC: C12P17/00 , C07D333/00
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公开(公告)号:PT1929001E
公开(公告)日:2010-05-25
申请号:PT06806768
申请日:2006-09-14
Applicant: BASF SE
Inventor: FRIEDRICH THOMAS , BREUER MICHAEL , KESSELER MARIA
IPC: C12N9/04
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