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公开(公告)号：DE69333958T2
公开(公告)日：2006-08-03
申请号：DE69333958
申请日：1993-07-07
Applicant: FUSO PHARMACEUTICAL IND , OHNO TSUNEYA
Inventor： OHNO TSUNEYA , MATSUHISA AKIO , UEHARA HIROTSUGU , EDA SOJI
IPC: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566
Abstract: A probe for diagnosing infectious diseases in which the probe comprises the base sequence set out in SEQ. ID. No. 7 and specifically reacts with DNA of Staphylococcus epidermidis.
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公开(公告)号：AT321881T
公开(公告)日：2006-04-15
申请号：AT97932996
申请日：1997-07-24
Applicant: FUSO PHARMACEUTICAL IND
Inventor： KESHI HIROYUKI , EDA SOJI , UEHARA HIROTSUGU , NISHIDA KEIGO , MATSUHISA AKIO
Abstract: Probes for specifically detecting and identifying Helicobacter pylori which serves as an inflammatory bacterium in digestive diseases. These probes contain a fragment formed by completely digesting a DNA carried by H. pylori with a restriction enzyme HindIII. The information of the base sequences of these probes are useful as a structural indication of primers to be used in the construction of probes specific to H. pylori by PCR or as standard sequences suitable for the comparison with genomic DNAs contained in clinical specimens.
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公开(公告)号：DE69333808D1
公开(公告)日：2005-06-16
申请号：DE69333808
申请日：1993-10-25
Applicant: FUSO PHARMACEUTICAL IND , OHNO TSUNEYA
Inventor： OHNO TSUNEYA , HIROTSU TAKUO , KESHI HIROYUKI , MATSUHISA AKIO
Abstract: The invention provides a probe useful for rapidly detecting and identifying fungi causative of infectious diseases by digesting completely a DNA extracted from a fungus Candidat albicans with EcoRI, inserting the same into an appropriate cloning vector, and picking up a probe containing DNA fragments unique to each fungus. The invention also provides a standard sequence suitable for making reference to a genomic DNA contained in a clinical specimen by elucidating the base sequence of the probe thus picked up.
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公开(公告)号：DK0670373T3
公开(公告)日：2005-06-06
申请号：DK93923652
申请日：1993-10-25
Applicant: FUSO PHARMACEUTICAL IND , OHNO TSUNEYA
Inventor： OHNO TSUNEYA , HIROTSU TAKUO , KESHI HIROYUKI , MATSUHISA AKIO
IPC: C12Q1/68
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公开(公告)号：AT295425T
公开(公告)日：2005-05-15
申请号：AT93923652
申请日：1993-10-25
Applicant: FUSO PHARMACEUTICAL IND , OHNO TSUNEYA
Inventor： OHNO TSUNEYA , HIROTSU TAKUO , KESHI HIROYUKI , MATSUHISA AKIO
Abstract: The invention provides a probe useful for rapidly detecting and identifying fungi causative of infectious diseases by digesting completely a DNA extracted from a fungus Candidat albicans with EcoRI, inserting the same into an appropriate cloning vector, and picking up a probe containing DNA fragments unique to each fungus. The invention also provides a standard sequence suitable for making reference to a genomic DNA contained in a clinical specimen by elucidating the base sequence of the probe thus picked up.
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Patent Agency Ranking
公开(公告)号：CA2284858C
公开(公告)日：2004-07-20
申请号：CA2284858
申请日：1998-03-23
Applicant: FUSO PHARMACEUTICAL IND
Inventor： ABE KANAKO , MATSUHISA AKIO , UEYAMA HIROSHI , KESHI HIROYUKI
Abstract: The DNA from the bacteria Klebsiella pneumoniae is extracted, then completely digested with restriction enzyme HindIII, followed by cloning int o a suitable vector to select a probe comprising DNA which is essentially contained in Klebsiella pneumoniae , then the sequence of the probe is elucidated.
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公开(公告)号：DE69333008D1
公开(公告)日：2003-07-03
申请号：DE69333008
申请日：1993-07-07
Applicant: FUSO PHARMACEUTICAL IND , OHNO TSUNEYA
Inventor： OHNO TSUNEYA , MATSUHISA AKIO , UEHARA HIROTSUGU , EDA SOJI
IPC: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566
Abstract: A probe for diagnosing infectious diseases in which the probe comprises the base sequence set out in SEQ. ID. No. 7 and specifically reacts with DNA of Staphylococcus epidermidis.
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公开(公告)号：DK0785277T3
公开(公告)日：2003-06-10
申请号：DK95933618
申请日：1995-10-02
Applicant: FUSO PHARMACEUTICAL IND
Inventor： KESHI HIROYUKI , EDA SOJI , UEHARA HIROTSUGU , UEYAMA HIROSHI , MATSUHISA AKIO
Abstract: A probe derived from phlogogenic bacteria of pneumonia, containing fragments of DNA which streptococcus pneumoniae essentially possesses, and useful for detecting and identifying causative bacteria of pneumonia is obtained by completely digesting the DNA with a restriction endonuclease PstI, followed by cloning into a suitable vector.
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公开(公告)号：CA2447775A1
公开(公告)日：2002-12-19
申请号：CA2447775
申请日：2002-05-27
Applicant: FUSO PHARMACEUTICAL IND
Inventor： MATSUHISA AKIO , ABE KANAKO , KESHI HIROYUKI , SUGIMOTO NORIHIKO , ARAKI HIROMASA , YAMAMOTO SEIJI , OHNO TSUNEYA , UEYAMA HIROSHI , IWAMI TAKAHISA , UEHARA HIROTSUGU , EDA SOJI
Abstract: Phagocytes having taken a foreign microorganism which are prepared by bringi ng phagocytes into contact with the microorganism and then isolating the phagocytes; a process for producing the same; and a method and a kit with th e use of the same. An experimental model whereby the phagocytosis function of phagocytes can be evaluated in vitro.
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公开(公告)号：DE69331443T2
公开(公告)日：2002-09-05
申请号：DE69331443
申请日：1993-08-10
Applicant: FUSO PHARMACEUTICAL IND
Inventor： MATSUHISA AKIO , SHIBA KIYOTAKA , MIKAWA YOSHIKAZU , KISHI YUICHIRO
IPC: C12Q1/68 , C12Q1/6813 , C12Q1/6816 , G01N27/447 , G01N33/50 , G01N33/58 , C12Q1/28 , C12Q1/42
Abstract: A method of detecting a nucleic acid which comprises bringing a solid carrier suspected to carry or contain a nucleic acid into contact with a polyamine containing, bound thereto, a label capable of generating a detectable signal or a precursor thereof to thereby form a complex between a nucleic acid, if any, and the polyamine, removing the polyamine which has not formed any complex before or after the conversion of the precursor, if used, into the label, and detecting the label.
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