公开(公告)号：NO784366A

公开(公告)日：1979-06-26

申请号：NO784366

申请日：1978-12-22

Applicant: HOECHST AG

Inventor： BLUMBACH JUERGEN ,  DUERCKHEIMER WALTER ,  SCHRINNER ELMAR

IPC: C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/46 ,  C07D501/34 ,  C07D

CPC classification number: C07D277/587 ,  C07D277/46

公开(公告)号：FI783960A

公开(公告)日：1979-06-25

申请号：FI783960

申请日：1978-12-21

Applicant: HOECHST AG

Inventor： BLUMBACH JUERGEN ,  DUERCKHEIMER WALTER ,  SCHRINNER ELMAR

IPC: C07D501/06 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  C07D277/20 ,  C07D277/46 ,  C07D501/34 ,  C07D

Abstract: Cephalosporin derivatives of the formula I processes for their manufacture and their use for combating bacterial infections.

公开(公告)号：FI780966A

公开(公告)日：1978-10-03

申请号：FI780966

申请日：1978-03-30

Applicant: HOECHST AG

Inventor： DUERCKHEIMER WALTER ,  BORMANN DIETER ,  EHLERS EBERHARD ,  SCHRINNER ELMAR ,  HEYMES RENE

IPC: A61K31/397 ,  A61K31/435 ,  A61K31/505 ,  A61K31/535 ,  A61K31/545 ,  A61K31/546 ,  A61P31/04 ,  B25J15/08 ,  C07D205/08 ,  C07D277/20 ,  C07D277/40 ,  C07D277/42 ,  C07D277/50 ,  C07D463/00 ,  C07D471/04 ,  C07D487/04 ,  C07D498/04 ,  C07D501/20 ,  C07D501/24 ,  C07D501/36 ,  C07D505/00 ,  C07D519/06 ,  C07F9/6561 ,  C07D

Abstract: Cephem derivatives of the general formula in which the R2O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.

公开(公告)号：ZA757771B

公开(公告)日：1976-11-24

申请号：ZA757771

申请日：1975-12-12

Applicant: HOECHST AG

Inventor： SCHORR MANFRED ,  MANFRED SCHORR ,  SCHRINNER ELMAR ,  ELMAR SCHRINNER ,  SCHMITT WILFRIED ,  WILFRIED SCHMITT

IPC: C07D499/66 ,  C07D499/00 ,  C07D499/64 ,  C07D499/68 ,  C07D499/70 ,  C07D

Abstract: Acylaminopenicillanic acids of the general formula in which R1, R2 and R3 represent hydrogen or lower alkyl which may be substituted, and in which the radicals R1 and R2 or R2 and R3 may form together an alkylene radical which may be substituted, R4 and R5 represent hydrogen or lower alkyl, R6 represents phenyl which may be substituted, a monocyclic aromatic heterocycle which may be substituted, or dihydrophenyl, A represents a benzene or thiophene ring which may be substituted, and X represents oxygen or a single bond, a process for preparing them and pharmaceutical compositions active against bacterial infections containing these compounds.

公开(公告)号：AU8007475A

公开(公告)日：1976-10-14

申请号：AU8007475

申请日：1975-04-11

Applicant: HOECHST AG

Inventor： MARTIN WOLFGANG ,  DURCKHEIMER WALTER ,  SCHRINNER ELMAR

IPC: C07D319/06 ,  C07C67/00 ,  C07C231/00 ,  C07C231/08 ,  C07C231/12 ,  C07C237/26 ,  C07D211/34 ,  C07D211/62 ,  C07D295/13 ,  C07C103/86 ,  C07D13/02 ,  C07D15/04 ,  A61K21/00

Abstract: Antibacterially-active tetracyclines, substituted at the amide group, and physiologically-tolerable salts thereof, said tetracyclines having the formula METHODS OF MAKING THE SAME; PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME.

公开(公告)号：PT98185A

公开(公告)日：1994-02-28

申请号：PT9818591

申请日：1991-07-02

Applicant: HOECHST AG

Inventor： SCHRINNER ELMAR ,  WINKLER IRVIN ,  DIRINGER HEINO ,  EHLERS BERNHARDT

IPC: A61K31/715 ,  A61K31/70 ,  A61P31/12 ,  A61K31/725

Abstract: Sulphated polysaccharides and derivatives thereof are suitable for the long-term prophylaxis of diseases caused by viruses or by unconventional viruses.

公开(公告)号：DK163244C

公开(公告)日：1992-06-29

申请号：DK162878

申请日：1978-04-14

Applicant: HOECHST AG

Inventor： DUERCKHEIMER WALTER ,  EHLERS EBERHARD ,  SELIGER HUBERT ,  SCHRINNER ELMAR

IPC: A61K20060101 ,  A61K31/545 ,  A61K31/546 ,  A61K31/675 ,  A61K31/695 ,  A61P31/04 ,  B23K1/18 ,  B23Q5/033 ,  C07D20060101 ,  C07D277/20 ,  C07D277/40 ,  C07D501/00 ,  C07D501/20 ,  C07D501/24 ,  C07D501/34 ,  C07D501/36 ,  C07D501/46 ,  C07D501/59 ,  C07D501/60 ,  C07D519/06

Abstract: What are disclosed are cephem compounds of the formula in which R1 denotes hydrogen, an optionally substituted alkyl, acyl, arylsulfonyl or alkylsulfonyl group or an amino-protective group which is known from peptide chemistry, R2 denotes hydrogen or an optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, aralkyl, acyl, aryl, arylsulfonyl, alkylsulfonyl or heterocyclic group, R3 denotes hydrogen, an ester group or a cation, R4 denotes hydrogen, a lower alkoxy group or a group which can be converted to this, X denotes a SO group in the R or S configuration or a SO2 group and A denotes hydrogen, an optionally substituted alkoxy or alkenyloxy group, halogen or a group -CH2Y, in which Y represents hydrogen, halogen or the radical of a nucleophilic compound, and in which the R2O group is in the syn-position, which compounds are valuable chemotherapeutic agents having a very powerful antimicrobial action against Gram-positive and Gram-negative bacteria and an unexpectedly good action against penicillinase-forming Staphilococci.

公开(公告)号：CA1294217C

公开(公告)日：1992-01-14

申请号：CA538710

申请日：1987-06-03

Applicant: HOECHST AG

Inventor： LIMBERT MICHAEL ,  SCHRINNER ELMAR ,  SEIBERT GERHARD

IPC: A61K31/545 ,  A61P31/04

Abstract: of the disclosure A pharmaceutical formulation having a synergistic antibacterial activity and comprising a) a cephalosporin derivative or a physiologically acceptable salt or ester thereof and b) a penem antibiotic of the basic structure (B) (B) or a physiologically acceptable salt or ester thereof, a process for preparing such a formulation and its use for the treatment of bacterial infections.

公开(公告)号：AU7947091A

公开(公告)日：1992-01-09

申请号：AU7947091

申请日：1991-07-02

Applicant: HOECHST AG

Inventor： DIRINGER HEINO ,  EHLERS BERNHARDT ,  SCHRINNER ELMAR ,  WINKLER IRVIN

IPC: A61K31/715 ,  A61K31/70 ,  A61P31/12 ,  A61K31/725

Abstract: Sulphated polysaccharides and derivatives thereof are suitable for the long-term prophylaxis of diseases caused by viruses or by unconventional viruses.

公开(公告)号：HUT52957A

公开(公告)日：1990-09-28

申请号：HU404888

申请日：1988-07-29

Applicant: HOECHST AG

Inventor： SCHRINNER ELMAR ,  WINKLER IRVIN ,  MEICHSNER CHRISTOPH ,  HELSBERG MATTHIAS

IPC: C07D473/06 ,  A61K20060101 ,  A61K31/52 ,  A61K31/70 ,  A61K31/715 ,  A61P31/12 ,  C07D20060101 ,  C07D473/04 ,  C08B20060101 ,  C08B37/00

Abstract: The preparation contains or consists of… a) at least one sulphated polysaccharide and… b) at least one xanthine derivative. The preparation is suitable for the control and prophylaxis of viral diseases, especially those caused by retroviruses.