公开(公告)号：DK149590C

公开(公告)日：1987-02-09

申请号：DK532679

申请日：1979-12-14

Applicant: BASF AG

Inventor： THYES MARCO ,  GRIES JOSEF ,  LEHMANN HANS DIETER ,  KUNZE JOHANNES ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/395 ,  A61K31/502 ,  A61P7/02 ,  A61P9/12 ,  C07C62/38 ,  C07C205/56 ,  C07D231/54 ,  C07D237/26 ,  C07D403/10

Abstract: 2-Aryl-3,4-diaza-bicyclo-[4.1.0]hept-2-en-5-ones, substituted in the phenyl ring, of the general formula their preparation, and therapeutic agents, containing these compounds, which may be used for the treatment of hypertension or of thrombo-embolic disorders.

公开(公告)号：HU187327B

公开(公告)日：1985-12-28

申请号：HU73881

申请日：1981-03-23

Applicant: BASF AG

Inventor： MAY HANS-JOACHIM ,  LENKE DIETER ,  GRIES JOSEF ,  TESCHENDORF HANS-JUERGEN ,  WORSTMANN WOLFGANG

IPC: C07D409/06 ,  A61K31/33 ,  A61K31/415 ,  A61K31/465 ,  A61K31/47 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P43/00 ,  C07D233/54 ,  C07D233/64 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D413/06 ,  C07D417/06 ,  C07D407/06

Abstract: 1-Aroyl-2-phenylamino-2-imidazolines of the general formula where R1 and R2 are identical or different and each is chlorine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano, R3 has the meanings given for R1 and R2 or is hydrogen and Ar is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds. The compounds have, inter alia, a blood pressure-reducing action.

公开(公告)号：CS238621B2

公开(公告)日：1985-12-16

申请号：CS245882

申请日：1982-04-06

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMAN HANS D ,  FRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS J ,  DENGEL FERDINAND ,  FRANK WOLFRAM ,  KURBJUWEIT HANS-GEORG ,  MUELLER CLAUS D

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/66

公开(公告)号：CA1194024A

公开(公告)日：1985-09-24

申请号：CA423169

申请日：1983-03-09

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  GRIES JOSEF ,  LEHMANN HANS D ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/26

Abstract: 6-aryl-4,5-dihydro-3(2H)-pyridazinones of the formula (I), where R is hydrogen, R1 is hydrogen or C1-C3-alkyl, or R and R1 together are methylene, R2 and R3 are identical or different and are each hydrogen or C1-C6-alkyl, and A is hydroxyl, C1-C6-alkoxy, C2-C7-acyloxy, a C2-C7-carbamic acid ester group, C1-C6-alkylsul-fonyloxy, C1-C6-alkylmercapto, carboxyl, C2-C7-alkoxy-carbonyl or nitrile, and their preparation are described. The substances are suitable for the treatment of high blood pressure or thrombo-embolic disorders.

公开(公告)号：ZA849380B

公开(公告)日：1985-08-28

申请号：ZA849380

申请日：1984-12-03

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  SPIEGLER WOLFGANG ,  SIEGEL HARDO ,  MUELLER CLAUS D ,  PHILIPSBORN GERDA VON ,  LENKE DIETER ,  GRIES JOSEF

IPC: A61K31/34 ,  A61K31/341 ,  A61K31/38 ,  A61K31/381 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/495 ,  A61P9/06 ,  C07D207/32 ,  C07D207/333 ,  C07D213/50 ,  C07D231/12 ,  C07D307/46 ,  C07D333/22 ,  C07D409/12 ,  C07D ,  A61K

公开(公告)号：NO844778A

公开(公告)日：1985-06-03

申请号：NO844778

申请日：1984-11-30

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  SPIEGLER WOLFGANG ,  SIEGEL HARDO ,  MUELLER CLAUS D ,  PHILIPSBORN GERDA VON ,  LENKE DIETER ,  GRIES JOSEF

IPC: A61K31/34 ,  A61K31/341 ,  A61K31/38 ,  A61K31/381 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/495 ,  A61P9/06 ,  C07D207/32 ,  C07D207/333 ,  C07D213/50 ,  C07D231/12 ,  C07D307/46 ,  C07D333/22 ,  C07D409/12 ,  C07D

CPC classification number: C07D207/333 ,  C07D213/50 ,  C07D231/12 ,  C07D307/46 ,  C07D333/22 ,  C07D409/12

公开(公告)号：HU186058B

公开(公告)日：1985-05-28

申请号：HU110982

申请日：1982-04-09

Applicant: BASF AG

Inventor： EHRMANN OSKAR ,  RASCHACK MANFRED ,  GRIES JOSEF ,  KRETZSCHMAR ROLF ,  LEHMANN HANS D ,  GRIEDRICH LUDWIG ,  WUPPERMANN DIRK ,  ZIMMERMANN FRANK ,  SEITZ WERNER ,  TREIBER HANS J ,  DENGEL FERDINAD ,  FRANK WOLFRAM ,  KURBJUWET HANS-GEORG ,  MUELLER CLAUS

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18 ,  C07C121/60 ,  C07C121/75

公开(公告)号：CS236500B2

公开(公告)日：1985-05-15

申请号：CS712783

申请日：1983-09-29

Applicant: BASF AG

Inventor： FRANKE ALBRECHT ,  MUELLER JOSEF ,  LIETZ HELMUT ,  WIERSDORF WALTER-WIELANT ,  HEGE HANS-GUENTHER ,  MUELLER CLAUS D ,  GRIES JOSEF ,  LENKE DIETER ,  VON PHILIPSBORN GERDA ,  RASCHACK MANFRED

IPC: A61K31/135 ,  A61K31/395 ,  C07D295/08 ,  C07D295/10 ,  C07C97/10 ,  C07C93/06 ,  C07D341/12

公开(公告)号：NO840213L

公开(公告)日：1984-07-23

申请号：NO840213

申请日：1984-01-20

Applicant: BASF AG

Inventor： ROSSY PHILLIP A ,  THYES MARCO ,  FRANKE ALBRECHT ,  KOENIG HORST ,  LEHMANN HANS DIETER ,  GRIES JOSEF ,  FRIEDRICH LUDWIG ,  LENKE DIETER

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00 ,  C07D

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：HU182454B

公开(公告)日：1984-01-30

申请号：HUBA003905

申请日：1979-12-14

Applicant: BASF AG

Inventor： THYES MARCO ,  GRIES JOSEF ,  LEHMANN HANS D ,  LENKE DIETER ,  KUNZE JOHANNES

IPC: A61K31/395 ,  A61K31/502 ,  A61K31/50 ,  A61P7/02 ,  A61P9/12 ,  C07C62/38 ,  C07C205/56 ,  C07D231/54 ,  C07D237/26 ,  C07D403/10

Abstract: 2-Aryl-3,4-diaza-bicyclo-[4.1.0]hept-2-en-5-ones, substituted in the phenyl ring, of the general formula their preparation, and therapeutic agents, containing these compounds, which may be used for the treatment of hypertension or of thrombo-embolic disorders.