公开(公告)号：DE3362130D1

公开(公告)日：1986-03-27

申请号：DE3362130

申请日：1983-11-11

Applicant: BASF AG

Inventor： TREIBER HANS JOERG DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST PROF DR ,  TESCHENDORF HANS-JUERGEN DR ,  TRAUT MARTIN DR

IPC: A61K31/55 ,  A61P25/24 ,  A61P25/26 ,  C07D267/08 ,  C07D267/10

公开(公告)号：DE3361181D1

公开(公告)日：1985-12-12

申请号：DE3361181

申请日：1983-11-17

Applicant: BASF AG

Inventor： SEITZ WERNER DR ,  TESCHENDORF HANS-JUERGEN DR ,  MICHEL ALFRED DR ,  TRAUT MARTIN DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST PROF DR

IPC: C07C225/18 ,  A61K31/135 ,  A61K31/205 ,  A61K31/395 ,  A61P25/24 ,  A61P25/26 ,  C07D207/08 ,  C07D211/32 ,  C07D295/10 ,  C07D295/116 ,  C07D295/12 ,  C07D295/145 ,  C07C97/10

Abstract: 1-Oxo-2-phenyl-2-(2-alkylaminoethyl)-1,2,3,4-tetrahydronaphthalenes of the formula I I where R1 and R2 are identical or different and are each hydrogen, halogen, trifluoromethyl, C1-C4-alkyl or C1-C4-alkoxy, R3 is C1-C6-alkyl and R4 is hydrogen, C1-C6-alkyl or benzyl, or R3 and R4 together may furthermore be a C2-C5-alkylene chain, and their salts with physiologically tolerated acids, and their preparation, are described. The novel compounds are useful active compounds for treating disorders.

公开(公告)号：DE3172852D1

公开(公告)日：1985-12-12

申请号：DE3172852

申请日：1981-12-23

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  STEINER GERD DR ,  THIEME PETER C DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：GR75787B

公开(公告)日：1984-08-02

申请号：GR810165898

申请日：1981-08-31

Applicant: BASF AG

Inventor： STEINER GERD DR ,  TESCHENDORF HANS-JUERGEN DR ,  KREISKOTT HORST DR ,  HOFMANN HANS PETER DR

IPC: B01D53/86 ,  B01J23/06 ,  C01B3/54

公开(公告)号：GR73857B

公开(公告)日：1984-05-08

申请号：GR810164200

申请日：1981-02-20

Applicant: BASF AG

Inventor： MAY HANS-JOACHIM DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR ,  TESCHENDORF HANS-JUERGEN DR ,  WORSTMANN WOLFGANG DR

IPC: C07D409/06 ,  A61K31/33 ,  A61K31/415 ,  A61K31/465 ,  A61K31/47 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P43/00 ,  C07D233/54 ,  C07D233/64 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D413/06 ,  C07D417/06

Abstract: 1-Aroyl-2-phenylamino-2-imidazolines of the general formula where R1 and R2 are identical or different and each is chlorine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano, R3 has the meanings given for R1 and R2 or is hydrogen and Ar is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds. The compounds have, inter alia, a blood pressure-reducing action.

公开(公告)号：DE3011327A1

公开(公告)日：1981-10-01

申请号：DE3011327

申请日：1980-03-24

Applicant: BASF AG

Inventor： MAY HANS-JOACHIM DIPL CHEM DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR ,  TESCHENDORF HANS-JUERGEN DR ,  WORSTMANN WOLFGANG DR

IPC: C07D409/06 ,  A61K31/33 ,  A61K31/415 ,  A61K31/465 ,  A61K31/47 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12 ,  A61P43/00 ,  C07D233/54 ,  C07D233/64 ,  C07D401/06 ,  C07D403/06 ,  C07D405/06 ,  C07D413/06 ,  C07D417/06 ,  C07D233/50 ,  C07D401/12 ,  C07D405/12 ,  C07D407/12 ,  C07D409/12 ,  A61K31/435 ,  A61K31/42 ,  A61K31/425

Abstract: 1-Aroyl-2-phenylamino-2-imidazolines of the general formula where R1 and R2 are identical or different and each is chlorine, bromine, fluorine, methyl, ethyl, methoxy, trifluoromethyl or cyano, R3 has the meanings given for R1 and R2 or is hydrogen and Ar is an unsubstituted or substituted monocyclic or bicyclic heteroaromatic radical containing 1, 2 or 3 nitrogen and/or oxygen and/or sulfur atoms, their salts with physiologically tolerated acids, their preparation, and drugs containing these compounds. The compounds have, inter alia, a blood pressure-reducing action.