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    Method for the production of directly compressible ibuprofen formulations
    63.
    发明专利
    Method for the production of directly compressible ibuprofen formulations 未知

    公开(公告)号：AU2006301307C1

    公开(公告)日：2012-05-24

    申请号：AU2006301307

    申请日：2006-10-05

    Applicant: BASF SE

    Inventor： MEYER-BOHM KATHRIN ,  KOLTER KARL ,  QUADIR ANISUL

    IPC: C07C57/30 ,  A61K9/16 ,  A61K9/20

    Abstract: Disclosed is a directly compressible ibuprofen formulation containing a) 50 to 99 percent by weight of crystalline ibuprofen, b) 1 to 15 percent by weight of a highly dispersible adjuvant having a minimum surface of 100 m/g, and c) 0 to 40 percent by weight of other adjuvants provided that the total quantity of components a) to c) amounts to 100 percent by weight, at least 50 percent of the surface of the ibuprofen crystals being coated with the highly dispersible adjuvant.

    65.
    发明专利
    未知

    公开(公告)号：AT535234T

    公开(公告)日：2011-12-15

    申请号：AT07857369

    申请日：2007-12-11

    Applicant: BASF SE

    Inventor： KOLTER KARL ,  MASCHKE ANGELIKA ,  DIETZEN FRANZ-JOSEF ,  SCHMELLER THORSTEN

    IPC: A61K9/28 ,  A61K9/14

    Abstract: Solid particulate film-coating compositions consisting of a) 40-90% by weight, preferably 40 to 70% by weight, of a polyvinyl alcohol-polyether graft copolymer (component A), b) 10 to 60% by weight, preferably 20 to 45% by weight, of a chromatic or achromatic colorant (component B) c) 0 to 30% by weight of further conventional auxiliaries (component C) where the amount of components A to C adds up to 100% by weight, which are obtained by extrusion of a melt of components A) to C) and subsequent shaping.

    67.
    发明专利
    未知

    公开(公告)号：AT420629T

    公开(公告)日：2009-01-15

    申请号：AT03742450

    申请日：2003-02-04

    Applicant: BASF SE

    Inventor： KOLTER KARL ,  ANGEL MAXIMILIAN

    IPC: A61K9/28

    Abstract: Rapidly dissolving film coating agent (I) comprises: (A) 10-90 wt.% polyvinyl alcohol polyether graft copolymer; (B) 5-80 wt. % at least one other component containing at least one functional group selected from hydroxy, amide and ester functions, and (C) 0-70 wt.% further conventional coating components. Independent claims are also included for: (1) production of coated substrates which comprises stirring (I) with water, applying the mixture to a substrate using a spraying apparatus and drying the obtained coating by supply of heated air, and (2) solid substrates film coated with (I).

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