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公开(公告)号：WO2007037961A1
公开(公告)日：2007-04-05
申请号：PCT/US2006/035278
申请日：2006-09-12
Applicant: COLGATE-PALMOLIVE COMPANY , CHOPRA, Suman, K. , ZAIDEL, Lynette , PRENCIPE, Michael
Inventor： CHOPRA, Suman, K. , ZAIDEL, Lynette , PRENCIPE, Michael
IPC: A61Q11/00 , A61K8/22 , A61K8/88 , A61K8/81 , A61K8/86 , A61K8/25 , A61K8/89 , A61K8/73 , A61K8/46 , A61K8/20
CPC classification number: A61K8/22 , A61K8/20 , A61K8/25 , A61K8/463 , A61K8/737 , A61K8/8152 , A61K8/8176 , A61K8/86 , A61K8/88 , A61K8/89 , A61Q11/00
Abstract: A single phase whitening dentifrice that includes (i) a whitening agent selected from the group consisting of hydrogen peroxide, a bound peroxide and a solid peroxide (ii) an abrasive and (iii) a substantially anhydrous orally acceptable carrier, for example, polyethylene glycol. The bound peroxide may be hydrogen peroxide and a polymer and/or any peroxide compound and a porous cross-linked polymer, such as polymers of polyvinyl pyrrolidone, polyacrylates, a polymethacrylates, and a polyitaconates. The solid peroxide may be sodium perborate or urea peroxide. The invention also provides methods of whitening the tooth surfaces by contacting the surface with the composition.
Abstract translation: 一种单相增白洁齿剂，其包括（i）选自过氧化氢，结合过氧化物和固体过氧化物的增白剂（ii）研磨剂和（iii）基本上无水的可口服可接受的载体，例如聚乙二醇 。 结合过氧化物可以是过氧化氢和聚合物和/或任何过氧化物化合物和多孔交联聚合物，例如聚乙烯吡咯烷酮聚合物，聚丙烯酸酯，聚甲基丙烯酸酯和多赖氨酸盐。 固体过氧化物可以是过硼酸钠或过氧化脲。 本发明还提供了通过使表面与组合物接触来使牙齿表面变白的方法。
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公开(公告)号：WO2007011552A2
公开(公告)日：2007-01-25
申请号：PCT/US2006/026512
申请日：2006-07-10
Applicant: COLGATE-PALMOLIVE COMPANY , MILLER, Jeffrey , BOYD, Thomas, J. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael , MORGAN, Andre
Inventor： MILLER, Jeffrey , BOYD, Thomas, J. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael , MORGAN, Andre
Abstract: An oral composition is provided covering one or more cationic active ingredients and a cationic-compatible inorganic particulate having a porous surface that is substantially inert to the cationic active ingredient. The oral composition also has a cationic-compatible surfactant system and a carrier that is stable in the presence of the cationic active ingredient. The oral composition can be provided in a dual tube or single tube form, if desired.
Abstract translation: 提供一种口服组合物，其覆盖一种或多种阳离子活性成分和具有基本上对阳离子活性成分惰性的多孔表面的阳离子相容的无机颗粒。 口服组合物还具有阳离子相容的表面活性剂体系和在阳离子活性成分存在下是稳定的载体。 如果需要，口服组合物可以以双管或单管形式提供。
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公开(公告)号：WO2006071404A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/042163
申请日：2005-11-18
Applicant: COLGATE-PALMOLIVE COMPANY , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
Inventor： ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
CPC classification number: A61K8/97 , A61K2800/43 , A61Q11/00
Abstract: Low water tooth pastes contain a variety of plant extracts. The oral or dentifrice compositions containing humectants, abrasive compounds, and a variety of plant extracts, such as rosemary and green tea extracts, along with an additional antioxidant component. Examples of antioxidants include stannous compounds, sodium meta-bisulfite, BHT, ammonium sulfate, and potassium stannate. The compositions are resistant to browning. The invention also provides methods for promoting oral health of a subject animal comprising applying a composition as discussed above to the oral surfaces of the animal.
Abstract translation: 低水牙膏含有各种植物提取物。 含有湿润剂，磨料化合物和各种植物提取物如迷迭香和绿茶提取物的口服或牙粉组合物以及另外的抗氧化成分。 抗氧化剂的实例包括亚锡化合物，偏亚硫酸氢钠，BHT，硫酸铵和锡酸锡。 组合物耐褐变。 本发明还提供用于促进受试动物的口腔健康的方法，包括将如上所述的组合物施用于动物的口腔表面。
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公开(公告)号：WO2006069210A3
公开(公告)日：2006-06-29
申请号：PCT/US2005/046522
申请日：2005-12-21
Applicant: COLGATE-PALMOLIVE COMPANY , XU, Guofeng , BOYD, Thomas, J. , HAO, Zhigang , VISCIO, David , GAFFAR, Abdul , MELLO, Sarita, V. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
Inventor： XU, Guofeng , BOYD, Thomas, J. , HAO, Zhigang , VISCIO, David , GAFFAR, Abdul , MELLO, Sarita, V. , ARVANITIDOU, Evangelia, S. , PRENCIPE, Michael
IPC: A61Q11/02 , A61Q11/00 , A61K8/19 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/29 , A61K8/49 , A61K8/81 , A61P29/00
Abstract: Oral care compositions containing: a free-B-ring flavonoid and a flavan; as well as at least one bioavailability-enhancing agent are provided. Methods of using the oral compositions are also provided.
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65.发明申请
公开(公告)号：WO2005037127A1
公开(公告)日：2005-04-28
申请号：PCT/US2004/033502
申请日：2004-10-12
Applicant: COLGATE-PALMOLIVE COMPANY , PRENCIPE, Michael , CHOPRA, Suman , NORRIS, Joseph, T. , SERRANO, Adolfo
Inventor： PRENCIPE, Michael , CHOPRA, Suman , NORRIS, Joseph, T. , SERRANO, Adolfo
IPC: A61C19/06
CPC classification number: A61C19/066 , A46B9/005 , A46B9/021 , A46B9/025 , A46B11/0024 , A46B11/0027 , A46B17/04 , A46B2200/10 , A46B2200/1046 , A46B2200/20 , A61C1/0092 , A61C3/005 , A61C17/0202 , A61C19/063 , A61K8/22 , A61K8/8147 , A61K2800/87 , A61K2800/92 , A61Q11/00
Abstract: The method of the present invention is directed to the storage and dispensing of a peroxide containing tooth whitening composition. During storage and subsequent use the composition in the storage chamber must be maintained segregated from the applicator surface. This is accomplished by delivering the peroxide containing tooth whitening composition from the storage chamber through a delivery channel having a length and a cross-sectional diameter sufficient to preclude the migration of moisture and the enzyme catalase from the application surface to the storage chamber. The composition is applied to teeth by means of bristles, a sponge surface or fibrillated surface. This applicator can be used with both aqueous and non-aqueous peroxide containing tooth whitening compositions.
Abstract translation: 本发明的方法涉及含过氧化物的牙齿增白组合物的储存和分配。 在储存和随后使用期间，储存室中的组合物必须保持与施用器表面分离。 这是通过将来自储存室的含过氧化物的牙齿增白组合物通过具有足以防止水分和酶过氧化氢酶从施用表面迁移到储存室的长度和横截面直径的输送通道来实现的。 组合物通过刷毛，海绵表面或原纤化表面施加到牙齿上。 该施用器可以与含水和非水过氧化物含有牙齿美白组合物一起使用。
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Patent Agency Ranking
公开(公告)号：WO2018118161A1
公开(公告)日：2018-06-28
申请号：PCT/US2017/052183
申请日：2017-09-19
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： REGE, Aarti , PRENCIPE, Michael , THOMSON, Paul
Abstract: This invention relates to oral care compositions comprising a zinc source comprising zinc oxide and zinc citrate; a stannous source comprising stannous pyrophosphate; a fluoride ion source comprising sodium fluoride; and an organic buffer, as well as to methods of using and of making these compositions.
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公开(公告)号：WO2018118138A1
公开(公告)日：2018-06-28
申请号：PCT/US2017/046287
申请日：2017-08-10
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： REGE, Aarti , PRENCIPE, Michael , ESTRIPLET, Marc
Abstract: An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.
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公开(公告)号：WO2017223497A1
公开(公告)日：2017-12-28
申请号：PCT/US2017/039084
申请日：2017-06-23
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： POTH, Tilo , POTANIN, Andrei , BLANVALET, Claude , WON, Betty , MANUS, Lisa , STRANICK, Michael A. , HUANG, Xiaoyi , PRENCIPE, Michael , RUSSO, Amy , STETTLER, Hansruedi , YAN, Peng , TAN, Chengkang , PATEL, Vyoma , MORGAN, Andre Michelle
Abstract: Described herein are oral care compositions comprising an amino acid; a combination of zinc ion sources; and a thickening system comprising a nonionic cellulose ether having a molecular weight of from about 300,000 to about 350,000; and a polysaccharide gum; along with methods of making and using same.
Abstract translation: 本文描述了包含氨基酸的口腔护理组合物; 锌离子源的组合; 和增稠体系，其包含分子量为约300,000至约350,000的非离子纤维素醚; 和多糖胶; 以及制作和使用它们的方法。
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公开(公告)号：WO2017223311A1
公开(公告)日：2017-12-28
申请号：PCT/US2017/038741
申请日：2017-06-22
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： REGE, Aarti , PRENCIPE, Michael , BHADRA, Madhuleena
Abstract: An oral care composition comprising zinc phosphate, stannous fluoride and an organic acid buffer system, as well as methods of using the same.
Abstract translation: 包含磷酸锌，氟化亚锡和有机酸缓冲体系的口腔护理组合物，以及使用其的方法。
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公开(公告)号：WO2017003856A1
公开(公告)日：2017-01-05
申请号：PCT/US2016/039226
申请日：2016-06-24
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor： THOMSON, Paul , DOGU, Nihal , PRENCIPE, Michael , RUSSO, Amy , STETTLER, Hans , MORGAN, Andre Michelle
CPC classification number: A61K8/44 , A61K8/21 , A61K8/25 , A61K8/27 , A61K8/345 , A61K8/362 , A61K8/365 , A61K2800/28 , A61K2800/92 , A61Q11/00
Abstract: This invention relates to oral care compositions comprising a basic amino acid in free or salt from (e.g., free form arginine); zinc oxide and zinc citrate; and a fluoride source comprising stannous fluoride.
Abstract translation: 本发明涉及包含游离或盐的碱性氨基酸（例如游离形式的精氨酸）的口腔护理组合物; 氧化锌和柠檬酸锌; 和含氟化亚锡的氟化物源。
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