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公开(公告)号：DK3150198T3
公开(公告)日：2021-11-01
申请号：DK16185289
申请日：2011-04-07
Applicant: VERTEX PHARMA
Inventor： VERWIJS MARINUS JACOBUS , ALARGOVA ROSSITZA GUEORGUIEVA , KAUSHIK RITU ROHIT , KADIYALA IRINA NIKOLAEVNA , YOUNG CHRISTOPHER RYAN
IPC: A61K9/16 , A61K9/20 , A61K9/28 , C07D213/75 , C07D405/12 , C07D405/14
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公开(公告)号：PL3345625T3
公开(公告)日：2021-06-14
申请号：PL17204189
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：RS61408B1
公开(公告)日：2021-03-31
申请号：RSP20210129
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：RS58604B1
公开(公告)日：2019-05-31
申请号：RSP20190432
申请日：2010-02-18
Applicant: VERTEX PHARMA
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公开(公告)号：DK2464337T3
公开(公告)日：2019-04-23
申请号：DK10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
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Patent Agency Ranking
公开(公告)号：RS57831B1
公开(公告)日：2018-12-31
申请号：RSP20181318
申请日：2013-11-01
Applicant: VERTEX PHARMA
Inventor： VERWIJS MARINUS JACOBUS , KARKARE RADHIKA , MOORE MICHAEL DOUGLAS
IPC: A61K9/20 , A61K31/443 , A61K31/47 , A61K45/06
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公开(公告)号：SI2328618T1
公开(公告)日：2018-04-30
申请号：SI200931803
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：AU2016213697B2
公开(公告)日：2018-04-05
申请号：AU2016213697
申请日：2016-08-08
Applicant: VERTEX PHARMA
Inventor： VERWIJS MARINUS JACOBUS , ALARGOVA ROSSITZA GUEORGUIEVA , KAUSHIK RITU ROHIT , KADIYALA IRINA NIKOLAEVNA , YOUNG CHRISTOPHER RYAN
IPC: A61K9/20
Abstract: A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2 difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient.
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公开(公告)号：DK2328618T3
公开(公告)日：2018-02-19
申请号：DK09789125
申请日：2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号：AU2016216569A1
公开(公告)日：2016-09-01
申请号：AU2016216569
申请日：2016-08-16
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , VERWIJS MARINUS JACOBUS
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3 carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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