-
公开(公告)号：WO2018030709A1
公开(公告)日：2018-02-15
申请号：PCT/KR2017/008370
申请日：2017-08-03
Applicant: 한국기초과학지원연구원
IPC: G01N1/38 , G01N33/483
CPC classification number: G01N1/38 , G01N33/483
Abstract: 본 발명은 고흡수성 수지를 이용한 시료의 전처리 방법 및 이를 위한 디바이스에 관한 것이다. 보다 구체적으로, 본 발명은 고흡수성 수지(Super Absorbent Polymer, SAP)를 이용하여 원심분리 단계 없이도 액체-액체층을 분리하기 위한 시료의 전처리 방법 및 이를 위한 디바이스에 관한 것이다.
Abstract translation: 本发明涉及一种使用超吸收性树脂对样品进行预处理的方法及其装置。 更具体地，没有液体使用本发明的超吸收性树脂（高吸水性树脂，SAP）离心步骤一涉及的样品的方法的预处理用于分离液体层和为此的装置。
-
公开(公告)号：WO2020054922A1
公开(公告)日：2020-03-19
申请号：PCT/KR2019/000712
申请日：2019-01-17
Applicant: 한국기초과학지원연구원
IPC: G01N1/38 , G01N33/487
Abstract: 본 발명은 고흡수성 수지 비드(Super Absorbent Polymer Bead, SAPB)로 채워진 스핀 컬럼을 이용한 지질체의 추출방법 및 상기 고흡수성 수지 비드를 이용한 지질체 추출 키트에 관한 것이다. 본 발명에 따른 지질체의 추출 방법은 종래 Folch 방법 및 SAP 방법에 비해 민감도. 재현성 그리고 정량성이 우수한 장점이 있다.
-
公开(公告)号：KR100772078B1
公开(公告)日：2007-10-31
申请号：KR1020060109667
申请日：2006-11-07
Applicant: 한국기초과학지원연구원 , 재단법인서울대학교산학협력재단
IPC: C07H1/06
Abstract: Novel monogalactosyldiacylglycerol compounds isolated from Sargassum Thunbergii are provided which shows anti-fungal activity on Candida albican and contains both alpha-linoleic acid and eicosapentaenoic acid(EPA). A [(2S)-1-O-(5Z,8Z,11Z,14Z,17Z -eicosapentaenoyl)-2-O-(9Z,12Z,15Z-octadecatrienoyl)-3-O-beta-Dgalactopyranosyl-sn-glycerol] is represented by the formula(1). A (2S)-1-O-(9Z,12Z,15Z-octadecatrienoyl)-2-O-(6Z,9Z,12Z,15Z-octadecatetraenoyl)-3-O-beta-D-galactopyranosyl-sn-glycerol is represented by the formula(2). A method for preparing the monogalactosyldiacylglycerol compound comprises the steps of: (a) after mixing cut Sargassum Thunbergii with methanol in a weight ratio of 1:1-1:3 and leaving it for 48-72 hours, filtering it; (b) concentrating the methanol filtrate under reduced pressure and adding a mixture solution of butanol and water in a weight ratio of 1:1 thereto; (c) concentrating solvent of the butanol layer under reduced pressure and adding a mixture solution consisting of methanol and water in a weight ratio of 15:85 and normal hexane thereto; and (d) concentrating solvent of the methanol layer under reduced pressure and isolating the desired product through a reverse silica flash chromatography.
Abstract translation: 提供了从马齿苋（Thargarum Thunbergii）分离的新型单糖半乳糖二甘油化合物，其显示白念珠菌（Candida albican）的抗真菌活性，并含有α-亚油酸和二十碳五烯酸（EPA）。 A [（2S）-1-O-（5Z，8Z，11Z，14Z，17Z-二十碳烯酰基）-2-O-（9Z，12Z，15Z-十八碳三烯酰基）-3-O-β-D-吡喃半乳糖基-sn-甘油] 由式（1）表示。 代表了（2S）-1-O-（9Z，12Z，15Z-十八碳三烯酰基）-2-O-（6Z，9Z，12Z，15Z-十八碳四烯酰基）-3-O-β-D-吡喃半乳糖基-sn-甘油 通过式（2）。 制备单半乳糖基二酰基甘油化合物的方法包括以下步骤：（a）将切碎的马鞭草皂甙与甲醇以1：1-1：3的重量比混合48-72小时后，过滤; （b）减压浓缩甲醇滤液，加入重量比为1:1的丁醇和水的混合溶液; （c）在减压下浓缩丁醇层的溶剂，并加入由甲醇和水组成的重量比为15:85的混合溶液和正己烷; 和（d）减压浓缩甲醇层的溶剂，并通过反向硅胶快速色谱法分离所需产物。
-
公开(公告)号：KR1020130046178A
公开(公告)日：2013-05-07
申请号：KR1020110110590
申请日：2011-10-27
Applicant: 한국기초과학지원연구원
IPC: G06F19/00
CPC classification number: G06F19/709 , G06F17/3071
Abstract: PURPOSE: A chemical composition judgment device and a method thereof are provided to automatically analyze the chemical composition of a lipid body from a mass spectrum with high precision in consideration of isotope information organized in a database. CONSTITUTION: A judgment device for the chemical composition of a lipid body is composed of a lipid body information input part(101), a user parameter input part(102), a chemical composition analysis part(103), a lipid body database(104), and a result information output part(105). The lipid body information input part takes charge of the input of spectrum information(501) obtained from a lipid body sample through a mass spectrometer, and the user parameter input part inputs the charge state of the mass spectrometer at the point of obtaining a mass spectrum, an adduct type, and a mass error range considered when automatically granting a chemical composition from the mass, as the parameters required for a precise chemical composition analysis. The chemical composition analysis part is a part automatically granting chemical composition information from the mass spectrum by mutually comparing and analyzing the mass spectrum information inputted from the lipid body information input part and the mass spectrum information for each chemical composition already stored in the lipid body database, by considering the user parameters inputted from the user parameter input part. The result information output part outputs the final result of the chemical composition analysis part. [Reference numerals] (101) Lipid body information input part; (102) User parameter input part; (103) Chemical composition analysis part; (104) Lipid body database; (105) Result information output part
Abstract translation: 目的：提供化学成分判断装置及其方法，以考虑到数据库中组织的同位素信息，以高精度自动分析质谱的脂质体的化学成分。 构成：脂质体的化学成分的判断装置由脂质体信息输入部（101），使用者参数输入部（102），化学成分分析部（103），脂质体数据库（104） ）和结果信息输出部（105）。 脂质体信息输入部通过质谱仪负责从脂质体样品获得的光谱信息（501）的输入，用户参数输入部在获得质谱时输入质谱仪的电荷状态 ，加合物类型和质量误差范围考虑，作为精确的化学成分分析所需要的参数。 化学成分分析部分是通过相互比较和分析从脂质体信息输入部输入的质谱信息和已经存储在脂质体数据库中的每种化学成分的质谱信息，自动地从质谱给出化学成分信息的部分 通过考虑从用户参数输入部输入的用户参数。 结果信息输出部分输出化学成分分析部分的最终结果。 （101）脂质体信息输入部; （102）用户参数输入部分; （103）化学成分分析部分; （104）脂质体数据库; （105）结果信息输出部分
-
公开(公告)号：KR101570143B1
公开(公告)日：2015-11-20
申请号：KR1020140061542
申请日：2014-05-22
Applicant: 국립암센터 , 한국기초과학지원연구원
IPC: G01N33/50 , G01N33/574 , G01N27/62 , G01N30/72
CPC classification number: G01N33/50 , G01N27/62 , G01N30/72 , G01N33/5091 , G01N33/574
Abstract: 본발명은지질발현분석을이용한신장암의진단을위한정보제공방법에관한것으로서, 보다구체적으로는, C24-OH 설파티드(sulfatide), C22-OH 설파티드, PC(포스파티딜콜린){34:1} 및 PC{36:2} 로이루어진군으로부터선택되는하나이상의지질의발현을분석하는단계를포함하는신장암의진단을위한정보제공방법에관한것이다. 또한, 본발명은 MALDI MS (MALDI 질량분석; matrix-assisted laser desorption/ionization mass spectrometry) 를이용하여신세포암 (또는신장암) (renal cell carcinoma) 의진단을위한정보를제공하는방법에관한것이다. 본발명의방법에따라, 적은샘플의양으로간단하면서도높은정확도로신장암을진단할수 있으며, 신장암의하위유형으로서, 투명세포형, 유두형및 난염형의신장암을간단하고높은정확도로감별해낼수 있고, 신장암의하위유형으로서의투명세포형신장암과비투명세포형신장암을간단하고높은정확도로감별해낼수 있다.
Abstract translation: 本发明涉及通过使用脂质表达分析提供诊断肾细胞癌的信息的方法，更具体地，涉及提供用于诊断肾细胞癌的信息的方法，包括分析至少一种选自以下的脂质的表达的步骤： 包括C24-OH硫苷脂，C22-OH硫苷脂，PC（磷脂酰胆碱）（34:1）和PC（36：2）的组。 此外，本发明涉及通过使用MALDI MS（MALDI质谱法;基质辅助激光解吸/电离质谱法）提供诊断肾细胞癌的信息的方法。 本发明的方法可以用少量样品以高精度诊断肾细胞癌，并且可以区分为细胞型肾细胞癌，乳头状肾细胞癌和非透明细胞型肾细胞的亚型 癌症具有高精度。
-
Patent Agency Ranking
公开(公告)号：KR102118067B1
公开(公告)日：2020-06-03
申请号：KR1020180109563
申请日：2018-09-13
Applicant: 한국기초과학지원연구원
IPC: G01N1/38 , G01N33/487
-
公开(公告)号：KR101816288B1
公开(公告)日：2018-01-09
申请号：KR1020170069036
申请日：2017-06-02
Applicant: 한국기초과학지원연구원
IPC: G01N1/38 , G01N33/483
CPC classification number: G01N1/38 , G01N33/483 , C08J2300/14 , G01N33/4833 , G01N2001/385
Abstract: 본발명은고흡수성수지를이용한시료의전처리방법및 이를위한디바이스에관한것이다. 보다구체적으로, 본발명은고흡수성수지(Super Absorbent Polymer, SAP)를이용하여원심분리단계없이도액체-액체층을분리하기위한시료의전처리방법및 이를위한디바이스에관한것이다.
Abstract translation: 本发明涉及使用超吸收性树脂的样品的预处理方法及其装置。 更具体地，没有液体使用本发明的超吸收性树脂（高吸水性树脂，SAP）离心步骤一涉及用于分离液体层及装置的样品的方法的预处理。
-
公开(公告)号：KR1020090036030A
公开(公告)日：2009-04-13
申请号：KR1020070101118
申请日：2007-10-08
Applicant: 삼성전자주식회사 , 재단법인서울대학교산학협력재단
IPC: H01P3/08
CPC classification number: H01P11/001 , H01P3/003 , H01P3/081 , Y10T29/49016
Abstract: A multi-metal waveguide and manufacturing method thereof is provided to minimize loss by increasing a current distribution area through insertion of an insulating layer between metal layers. A plurality of metal layers is laminated on a substrate while a power transmission line which is composed of a plurality of metal including a signal line(200). The signal line comprises a first signal part(210) and a second signal part(220). The first signal part is formed in at least one of metal layers and is formed with separated with a ground line. The second signal part has the width wider than that of the first signal part while being separated with the ground line by a different height. The transmission line of the multi-metal includes a metal connection unit(300).
Abstract translation: 提供多金属波导及其制造方法，以通过在金属层之间插入绝缘层来增加电流分布面积来最小化损耗。 多个金属层层叠在基板上，而由包括信号线（200）的多个金属构成的输电线路。 信号线包括第一信号部分（210）和第二信号部分（220）。 第一信号部分形成在金属层中的至少一个中，并且被形成为用接地线分开。 第二信号部分的宽度比第一信号部分的宽度宽，同时用接地线分开不同的高度。 多金属的传输线包括金属连接单元（300）。
-
公开(公告)号：KR101425796B1
公开(公告)日：2014-08-04
申请号：KR1020070101118
申请日：2007-10-08
Applicant: 삼성전자주식회사 , 재단법인서울대학교산학협력재단
IPC: H01P3/08
CPC classification number: H01P11/001 , H01P3/003 , H01P3/081 , Y10T29/49016
Abstract: 본 발명은 다층 금속 구조체의 전송선로 및 이의 형성 방법에 관한 것으로, 기판상에 다수의 금속층을 적층하되, 각 금속층간에 절연층이 삽입되는 다층 금속 구조체의 전송선로에 있어서, 신호선과 접지선 사이의 전류 분포를 넓은 면적에 분산하여 도전체 손실을 최소화할 수 있도록 한 것이다.
다층 금속 구조, 전송선로, 신호선, 접지선, 손실-
公开(公告)号：KR1020090028880A
公开(公告)日：2009-03-20
申请号：KR1020070093995
申请日：2007-09-17
Applicant: 재단법인서울대학교산학협력재단
IPC: A61K31/198 , A61K31/13 , A61P11/00 , A61P1/16
CPC classification number: A61K31/198
Abstract: A pharmaceutical composition including a transglutaminase(TGase 2) inhibitor or N-acetylcysteine(NAC) is provided to prevent or cure fibrosis and to specifically show the molecular mechanism about the fibrosis. A pharmaceutical composition for preventing and treating fibrosis comprises (a) pharmaceutically effective dose of a transglutaminase(TGase 2) inhibitor or N-acetylcysteine(NAC); and (b)a pharmaceutically allowable carrier. A screening method of a material for preventing and treating fibrosis comprises the steps of: (i) contacting a testing material with a transglutaminase(TGase 2) protein; and (ii) measuring the activity of the TGase 2. The transglutaminase(TGase 2) inhibitor is the cystamine or the cysteamine.
Abstract translation: 提供包含转谷氨酰胺酶（TGase 2）抑制剂或N-乙酰半胱氨酸（NAC）的药物组合物，以预防或治愈纤维化，并具体显示纤维化的分子机制。 用于预防和治疗纤维化的药物组合物包括（a）药学有效剂量的转谷氨酰胺酶（TGase 2）抑制剂或N-乙酰半胱氨酸（NAC）; 和（b）药学上可允许的载体。 用于预防和治疗纤维化的材料的筛选方法包括以下步骤：（i）使测试材料与转谷氨酰胺酶（TGase 2）蛋白质接触; 和（ii）测量TGase 2的活性。转谷氨酰胺酶（TGase 2）抑制剂是胱胺胺或半胱胺。
-
-
-
-
-
-
-
-
-
Search Results
10
records
(took 0.021 seconds)
