公开(公告)号：US08300228B2

公开(公告)日：2012-10-30

申请号：US12582168

申请日：2009-10-20

Applicant: Daniel L. Marks ,  Joseph B. Geddes, III ,  Stephen A. Boppart

Inventor： Daniel L. Marks ,  Joseph B. Geddes, III ,  Stephen A. Boppart

IPC: G01B9/02

CPC classification number: G01J3/44 ,  G01J3/10 ,  G01J3/4531 ,  G01J9/02

Abstract: Methods and apparatus for selectively driving the vibrations of normal modes of a target molecule into coherence using stimulated Raman scattering. In concert, many vibrations produce a larger anti-Stokes signal than a single vibration. The same illumination does not drive other molecules to have coherent vibrations, so these molecules produce a weaker signal. Target and confounder molecules can be distinguished by pulses that drive many vibrations coherently, with applications in coherent Raman microspectroscopy.

Abstract translation: 使用受激拉曼散射选择性地将目标分子的正常模式的振动驱动到相干性的方法和装置。 在一致的情况下，许多振动产生比单个振动更大的反斯托克斯信号。 相同的照明不会驱使其他分子具有相干的振动，所以这些分子产生较弱的信号。 目标和混杂分子可以通过相干拉曼光谱中应用的脉冲来区分。

公开(公告)号：US20120050744A1

公开(公告)日：2012-03-01

申请号：US13192577

申请日：2011-07-28

Applicant: Kazumasa TAKADA ,  Katsunari OKAMOTO

Inventor： Kazumasa TAKADA ,  Katsunari OKAMOTO

IPC: G01J3/45

CPC classification number: G01J3/4531 ,  G01J3/45 ,  G01J3/4532

Abstract: A transform spectrometer measurement apparatus and method for a planar waveguide circuit (PLC). The spectrometer typically includes an input optical signal waveguide carrying an input optical signal; a plurality of couplers, each connected to the input optical signal waveguide, and each including a coupler output for carrying a coupled optical signal related to the input optical signal; and an array of interleaved, waveguide Mach-Zehnder interferometers (MZI), each having at least one input MZI waveguide, each MZI input waveguide receiving a coupled optical signal from a respective coupler output. A phase shifting circuit is applied to at least one arm of the MZIs to induce an active phase shift on the arm to thereby measure phase error in the MZIs. Light output from the MZIs is measured under intrinsic phase error conditions and after an active phase shift by the phase shifting circuit.

Abstract translation: 一种用于平面波导电路（PLC）的变换光谱仪测量装置和方法。 光谱仪通常包括承载输入光信号的输入光信号波导; 多个耦合器，各自连接到输入光信号波导，并且每个耦合器包括耦合器输出，用于承载与输入光信号相关的耦合光信号; 以及每个具有至少一个输入MZI波导的交错的波导马赫 - 策德尔干涉仪阵列（MZI），每个MZI输入波导从相应的耦合器输出接收耦合的光信号。 移相电路施加到MZI的至少一个臂，以引起臂上的有源相移，从而测量MZI中的相位误差。 来自MZI的光输出在固有相位误差条件下测量，并在相移电路进行有源相移之后测量。

公开(公告)号：US08098379B2

公开(公告)日：2012-01-17

申请号：US12710765

申请日：2010-02-23

Applicant: Katsunari Okamoto

Inventor： Katsunari Okamoto

IPC: G01J3/45

CPC classification number: G01J3/4531 ,  G02F1/3136 ,  Y10T29/49002

Abstract: A transform spectrometer implemented on a planar waveguide circuit (PLC), having an input optical signal waveguide carrying an input optical signal to be analyzed; a plurality of couplers, each connected to the input optical signal waveguide, and each including a coupler output for carrying a coupled optical signal related to the input optical signal. An array of interleaved, asymmetrical waveguide Mach-Zehnder interferometers (MZI) is formed on the PLC, each having at least one input MZI waveguide, each MZI input waveguide receiving a coupled optical signal from a respective coupler output; wherein at least some of the input MZI waveguides intersect in a common layer of the PLC, at an angle which allows their respective coupled optical signals to transmit without unacceptable attenuation. This arrangement improves spatial efficiency of the PLC, allowing more MZIs to be implemented, resulting in increased spectral resolution.

Abstract translation: 实现在平面波导电路（PLC）上的变换光谱仪，具有承载要分析的输入光信号的输入光信号波导; 多个耦合器，每个耦合器连接到输入光信号波导，并且每个耦合器包括耦合器输出，用于承载与输入光信号相关的耦合光信号。 在PLC上形成交错的非对称波导马赫 - 曾德干涉仪（MZI）阵列，每个波导具有至少一个输入MZI波导，每个MZI输入波导从相应的耦合器输出接收耦合的光信号; 其中输入MZI波导中的至少一些波导在PLC的公共层中以允许它们各自的耦合的光信号传输而没有不可接受的衰减的角度相交。 这种布置提高了PLC的空间效率，允许实现更多的MZI，从而提高了光谱分辨率。

公开(公告)号：US08018597B2

公开(公告)日：2011-09-13

申请号：US12142860

申请日：2008-06-20

Applicant: Alan Douglas Scott

Inventor： Alan Douglas Scott

IPC: G01B9/02 ,  G01J3/45

CPC classification number: G01J3/4532 ,  G01J3/02 ,  G01J3/024 ,  G01J3/0259 ,  G01J3/0289 ,  G01J3/0294 ,  G01J3/1895 ,  G01J3/4531 ,  G02B6/29352 ,  G02B6/29358 ,  G02B6/29389 ,  G02B6/30 ,  G02B2006/12119 ,  G02B2006/12159

Abstract: An optical broadband micro-spectrometer containing an input optical assembly, a group of slab waveguide spatial heterodyne spectrometer (SHS) integrated circuits (ICs), a detection module and a processor for multi-line detection. The input optical assembly applies an input light signal uniformly with respect to brightness and frequency to the apertures of the waveguides and may project a pupil image onto the SHS input face and may be a scanner. Each slab waveguide spatial heterodyne spectrometer (SHS) integrated circuit (IC) contains at least one slab waveguide SHS IC. The detection module bonds directly to the slab waveguide output apertures. Each slab waveguide SHS IC may contain one or more slab waveguide SHS.

Abstract translation: 一种含有输入光学组件，一组平板波导空间外差光谱仪（SHS）集成电路（IC），检测模块和用于多线检测的处理器的光学宽带微光谱仪。 输入光学组件将输入光信号相对于亮度和频率均匀地施加到波导的孔，并且可以将瞳孔图像投影到SHS输入面上，并且可以是扫描仪。 每个平板波导空间外差谱仪（SHS）集成电路（IC）包含至少一个平板波导SHS IC。 检测模块直接连接到平板波导输出孔。 每个平板波导SHS IC可以包含一个或多个平板波导SHS。

公开(公告)号：US07903254B2

公开(公告)日：2011-03-08

申请号：US12538309

申请日：2009-08-10

Applicant: Adam Wax ,  John W. Pyhtila

Inventor： Adam Wax ,  John W. Pyhtila

IPC: G01B9/02 ,  G01J3/45 ,  G01N21/00

CPC classification number: G01J3/4412 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/7257 ,  G01B9/02044 ,  G01B9/02084 ,  G01B9/02087 ,  G01B9/0209 ,  G01J3/4531 ,  G01N21/31 ,  G01N21/4795 ,  G01N2021/4704 ,  G01N2021/4709 ,  G01N2021/4735 ,  G01N2201/08

Abstract: Fourier domain a/LCI (faLCI) system and method which enables in vivo data acquisition at rapid rates using a single scan. Angle-resolved and depth-resolved spectra information is obtained with one scan. The reference arm can remain fixed with respect to the sample due to only one scan required. A reference signal and a reflected sample signal are cross-correlated and dispersed at a multitude of reflected angles off of the sample, thereby representing reflections from a multitude of points on the sample at the same time in parallel. Information about all depths of the sample at each of the multitude of different points on the sample can be obtained with one scan on the order of approximately 40 milliseconds. From the spatial, cross-correlated reference signal, structural (size) information can also be obtained using techniques that allow size information of scatterers to be obtained from angle-resolved data.

Abstract translation: 傅里叶域a / LCI（faLCI）系统和方法，使用单次扫描能够以快速的速率进行体内数据采集。 通过一次扫描获得角度分辨和深度分辨的光谱信息。 由于仅需要一次扫描，参考臂可以相对于样品保持固定。 参考信号和反射的采样信号以相对于样本的多个反射角度相互相关并分散，从而同时并行地表示来自样品上的多个点的反射。 可以通过大约40毫秒量级的一次扫描获得关于样本上多个不同点的每个样本的所有深度的信息。 从空间相互关联的参考信号，也可以使用允许从角度分辨数据获得散射体的尺寸信息的技术来获得结构（尺寸）信息。

公开(公告)号：US20100314545A1

公开(公告)日：2010-12-16

申请号：US12861651

申请日：2010-08-23

Applicant: Ronald T. Logan, JR. ,  Joseph R. Demers

Inventor： Ronald T. Logan, JR. ,  Joseph R. Demers

IPC: G01J5/02 ,  G01J3/28

CPC classification number: G01J3/427 ,  A61B5/0507 ,  G01J3/10 ,  G01J3/42 ,  G01J3/4531 ,  G01N21/3581 ,  G01N21/3586 ,  G01N21/39

Abstract: An apparatus for analyzing, identifying or imaging an target including first and second laser beams coupled to a pair of photoconductive switches to produce CW signals in one or more bands in a range of frequencies greater than 100 GHz focused on and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral heterodyne process to generate an electrical signal representative of some characteristics of the target. The lasers are tuned to different frequencies and a frequency shifter in the path of one laser beam allows the terahertz beam to be finely adjusted in one or more selected frequency bands.

Abstract translation: 一种用于分析，识别或成像目标的装置，包括耦合到一对光电导开关的第一和第二激光束，以在大于100GHz的频率的范围内的一个或多个频带中产生CW信号，该信号集中于并经由 目标; 以及检测器，用于从从目标接收的信号中获取光谱信息，并使用多光谱外差处理产生表示目标的某些特性的电信号。 将激光器调谐到不同的频率，并且在一个激光束的路径中的频移器允许在一个或多个所选频带中微调太赫兹波束。

公开(公告)号：US20100245831A1

公开(公告)日：2010-09-30

申请号：US12710765

申请日：2010-02-23

Applicant: Katsunari OKAMOTO

Inventor： Katsunari OKAMOTO

IPC: G01J3/45 ,  H05K13/00

CPC classification number: G01J3/4531 ,  G02F1/3136 ,  Y10T29/49002

Abstract: A transform spectrometer implemented on a planar waveguide circuit (PLC), having an input optical signal waveguide carrying an input optical signal to be analyzed; a plurality of couplers, each connected to the input optical signal waveguide, and each including a coupler output for carrying a coupled optical signal related to the input optical signal. An array of interleaved, asymmetrical waveguide Mach-Zehnder interferometers (MZI) is formed on the PLC, each having at least one input MZI waveguide, each MZI input waveguide receiving a coupled optical signal from a respective coupler output; wherein at least some of the input MZI waveguides intersect in a common layer of the PLC, at an angle which allows their respective coupled optical signals to transmit without unacceptable attenuation. This arrangement improves spatial efficiency of the PLC, allowing more MZIs to be implemented, resulting in increased spectral resolution.

Abstract translation: 实现在平面波导电路（PLC）上的变换光谱仪，具有承载要分析的输入光信号的输入光信号波导; 多个耦合器，每个耦合器连接到输入光信号波导，并且每个耦合器包括耦合器输出，用于承载与输入光信号相关的耦合光信号。 在PLC上形成交错的非对称波导马赫 - 曾德干涉仪（MZI）阵列，每个波导具有至少一个输入MZI波导，每个MZI输入波导从相应的耦合器输出接收耦合的光信号; 其中输入MZI波导中的至少一些波导在PLC的公共层中以允许它们各自的耦合的光信号传输而没有不可接受的衰减的角度相交。 这种布置提高了PLC的空间效率，允许实现更多的MZI，从而提高了光谱分辨率。

公开(公告)号：US20100171952A1

公开(公告)日：2010-07-08

申请号：US12676536

申请日：2008-09-08

Applicant: Lauren DeFlores ,  Andrei Tokmakoff

Inventor： Lauren DeFlores ,  Andrei Tokmakoff

IPC: G01J3/12 ,  G01J3/00 ,  G01J3/28 ,  G01J3/447

CPC classification number: G01J3/42 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/4531 ,  G01N21/35 ,  G01N2021/3595

Abstract: The present invention relates to a system and methods for acquiring two-dimensional Fourier transform (2D FT) spectra. Overlap of a collinear pulse pair and probe induce a molecular response which is collected by spectral dispersion of the signal modulated probe beam. Simultaneous collection of the molecular response, pulse timing and characteristics permit real time phasing and rapid acquisition of spectra. Full spectra are acquired as a function of pulse pair timings and numerically transformed to achieve the full frequency-frequency spectrum. This method demonstrates the ability to acquire information on molecular dynamics, couplings and structure in a simple apparatus. Multi-dimensional methods can be used for diagnostic and analytical measurements in the biological, biomedical, and chemical fields.

Abstract translation: 本发明涉及用于获取二维傅里叶变换（2D FT）光谱的系统和方法。 共线脉冲对和探针的重叠引起通过信号调制探测光束的光谱色散收集的分子响应。 同时收集分子响应，脉冲时序和特征允许实时定相和快速采集光谱。 作为脉冲对定时的函数获取全谱，并进行数值变换以实现全频谱。 这种方法证明了在简单的装置中获取分子动力学，耦合和结构信息的能力。 多维方法可用于生物，生物医学和化学领域的诊断和分析测量。

公开(公告)号：US07675037B2

公开(公告)日：2010-03-09

申请号：US11964363

申请日：2007-12-26

Applicant: Yuanjing Li ,  Bing Feng ,  Ziran Zhao ,  Yingxin Wang ,  Dongmei Yu

Inventor： Yuanjing Li ,  Bing Feng ,  Ziran Zhao ,  Yingxin Wang ,  Dongmei Yu

IPC: G01J5/02

CPC classification number: G01J3/42 ,  G01J3/4531 ,  G01N21/3586

Abstract: A method and an apparatus for measuring terahertz time-domain spectrum, which relate to the field of terahertz time-domain spectrum. The method comprises the steps of: generating a first pulse laser beam from a first femtosecond laser device at a preset repetition frequency to generate THz pulses; generating a second pulse laser beam from a second femtosecond laser device at the repetition frequency; measuring electric field intensities of the THz pulses at respective phase differences between the first pulse laser beam and the second pulse laser beam; and obtaining a THz time-domain spectroscopy by performing Fourier transformation of data representative of the electric field intensities. THz spectrum measured according to the method and apparatus improves spectroscopy resolution and provides a broader detection range.

Abstract translation: 一种用于测量太赫兹时域光谱的方法和装置，涉及太赫兹时域光谱领域。 该方法包括以下步骤：以预设的重复频率从第一飞秒激光装置产生第一脉冲激光束以产生THz脉冲; 以重复频率从第二飞秒激光装置产生第二脉冲激光束; 在第一脉冲激光束和第二脉冲激光束之间的相位差测量THz脉冲的电场强度; 并且通过对代表电场强度的数据进行傅里叶变换来获得THz时域光谱。 根据方法和装置测量的太赫兹光谱提高了光谱分辨率，并提供了更广泛的检测范围。

公开(公告)号：US20090316159A1

公开(公告)日：2009-12-24

申请号：US12142860

申请日：2008-06-20

Applicant: Alan Douglas Scott

Inventor： Alan Douglas Scott

IPC: G01B9/02

CPC classification number: G01J3/4532 ,  G01J3/02 ,  G01J3/024 ,  G01J3/0259 ,  G01J3/0289 ,  G01J3/0294 ,  G01J3/1895 ,  G01J3/4531 ,  G02B6/29352 ,  G02B6/29358 ,  G02B6/29389 ,  G02B6/30 ,  G02B2006/12119 ,  G02B2006/12159

Abstract: An optical broadband micro-spectrometer containing an input optical assembly, a group of slab waveguide spatial heterodyne spectrometer (SHS) integrated circuits (ICs), a detection module and a processor for multi-line detection. The input optical assembly applies an input light signal uniformly with respect to brightness and frequency to the apertures of the waveguides and may project a pupil image onto the SHS input face and may be a scanner. Each slab waveguide spatial heterodyne spectrometer (SHS) integrated circuit (IC) contains at least one slab waveguide SHS IC. The detection module bonds directly to the slab waveguide output apertures. Each slab waveguide SHS IC may contain one or more slab waveguide SHS.

Abstract translation: 一种含有输入光学组件，一组平板波导空间外差光谱仪（SHS）集成电路（IC），检测模块和用于多线检测的处理器的光学宽带微光谱仪。 输入光学组件将输入光信号相对于亮度和频率均匀地施加到波导的孔，并且可以将瞳孔图像投影到SHS输入面上，并且可以是扫描仪。 每个平板波导空间外差谱仪（SHS）集成电路（IC）包含至少一个平板波导SHS IC。 检测模块直接连接到平板波导输出孔。 每个平板波导SHS IC可以包含一个或多个平板波导SHS。