公开(公告)号：US07394542B2

公开(公告)日：2008-07-01

申请号：US10920320

申请日：2004-08-18

Applicant: Thomas Voigt ,  David Tuschel

Inventor： Thomas Voigt ,  David Tuschel

IPC: G01J3/51 ,  G01N21/25 ,  G01N21/62 ,  G01N21/64 ,  G01N21/65

CPC classification number: G01N21/05 ,  B01L3/5027 ,  G01J3/0227 ,  G01J3/4406 ,  G01N21/03 ,  G01N21/31 ,  G01N21/3577 ,  G01N21/64 ,  G01N21/65 ,  G01N2021/0325 ,  G01N2021/0346 ,  G01N2021/651

Abstract: The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which interact with the substance while an attribute of the substance changes to produce a second plurality of photons. The system may also include a filter for receiving the collected photons and providing filtered photons; a photon detector for receiving the filtered photons and obtaining therefrom a spectrum of the substance; and a processor for detecting an aspect of the filtered photons wherein the aspect of the filtered photons is the function of the attribute of the substance.

公开(公告)号：US07327453B2

公开(公告)日：2008-02-05

申请号：US11383410

申请日：2006-05-15

Applicant: David A. Coppeta

Inventor： David A. Coppeta

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/04 ,  G01J3/06 ,  G01J3/10 ,  G01J3/28 ,  G01J2003/065 ,  G01N21/39 ,  G01N21/65 ,  G01N2021/1772 ,  G01N2021/399

Abstract: To achieve a given spectral resolution with reduced detector size and commercially available pixel pitches, the Raman spectrum is shifted across the detector array such as by one of the following methods: 1) tuning the excitation wavelength; 2) rotating the grating; 3) displacing the effective input slit (fiber) and acquiring the spectrum under stepped displacement conditions; and 4) displacement of a lens relative to input fiber to displace effective input slit relative to the detector. A composite spectrum is formed and deconvolution of the entrance aperture image and/or pixel masking is then used.

Abstract translation: 为了获得具有降低的检测器尺寸和市售的像素间距的给定光谱分辨率，拉曼光谱通过检测器阵列移动，例如通过以下方法之一：1）调谐激发波长; 2）旋转光栅; 3）置换有效输入狭缝（光纤）并在阶梯位移条件下获取光谱; 以及4）透镜相对于输入光纤的位移以相对于检测器移位有效的输入狭缝。 形成复合光谱，然后使用入射孔径图像和/或像素掩蔽的去卷积。

公开(公告)号：US20070258089A1

公开(公告)日：2007-11-08

申请号：US11824878

申请日：2007-07-03

Applicant: David Tuschel ,  Thomas Voigt

Inventor： David Tuschel ,  Thomas Voigt

IPC: G01J3/30

CPC classification number: G01N21/05 ,  B01L3/5027 ,  G01J3/0227 ,  G01J3/4406 ,  G01N21/03 ,  G01N21/31 ,  G01N21/3577 ,  G01N21/64 ,  G01N21/65 ,  G01N2021/0325 ,  G01N2021/0346 ,  G01N2021/651

Abstract: The disclosure generally relates to a system for detecting a change in an attribute of a substance. The system may include a photon source for producing a first of a plurality of photons which interact with the substance while an attribute of the substance changes to produce a second plurality of photons. The system may also include a filter for receiving the collected photons and providing filtered photons; a photon detector for receiving the filtered photons and obtaining therefrom a spectrum of the substance; and a processor for detecting an aspect of the filtered photons wherein the aspect of the filtered photons is the function of the attribute of the substance.

Abstract translation: 本发明一般涉及用于检测物质属性变化的系统。 该系统可以包括用于产生与物质相互作用的多个光子中的第一个的光子源，同时物质的属性改变以产生第二多个光子。 该系统还可以包括用于接收所收集的光子并提供经滤光的光子的滤光器; 光子检测器，用于接收经滤光的光子并从中获得物质的光谱; 以及用于检测滤光光子的方面的处理器，其中滤光光子的方面是物质属性的函数。

公开(公告)号：US07286231B2

公开(公告)日：2007-10-23

申请号：US10879630

申请日：2004-06-30

Applicant: John S. Maier ,  Jason H. Neiss ,  Shona Stewart

Inventor： John S. Maier ,  Jason H. Neiss ,  Shona Stewart

IPC: G01J3/51 ,  G01N21/65

CPC classification number: G01J3/28 ,  G01J3/0227 ,  G01J3/027 ,  G01J3/0286 ,  G01J3/44

Abstract: In one embodiment the disclosure relates to a method and a system for determining the corrected wavelength of a photon scattered by a sample. The method includes the steps of determining a wavelength of a photon scattered from a sample exposed to illuminating photons and passed through a tunable filter and correcting the determined wavelength of the photon as a function of the temperature of the tunable filter and as a function of the bandpass set point of the tunable filter. The step of correcting the determined wavelength can further include determining an offset and adding the offset to the determined wavelength of the photon.

Abstract translation: 在一个实施例中，本公开涉及一种用于确定由样本散射的光子的校正波长的方法和系统。 该方法包括以下步骤：确定从暴露于照射光子的样品散射的光子的波长，并且通过可调谐滤光器并校正所确定的光子波长作为可调滤光器的温度的函数，并且作为 可调谐滤波器的带通设定点。 校正所确定的波长的步骤还可以包括确定偏移并将偏移量加到所确定的光子的波长上。

公开(公告)号：US20070241280A1

公开(公告)日：2007-10-18

申请号：US11785341

申请日：2007-04-17

Applicant: Hidetoshi Dainobu ,  Shinji Yamamori

Inventor： Hidetoshi Dainobu ,  Shinji Yamamori

IPC: G01N21/35 ,  G01J5/02

CPC classification number: G01J3/42 ,  G01J3/02 ,  G01J3/0227 ,  G01N21/15 ,  G01N21/3504

Abstract: In an apparatus for measuring concentration of prescribed gas contained in subject gas, a light source is operable to emit infrared light. Airway adapter is adapted to introduce the subject gas, and to allow the infrared light emitted from the light source. A beam splitter is adapted to allow the infrared light which has passed through the airway adapter to be reflected and passed through. A first detector is operable to detect the infrared light which has reflected by the beam splitter. A second detector is operable to detect the infrared light which has passed through the beam splitter. An interference-type notch filter is disposed between the beam splitter and either the first detector or the second detector, the notch filter being adapted to cut a wavelength range of light which is absorbed by the prescribed gas.

Abstract translation: 在用于测量被摄体气体中包含的规定气体的浓度的装置中，光源可操作地发射红外光。 气道适配器适于引入目标气体，并允许从光源发射的红外光。 分束器适于允许穿过气道适配器的红外光被反射并通过。 第一检测器可操作以检测由分束器反射的红外光。 第二检测器可操作以检测已经通过分束器的红外光。 干涉型陷波滤波器设置在分束器与第一检测器或第二检测器之间，陷波滤波器适于切割被规定气体吸收的光的波长范围。

公开(公告)号：US20070109535A1

公开(公告)日：2007-05-17

申请号：US11598245

申请日：2006-11-09

Applicant: John Maier ,  Jeffrey Cohen

Inventor： John Maier ,  Jeffrey Cohen

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0227 ,  G01J3/0291 ,  G01J3/44 ,  G01N21/658 ,  G01N2021/656 ,  G01N2201/129

Abstract: A spectroscopic method and system to identify a biofilm of a microorganism. A sample containing a sample microorganism is irradiated with substantially monochromatic radiation. A Raman data set is obtained based on radiation scattered from the irradiated sample. A database is searched in accordance with the Raman data set in order to identify a known Raman data set from the database. The database contains a plurality of known Raman data sets where each known Raman data set is associated with a known sessile form of a corresponding known microorganism. A sessile form of the sample microorganism is identified based on the known Raman data set identified by the searching.

Abstract translation: 鉴定微生物生物膜的光谱方法和系统。 用基本上单色的辐射照射含有样品微生物的样品。 基于从照射样品散射的辐射获得拉曼数据集。 根据拉曼数据集搜索数据库，以便从数据库中识别已知的拉曼数据集。 数据库包含多个已知的拉曼数据集，其中每个已知的拉曼数据集与相应的已知微生物的已知无形形式相关联。 基于通过搜索识别的已知拉曼数据集来鉴定样品微生物的固定形式。

公开(公告)号：US20070002319A1

公开(公告)日：2007-01-04

申请号：US11475582

申请日：2006-06-27

Applicant: Kevin Knopp ,  Peidong Wang ,  Masud Azimi ,  Daryoosh Vakhshoori

Inventor： Kevin Knopp ,  Peidong Wang ,  Masud Azimi ,  Daryoosh Vakhshoori

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0232 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/44 ,  G01J2003/1213 ,  G01N21/65 ,  G01N2021/656

Abstract: A Raman probe assembly for analyzing a specimen, comprising: a light source for generating laser excitation light; a camera for capturing an image; a light analyzer for analyzing a Raman signature; and a light path for (i) delivering the laser excitation light from the light source to the specimen so as to produce the Raman signature for the specimen, (ii) capturing an image of the specimen and directing that image to the camera, and (iii) directing the Raman signature of the specimen to the light analyzer. A Raman probe assembly for analyzing a specimen, comprising: a light source for generating laser excitation light; a camera for capturing an image; a light analyzer for analyzing a Raman signature; a first light path for delivering the laser excitation light from the light source to the specimen so as to produce the Raman signature for the specimen; a second light path for capturing an image of the specimen and directing that image to the camera; a third light path for directing the Raman signature of the specimen to the light analyzer; wherein the a least a portion of the first light path, the second light path and the third light path are coaxial with one another. A Raman probe assembly for analyzing a specimen, comprising: a light source for generating laser excitation light; a light analyzer for analyzing a Raman signature; a light path for (i) delivering the laser excitation light from the light source to the specimen so as to produce the Raman signature for the specimen, and (ii) directing the Raman signature of the specimen to the light analyzer; wherein the assembly further comprises a probe body for housing the at least a portion of the light path, and a window, with the light path extending through the window; and further wherein the probe body further comprises a shutter/wiper disposed adjacent to the window. A Raman probe assembly for analyzing a specimen, comprising: a light source for generating laser excitation light; a light analyzer for analyzing a Raman signature; a light path for (i) delivering the laser excitation light from the light source to the specimen so as to produce the Raman signature for the specimen, and (ii) directing the Raman signature of the specimen to the light analyzer; and wherein the light analyzer comprises a transmitter for transmitting information using an Internet Web protocol. A method for identifying the nature of a specimen, the method comprising: providing a Raman probe assembly comprising: a light source for generating laser excitation light; a camera for capturing an image; a light analyzer for analyzing a Raman signature; a light path for (i) delivering the laser excitation light from the light source to the specimen so as to produce the Raman signature for the specimen, (ii) capturing an image of the specimen and directing that image to the camera, and (iii) directing the Raman signature of the specimen to the light analyzer wherein the assembly further comprises a probe body for housing the at least a portion of the light path, and a window, with the light path extending through the window; wherein the probe body further comprises a shutter/wiper disposed adjacent to the window; wherein the assembly is carried by a remote controlled robot; providing a base station for receiving the image, and for remotely controlling the robot, and for receiving information from the light analyzer; navigating the remote control robot from the base station to a position adjacent to the specimen; opening the shutter/wiper; using the camera to aim the probe body at the specimen; energizing the light source so that the laser excitation light is directed at the specimen; and analyzing the return light passed to the light analyzer so as to determine of the nature of the specimen.

公开(公告)号：US20060262300A1

公开(公告)日：2006-11-23

申请号：US11131129

申请日：2005-05-17

Applicant: Vytas Gylys ,  David Stelman

Inventor： Vytas Gylys ,  David Stelman

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0227 ,  G01N21/65 ,  G01N21/8507

Abstract: A real time in situ system and method for monitoring solutions, such as basic hydrogen peroxide (BHP) and other laser fuel solutions, is provided. Raman spectroscopy is applied to a solution of interest to provide substantially real time and in situ characterization of the solution. In one embodiment, OOH− and H2O2 Raman peaks are monitored in real time and in situ for determination of BHP composition.

Abstract translation: 提供了实时原位系统和监测方法，如碱性过氧化氢（BHP）等激光燃料解决方案。 将拉曼光谱法应用于感兴趣的解决方案，以提供基本实时和原位表征的解决方案。 在一个实施方案中，实时和原位监测OOH和H 2 O 2 N 2拉曼峰以测定BHP组成。

公开(公告)号：US06813019B2

公开(公告)日：2004-11-02

申请号：US09958458

申请日：2001-10-05

Applicant: Michael R. Hammer ,  Philip V. Wilson ,  Mark R. Williams ,  Dower C. Bricker ,  Martin K. Masters ,  Stewart R. Campbell ,  Peter G. Layton

Inventor： Michael R. Hammer ,  Philip V. Wilson ,  Mark R. Williams ,  Dower C. Bricker ,  Martin K. Masters ,  Stewart R. Campbell ,  Peter G. Layton

IPC: G01J328

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/1809 ,  G01J3/2803 ,  G01J5/62 ,  G01J2003/1828 ,  G01N21/27 ,  G01N21/31

Abstract: A method and apparatus for the spectrochemical analysis of a sample in which a solid state array detector (82) is used to detect radiation (62) of spectrochemical interest. The invention involves the use of a shutter (72) adjacent the entrance aperture (70) of a polychromator (74-80) to expose the detector (82) to the radiation (62) for varying lengths of time whereby for short duration exposure times charge accumulation in elements (i.e. pixels) of the detector (82) due to high intensity components of the radiation is limited and for longer exposure times charge accumulation in elements (pixels) of the detector (82) due to feeble intesity components of radiation (62) is increased. This ensures that each reading of the detector (82) includes at least one exposure in which the amount of charge accumulated at each wavelength of interest is neither too little or too great. The problems of feeble radiation components not being accurately measurable and of high intensity radiation components exceeding the charge carrying capacity of elements (pixels) of the detector (82) are thereby able to be avoided. An attenuator (90) may be placed between the radiation source (60) and the detector (82) to permit longer exposure times to be used for very high intensity radiation.

Abstract translation: 用于对样品进行光谱化学分析的方法和装置，其中固态阵列检测器（82）用于检测分光光度的辐射（62）。 本发明涉及使用与多色调剂（74-80）的入口孔（70）相邻的快门（72）将检测器（82）暴露于辐射（62）以改变长度的时间，从而短时间曝光时间 由于辐射的高强度分量，检测器（82）的元件（即，像素）中的电荷累积受到限制，并且由于辐射的微弱的肥胖分量，对于更长的曝光时间来检测器（82）的元件（像素）中的电荷累积 62）增加。 这确保了检测器（82）的每次读取包括至少一次曝光，其中在每个感兴趣波长处累积的电荷量既不太小也不太大。 因此能够避免无法精确测量的微弱辐射成分和超过检测器（82）的元件（像素）的电荷承载能力的高强度辐射成分的问题。 衰减器（90）可以放置在辐射源（60）和检测器（82）之间，以允许更长的曝光时间用于非常高强度的辐射。

公开(公告)号：US06753966B2

公开(公告)日：2004-06-22

申请号：US09803131

申请日：2001-03-09

Applicant: Charles W. Von Rosenberg

Inventor： Charles W. Von Rosenberg

IPC: G01N2100

CPC classification number: G01J3/02 ,  G01J3/0213 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0232 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/28 ,  G01J3/502 ,  G01J2003/2866 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G01N21/8507 ,  G01N33/10

Abstract: The present invention relates to spectral analysis systems and methods for determining physical and chemical properties of a sample by measuring the optical characteristics of light emitted from the sample. In one embodiment, a probe head for use with a spectrometer includes a reflector for illuminating a sample volume disposed circumferentially about the light source of the probe head. In another embodiment, a probe head includes an optical blocking element for forcing the optical path between the light source and an optical pick-up optically connected to the spectrometer into the sample. The probe head also includes a reference shutter for selectively blocking light emitted from the sample from reaching the optical pick-up to facilitate calibration of the spectrometer.

Abstract translation: 本发明涉及通过测量从样品发射的光的光学特性来确定样品的物理和化学性质的光谱分析系统和方法。 在一个实施例中，用于光谱仪的探针头包括用于照亮围绕探头的光源周向设置的样品体积的反射器。 在另一个实施例中，探头包括用于迫使光源和光学连接到光谱仪的光学拾取器之间的光路进入样品的光学阻挡元件。 探头还包括用于选择性地阻挡从样品发射的光到达光学拾波器以便于校准光谱仪的参考快门。