公开(公告)号：US20160135803A1

公开(公告)日：2016-05-19

申请号：US14880894

申请日：2015-10-12

Applicant: Abbott Laboratories

Inventor： Scott A. McIntosh

IPC: A61B17/04

CPC classification number: A61B17/0469 ,  A61B17/0491 ,  A61B17/122 ,  A61B90/39 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00615 ,  A61B2017/0472 ,  A61B2017/0475 ,  A61B2017/0477

Abstract: In accordance with the present invention there is provided a suturing device. The suturing device includes a length of suture that will be delivered to the site of the PFO and placed through the tissue adjacent the opening to close the PFO. As described in greater detail below, the suture is advanced through the tissue surrounding the opening by a pair of needles that penetrate the tissue adjacent to the opening. A knot is then loosely tied with the length of suture and advanced to the site of the PFO. The tails of the suture extending from the knot are then cut and removed. It is also contemplated that a pre-formed or pre-tied knot may be disposed on the device, wherein after deployment of the suture through the tissue adjacent to the PFO and removal of the device a loop of suture having a pre-tied knot will remain, wherein the pre-tied knot may then be tightened to close the PFO. Further still it is contemplated that other means may be utilized to retain the sutures. For example, it is contemplated that a suture clip or other clip like device may be utilized to retain the suture in a position such that the PFO is closed.

公开(公告)号：US20160116427A1

公开(公告)日：2016-04-28

申请号：US14920222

申请日：2015-10-22

Applicant: Abbott Laboratories

Inventor： Sophie Laurenson

IPC: G01N27/327 ,  B05D7/00 ,  B05D5/00

CPC classification number: G01N27/3275 ,  B01L3/502707 ,  B01L2200/141 ,  B01L2200/142 ,  B01L2300/022 ,  B01L2300/023 ,  B01L2300/024 ,  B01L2300/0645 ,  B01L2300/089 ,  B01L2300/126 ,  B01L2300/161 ,  B05D5/00 ,  B05D7/58 ,  G01N27/327

Abstract: Example paper substrate diagnostic apparatus and related methods and systems are disclosed herein. An example apparatus includes a hydrophobic substrate having a first end and a second end opposite the first end. The apparatus includes a detection zone on a first surface of the substrate, the detection zone defining an area to sense an analyte in a sample, the detection zone comprising a first electrode and a second electrode disposed on the first surface of the substrate and a layer of hydrophilic ink disposed on the two electrodes and an area between the first and second electrodes. The apparatus also includes a channel comprising hydrophilic ink disposed on the first surface of the substrate, the channel having an inlet section adjacent the first end of the substrate, a middle section, and an outlet section in contact with the layer of hydrophilic ink. The channel is to transfer a fluid sample from the inlet section to the layer of hydrophilic ink.

Abstract translation: 本文公开了纸基板诊断装置及相关方法和系统。 示例性设备包括具有第一端和与第一端相对的第二端的疏水性衬底。 所述设备包括在所述基板的第一表面上的检测区域，所述检测区域限定用于感测样品中的分析物的区域，所述检测区域包括设置在所述基板的第一表面上的第一电极和第二电极， 设置在两个电极上的亲水性墨水和第一和第二电极之间的区域。 该设备还包括一个通道，该通道包括设置在基板的第一表面上的亲水性油墨，该通道具有邻近基板的第一端的入口部分，中间部分和与该亲水墨水层接触的出口部分。 通道是将流体样品从入口部分转移到亲水性油墨层。

公开(公告)号：US20160106131A1

公开(公告)日：2016-04-21

申请号：US14982488

申请日：2015-12-29

Applicant: ABBOTT LABORATORIES

Inventor： Menghua LUO ,  Jeffrey NELSON ,  Anne VOSS ,  Owen KELLY ,  Geraldine BAGGS ,  Min TIAN ,  Jamie PARTRIDGE

IPC: A23L1/305 ,  A61K31/19

CPC classification number: A61K31/19 ,  A23L33/175 ,  A23L33/30 ,  A23L33/40 ,  A23V2002/00 ,  A23V2200/322 ,  A23V2200/30

Abstract: A method of care is described that includes administering an effective amount of β-hydroxy-β-methylbutyrate (HMB) to an adult or elderly patient to improve the patient's quality of life during or after hospitalization of the patient. The improved quality of life may encompass the general health, physical health, or mental health of the patient.

Abstract translation: 描述了一种护理方法，其包括向成人或老年患者施用有效量的β-羟基 - 甲基丁酸酯（HMB），以改善患者在住院期间或之后的患者生活质量。 改善的生活质量可能包括患者的一般健康，身体健康或精神健康。

公开(公告)号：US20160100967A1

公开(公告)日：2016-04-14

申请号：US14968707

申请日：2015-12-14

Applicant: Abbott Laboratories

Inventor： Randolf Von Oepen ,  John L. Toner

IPC: A61F2/958 ,  A61L31/08

CPC classification number: A61F2/958 ,  A61F2002/9583 ,  A61L29/085 ,  A61L29/14 ,  A61L31/08 ,  A61L31/10 ,  A61L31/14

Abstract: A method for improving the retention between the surfaces of medical devices. The method includes coating a surface of one medical device such as a stent with a coating that includes a functional group and coating a surface of another medical device such as a balloon with a coating that includes an identical or different functional group. The method further includes interacting the coated surfaces to produce a plurality of bonds between the surfaces, thereby improving retention.

Abstract translation: 一种用于改善医疗装置表面之间的保持性的方法。 该方法包括用包括官能团的涂层涂覆诸如支架的一个医疗装置的表面，并用包括相同或不同官能团的涂层涂覆其它医疗装置例如气囊的表面。 该方法还包括相互作用涂覆的表面以在表面之间产生多个键，从而改善保留。

公开(公告)号：US09308560B2

公开(公告)日：2016-04-12

申请号：US14306961

申请日：2014-06-17

Applicant: Abbott Laboratories

Inventor： Patricia H. Ravalico ,  Charlie W. Wilson, III

IPC: B08B3/04 ,  G01N35/10 ,  B08B3/02

CPC classification number: G01N35/1004 ,  B08B3/02 ,  B08B3/04 ,  G01N35/10 ,  G01N35/1016 ,  G01N2035/00277 ,  G01N2035/1006 ,  Y10T436/114998 ,  Y10T436/115831 ,  Y10T436/12

Abstract: A clinical analyzer has been described that includes a probe to aspirate a fluid. The probe is washed between aspirations to reduce carryover. The wash operation includes both an internal and an external wash, where the internal wash operation is terminated prior to terminating the external wash. In one example, the probe wash can be implemented on an integrated clinical chemistry/immunoassay analyzer.

Abstract translation: 已经描述了包括用于吸入流体的探针的临床分析仪。 探针在欲望之间洗涤以减少携带。 洗涤操作包括内部和外部洗涤，其中内部洗涤操作在终止外部洗涤之前终止。 在一个示例中，探针洗涤可以在综合的临床化学/免疫测定分析仪上实现。

公开(公告)号：US20160066610A1

公开(公告)日：2016-03-10

申请号：US14888314

申请日：2014-05-01

Applicant: ABBOTT LABORATORIES

Inventor： SEAN GARVEY ,  SUZETTE PEREIRA ,  NEILE EDENS

IPC: A23L1/30 ,  A61K31/19 ,  A61K31/353 ,  A23L1/305 ,  A23L1/29

CPC classification number: A23L33/105 ,  A23L33/15 ,  A23L33/17 ,  A23L33/175 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/19 ,  A61K31/353 ,  A23V2200/316 ,  A61K2300/00

Abstract: Compositions and methods for enhancing the regenerative capacity of an individual are provided. The compositions include, and the methods provide, a combination of an effective amount of epigallocatechin-3-gallate (EGCg) and an effective amount of beta-hydroxy-beta-methylbutyrate (HMB) to decrease the level of intramuscular FGF2, to enhance the regenerative capacity of muscle, or both.

Abstract translation: 提供了增强个人再生能力的组合物和方法。 组合物包括并且该方法提供有效量的表没食子儿茶-3-没食子酸酯（EGCg）和有效量的β-羟基-β-甲基丁酸酯（HMB）的组合以降低肌内FGF2的水平，以增强 肌肉的再生能力，或两者。

公开(公告)号：US09261523B2

公开(公告)日：2016-02-16

申请号：US14152779

申请日：2014-01-10

Applicant: Abbott Laboratories

Inventor： Patrick P. Fritchie ,  John C. Jones ,  Oscar F. Schwartz

IPC: G01N35/00 ,  G06Q10/08 ,  G06Q10/00

CPC classification number: G01N35/00663 ,  G01N35/00584 ,  G01N35/00732 ,  G01N35/0099 ,  G01N35/04 ,  G01N2035/00435 ,  G01N2035/00673 ,  G01N2035/00762 ,  G01N2035/00811 ,  G01N2035/00821 ,  G01N2035/0091 ,  G06Q10/087 ,  Y10T436/11 ,  Y10T436/13

Abstract: A system for managing the inventory of reagents for a laboratory automation system. The system for managing the inventory of reagents comprises a controller, software for the controller, and a refrigerator capable of refrigerating reagents, detecting the presence or absence of reagents in the refrigerator, and detecting the location of reagents in the refrigerator. The system for managing the inventory of reagents is connected to a laboratory automation system. The laboratory automation system comprises at least one clinical analyzer. A typical system for managing inventories of reagents includes an operator interface for the loading of boxes of reagents and other supplies, radio frequency identification system for identification of inventory and tracking, robotic mechanisms for loading containers onto the track system and removing containers from the track system, de-capping equipment, refrigeration equipment, and information technology connections to laboratory analyzers and vendors.

Abstract translation: 用于管理实验室自动化系统试剂库存的系统。 用于管理试剂库存的系统包括控制器，用于控制器的软件和能够冷藏试剂的冰箱，检测冰箱中试剂的存在或不存在以及检测冰箱中试剂的位置。 用于管理试剂库存的系统连接到实验室自动化系统。 实验室自动化系统至少包括一个临床分析仪。 用于管理试剂库存的典型系统包括用于装载试剂盒和其他用品的操作者界面，用于识别库存和跟踪的射频识别系统，用于将容器装载到轨道系统上的机器人机构以及从轨道系统中移出容器 ，脱帽设备，制冷设备以及与实验室分析仪和供应商的信息技术连接。

公开(公告)号：US09255341B2

公开(公告)日：2016-02-09

申请号：US14135279

申请日：2013-12-19

Applicant: Abbott Laboratories Vascular Enterprises Limited

Inventor： Elena Wulf

IPC: C25F3/16 ,  C25F7/00 ,  A61L31/14

CPC classification number: C25F3/16 ,  A61L31/14 ,  A61L2400/18 ,  C25F7/00

Abstract: An apparatus, a method, and an electrolytic solution are described for electropolishing metallic stents made, for example, of high-strength medical alloys. The apparatus may include an electropolishing container made from material of low thermal conductivity. The apparatus may include at least one spiral cathode for optimization of solution agitation and/or voltage distribution in the electrolytic solution. Further, an electrolytic solution including at least dimethylsulfate is described. A method for improved electropolishing to consistently produce smooth surfaces is also described.

Abstract translation: 描述了用于电抛光例如由高强度医用合金制成的金属支架的装置，方法和电解液。 该装置可以包括由导热性低的材料制成的电解抛光容器。 该装置可以包括用于优化电解溶液中的溶液搅拌和/或电压分布的至少一个螺旋阴极。 此外，描述至少包含硫酸二甲酯的电解液。 还描述了用于改进电解抛光以一致地产生光滑表面的方法。

公开(公告)号：US20160022710A1

公开(公告)日：2016-01-28

申请号：US14774745

申请日：2014-03-13

Applicant: ABBOTT LABORATORIES

Inventor： Chron-Si Lai ,  Tama Bloch ,  Christina Sherry ,  Maria Ramirez Gonzalez ,  Matthew Kuchan ,  Gary Katz ,  Elena Oliveros Delgado ,  Angela Santos

IPC: A61K31/685 ,  A61K31/202 ,  A61K31/047 ,  A23L1/29 ,  A61K31/015 ,  A61K31/045 ,  A61K9/48 ,  A61K31/355 ,  A61K31/593

CPC classification number: A61K31/685 ,  A23L33/10 ,  A23L33/115 ,  A23L33/12 ,  A23L33/13 ,  A23L33/15 ,  A23L33/155 ,  A23L33/40 ,  A23V2002/00 ,  A61K9/48 ,  A61K9/4808 ,  A61K31/015 ,  A61K31/045 ,  A61K31/047 ,  A61K31/065 ,  A61K31/202 ,  A61K31/355 ,  A61K31/593 ,  A61K2300/00

Abstract: Disclosed are prenatal and lactation supplements for pregnant women and lactating women, which include a combination of RRR-alpha-tocopherol, docosahexaenoic acid (DHA), trans-lutein, phospholipids, and at least one nuclear receptor activating ligand other than RRR-alpha-tocopherol, DHA, and trans-lutein. The supplements may enhance central nervous system development in a fetus or breast-feeding newborn infant.

Abstract translation: 公开了孕妇和哺乳期妇女的产前和哺乳期补品，其中包括RRR-α-生育酚，二十二碳六烯酸（DHA），反式叶黄素，磷脂以及除RRR-α-生育酚之外的至少一种核受体活化配体的组合， 生育酚，DHA和反式叶黄素。 补充剂可以增强胎儿或母乳喂养新生儿的中枢神经系统发育。

公开(公告)号：US20160018311A1

公开(公告)日：2016-01-21

申请号：US14808211

申请日：2015-07-24

Applicant: Abbott Laboratories

Inventor： Jiong Wu ,  Michael R. Buhl ,  Giacomo Vacca

IPC: G01N15/14 ,  G01N33/49 ,  G01N21/64

CPC classification number: G01N15/1434 ,  G01N15/1459 ,  G01N21/6428 ,  G01N33/49 ,  G01N2015/0069 ,  G01N2015/008 ,  G01N2015/1006 ,  G01N2015/1402 ,  G01N2015/1477 ,  G01N2015/1486 ,  G01N2015/1488 ,  G01N2021/6439

Abstract: Provided herein are systems and methods for analyzing blood samples, and more specifically for performing a basophil analysis. In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye; and then (b) using measurements of light scatter and fluorescence emission to distinguish basophils from other WBC sub-populations. In one embodiment, the systems and methods include performing a basophil cluster analysis of the blood sample, based on the combination of light scatter and fluorescence measurements.

Abstract translation: 本文提供了用于分析血液样品的系统和方法，并且更具体地用于进行嗜碱性粒细胞分析。 在一个实施方案中，系统和方法包括：（a）用专用细胞膜可渗透荧光染料染色血液样品; 然后（b）使用光散射和荧光发射的测量来区分嗜碱性粒细胞与其他WBC亚种群。 在一个实施方案中，系统和方法包括基于光散射和荧光测量的组合进行血液样品的嗜碱性粒细胞聚类分析。