公开(公告)号：US20120276287A1

公开(公告)日：2012-11-01

申请号：US13545445

申请日：2012-07-10

Applicant: Katsumi SHIBAYAMA ,  Helmut Teichmann ,  Tomofumi Suzuki ,  Dietmar Hiller ,  Ulrich Starker

Inventor： Katsumi SHIBAYAMA ,  Helmut Teichmann ,  Tomofumi Suzuki ,  Dietmar Hiller ,  Ulrich Starker

IPC: B05D5/06

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/0243 ,  G01J3/0259 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/04 ,  G01J3/2803

Abstract: In the spectroscopy module 1, a light detecting element 4 is provided with a light passing opening 4b through which light made incident into a body portion 2 passes. Therefore, it is possible to prevent deviation of the relative positional relationship between the light passing opening 4b and a light detection portion 4a of the light detecting element 4. Further, an optical element 7, which guides light made incident into the body portion 2, is arranged at the light passing opening 4b. Therefore, light, which is to be made incident into the body portion 2, is not partially blocked at a light incident edge portion of the light passing opening 4b, but light, which is to be made incident into the body portion 2, can be guided securely. Therefore, according to the spectroscopy module 1, it is possible to improve the reliability.

Abstract translation: 在光谱模块1中，光检测元件4设置有入射到主体部分2中的光通过的光通过开口4b。 因此，能够防止光通过口4b与光检测元件4的光检测部4a之间的相对位置关系的偏差。此外，引导入射到主体部2的光的光学元件7， 布置在光通过开口4b处。 因此，入射到主体部分2中的光在光通过开口4b的光入射边缘部分处不被部分地阻挡，而入射到主体部分2中的光可以是 引导安全。 因此，根据光谱模块1，可以提高可靠性。

公开(公告)号：US08300220B2

公开(公告)日：2012-10-30

申请号：US12713071

申请日：2010-02-25

Applicant: Anita M. Mahadevan-Jansen ,  David Dickensheets ,  Chad Lieber

Inventor： Anita M. Mahadevan-Jansen ,  David Dickensheets ,  Chad Lieber

IPC: G01J3/44

CPC classification number: G01J3/44 ,  A61B5/0059 ,  A61B5/0064 ,  A61B5/0068 ,  A61B5/0075 ,  A61B5/444 ,  A61B5/445 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0237 ,  G01J3/4412 ,  G01N21/65 ,  G01N2021/656

Abstract: A probe using integrated confocal reflectance imaging, confocal Raman spectroscopy, and gross spatial imaging for non-invasiveIy evaluating a target of interest of a living subject. In one embodiment, the probe includes a casing with first and second ends, and first, second and third optical pons The firsi and second optical ports are located at the first end of the casing and the third optical port is located at the second end of the casing such that the first and third optical ports define a first optical path therebetween and the second and third optical ports define a second optical path therebetween, respectively. Each optical path has first and second portions, where the second portions of the first and second optical paths arc substantially overlapped and proximal to the third optical port.

Abstract translation: 使用集成共聚焦反射成像，共焦拉曼光谱和非侵入性的总体空间成像的探针，用于评估活体感兴趣的目标。 在一个实施例中，探针包括具有第一和第二端以及第一，第二和第三光学臂的壳体，所述第二光学端口位于壳体的第一端，并且第三光学端口位于壳体的第二端 所述壳体使得所述第一和第三光学端口在其间限定第一光路，并且所述第二和第三光学端口分别在其间限定第二光路。 每个光路具有第一和第二部分，其中第一和第二光路的第二部分基本上重叠并且靠近第三光学端口。

公开(公告)号：US08299584B2

公开(公告)日：2012-10-30

申请号：US12719241

申请日：2010-03-08

Applicant: Dmitriy Shneyder ,  Srinivasan Rangarajan ,  Michael J. Shapiro ,  Anthony K. Stamper ,  Huilong Zhu

Inventor： Dmitriy Shneyder ,  Srinivasan Rangarajan ,  Michael J. Shapiro ,  Anthony K. Stamper ,  Huilong Zhu

IPC: H01L23/48

CPC classification number: B32B38/00 ,  G01B11/27 ,  G01J3/02 ,  G06F15/00 ,  H01L23/48 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A method of aligning substrates, e.g., semiconductor wafers, is provided in which a first substrate can be at least coarsely aligned atop a second substrate. Each substrate can have a pattern thereon, wherein the pattern of the first substrate can be aligned with a window of the first substrate. A return signal can be returned from simultaneously illuminating the patterns of the first and second substrates through the window in the first substrate. The return signal can be compared to at least one stored signal to determine relative misalignment between the first and second substrates. A position of at least one of the first and second substrates can be altered relative to a position of the other of the first and second substrates to address the misalignment.

Abstract translation: 提供了对准例如半导体晶片的衬底的方法，其中第一衬底可以至少在第二衬底的顶部上对齐。 每个衬底可以具有其上的图案，其中第一衬底的图案可以与第一衬底的窗口对准。 可以通过第一衬底中的窗口同时照亮第一和第二衬底的图案来返回返回信号。 可以将返回信号与至少一个存储的信号进行比较，以确定第一和第二基板之间的相对不对准。 可以相对于第一和第二基板中的另一个的位置改变第一和第二基板中的至少一个的位置，以解决未对准。

公开(公告)号：US20120268737A1

公开(公告)日：2012-10-25

申请号：US13541883

申请日：2012-07-05

Applicant: Victor Mazzio

Inventor： Victor Mazzio

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/4412

Abstract: An improved Raman microspectrometer system extends the optical reach and analysis range of an existing Raman microspectrometer to allow analysis and/or repair of an oversized sample. The improved Raman microspectrometer system includes an extender for extending the optical reach of the existing microspectrometer and a supplemental stage which extends the analysis range of the existing microspectrometer by providing travel capabilities for non-destructive analysis of an entire oversized sample. Such an arrangement decreases manufacturing costs associated with testing oversized samples such as mammography panels, enabling analysis and/or repair to be performed without destruction.

Abstract translation: 改进的拉曼显微光谱仪系统扩展了现有拉曼显微光谱仪的光学范围和分析范围，以便对超大样品进行分析和/或修复。 改进的拉曼显微光谱仪系统包括扩展器，用于扩展现有显微光度计的光学范围，以及补充级，通过提供用于整个超大样本的非破坏性分析的行进能力来扩展现有微光谱仪的分析范围。 这样的布置降低了与测试超大样本（例如乳房X线照相面板）相关联的制造成本，使得能够进行分解和/或修复而不破坏。

公开(公告)号：US20120268730A1

公开(公告)日：2012-10-25

申请号：US13540109

申请日：2012-07-02

Applicant: Michael L. Myrick ,  Robert P. Freese ,  William Soltmann ,  David L. Perkins

Inventor： Michael L. Myrick ,  Robert P. Freese ,  William Soltmann ,  David L. Perkins

IPC: G01N21/00

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0232 ,  G01J3/0235 ,  G01J3/0243 ,  G01J3/0286 ,  G01J3/08 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/1213 ,  G01N2201/1293

Abstract: The present subject matter relates to an apparatus and related method of high-speed analysis of product samples during production of the product. Light is directed to a portion of a product under analysis and reflected from or transmitted through the product toward optical detectors. Signals from the optical detectors are compared to determine characteristics of the product under analysis. Temperature within the monitoring system may be monitored in order to provide compensation for the signals produced by the optical detectors. The products under analysis may be stationary, moved by an inspection point by conveyor or other means, or may be contained within a container, the container including a window portion through which the product illuminating light may pass.

Abstract translation: 本发明涉及在产品生产过程中产品样品的高速分析的装置和相关方法。 光被引导到被分析产品的一部分，从产品反射或透射到光学检测器。 将来自光学检测器的信号进行比较，以确定正在分析的产品的特性。 可以监视监视系统内的温度，以便为由光学检测器产生的信号提供补偿。 被分析的产品可以是固定的，由检查点通过输送机或其他方式移动，或者可以容纳在容器内，该容器包括产品照明光通过的窗口部分。

公开(公告)号：US08294990B2

公开(公告)日：2012-10-23

申请号：US12554240

申请日：2009-09-04

Applicant: Douglas J. Brown ,  Daniel B. Mitchell ,  Geoffrey G. Harris

Inventor： Douglas J. Brown ,  Daniel B. Mitchell ,  Geoffrey G. Harris

IPC: G02B27/00 ,  G02B5/28

CPC classification number: G02B26/00 ,  G01J3/02 ,  G01J3/0262 ,  G01J3/06 ,  G01J3/12 ,  G01J2003/1213 ,  G01J2003/1243 ,  G01J2003/1247 ,  G02B5/28 ,  G02B21/16 ,  G02B26/007

Abstract: An apparatus includes an optical filter having first and second passbands that are different, the optical filter including selectively operable first passband adjusting structure that varies a characteristic of the first passband without influencing the second passband. According to a different aspect, a method includes filtering radiation with an optical filter having first and second passbands that are different, and selectively varying a characteristic of the first passband without influencing the second passband.

Abstract translation: 一种装置包括具有不同的第一和第二通带的滤光器，所述滤光器包括可选择地操作的第一通带调整结构，其改变第一通带的特性而不影响第二通带。 根据不同方面，一种方法包括利用具有不同的第一和第二通带的滤光器来过滤辐射，并且选择性地改变第一通带的特性而不影响第二通带。

公开(公告)号：US20120262713A1

公开(公告)日：2012-10-18

申请号：US13518797

申请日：2010-12-13

Applicant: Stefan Florek ,  Michael Okruss ,  Helmut Becker-Ross

Inventor： Stefan Florek ,  Michael Okruss ,  Helmut Becker-Ross

IPC: G01J3/42

CPC classification number: G01J3/1809 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0235 ,  G01J3/14 ,  G01J3/2803 ,  G01J2003/1828

Abstract: A spectrometer assembly (10), comprising an Echelle grating (18; 46) for dispersing radiation entering the spectrometer assembly (10) in a main dispersion direction, and a dispersion assembly (16; 40) for dispersing a parallel radiation bundle generated from the radiation entering the spectrometer assembly in a lateral dispersion direction, is characterized in that the dispersion assembly (16; 40) is reflective, and the dispersion assembly (16; 40) is arranged relative to the Echelle grating (18; 46) in such a way that the parallel radiation bundle is reflected in the direction of the Echelle grating. The Echelle grating (18; 46) may be arranged in such a way that the dispersed radiation is reflected back to the dispersion assembly (16; 40).

Abstract translation: 一种光谱仪组件（10），包括用于分散在主分散方向上进入光谱仪组件（10）的辐射的梯形光栅（18; 46）和用于分散从所述分散体组件（10; 40）产生的平行辐射束 辐射进入光谱仪组件的横向分散方向，其特征在于分散体组件（16; 40）是反射性的，分散体组件（16; 40）相对于Echelle光栅（18; 46） 平行辐射束在Echelle光栅的方向上反射的方式。 可以将梯形光栅（18; 46）布置成使得分散的辐射被反射回到分散体组件（16; 40）。

公开(公告)号：US20120259228A1

公开(公告)日：2012-10-11

申请号：US13464578

申请日：2012-05-04

Applicant: Chung-Chieh Yu ,  Condon Lau ,  Stephen Fulghum ,  Christopher Fang-yen ,  Ramachandra Dasari ,  Michael Feld ,  David Feld ,  Alison Hearn ,  Jonathan Feld

Inventor： Chung-Chieh Yu ,  Condon Lau ,  Stephen Fulghum ,  Christopher Fang-yen ,  Ramachandra Dasari ,  Michael Feld ,  David Feld ,  Alison Hearn ,  Jonathan Feld

IPC: A61B6/00 ,  A61B18/20

CPC classification number: A61B5/0059 ,  A61B5/0066 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/0229 ,  G01J3/10 ,  G01J3/32 ,  G01N21/4738 ,  G01N21/49 ,  G01N2021/4733

Abstract: The present invention relates to a spectroscopic imaging system using autofluorescence and reflectance images to diagnose tissue. A preferred embodiment of the invention uses a plurality of light sources to illuminate a tissue region to provide the fluorescence and reflectance images, respectively.

Abstract translation: 本发明涉及使用自发荧光和反射图像诊断组织的光谱成像系统。 本发明的优选实施例使用多个光源照射组织区域以分别提供荧光和反射图像。

公开(公告)号：US08274725B2

公开(公告)日：2012-09-25

申请号：US12880818

申请日：2010-09-13

Applicant: Andrew Bodkin

Inventor： Andrew Bodkin

IPC: G02B26/02

CPC classification number: G02B26/02 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/027 ,  G01J3/0278 ,  G01J3/0289 ,  G01J3/36 ,  G01J5/06 ,  G01J5/602 ,  G01J2005/0077 ,  G01S7/4812 ,  G01S17/87 ,  G01S17/89 ,  G02B3/0006 ,  G02B17/0808 ,  G02B17/0852 ,  G02B17/0896 ,  G02B23/12 ,  G02B26/0816 ,  G02B26/0875 ,  H04N5/33 ,  H04N5/332

Abstract: A shutter includes micro-optics having first and second concentrator arrays. A transducer laterally displaces one of the first and second concentrator arrays between transmissive and shuttered modes. In the transmissive mode, the arrays of concentrators are optically aligned to permit electromagnetic energy passing through the first array of concentrators to pass through the second array of concentrators. In the shuttered mode, the electromagnetic radiation is blocked from passing through the second array of concentrators. The concentrators may be compound parabolic concentrators, or lenslets positioned on opposing plates with pinholes printed therethrough. The shutter may increase f-number of radiation passing therethrough, and may be used in a limited f-cone radiation source with shuttering abilities, for example reducing f-cone of radiation output from the radiation source.

Abstract translation: 快门包括具有第一和第二聚光器阵列的微光学器件。 换能器在透射和快门模式之间横向移位第一和第二聚光器阵列中的一个。 在透射模式中，聚光器阵列被光学对准以允许通过第一集中器阵列的电磁能量穿过第二阵列的聚光器。 在快门模式中，电磁辐射被阻止通过第二阵列的聚光器。 集中器可以是复合抛物面聚光器，或者位于相对的板上的小透镜，其中针孔印刷在其中。 快门可以增加通过其中的f数量的辐射，并且可以用于具有快门能力的有限的f-锥体辐射源，例如减小从辐射源输出的辐射的f锥。

公开(公告)号：US08269174B2

公开(公告)日：2012-09-18

申请号：US12719904

申请日：2010-03-09

Applicant: Charles W. Gardner ,  Patrick J. Treado ,  Matthew Nelson ,  Robert Schweitzer

Inventor： Charles W. Gardner ,  Patrick J. Treado ,  Matthew Nelson ,  Robert Schweitzer

IPC: G01J5/02

CPC classification number: G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/44 ,  G01N21/31 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/65

Abstract: A method and a portable device for assessing the occurrence of an agent in a sample. A sample is illuminated with photons emanating from a portable device to produce photons reflected, emitted, or absorbed from a set of multiple points in the sample having a defined geometric relationship. The portable device is used to simultaneously illuminate the sample and analyze the photons reflected, emitted, or absorbed from the set of multiple points using spectroscopic methods, including infrared, fluorescence, and UV/visible. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof.

Abstract translation: 一种用于评估样品中的试剂的发生的方法和便携式装置。 用便携式设备发出的光子照射样品，以产生从具有确定的几何关系的样品中的一组多个点反射，发射或吸收的光子。 便携式设备用于同时照亮样品并使用包括红外，荧光和紫外/可见光在内的光谱方法分析从该组多个点反射，发射或吸收的光子。 所评估的试剂可以包括危险剂，化学试剂，生物制剂，微生物，细菌，原生动物，病毒及其组合。