公开(公告)号：US09329086B2

公开(公告)日：2016-05-03

申请号：US13905817

申请日：2013-05-30

Applicant: CHEMIMAGE TECHNOLOGIES LLC

Inventor： Patrick J. Treado ,  Ryan Priore

IPC: G01N21/00 ,  G01J3/51 ,  G01J3/457 ,  G01N21/25 ,  G01J3/02 ,  G01N21/33 ,  G01N21/359 ,  G01N21/65 ,  G01N21/71 ,  G01J3/12 ,  G01N21/64 ,  G01N21/35

CPC classification number: G01J3/51 ,  G01J3/0224 ,  G01J3/0272 ,  G01J3/457 ,  G01J2003/1213 ,  G01N21/255 ,  G01N21/33 ,  G01N21/35 ,  G01N21/359 ,  G01N21/65 ,  G01N21/718 ,  G01N2021/6471 ,  G01N2201/0221 ,  G01N2201/067 ,  G01N2201/129

Abstract: A portable system and method for analyzing biological tissue samples and detecting analytes associated with tissue oxygenation using a conformal filter. A conformal filter, which may comprise a tunable filter, is configured to filter interacted photons conforming to a spectral shape correlated with an analyte of interest. Conformal filter configurations may be selected by consulting a modified look-up table associated with an analyte. An iterative methodology may be used to calibrate a conformal design for an analyte of interest, refine a previous conformal filter design for an analyte of interest, and/or generate a new conformal filter design for an analyte of interest.

Abstract translation: 用于分析生物组织样品并使用保形过滤器检测与组织氧合相关的分析物的便携式系统和方法。 可以包括可调滤波器的保形滤波器被配置为滤波符合与感兴趣的分析物相关的光谱形状的相互作用的光子。 可以通过咨询与分析物相关联的经修改的查找表来选择保形过滤器配置。 可以使用迭代方法来校准感兴趣分析物的共形设计，改进目标分析物的先前共形过滤器设计，和/或为感兴趣的分析物生成新的保形过滤器设计。

公开(公告)号：US20160097678A1

公开(公告)日：2016-04-07

申请号：US14966896

申请日：2015-12-11

Applicant: ADOM, Advanced Optical Technologies Ltd.

Inventor： Yoel Arieli ,  Yosef Weitzman

IPC: G01J3/447 ,  G01J3/28 ,  G01J3/45

CPC classification number: G01J3/447 ,  G01B9/02 ,  G01B11/02 ,  G01J3/0224 ,  G01J3/027 ,  G01J3/12 ,  G01J3/2823 ,  G01J3/32 ,  G01J3/45 ,  G01J3/453 ,  G01N21/211 ,  G01N21/31 ,  G01N21/4795 ,  G02F1/13336

Abstract: There is provided a method for analyzing optical properties of an object, including utilizing a light illumination having a plurality of amplitudes, phases and polarizations of a plurality of wavelengths impinging from the object, obtaining modified illuminations corresponding to the light illumination, applying a modification to the light illumination thereby obtaining a modified light illumination, analyzing the modified light illumination, obtaining a plurality of amplitudes, phases and polarizations maps of the plurality of wavelengths, and employing the plurality of amplitudes, phases and polarizations maps for obtaining output representing the object's optical properties. An apparatus for analyzing optical properties of an object is also provided.

Abstract translation: 提供了一种用于分析物体的光学特性的方法，包括利用具有从物体入射的多个波长的多个振幅，相位和极化的光照，获得对应于光照射的修改照明，对 光照明，从而获得修改的光照明，分析修改的光照明，获得多个波长的多个振幅，相位和极化图，并采用多个幅度，相位和极化映射，以获得表示物体的光学 属性。 还提供了一种用于分析物体的光学特性的装置。

公开(公告)号：US20160076942A1

公开(公告)日：2016-03-17

申请号：US14121491

申请日：2014-09-11

Applicant: Mazen Zawaideh ,  Chris Claypool ,  Emad Zawaideh

Inventor： Mazen Zawaideh ,  Chris Claypool ,  Emad Zawaideh

IPC: G01J4/04 ,  G01J3/447 ,  G01J3/28

CPC classification number: G01J4/04 ,  A61B5/0075 ,  A61B5/725 ,  A61B5/7257 ,  G01J3/0224 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/447 ,  G01J2003/2826 ,  G01N2021/213

Abstract: An imaging spectropolarimeter for examining targets with polarized light, the spectropolarimeter including a light source adapted to produce polarized light directed at a target. Embodiments also include a three-camera camera system defining a three-camera camera axis with a first camera unit comprising a first analyzer set at 0°, a lens and a first multi-pixel sensor, a second camera unit comprising a second analyzer set at 45°, a lens and a second multi-pixel sensor, and a third camera unit comprising a third analyzer set at 90°, a lens and a third multi-pixel sensor. At least two beam splitters adapted to direct a portion of polarized light reflected from the target to each of the first, second and third camera units. Preferred systems include a processor adapted to produce polarimetric images of the target utilizing intensity information collected by the multi-pixel sensors.

Abstract translation: 用于用偏振光检查目标的成像分光偏振计，分光偏振计包括适于产生指向目标的偏振光的光源。 实施例还包括定义三相机相机轴的三相机相机系统，第一相机单元包括设置为0°的第一分析器，透镜和第一多像素传感器，第二相机单元，包括第二分析器 45°，透镜和第二多像素传感器，以及第三相机单元，包括设置在90°的第三分析器，透镜和第三多像素传感器。 至少两个分束器，其适于将从目标反射的偏振光的一部分引导到第一，第二和第三相机单元中的每一个。 优选的系统包括适于使用由多像素传感器收集的强度信息产生目标的偏振图像的处理器。

公开(公告)号：US09250133B2

公开(公告)日：2016-02-02

申请号：US13108040

申请日：2011-05-16

Applicant: Yoel Arieli ,  Yosef Weitzman

Inventor： Yoel Arieli ,  Yosef Weitzman

IPC: G01J3/45 ,  G01B9/02

CPC classification number: G01J3/447 ,  G01B9/02 ,  G01B11/02 ,  G01J3/0224 ,  G01J3/027 ,  G01J3/12 ,  G01J3/2823 ,  G01J3/32 ,  G01J3/45 ,  G01J3/453 ,  G01N21/211 ,  G01N21/31 ,  G01N21/4795 ,  G02F1/13336

Abstract: There is provided a method for analyzing optical properties of an object, including utilizing a light illumination having a plurality of amplitudes, phases and polarizations of a plurality of wavelengths impinging from the object, obtaining modified illuminations corresponding to the light illumination, applying a modification to the light illumination thereby obtaining a modified light illumination, analyzing the modified light illumination, obtaining a plurality of amplitudes, phases and polarizations maps of the plurality of wavelengths, and employing the plurality of amplitudes, phases and polarizations maps for obtaining output representing the object's optical properties. An apparatus for analyzing optical properties of an object is also provided.

Abstract translation: 提供了一种用于分析物体的光学特性的方法，包括利用具有从物体入射的多个波长的多个振幅，相位和极化的光照，获得对应于光照射的修改照明，对 光照明，从而获得修改的光照明，分析修改的光照明，获得多个波长的多个振幅，相位和极化图，并采用多个幅度，相位和极化映射，以获得表示物体的光学 属性。 还提供了一种用于分析物体的光学特性的装置。

公开(公告)号：US20160022389A1

公开(公告)日：2016-01-28

申请号：US14764087

申请日：2014-02-13

Applicant: 3SHAPE A/S

Inventor： Bo ESBECH ,  Christian Romer ROSBERG ,  Mike VAN DER POEL ,  Rasmus KJAER ,  Michael VINTHER ,  Karl-Josef HOLLENBECK

IPC: A61C9/00 ,  G01J3/51 ,  G01B11/24

CPC classification number: A61C9/0073 ,  A61C9/006 ,  A61C9/0066 ,  G01B11/24 ,  G01B11/2509 ,  G01B11/2513 ,  G01B11/2518 ,  G01J3/0208 ,  G01J3/0224 ,  G01J3/0237 ,  G01J3/0278 ,  G01J3/508 ,  G01J3/51 ,  G01J3/513

Abstract: Disclosed are a scanner system and a method for recording surface geometry and surface color of an object where both surface geometry information and surface color information for a block of said image sensor pixels at least partly from one 2D image recorded by said color image sensor

Abstract translation: 公开了一种用于记录物体的表面几何形状和表面颜色的扫描仪系统和方法，其中至少部分地由所述彩色图像传感器记录的一个2D图像的所述图像传感器像素的块的表面几何信息和表面颜色信息

公开(公告)号：US20150379172A1

公开(公告)日：2015-12-31

申请号：US14768393

申请日：2014-02-05

Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

Inventor： Nicolas VENTROUX ,  Tanguy SASSOLAS

IPC: G06F17/50

CPC classification number: G06F17/509 ,  G01J3/0224 ,  G02B27/286 ,  G06F17/5022

Abstract: A method for accelerating the updating of the linking elements in a simulation of a system generated according to a given hardware description language, the method comprising a phase for evaluating the eligible processes of the system, the evaluation phase comprising write or read accesses to linking elements. For each linking element, two write memory locations are provided. The evaluation phase comprises the updating of a linking element for each write or read access of the linking element. The update comprises the following steps: receive a selection word associated with the linking element; select one of the two write locations associated with the linking element depending on the value of the selection word received for the linking element; and update the current value of the linking element based on the write memory location selected.

Abstract translation: 一种用于在根据给定硬件描述语言生成的系统的仿真中加速链接元素的更新的方法，所述方法包括用于评估系统的合格处理的阶段，评估阶段包括对连接元素的写入或读取访问 。 对于每个链接元素，提供两个写入存储单元。 评估阶段包括更新连接元件的每个写入或读取访问的链接元素。 该更新包括以下步骤：接收与链接元素相关联的选择词; 根据为连接元件接收的选择字的值，选择与链接元素相关联的两个写入位置之一; 并且基于所选择的写入存储器位置来更新链接元素的当前值。

公开(公告)号：US09213227B2

公开(公告)日：2015-12-15

申请号：US13588919

申请日：2012-08-17

Applicant: Eric Peter Goodwin ,  Daniel Gene Smith

Inventor： Eric Peter Goodwin ,  Daniel Gene Smith

IPC: G03B21/53 ,  G02B7/36 ,  G01B11/25 ,  G03F9/00 ,  H05K13/08 ,  G01J3/36 ,  G01J3/02

CPC classification number: G03B21/53 ,  G01B11/2509 ,  G01J3/0224 ,  G01J3/36 ,  G02B7/36 ,  G03F9/7026 ,  G03F9/7049

Abstract: An autofocus (AF) system and method is provided that maps the topography of a substrate such as a semiconductor wafer, in a manner that corrects for Goos Hanchen (GH) effect. In addition, a new and useful detector is provided that is particularly useful in an AF system and method. The detector preferably has both color and polarization filtering integrally associated with the detector, so that polarization and color filtering is provided at the detector, on a pixel by pixel basis.

Abstract translation: 提供了一种自动对焦（AF）系统和方法，其以校正Goos Hanchen（GH）效应的方式映射诸如半导体晶片的衬底的形貌。 另外，提供了一种在AF系统和方法中特别有用的新的和有用的检测器。 检测器优选地具有与检测器一体地相关联的颜色和偏振滤波，使得在检测器处以像素为单位提供偏振和滤色。

公开(公告)号：US09204805B2

公开(公告)日：2015-12-08

申请号：US13678454

申请日：2012-11-15

Applicant: Hypermed Imaging, Inc.

Inventor： Svetlana Panasyuk ,  Jenny Freeman ,  Alexander Panasyuk

IPC: A61B5/00 ,  G01J3/02 ,  G01J3/10 ,  G01J3/28 ,  G01N21/21 ,  G01N21/31 ,  A61B5/02 ,  G01N21/35 ,  G01N21/359

CPC classification number: A61B5/0091 ,  A61B5/0059 ,  A61B5/02007 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/4842 ,  A61B5/742 ,  A61B5/7425 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/0264 ,  G01J3/10 ,  G01J3/2823 ,  G01N21/21 ,  G01N21/31 ,  G01N21/35 ,  G01N21/359 ,  G01N2021/3137 ,  G01N2021/3155 ,  G01N2021/317

Abstract: Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above over time. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer.

Abstract translation: 用于高光谱成像分析的装置和方法，其协助实时和近实时评估生物组织状况，生存力和类型，以及随着时间的推移监测上述情况。 本发明的实施方案在手术，临床程序，组织评估，诊断程序，健康监测和医学评估中特别有用，特别是在癌症的检测和治疗中。

公开(公告)号：US20150331226A1

公开(公告)日：2015-11-19

申请号：US14410067

申请日：2013-06-18

Applicant: GRIMED SAGLIK HIZMETLERI VE BILGISAYAR ÜRÜNLERI SANAYI TICARET LIMITED

Inventor： Osman ESKI

IPC: G02B21/00 ,  G02B21/06 ,  G02B21/26 ,  G02B21/02

CPC classification number: G02B21/0008 ,  A61B5/0064 ,  A61B5/0077 ,  A61B5/441 ,  A61B5/449 ,  A61B5/6898 ,  G01J3/0208 ,  G01J3/0224 ,  G01J3/0235 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/2823 ,  G01J3/32 ,  G01J2003/1213 ,  G01J2003/1221 ,  G01J2003/2826 ,  G02B15/02 ,  G02B21/025 ,  G02B21/06 ,  G02B21/084 ,  G02B21/26 ,  G02B21/36 ,  H04M1/0264 ,  H04M1/21

Abstract: A mobile microscopy device that can be integrated onto mobile imaging devices and mobile phones, and take images in different wavelengths to be used in various fields where microscopic investigation is needed, characterized in that it has a lens module placed into an imaging head and having at least one lens that carries out different magnification rates as needed, a filter module having at least one filter device to filler out reflected light being sent in different wavelengths so as to be sensed by the imaging sensors, and a led module having at least one led to send light beams in different wavelengths.

Abstract translation: 可以集成到移动成像设备和移动电话上的移动显微镜装置，并且将不同波长的图像用于需要进行微观调查的各个领域，其特征在于，其具有放置在成像头中并具有 至少一个透镜，其根据需要执行不同的放大率，滤光器模块具有至少一个滤光器装置，用于填充以不同波长发送的反射光，以便由成像传感器感测，以及具有至少一个LED的LED模块 发送不同波长的光束。

公开(公告)号：US20150308896A1

公开(公告)日：2015-10-29

申请号：US14333406

申请日：2014-07-16

Applicant: Hypermed Imaging, Inc.

Inventor： Mark Anthony Darty

IPC: G01J3/28 ,  G01J3/02 ,  G01J3/447

CPC classification number: A61B5/0075 ,  A61B5/0079 ,  A61B5/1455 ,  A61B5/443 ,  A61B5/447 ,  A61B5/4869 ,  A61B90/30 ,  A61B90/361 ,  A61B2090/309 ,  A61B2090/3618 ,  A61B2560/0425 ,  A61B2562/0233 ,  A61B2562/028 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/12 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/36 ,  G01J3/447 ,  G01J2003/1213 ,  G01J2003/2826 ,  G01N21/255 ,  G01N21/31 ,  G01N21/47 ,  G01N2021/4709

Abstract: A hyperspectral/multispectral imager comprising a housing is provided. At least one light source is attached to the housing. An objective lens, in an optical communication path comprising originating and terminating ends, is further attached to the housing and causes light to (i) be backscattered by the tissue of a subject at the originating end and then (ii) pass through the objective lens to a beam steering element at the terminating end of the communication path inside the housing. The beam steering element has a plurality of operating modes each of which causes the element to be in optical communication with a different optical detector in a plurality of optical detectors offset from the optical communication path. Each respective detector filter in a plurality of detector filters covers a corresponding optical detector in the plurality of optical detectors thereby filtering light received by the corresponding detector from the beam steering element.

Abstract translation: 提供了包括壳体的高光谱/多光谱成像器。 至少一个光源连接到壳体。 在包括起始端和终端的光学通信路径中的物镜进一步附接到壳体，并且使得（i）由发射端的被摄体的组织反向散射，然后（ii）穿过物镜 到达壳体内部的连通路径终端的波束操纵元件。 光束操纵元件具有多个操作模式，每个操作模式使得元件与偏离光通信路径的多个光学检测器中的不同光学检测器进行光通信。 多个检测器滤波器中的每个检测器滤波器覆盖多个光学检测器中的对应的光学检测器，从而从相应的检测器接收的光束从光束操纵元件过滤。