公开(公告)号：US07528952B2

公开(公告)日：2009-05-05

申请号：US11148572

申请日：2005-06-02

Applicant: Malford E. Cullum ,  Istvan Naday ,  Alan L. McArthur

Inventor： Malford E. Cullum ,  Istvan Naday ,  Alan L. McArthur

IPC: G01J3/00 ,  G01J4/00 ,  C12M1/00 ,  C12M3/00

CPC classification number: G01N21/6428 ,  G01N21/6445 ,  G01N33/582 ,  G01N2201/0221

Abstract: A small, portable, hand-sized apparatus for detecting microorganisms or chemicals in liquid samples by fluorescence polarization. The apparatus operates using a low power excitation light source, such as an LED, in order to irradiate a sample with polarized light. Detection of emitted polarized light from the sample is detected in multiple planes simultaneously using low power detectors resulting in an elimination of error caused by drifts in intensity in sequential measurements and in reducing assay time.

Abstract translation: 用于通过荧光偏振检测液体样品中的微生物或化学物质的小型便携式手动大小的装置。 该装置使用诸如LED的低功率激发光源来操作，以便用偏振光照射样品。 使用低功率检测器在多个平面中同时检测来自样品的发射偏振光，从而消除连续测量中强度漂移引起的误差，并减少测定时间。

公开(公告)号：US07485262B2

公开(公告)日：2009-02-03

申请号：US10326332

申请日：2002-12-19

Applicant: Joseph L. DiCesare ,  John T. McCaffrey ,  David Clark ,  Michael I. Crockett

Inventor： Joseph L. DiCesare ,  John T. McCaffrey ,  David Clark ,  Michael I. Crockett

IPC: G01N33/48

CPC classification number: G01N33/52 ,  B01L3/5029 ,  B01L2300/0672 ,  B01L2300/0832 ,  B01L2300/087 ,  B01L2400/0478 ,  B01L2400/0683 ,  C12Q1/66 ,  G01N1/02 ,  G01N21/76 ,  G01N2001/028 ,  G01N2201/0221 ,  Y10T436/16 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface to re-absorb the moisture from the surface.

Abstract translation: 本文公开了用于快速化学发光测定表面以检测微生物污染物的存在的装置和方法。 该装置和方法适合于在现场发现的相对苛刻和可变条件下的未经训练的人员使用，例如在快餐店和其他食物制备区域。 作为所公开的测定装置和方法中的分析信号的来源的化学发光反应优选基于荧光素酶/荧光素系统。 本文公开的采样方法包括以下步骤：将采样拭子预润湿至低于吸收饱和度的水平; 用足够的压力用拭子擦拭待采样的表面以将润湿溶液排出到表面上; 并且在降低施加在取样拭子上的压力之后，进一步擦拭表面以从表面再吸收水分。

公开(公告)号：US20090015686A1

公开(公告)日：2009-01-15

申请号：US12162486

申请日：2007-02-02

Applicant: Bjorn Alsberg

Inventor： Bjorn Alsberg

IPC: H04N5/228 ,  G06K9/00 ,  H04N5/235

CPC classification number: G01J3/2823 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/1256 ,  G01J3/28 ,  G01J3/32 ,  G01N21/255 ,  G01N21/31 ,  G01N2021/1772 ,  G01N2021/1776 ,  G01N2021/3137 ,  G01N2201/0221 ,  G01N2201/129

Abstract: An apparatus for displaying chemical projects a chemical image of an object back onto that object. At region (23) light travels from the object to the apparatus (20) and back from the apparatus as it projects onto the object. Light (24) from the object (22) (which is illuminated by natural light) passes through an objective lens (31) of the apparatus. In its path is rotating mirror (25) and when the mirror is parallel to the path of the rays of light (24), the light is allowed to pass on to hyperspectral camera (26) which is of the AOTF type. The output from the camera is transmitted to processor (27) where the chemical image is generated from the hyperspectral data. The camera generates a series of monochromatic images that are passed to the processor and the chemical image is built up as the camera scans through the appropriate wavelengths. The image data is then transmitted to a projector (28) whose output image is focussed by lens (30) towards the rotating mirror (25). When the mirror is in the position illustrated, the image is reflected off the mirror and back through lens (31) to the imaged object (22).

Abstract translation: 用于显示化学品的装置将物体的化学图像反射回到该物体上。 在区域（23），当物体突出到物体上时，光从物体传播到设备（20）并从设备返回。 来自被摄体（22）的被自然光照射的光（24）通过设备的物镜（31）。 在其路径中是旋转镜（25），并且当镜子平行于光线（24）的路径时，允许光照射到具有AOTF类型的高光谱相机（26）。 来自相机的输出被传送到处理器（27），其中从超光谱数据生成化学图像。 相机生成一系列单色图像，传递到处理器，并且当相机通过适当的波长扫描时，化学图像被建立。 然后将图像数据传输到其输出图像被透镜（30）聚焦到旋转镜（25）的投影仪（28）。 当镜子处于所示的位置时，图像从镜子反射并通过透镜（31）返回到成像对象（22）。

公开(公告)号：US20090014624A1

公开(公告)日：2009-01-15

申请号：US12279074

申请日：2007-02-15

Applicant: Martin Hillebrand Blees ,  Ferry Barrios ,  Wilhelmus Frederik Hoeben ,  Mikhail Sorokin ,  Ludo Haenen ,  Bennie Simpelaar ,  Nebojsa Fisekovic

Inventor： Martin Hillebrand Blees ,  Ferry Barrios ,  Wilhelmus Frederik Hoeben ,  Mikhail Sorokin ,  Ludo Haenen ,  Bennie Simpelaar ,  Nebojsa Fisekovic

IPC: G02B27/64 ,  F21L4/00

CPC classification number: F21L4/027 ,  F21L4/00 ,  F21V29/56 ,  F21V29/83 ,  F21Y2115/10 ,  G01J3/02 ,  G01J3/0272 ,  G01J3/0278 ,  G01J3/0291 ,  G01J3/10 ,  G01N2201/0221 ,  G01N2201/062 ,  G01N2201/0627 ,  G03B15/03

Abstract: The present invention relates to a portable illumination device (100) for illuminating an object (200) through a medium having an absorption coefficient, the illumination device (100) comprising a lighting unit (101) including at least two differently colored light sources (Li-L3) for emitting light having a color distribution, and a control unit (105) for adjusting the color distribution. The control unit (105) is adapted to receive a distance estimate corresponding to the distance between the illumination device (100) and the object (200), and adjust the color distribution depending on the distance estimate, such that light reflected from the object is perceived to have substantially correct color reproduction. An advantage with the invention is that an object (200) illuminated through a medium will be perceived by a user using the portable illumination device (100) as having a substantially correct color reproduction.

Abstract translation: 本发明涉及一种用于通过具有吸收系数的介质照射物体（200）的便携式照明装置（100），所述照明装置（100）包括照明单元（101），所述照明单元包括至少两个不同颜色的光源 -L3），以及用于调整颜色分布的控制单元（105）。 控制单元（105）适于接收与照明装置（100）和物体（200）之间的距离相对应的距离估计，并且根据距离估计调整颜色分布，使得从物体反射的光为 被认为具有基本上正确的色彩再现。 本发明的一个优点是，通过介质照亮的物体（200）将被用户使用便携式照明装置（100）感知为具有基本正确的颜色再现。

公开(公告)号：US20080318266A1

公开(公告)日：2008-12-25

申请号：US12163412

申请日：2008-06-27

Applicant: Malford E. Cullum ,  Lloyd G. Simonson ,  Sylvia Z. Schade ,  Linda A. Lininger ,  Alan L. McArthur

Inventor： Malford E. Cullum ,  Lloyd G. Simonson ,  Sylvia Z. Schade ,  Linda A. Lininger ,  Alan L. McArthur

IPC: C12Q1/02 ,  G01N21/76 ,  G01N33/68 ,  G01N33/92 ,  G01N33/00 ,  G01J4/00

CPC classification number: G01N21/6428 ,  G01N21/6445 ,  G01N33/582 ,  G01N2201/0221 ,  Y10T436/143333

Abstract: The inventive subject matter relates to a method for detecting the presence of a biological substance of interest in a test sample of saliva or oral fluid, comprising combining said test sample with a fluorescence-labeled ligand to said biological substance and detecting a change in the fluorescence polarization of said test sample produced by binding of said fluorescence-labeled ligand to said biological substance. In one aspect of the inventive subject matter, said method comprises additional steps for comparing the fluorescence polarization of said test sample with the fluorescence polarization of a control solution. Also provided is a miniaturized, portable apparatus for measuring the fluorescence polarization of a liquid sample.

Abstract translation: 本发明涉及一种用于检测唾液或口腔液测试样品中感兴趣生物物质的存在的方法，包括将所述测试样品与荧光标记的配体结合到所述生物物质上并检测荧光的变化 通过将所述荧光标记的配体结合到所述生物物质而产生的所述测试样品的极化。 在本发明主题的一个方面，所述方法包括用于将所述测试样品的荧光偏振与对照溶液的荧光偏振进行比较的附加步骤。 还提供了用于测量液体样品的荧光偏振的小型便携式设备。

公开(公告)号：US07460225B2

公开(公告)日：2008-12-02

申请号：US11072330

申请日：2005-03-07

Applicant: Vassili Karanassios

Inventor： Vassili Karanassios

IPC: G01J3/30 ,  G01N1/10

CPC classification number: H01J49/10 ,  G01N21/67 ,  G01N21/69 ,  G01N2021/0346 ,  G01N2201/0221 ,  H01J49/0013 ,  H05H1/30

Abstract: Low-power, low flow-rate, portable, miniaturized plasma devices are provided. A portable, low-power, low flow-rate, miniaturized sample introduction device is also provided. The devices are inexpensive to make, have low operating cost and can be used with a variety of gases and gas mixtures. The devices can be used for elemental analysis from liquid or solid micro-samples by optical emission or mass spectrometry provided that an appropriate sample introduction system is used.

Abstract translation: 提供低功率，低流量，便携式，小型等离子体设备。 还提供了便携式，低功率，低流量，小型化的样品引入装置。 这些装置制造成本低廉，操作成本低，可与各种气体和气体混合使用。 只要使用适当的样品引入系统，该装置可用于通过光学发射或质谱法从液体或固体微量样品进行元素分析。

公开(公告)号：US20080218733A1

公开(公告)日：2008-09-11

申请号：US12041306

申请日：2008-03-03

Applicant: Roman Benes

Inventor： Roman Benes

IPC: G01J3/00

CPC classification number: G01N21/05 ,  G01J3/02 ,  G01J3/0272 ,  G01J3/10 ,  G01J3/42 ,  G01N21/0332 ,  G01N21/314 ,  G01N21/3577 ,  G01N21/359 ,  G01N33/143 ,  G01N33/146 ,  G01N2021/3148 ,  G01N2021/3181 ,  G01N2201/0221 ,  G01N2201/0624 ,  G01N2201/0627 ,  G01N2201/129

Abstract: A method determines an alcohol content of liquids that contain at least water and alcohol as well as sugar or similar substances, in the liquid. The liquid is located in an analysis cell is irradiated by an IR-LED light source, which emits infrared radiation with λ=1000-1500 nm. The IR light absorption is measured at least two different wavelengths, and the measurement values are converted into data on the alcohol content of the liquid. The liquid is irradiated with a first IR radiation with a wavelength λ1, where the absorption coefficient of the alcohol, and the absorption coefficient of the water, are identical in magnitude, and with at least a second IR radiation with a wavelength λ2, where the absorption coefficients and are different. The absorption measurement values determined by an IR detector are applied to a calculating unit for the calculation of the alcohol content.

Abstract translation: 一种方法确定在液体中至少含有水和醇以及糖或类似物质的液体的醇含量。 液体位于分析单元中，由发射λ= 1000-1500nm的红外辐射的IR-LED光源照射。 IR光吸收测量至少两个不同的波长，并且将测量值转换成关于液体的醇含量的数据。 用波长λ1的第一IR辐射照射液体，其中醇的吸收系数和水的吸收系数在大小上是相同的，并且与至少第二个具有波长λ2的IR辐射照射，其中 吸收系数不同。 将由IR检测器确定的吸收测量值应用于用于计算酒精含量的计算单元。

公开(公告)号：US07420663B2

公开(公告)日：2008-09-02

申请号：US11419823

申请日：2006-05-23

Applicant: Sean Xiaolu Wang ,  Xin Jack Zhou

Inventor： Sean Xiaolu Wang ,  Xin Jack Zhou

IPC: G01J3/28

CPC classification number: G01J3/02 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0291 ,  G01N21/64 ,  G01N21/65 ,  G01N21/658 ,  G01N21/718 ,  G01N2201/0221

Abstract: This invention discloses a spectroscopic sensor that is integrated with a mobile communication device, such as a mobile phone. The spectroscopic sensor is capable of measuring the optical spectra of a physical object for purposes of detection, identification, authentication, and real time monitoring. Through the mobile communication device, the obtained spectral information can be transmitted, distributed, collected, and shared by utilizing all the functions of the known or existing wireless communication networks.

Abstract translation: 本发明公开了一种与诸如移动电话的移动通信设备集成的光谱传感器。 光谱传感器能够测量物理对象的光谱，用于检测，识别，认证和实时监控。 通过移动通信设备，通过利用已知或现有的无线通信网络的所有功能，可以发送，分发，收集和共享所获得的频谱信息。

公开(公告)号：US20080204757A1

公开(公告)日：2008-08-28

申请号：US11893750

申请日：2007-08-16

Applicant: Christopher Manning

Inventor： Christopher Manning

IPC: G01B9/02

CPC classification number: G01N21/1702 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/0256 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/4532 ,  G01N2021/1704 ,  G01N2021/3595 ,  G01N2201/0221

Abstract: Novel spectrometer arrangements are described. They may employ a resin-based preconcentration system to sample chemical vapors. A field-widened interferometer modulates radiant energy. The signal generated by the interaction of the radiant energy with the sample is detected and processed by a computer. A variety of enhancements to the basic design are described, providing a family of related spectrometer designs. These spectrometers have applications in spectrometry, spectral imaging and metrology.

Abstract translation: 描述了新型光谱仪布置。 他们可以采用树脂基预浓缩系统来取样化学蒸气。 场扩展的干涉仪调制辐射能。 由辐射能与样品的相互作用产生的信号由计算机检测和处理。 描述了对基本设计的各种增强，提供了一系列相关的光谱仪设计。 这些光谱仪具有光谱，光谱成像和计量学应用。

公开(公告)号：US20080191137A1

公开(公告)日：2008-08-14

申请号：US11822020

申请日：2007-06-29

Applicant: Wade Martin Poteet ,  James Ryles ,  Malcolm Howard Philips

Inventor： Wade Martin Poteet ,  James Ryles ,  Malcolm Howard Philips

IPC: G01J1/42

CPC classification number: G01J3/02 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0278 ,  G01J3/0289 ,  G01J3/42 ,  G01J3/443 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2201/0221

Abstract: The invention relates generally to the field of substance and material detection, inspection, and classification at wavelengths between approximately 200 nm and approximately 1800 nm. In particular, a handheld Enhanced Photoemission Spectroscopy (“EPS”) detection system with a high degree of specificity and accuracy, capable of use at small and substantial standoff distances (e.g., greater than 12 inches) is utilized to identify specific substances (e.g., controlled substances, illegal drugs and explosives, and other substances of which trace detection would be of benefit) and mixtures thereof in order to provide information to officials for identification purposes and assists in determinations related to the legality, hazardous nature and/or disposition decision of such substance(s).

Abstract translation: 本发明一般涉及在约200nm至约1800nm之间的波长处的物质和材料检测，检查和分类领域。 特别地，使用具有高度特异性和精确度的手持式增强型光电发射光谱（“EPS”）检测系统，能够以小而实质的间隔距离（例如，大于12英寸）使用，以识别特定物质（例如， 受控物质，非法药物和爆炸物以及其他有害物质的痕量检测）及其混合物，以向官员提供信息，以便识别目的，并协助确定有关合法性，危险性质和/或处置决定的决定 这些物质。