公开(公告)号：US20180327560A1

公开(公告)日：2018-11-15

申请号：US15954296

申请日：2018-04-16

Applicant: SUMITOMO RUBBER INDUSTRIES, LTD. ,  KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

Inventor： Yasuhisa MINAGAWA ,  Keiji TANAKA ,  Hisao MATSUNO ,  Toyoaki HIRATA

IPC: C08J7/02 ,  C08J3/00

CPC classification number: C08J7/02 ,  B01J20/261 ,  B01J20/3071 ,  B01J20/3078 ,  B01J20/321 ,  B01J20/327 ,  C08J3/005 ,  C08J2325/06 ,  C08J2333/12 ,  C08J2375/04 ,  C08J2433/14

Abstract: Provided is a method of producing a polymer-impregnated base resin which is excellent in providing low adsorption of proteins and blood cells such as platelets. The method of producing a polymer-impregnated base resin includes impregnating a base resin with a polymer solution that includes a solvent able to swell the base resin.

公开(公告)号：US20180273582A1

公开(公告)日：2018-09-27

申请号：US15774979

申请日：2016-11-08

Applicant: UNIVERSITY OF NOTRE DAME

Inventor： Basar BILGICER ,  Nur MUSTAFAOGLU ,  Tanyel KIZILTEPE BILGICER

IPC: C07K1/22 ,  C07K16/28 ,  B01J20/26 ,  B01J20/28 ,  B01J20/288 ,  B01J20/32 ,  B01D15/38 ,  B01D71/10

CPC classification number: C07K1/22 ,  B01D15/3823 ,  B01D15/3828 ,  B01D67/0093 ,  B01D69/144 ,  B01D71/10 ,  B01D71/34 ,  B01D71/68 ,  B01J20/265 ,  B01J20/28033 ,  B01J20/2805 ,  B01J20/288 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3246 ,  C07D209/16 ,  C07K16/065 ,  C07K16/2887 ,  C07K2317/24

Abstract: Disclosed are purification systems and methods for providing purified preparations of antibodies from a fluid, particularly a biological fluid comprising or suspected to contain antibody (e.g., blood, serum, plasma, ascites fluid). Reusable and stable synthetic purification columns comprising membranes of a suitable separation matrix material, such as a nylon membrane or regenerated cellulose membrane, having conjugated thereto a small molecule capture ligand, such as a short peptide or protein capable of acting as a ligand for a particular antibody of interest, such as a peptide having a sequence with binding affinity for a nucleotide binding site (NBS) of a selected antibody of interest, are also provided. Methods of preparing the purification columns are also disclosed. Methods for preparing high yield and high purity therapeutic antibody preparations, such as anti-cancer therapeutics, from a biological fluid, are also presented.

公开(公告)号：US20180237594A1

公开(公告)日：2018-08-23

申请号：US15753096

申请日：2016-04-15

Applicant: LG Chem, Ltd.

Inventor： Yong Hun Lee ,  Hyung Ki Yoon ,  Chang Sun Han ,  Jung Min Sohn

IPC: C08J3/075 ,  C08F2/10 ,  C08F2/44 ,  C08F220/18 ,  C08J3/12 ,  C08K5/053

CPC classification number: C08J3/075 ,  A61L15/60 ,  B01J20/261 ,  B01J20/267 ,  B01J20/28 ,  B01J20/3085 ,  B01J20/321 ,  B01J20/327 ,  C08F2/10 ,  C08F2/44 ,  C08F20/10 ,  C08F220/06 ,  C08F220/18 ,  C08F220/28 ,  C08F2500/01 ,  C08F2800/20 ,  C08F2810/20 ,  C08J3/12 ,  C08J3/245 ,  C08J2333/02 ,  C08J2333/08 ,  C08J2333/10 ,  C08J2335/08 ,  C08K5/053 ,  C08F2220/286 ,  C08F222/385 ,  C08L33/08

Abstract: A preparation method of a superabsorbent polymer, and a superabsorbent polymer prepared thereby are provided. The preparation method of the superabsorbent polymer according to the present disclosure prevents polymer particles from being broken or the surface thereof from being damaged during preparation and handling of the superabsorbent polymer, thereby providing a superabsorbent polymer having excellent absorption properties and permeability.

公开(公告)号：US20180217035A1

公开(公告)日：2018-08-02

申请号：US15936767

申请日：2018-03-27

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Jerald K. Rasmussen ,  Catherine A. Bothof ,  George W. Griesgraber ,  Semra Colak Atan ,  James I. Hembre ,  Robert T. Fitzsimons, JR.

IPC: G01N1/40 ,  B01J20/32 ,  B01D71/44 ,  B01D71/52 ,  B01D71/56 ,  B01J20/26 ,  B01J20/28 ,  G01N33/544 ,  C08J7/18 ,  C07K1/34 ,  C07K1/18 ,  C07F9/38 ,  B01D67/00

CPC classification number: G01N1/405 ,  B01D67/0093 ,  B01D71/44 ,  B01D71/52 ,  B01D71/56 ,  B01D2323/345 ,  B01D2323/38 ,  B01D2325/14 ,  B01D2325/16 ,  B01J20/261 ,  B01J20/28038 ,  B01J20/321 ,  B01J20/3242 ,  B01J20/3251 ,  B01J20/3253 ,  B01J20/327 ,  C07F9/3808 ,  C07K1/18 ,  C07K1/34 ,  C08J7/18 ,  C08J2377/00 ,  G01N1/4077 ,  G01N33/544 ,  G01N2001/4088 ,  G01N2333/924

Abstract: An article that can be used for biomaterial capture comprises (a) a porous substrate; and (b) borne on the porous substrate, a polymer comprising interpolymerized units of at least one monomer consisting of (1) at least one monovalent ethylenically unsaturated group, (2) at least one monovalent ligand functional group selected from acidic groups, basic groups other than guanidino, and salts thereof, and (3) a multivalent spacer group that is directly bonded to the monovalent groups so as to link at least one ethylenically unsaturated group and at least one ligand functional group by a chain of at least six catenated atoms.

公开(公告)号：US20180161722A1

公开(公告)日：2018-06-14

申请号：US15891379

申请日：2018-02-08

Applicant: FUJIFILM CORPORATION

Inventor： Takeo KIDO

IPC: B01D53/26 ,  B01D53/28 ,  B01J20/04 ,  B01J20/10 ,  B01J20/28 ,  B01J20/30 ,  B32B5/14 ,  B32B3/30

CPC classification number: B01D53/263 ,  B01D53/261 ,  B01D53/28 ,  B01J20/046 ,  B01J20/08 ,  B01J20/103 ,  B01J20/18 ,  B01J20/28035 ,  B01J20/28047 ,  B01J20/3007 ,  B01J20/321 ,  B01J20/3236 ,  B01J20/3289 ,  B32B3/30 ,  B32B5/145 ,  B32B15/08 ,  B32B27/08 ,  B32B27/20 ,  B32B27/32 ,  B32B27/36 ,  B32B2250/03 ,  B32B2255/10 ,  B32B2255/20 ,  B32B2255/205 ,  B32B2255/26 ,  B32B2264/102 ,  B32B2264/104 ,  B32B2305/026 ,  B32B2307/7166 ,  B32B2307/724 ,  B32B2307/7242 ,  B32B2307/7246 ,  B32B2307/726 ,  B32B2307/728 ,  B32B2329/04 ,  B32B2553/00

Abstract: Provided is a hygroscopic material including: a support which contains a resin having moisture permeability and has roughness in at least one surface thereof; a hygroscopic layer which is disposed in recesses of the at least one surface of the support; and a damp-proof layer which is disposed on one surface of the support, on which the hygroscopic layer is disposed.

公开(公告)号：US09867927B2

公开(公告)日：2018-01-16

申请号：US14001065

申请日：2012-02-24

Applicant: Naotoshi Tomita ,  Yoshiyuki Ueno ,  Kazuhiro Tanahashi

Inventor： Naotoshi Tomita ,  Yoshiyuki Ueno ,  Kazuhiro Tanahashi

IPC: A61M1/36 ,  B01J20/22 ,  B01J20/28 ,  B01J20/32

CPC classification number: A61M1/3679 ,  B01J20/22 ,  B01J20/28004 ,  B01J20/28016 ,  B01J20/28023 ,  B01J20/28052 ,  B01J20/321 ,  B01J20/3219 ,  B01J20/3251 ,  B01J20/3257 ,  B01J20/3259 ,  B01J20/3293 ,  B01J2220/58

Abstract: A carrier for blood component adsorption enables selective and efficient adsorption removal of granulocytes and monocytes and, at the same time, enables adsorption removal of inflammatory cytokines. The carrier for blood component adsorption includes a water-insoluble carrier having a surface to which a functional group(s) containing a silyl group and an amino group is/are introduced.

公开(公告)号：US09856459B2

公开(公告)日：2018-01-02

申请号：US15163050

申请日：2016-05-24

Applicant: Wisconsin Alumni Research Foundation

Inventor： Mark R. Etzel

IPC: C12N7/00 ,  A61L2/00 ,  B01D61/14 ,  B01D67/00 ,  B01J20/28 ,  B01J20/32 ,  B01J20/26

CPC classification number: C12N7/00 ,  A61L2/0017 ,  B01D61/147 ,  B01D67/0093 ,  B01D2325/12 ,  B01D2325/16 ,  B01J20/261 ,  B01J20/262 ,  B01J20/28033 ,  B01J20/2808 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3248 ,  B01J20/3251 ,  B01J20/3253 ,  B01J20/3255 ,  B01J20/3285 ,  C12N2795/14251

Abstract: A disposable, virus-trapping membrane, and a corresponding method to remove viruses from solution are described. The membrane includes a disposable, micro-porous filter membrane and a ligand immobilized on the membrane. The ligand irreversibly and selectively binds viruses. The ligand also has a pKa sufficiently high to repel antibodies via electrostatic charge repulsion.

公开(公告)号：US20170340998A1

公开(公告)日：2017-11-30

申请号：US15674900

申请日：2017-08-11

Applicant: Rem Brands, Inc.

Inventor： David J. Schneider

IPC: B01D39/14 ,  A61L9/16 ,  A61L9/01 ,  B01D46/10 ,  C02F1/00 ,  B01D46/52 ,  B01D46/12 ,  B01D46/00

CPC classification number: B01D39/14 ,  A61K8/466 ,  A61K2800/10 ,  A61L9/01 ,  A61L9/16 ,  A61L15/46 ,  A61L2209/14 ,  A61Q5/02 ,  A61Q5/06 ,  A61Q17/04 ,  A61Q19/00 ,  B01D46/0038 ,  B01D46/10 ,  B01D46/125 ,  B01D46/525 ,  B01D2239/045 ,  B01D2279/50 ,  B01J20/22 ,  B01J20/28035 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3253 ,  C02F1/001 ,  C02F1/285 ,  C02F2303/02

Abstract: A filter is treated with a reduced amount of a halo active aromatic sulfanomide compound of Formula (I): wherein R1, R2, R3, R4, and R5 are independently selected from hydrogen, COOR′, CON(R″)2, alkoxy, CN, NO2, SO3R″, halogen, substituted or unsubstituted phenyl, sulfonamide, halosulfonamide, and substituted or unsubstituted C1-C12 alkyl; R′ is hydrogen, an alkali metal, an alkaline earth metal, substituted C1-C12 alkyl, or unsubstituted C1-C12 alkyl; and R″ is hydrogen or substituted or unsubstituted C1-C12 alkyl, where the two R″ groups in CON(R″)2 may be independently selected; X is halogen; M is an alkali or alkaline earth metal; and n is the number of water molecules per molecule of the sulfonamide compound. The compound effectively suppresses odors pre-use, in use, and post-use for extended periods of time.

公开(公告)号：US09777075B2

公开(公告)日：2017-10-03

申请号：US15064815

申请日：2016-03-09

Applicant: Lab-on-a-bead AB

Inventor： Sven Oscarsson ,  Kristofer Eriksson ,  Peter Svedlindh

IPC: G01N33/548 ,  C08B37/00 ,  B01J20/285 ,  B01J20/286 ,  B01J20/32 ,  B01J20/28 ,  B01J20/24 ,  G01N33/543 ,  B01D15/38

CPC classification number: C08B37/0039 ,  B01D15/3804 ,  B01D15/3885 ,  B01J20/24 ,  B01J20/28009 ,  B01J20/28016 ,  B01J20/285 ,  B01J20/286 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3217 ,  B01J20/3242 ,  B01J20/3265 ,  G01N33/5434 ,  G01N33/548

Abstract: A novel system for the analysis of molecules and cells, comprising clusters where a non-magnetic particle is supplemented with magnetic particles to form a characteristic pattern, fingerprint or bar code. Methods and devices for formation of such particles are also disclosed.

公开(公告)号：US20170266670A1

公开(公告)日：2017-09-21

申请号：US15479537

申请日：2017-04-05

Applicant: Advantageous Systems, LLC

Inventor： Adam L. STEIN

IPC: B03C1/00 ,  B01J20/28 ,  B01J20/32 ,  B01J20/34 ,  B03C1/01 ,  B03C1/015 ,  B03C1/28 ,  B82Y30/00 ,  C02F1/48 ,  C02F1/68 ,  C08K3/22 ,  C08K5/1545 ,  H01F1/00 ,  C02F1/26 ,  C02F101/12 ,  C02F103/08

CPC classification number: B03C1/00 ,  B01J20/28007 ,  B01J20/28009 ,  B01J20/3204 ,  B01J20/321 ,  B01J20/3212 ,  B01J20/3238 ,  B01J20/324 ,  B01J20/345 ,  B01J20/3475 ,  B03C1/01 ,  B03C1/015 ,  B03C1/288 ,  B03C1/30 ,  B03C2201/18 ,  B03C2201/26 ,  B82Y30/00 ,  C02F1/265 ,  C02F1/288 ,  C02F1/488 ,  C02F1/683 ,  C02F2101/10 ,  C02F2101/106 ,  C02F2101/12 ,  C02F2103/08 ,  C02F2303/04 ,  C02F2305/04 ,  C02F2305/08 ,  C08K3/22 ,  C08K5/1545 ,  C08K2003/2265 ,  C08K2201/01 ,  C08K2201/011 ,  H01F1/0054 ,  Y02W10/37

Abstract: Disclosed are magnetic nanoparticles and methods of using magnetic nanoparticles for selectively removing biologics, small molecules, analytes, ions, or other molecules of interest from liquids.