公开(公告)号：US08269962B2

公开(公告)日：2012-09-18

申请号：US12532723

申请日：2008-03-10

Applicant: Kishan Dholakia ,  Iain Cormack ,  Michael Mazilu

Inventor： Kishan Dholakia ,  Iain Cormack ,  Michael Mazilu

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/10 ,  G01J2003/4424

Abstract: A Raman spectrometer comprising means for illuminating a sample with a shaped laser beam and a detector that is operable to detect light that is reflected from or transmitted through a sample. Preferably, the shaped laser beam has a dark spot at its center.

Abstract translation: 拉曼光谱仪，其包括用成形激光束照射样品的装置和可操作以检测从样品反射或透过样品的光的检测器。 优选地，成形激光束在其中心处具有黑点。

公开(公告)号：US20120228199A1

公开(公告)日：2012-09-13

申请号：US13481028

申请日：2012-05-25

Applicant: Steven H. Modiano ,  Kevin L. Deppermann ,  James Crain ,  Sam R. Eathington ,  Mike Graham

Inventor： Steven H. Modiano ,  Kevin L. Deppermann ,  James Crain ,  Sam R. Eathington ,  Mike Graham

IPC: B07C5/00 ,  G01J3/46 ,  G01B11/24 ,  G01N21/55

CPC classification number: G06K9/00 ,  B07C5/00 ,  B07C5/10 ,  B07C5/34 ,  B07C5/3422 ,  B07C5/3425 ,  G01J3/0218 ,  G01J3/10 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/85 ,  G01N2021/0339 ,  G01N2021/8592 ,  G01N2201/0627 ,  G01N2201/129

Abstract: Systems and methods are provided for evaluating and sorting seeds based on characteristics of the seeds. One system includes an imaging and analysis subsystem that collects image data from the seeds and analyzes the collected image data for characteristics of the seeds. This subsystem can include an imaging theater having minors that reflect image data from the seeds to an imaging device for collection. The system can also include an off-loading and sorting subsystem configured to sort the seeds based on their characteristics. And, one method includes illuminating the seeds and collecting image data from the seeds for determining their characteristics. The image data can be collected from at least three portions of the seeds at each of a plurality of sequentially changing spectral wavelengths. In addition (or alternatively), the image data can be collected from top and bottom portions of the seeds using a single imaging device.

Abstract translation: 提供的系统和方法用于根据种子的特征来评估和分选种子。 一个系统包括成像和分析子系统，其从种子收集图像数据，并分析所收集的图像数据以获得种子的特征。 该子系统可以包括具有将来自种子的图像数据反映到用于收集的成像装置的未成年人的成像影院。 该系统还可以包括卸载和排序子系统，其被配置为基于其特征对种子进行分类。 并且，一种方法包括照亮种子并从种子收集图像数据以确定其特性。 可以从多个顺序变化的光谱波长中的每一个的种子的至少三个部分收集图像数据。 另外（或替代地），可以使用单个成像装置从种子的顶部和底部收集图像数据。

公开(公告)号：US08263949B2

公开(公告)日：2012-09-11

申请号：US13416125

申请日：2012-03-09

Applicant: Claudia B. Jaffe ,  Steven M. Jaffe ,  Arlie R. Conner

Inventor： Claudia B. Jaffe ,  Steven M. Jaffe ,  Arlie R. Conner

IPC: G01J1/58

CPC classification number: G01N21/64 ,  G01J1/58 ,  G01J3/10 ,  G02B6/0003

Abstract: The invention relates to a plurality of light sources to power a variety of applications including microarray readers, microplate scanners, microfluidic analyzers, sensors, sequencers, Q-PCR and a host of other bioanalytical tools that drive today's commercial, academic and clinical biotech labs.

公开(公告)号：US20120220841A1

公开(公告)日：2012-08-30

申请号：US13034454

申请日：2011-02-24

Applicant: Youzhi Li

Inventor： Youzhi Li

IPC: A61B5/1455 ,  G01J3/42

CPC classification number: G01J3/10 ,  A61B5/14552 ,  A61B2560/0209 ,  G01J3/42 ,  G01N21/3151 ,  G01N21/359 ,  G01N2021/3144 ,  G01N2021/3181 ,  H01L2933/0083

Abstract: Systems and methods are provided for spectrophometric measurement of a physiological property of a patient. For example, an embodiment of a patient monitoring system may include a monitor operatively coupled to a spectrophotometric sensor, which may include an emitter configured to transmit light into tissue of the patient and a detector configured to receive the light from the tissue. The emitter may use a photonic crystal light emitting diode to generate the light.

Abstract translation: 提供了用于对患者的生理特性进行光谱测量的系统和方法。 例如，患者监视系统的实施例可以包括可操作地耦合到分光光度传感器的监视器，监视器可以包括被配置为将光透射到患者的组织中的发射器，以及被配置为从组织接收光的检测器。 发射器可以使用光子晶体发光二极管来产生光。

公开(公告)号：US20120218631A1

公开(公告)日：2012-08-30

申请号：US13402007

申请日：2012-02-22

Applicant: Arno Florian Warken ,  Hilmar Gugel

Inventor： Arno Florian Warken ,  Hilmar Gugel

IPC: G02B21/06

CPC classification number: G02B21/0032 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/6458 ,  G02B21/0076 ,  G02B2207/114

Abstract: An illumination device (20) for a microscope (40) has a laser unit (24) that generates at least one broadband laser light pulse (30); light components (71, 72, 73, 74, 75, 76) of different wavelengths of said broadband laser light pulse (30) being offset in time from one another. A compensation unit (36) disposed in the path of the broadband laser light pulse (30) temporally offsets the light components (71, 72, 73, 74, 75, 76) of the broadband laser light pulse (30) in such a way that they exit the compensation unit (36) simultaneously or nearly simultaneously.

Abstract translation: 用于显微镜（40）的照明装置（20）具有产生至少一个宽带激光脉冲（30）的激光单元（24）; 所述宽带激光脉冲（30）的不同波长的光分量（71,72,73,74,75,76）在时间上彼此抵消。 布置在宽带激光脉冲（30）的路径中的补偿单元（36）以这种方式暂时偏移宽带激光脉冲（30）的光分量（71,72,73,74,75,76） 他们同时或几乎同时离开补偿单元（36）。

公开(公告)号：US20120212738A1

公开(公告)日：2012-08-23

申请号：US13364226

申请日：2012-02-01

Applicant: Dar Bahatt ,  Chirag Patel ,  Roy H. Tan ,  Derek Prothro

Inventor： Dar Bahatt ,  Chirag Patel ,  Roy H. Tan ,  Derek Prothro

IPC: G01J3/28

CPC classification number: G01N21/31 ,  G01J3/10 ,  G01J3/12 ,  G01J3/18 ,  G01J3/189 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/4406 ,  G01J2003/1204 ,  G01J2003/1208 ,  G01J2003/1213 ,  G01J2003/1226 ,  G01N21/0332 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G01N2021/6421 ,  G01N2021/6432 ,  G01N2201/06113 ,  G01N2201/0621 ,  G01N2201/0697

Abstract: Systems, including methods, apparatus, and algorithms, for spectrally imaging a two-dimensional array of samples.

Abstract translation: 用于对二维样本阵列进行光谱成像的系统，包括方法，装置和算法。

公开(公告)号：US20120206725A1

公开(公告)日：2012-08-16

申请号：US13154516

申请日：2011-06-07

Applicant: Pajo Vukovic-Cvijin ,  Neil Goldstein

Inventor： Pajo Vukovic-Cvijin ,  Neil Goldstein

IPC: H01S3/10 ,  G01J3/28

CPC classification number: G01J3/433 ,  G01J3/0229 ,  G01J3/10 ,  G01J3/18 ,  G01J2003/423 ,  H01S3/08009 ,  H01S3/0816 ,  H01S5/02248 ,  H01S5/1092 ,  H01S5/141 ,  H01S5/3402 ,  H01S5/4062 ,  H01S5/4087

Abstract: A tunable laser source that includes multiple gain elements and uses a spatial light modulator in an external cavity to produce spectrally tunable output is claimed. Several designs of the external cavity are described, targeting different performance characteristics and different manufacturing costs for the device. Compared to existing devices, the tunable laser source produces high output power, wide tuning range, fast tuning rate, and high spectral resolution.

Abstract translation: 声称包括多个增益元件并且在外部空腔中使用空间光调制器以产生光谱可调谐输出的可调谐激光源。 描述了外部空腔的几种设计，针对设备的不同性能特征和不同的制造成本。 与现有器件相比，可调激光源产生高输出功率，宽调谐范围，快速调谐率和高光谱分辨率。

公开(公告)号：US08234078B2

公开(公告)日：2012-07-31

申请号：US12882131

申请日：2010-09-14

Applicant: Mary-Ann Mycek ,  Malavika Chandra ,  James Scheiman ,  Robert H. Wilson ,  Diane Simeone ,  Barbara McKenna ,  Julianne Purdy ,  Jeremy Taylor ,  Oliver Lee

Inventor： Mary-Ann Mycek ,  Malavika Chandra ,  James Scheiman ,  Robert H. Wilson ,  Diane Simeone ,  Barbara McKenna ,  Julianne Purdy ,  Jeremy Taylor ,  Oliver Lee

IPC: G01N33/48 ,  G06F7/60 ,  G06G7/58

CPC classification number: A61B5/415 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/418 ,  A61B5/7264 ,  A61B5/7267 ,  G01J3/10 ,  G01J3/4406 ,  G01N21/474 ,  G01N21/6408 ,  G01N21/645 ,  G01N21/6486 ,  G01N33/57438 ,  G01N2021/4742 ,  G01N2021/6484 ,  G01N2201/1293

Abstract: Multimodal optical spectroscopy systems and methods produce a spectroscopic event to obtain spectroscopic response data from biological tissue and compare the response data with an empirical equation configured to correlate the measured response data and the most probable attributes of the tissue, thus facilitating classification of the tissue based on those attributes for subsequent biopsy or remedial measures as necessary.

Abstract translation: 多光谱光谱系统和方法产生光谱事件以从生物组织获得光谱响应数据，并将响应数据与配置为将测量的响应数据和组织的最可能属性相关联的经验方程进行比较，从而促进基于组织的分类 关于随后活检的这些属性或必要的补救措施。

公开(公告)号：US20120188552A1

公开(公告)日：2012-07-26

申请号：US13353583

申请日：2012-01-19

Applicant: Nozomu HIROKUBO

Inventor： Nozomu HIROKUBO

IPC: G01J3/45 ,  G02B5/28 ,  G01B9/02

CPC classification number: G02B26/001 ,  G01J3/027 ,  G01J3/10 ,  G01J3/26 ,  G01J3/51

Abstract: A variable wavelength interference filter includes a fixed substrate having a fixed reflecting film, a movable substrate having a movable reflecting film, and an electrostatic actuator including a fixed electrode and a movable electrode. The fixed electrode includes first and second fixed partial electrodes electrically isolated from each other. First and second extraction electrodes extending from the first and second fixed partial electrodes, respectively, are formed on the fixed substrate. The movable electrode is formed in a ring shape covering first and second facing regions facing the first and second fixed partial electrodes, respectively.

Abstract translation: 可变波长干涉滤光器包括具有固定反射膜的固定基板，具有可移动反射膜的可移动基板和包括固定电极和可动电极的静电致动器。 固定电极包括彼此电隔离的第一和第二固定部分电极。 分别从第一和第二固定部分电极延伸的第一和第二提取电极分别形成在固定基板上。 可动电极形成为分别覆盖面向第一和第二固定部分电极的第一和第二面对区域的环形。

公开(公告)号：US20120184832A1

公开(公告)日：2012-07-19

申请号：US13430451

申请日：2012-03-26

Applicant: Mohamed Kheir Diab ,  Esmaiel Kiani-Azarbayjany ,  Charles Robert Ragsdale ,  James M. Lepper, JR.

Inventor： Mohamed Kheir Diab ,  Esmaiel Kiani-Azarbayjany ,  Charles Robert Ragsdale ,  James M. Lepper, JR.

IPC: A61B5/1455

CPC classification number: A61B5/1495 ,  A61B5/0205 ,  A61B5/02427 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  A61B2562/08 ,  G01J3/02 ,  G01J3/0254 ,  G01J3/027 ,  G01J3/0275 ,  G01J3/0291 ,  G01J3/10 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3151 ,  G01N21/39 ,  G01N2021/3144 ,  G01N2201/0627

Abstract: Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like.

Abstract translation: 本公开的实施例还包括能够向身体组织衰减之后除了表示光强度的信号之外，向患者监视器传送识别信息的光学探针。 识别信息可以指示光源的操作波长，指示探针的类型，例如探针是成人探针，儿科探针，新生儿探针，一次性探针，可重复使用的探针等 。 该信息也可以用于安全目的，例如，以确保探针被适当地配置用于血氧计，以指示探针来自授权供应商等。