公开(公告)号：US07463345B2

公开(公告)日：2008-12-09

申请号：US11647195

申请日：2006-12-29

Applicant: Jeffrey K. Cohen ,  John Maier ,  Robert Schweitzer

Inventor： Jeffrey K. Cohen ,  John Maier ,  Robert Schweitzer

IPC: G01J3/26

CPC classification number: G01N21/65 ,  G01J3/0235 ,  G01J3/0264 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/12 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/6458 ,  G01N21/6486 ,  G01N21/658 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/656

Abstract: A system and method of correlating Raman measurements with digital images of a treated sample to classify the disease state of the sample. A spectroscopic data set is obtained for the sample positioned in the field of view of a spectroscopic device. Information about the field of view is stored. The sample is removed from the field of view and treated. The treated sample is repositioned in the field of view using the stored information. A digital image of the treated sample is obtained and the spectroscopic data set is linked with the digital image. A database is provided having a plurality of spectroscopic data sets. Each data set is linked to a corresponding digital image, and associated with the known sample. Each corresponding digital image is associated with the known treated samples. The database is searched to identify and match a data set of a known sample and the sample.

Abstract translation: 将拉曼测量与经处理样品的数字图像相关联以将样品的疾病状态分类的系统和方法。 对于位于分光装置的视野中的样品获得光谱数据集。 存储有关视野的信息。 将样品从视野中移除并进行处理。 使用存储的信息，在视野中重新定位被处理的样品。 获得经处理样品的数字图像，并将光谱数据集与数字图像相连。 提供具有多个光谱数据集的数据库。 每个数据集都链接到相应的数字图像，并与已知样本相关联。 每个相应的数字图像与已知的处理样品相关联。 搜索数据库以识别和匹配已知样本和样本的数据集。

公开(公告)号：US20080204757A1

公开(公告)日：2008-08-28

申请号：US11893750

申请日：2007-08-16

Applicant: Christopher Manning

Inventor： Christopher Manning

IPC: G01B9/02

CPC classification number: G01N21/1702 ,  G01J3/02 ,  G01J3/0229 ,  G01J3/0256 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/4532 ,  G01N2021/1704 ,  G01N2021/3595 ,  G01N2201/0221

Abstract: Novel spectrometer arrangements are described. They may employ a resin-based preconcentration system to sample chemical vapors. A field-widened interferometer modulates radiant energy. The signal generated by the interaction of the radiant energy with the sample is detected and processed by a computer. A variety of enhancements to the basic design are described, providing a family of related spectrometer designs. These spectrometers have applications in spectrometry, spectral imaging and metrology.

Abstract translation: 描述了新型光谱仪布置。 他们可以采用树脂基预浓缩系统来取样化学蒸气。 场扩展的干涉仪调制辐射能。 由辐射能与样品的相互作用产生的信号由计算机检测和处理。 描述了对基本设计的各种增强，提供了一系列相关的光谱仪设计。 这些光谱仪具有光谱，光谱成像和计量学应用。

公开(公告)号：US20080191137A1

公开(公告)日：2008-08-14

申请号：US11822020

申请日：2007-06-29

Applicant: Wade Martin Poteet ,  James Ryles ,  Malcolm Howard Philips

Inventor： Wade Martin Poteet ,  James Ryles ,  Malcolm Howard Philips

IPC: G01J1/42

CPC classification number: G01J3/02 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0278 ,  G01J3/0289 ,  G01J3/42 ,  G01J3/443 ,  G01N21/645 ,  G01N2021/6417 ,  G01N2201/0221

Abstract: The invention relates generally to the field of substance and material detection, inspection, and classification at wavelengths between approximately 200 nm and approximately 1800 nm. In particular, a handheld Enhanced Photoemission Spectroscopy (“EPS”) detection system with a high degree of specificity and accuracy, capable of use at small and substantial standoff distances (e.g., greater than 12 inches) is utilized to identify specific substances (e.g., controlled substances, illegal drugs and explosives, and other substances of which trace detection would be of benefit) and mixtures thereof in order to provide information to officials for identification purposes and assists in determinations related to the legality, hazardous nature and/or disposition decision of such substance(s).

Abstract translation: 本发明一般涉及在约200nm至约1800nm之间的波长处的物质和材料检测，检查和分类领域。 特别地，使用具有高度特异性和精确度的手持式增强型光电发射光谱（“EPS”）检测系统，能够以小而实质的间隔距离（例如，大于12英寸）使用，以识别特定物质（例如， 受控物质，非法药物和爆炸物以及其他有害物质的痕量检测）及其混合物，以向官员提供信息，以便识别目的，并协助确定有关合法性，危险性质和/或处置决定的决定 这些物质。

公开(公告)号：US07389027B2

公开(公告)日：2008-06-17

申请号：US11782481

申请日：2007-07-24

Applicant: Andrew D. Sappey ,  James Howell ,  Henrik Hofvander ,  Bernard Patrick Masterson

Inventor： Andrew D. Sappey ,  James Howell ,  Henrik Hofvander ,  Bernard Patrick Masterson

IPC: G02B6/26

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/024 ,  G01J3/0289 ,  G01J3/0297 ,  G01J3/108 ,  G01J3/1809 ,  G01J5/601 ,  G01J2003/104 ,  G01J2003/423 ,  G01N21/359 ,  G01N21/39 ,  G01N2021/399 ,  G02B6/14

Abstract: A pitch side optical system for use in diode laser spectroscopy consisting of more than one diode laser having select lasing frequencies with each diode laser being coupled to an end of a distinct input optical fiber. The pitch side optical system further consists of a multiplexer optically coupled to the other end of less than all of the input optical fibers with the multiplexer outputting multiplexed laser light to a pitch side optical fiber. The pitch side optical system further consists of a coupler optically coupled to the far end of the pitch side optical fiber and the far end of an unmultiplexed input optical fiber with the coupler combining the multiplexed laser light and the unmultiplexed laser light and outputting the combined light to a transmission optical fiber. Typically, the coupler is located near the combustion process. The pitch side optical system further consists of a pitch optic coupled to the transmission optical fiber. Typically, all optical fibers used in the pitch side optical system are single mode optical fibers.

Abstract translation: 用于二极管激光光谱的俯仰侧光学系统，其由具有选择的激光频率的多于一个的二极管激光器组成，每个二极管激光器耦合到不同的输入光纤的端部。 音调侧光学系统还包括多路复用器，其光耦合到少于所有输入光纤的另一端，多路复用器将多路复用的激光输出到音调侧光纤。 俯仰侧光学系统还包括光耦合到俯仰侧光纤的远端的耦合器和未复用输入光纤的远端，耦合器组合复用的激光和未复用的激光，并输出组合的光 传输光纤。 通常，耦合器位于燃烧过程附近。 俯仰侧光学系统还包括耦合到传输光纤的俯仰光学器件。 通常，在俯仰侧光学系统中使用的所有光纤都是单模光纤。

公开(公告)号：US20080100836A1

公开(公告)日：2008-05-01

申请号：US11925102

申请日：2007-10-26

Applicant: Thomas Hagler

Inventor： Thomas Hagler

IPC: G01J3/02

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0229 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/06 ,  G01J3/1804 ,  G01J3/2846 ,  G01J3/42 ,  G01J2001/4242 ,  G01J2003/1217

Abstract: A method of generating a design pattern for a spatial radiation modulator to encode two or more selected spectral components in one or more spectral ranges for the chemometric analysis of a group of analytes. The method includes obtaining a corresponding spectrum for each of the analytes, defining a set of initial spectral windows, constructing a chemometric matrix to relate concentrations of the analytes to intensities of the spectral components, deriving optimized spectral windows, and translating the center wavelength and the bandwidth of each of the optimized spectral windows into a corresponding optimized annular region on the modulator.

Abstract translation: 一种生成用于空间辐射调制器的设计图案的方法，用于对一组或多个分析物的化学计量分析的一个或多个光谱范围中的两个或更多个选定的光谱分量进行编码。 该方法包括获得每个分析物的相应光谱，定义一组初始光谱窗口，构建化学计量矩阵以将分析物的浓度与光谱分量的强度相关联，导出优化的光谱窗口以及平移中心波长和 每个优化的频谱窗口的带宽转换成调制器上相应的优化的环形区域。

公开(公告)号：US20080073484A1

公开(公告)日：2008-03-27

申请号：US11900644

申请日：2007-09-11

Applicant: David Kane

Inventor： David Kane

IPC: G01J1/20

CPC classification number: G01S17/89 ,  G01J3/021 ,  G01J3/0256 ,  G01J3/0289 ,  G01S17/023 ,  G02B26/0833 ,  G02B26/105

Abstract: In preferred forms of the invention an array of MEMS mirrors or small mirrors inside an optical system operates closed-loop. These mirrors direct external source light, or internally generated light, onto an object—and detect light reflected from it onto a detector that senses the source. Local sensors measure mirror angles relative to the system. Sensor and detector outputs yield source location relative to the system. One preferred mode drives the MEMS mirrors, and field of view seen by the detector, in a raster, collecting a 2-D or 3-D image of the scanned region. Energy reaching the detector can be utilized to analyze object characteristics, or with an optional active distance-detecting module create 2- or 3-D images, based on the object's reflection of light back to the system. In some applications, a response can be generated. The invention can detect sources and locations for various applications.

Abstract translation: 在本发明的优选形式中，光学系统内的MEMS镜或小镜的阵列操作闭环。 这些镜子将外部光源或内部产生的光线直接引导到物体上，并将从其反射的光检测到感测光源的检测器上。 本地传感器测量相对于系统的镜面角度。 传感器和检测器输出产生相对于系统的源位置。 一种优选的方式是在光栅中驱动MEMS反射镜和检测器所看到的视野，收集扫描区域的2-D或3-D图像。 可以利用到达检测器的能量来分析物体特征，或者通过可选的有源距离检测模块，基于物体反射回系统的光线来创建2或3-D图像。 在某些应用中，可以产生响应。 本发明可以检测各种应用的源和位置。

公开(公告)号：US20070252990A1

公开(公告)日：2007-11-01

申请号：US11740138

申请日：2007-04-25

Applicant: Heinrich Grueger

Inventor： Heinrich Grueger

IPC: G01J3/28 ,  G01J3/44 ,  G01J3/30

CPC classification number: G01J3/06 ,  G01J3/02 ,  G01J3/0289 ,  G01J3/2823

Abstract: An apparatus for the detection of spectral information along a geometrical line with a dispersive element, which is suspended from an axis of rotation, for the spectral dispersion of electromagnetic radiation from a range on the geometrical line into spectral constituents, a line detector for the detection of the spectral constituents of the radiation emanating from the range on the geometrical line and a dispersive-element deflector, the deflector being designed to deflect the dispersive element on the axis of rotation, so that depending on an angle of deflection a radiation from another range of the geometrical line is incident on the line detector.

Abstract translation: 一种用于沿着几何线检测光谱信息的装置，其具有从旋转轴悬挂的色散元件，用于从几何线上的范围到电磁成分的电磁辐射的光谱色散，用于检测的线检测器 从几何线上的范围发射的辐射的光谱成分和色散元件偏转器，偏转器被设计成使色散元件偏转在旋转轴上，使得根据偏转角取决于来自另一范围的辐射 几何线入射在线检测器上。

公开(公告)号：US07262853B2

公开(公告)日：2007-08-28

申请号：US10669110

申请日：2003-09-23

Applicant: Steven H. Peterson ,  Mark A. Cargill

Inventor： Steven H. Peterson ,  Mark A. Cargill

IPC: G01J3/50

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/50 ,  G01J3/501 ,  G01J3/524

Abstract: An LED-based color measurement instrument including an illumination system and a sensing system. The illumination system includes modulated LEDs and a temperature control system for regulating the temperature of the LEDs, thereby improving the consistency of their performance. The sensing system includes a photodiode, a transimpedance amplifier, and an integrator in the first stage to cancel the effect of ambient light on the output of the first stage. The sensing system also includes a lens system for imaging a target area of the target sample onto the photo sensor in a manner so that the product of the target area times the solid angle captured by the lens system is generally uniform over a selected range of distances, thereby reducing the positional sensitivity of the instrument with respect to the target sample.

Abstract translation: 一种基于LED的彩色测量仪器，包括照明系统和感测系统。 照明系统包括调制LED和用于调节LED温度的温度控制系统，从而提高其性能的一致性。 感测系统包括第一级中的光电二极管，跨阻放大器和积分器，以消除环境光对第一级输出的影响。 感测系统还包括透镜系统，用于将目标样本的目标区域成像到光传感器上，使得目标区域的乘积乘以由透镜系统捕获的立体角度的乘积在选定的距离范围内大致均匀 ，从而降低了仪器相对于目标样品的位置灵敏度。

公开(公告)号：US07248755B2

公开(公告)日：2007-07-24

申请号：US10543288

申请日：2004-03-31

Applicant: Andrew D Sappey ,  James Howell ,  Henrick Hofvander ,  Bernard Patrick Masterson

Inventor： Andrew D Sappey ,  James Howell ,  Henrick Hofvander ,  Bernard Patrick Masterson

IPC: G02B6/00

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/024 ,  G01J3/0289 ,  G01J3/0297 ,  G01J3/108 ,  G01J3/1809 ,  G01J5/601 ,  G01J2003/104 ,  G01J2003/423 ,  G01N21/359 ,  G01N21/39 ,  G01N2021/399 ,  G02B6/14

Abstract: A sensing apparatus consisting of more than one diode laser having select lasing frequencies, a multiplexer optically coupled to the outputs of the diode lasers with the multiplexer being further optically coupled to a pitch side optical fiber. Multiplexed laser light is transmitted through the pitch side optical fiber to a pitch optic operatively associated with a process chamber which may be a combustion chamber or the boiler of a coal or gas fired power plant. The pitch optic is oriented to project multiplexed laser output through the process chamber. Also operatively oriented with the process chamber is a catch optic in optical communication with the pitch optic to receive the multiplexed laser output projected through the process chamber. The catch optic is optically coupled to an optical fiber which transmits the multiplexed laser output to a demultiplexer. The demultiplexer demultiplexes the laser light and optically couples the select lasing frequencies of light to a detector with the detector being sensitive to one of the select lasing frequencies.

Abstract translation: 由多于一个具有选择的激光频率的二极管激光器组成的感测装置，多路复用器光学耦合到二极管激光器的输出端，多路复用器进一步光耦合到俯仰侧光纤。 多路复用激光通过俯仰侧光纤传输到与可以是燃烧室或煤或燃气发电厂的锅炉的处理室可操作地连接的俯仰光学器件。 俯仰光学器件定向成投影通过处理室的多路复用激光输出。 还与操作室一起操作地定向的是与俯仰光学器件光学通信的接收光学器件，以接收通过处理室投射的多路复用的激光输出。 捕捉光学器件光耦合到将多路复用的激光输出传输到解复用器的光纤。 解复用器解复用激光并将选择的激光频率光耦合到检测器，检测器对选择的激光频率之一敏感。

公开(公告)号：US20070127022A1

公开(公告)日：2007-06-07

申请号：US11647195

申请日：2006-12-29

Applicant: Jeffrey Cohen ,  John Maier ,  Robert Schweitzer

Inventor： Jeffrey Cohen ,  John Maier ,  Robert Schweitzer

IPC: G01J3/28

CPC classification number: G01N21/65 ,  G01J3/0235 ,  G01J3/0264 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/12 ,  G01J3/2823 ,  G01J3/44 ,  G01N21/6458 ,  G01N21/6486 ,  G01N21/658 ,  G01N2021/6417 ,  G01N2021/6423 ,  G01N2021/656

Abstract: A system and method of correlating Raman measurements with digital images of a treated sample and using this correlation to classify the disease state of the sample. A spectroscopic data set is obtained for the sample positioned in the field of view of a spectroscopic device. The positional information about the field of view is stored. With the sample removed from the field of view, the sample is treated with a contrast enhancing agent. Using the stored positional information for the field of view, the treated sample is repositioned in the spectroscopic device's field of view. A digital image of the treated sample positioned in the field of view is obtained. The spectroscopic data set is linked with the digital image by defining a transformation to map the image spatial coordinates of the digital image to the spectral spatial coordinates of the spectroscopic data. A database having a plurality of spectroscopic data sets, for samples having well characterized pathology, is provided. Each spectroscopic data set is linked to a corresponding digital image, and each spectroscopic data set is associated with the known sample. Each corresponding digital image is associated with the known sample treated with a contrast enhancing agent. For the spectroscopic data set of the sample, the database is searched to identify a spectroscopic data set, of a known sample, matching the sample's spectroscopic data set.

Abstract translation: 将拉曼测量与处理的样品的数字图像相关联并使用该相关性来分类样品的疾病状态的系统和方法。 对于位于分光装置的视野中的样品获得光谱数据集。 存储关于视场的位置信息。 从样品中取出样品后，用对比度增强剂处理样品。 使用所存储的视场的位置信息，处理的样品在分光装置的视场中重新定位。 获得定位在视场中的被处理样品的数字图像。 通过定义将数字图像的图像空间坐标映射到光谱数据的光谱空间坐标的变换，光谱数据集与数字图像相关联。 提供了具有多个光谱数据集的数据库，用于具有良好表征的病理学的样本。 每个光谱数据集与相应的数字图像相关联，并且每个光谱数据集与已知样本相关联。 每个相应的数字图像与用对比度增强剂处理的已知样品相关联。 对于样本的光谱数据集，搜索数据库以识别与样本的光谱数据集匹配的已知样本的光谱数据集。