公开(公告)号：US20170319185A1

公开(公告)日：2017-11-09

申请号：US15590094

申请日：2017-05-09

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Seonmyeong CHOI ,  Woochang LEE ,  June Young LEE

IPC: A61B10/00 ,  A61B5/145 ,  A61B5/15

CPC classification number: A61B10/0045 ,  A61B5/0075 ,  A61B5/1405 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1495 ,  A61B2560/0223 ,  G01J3/28 ,  G01J3/42 ,  G01J3/44 ,  G01N21/35 ,  G01N21/359 ,  G01N33/4833 ,  G01N2201/129

Abstract: Disclosed is a method for predicting an in vivo concentration of an analyte, including: estimating an in vivo intrinsic spectrum of the analyte; and predicting the in vivo concentration of the analyte by using a concentration predicting algorithm based on the estimated in vivo intrinsic spectrum and an in vivo spectrum obtained during a section in which the in vivo concentration of the analyte is not substantially changed.

公开(公告)号：US09797876B2

公开(公告)日：2017-10-24

申请号：US15357225

申请日：2016-11-21

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  A61B5/145 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18 ,  G01M3/38

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A measurement system includes semiconductor light sources generating an input beam, optical amplifiers receiving the input beam and delivering an intermediate beam, and fused silica fibers with core diameters less than 400 microns receiving and delivering the intermediate beam to the fibers forming a first optical beam. A nonlinear element receives the first optical beam and broadens the spectrum to at least 10 nm through a nonlinear effect to form the output optical beam which includes a near-infrared wavelength of 700-2500 nm. A measurement apparatus is configured to receive the output optical beam and deliver it to a sample to generate a spectroscopy output beam. A receiver receives the spectroscopy output beam having a bandwidth of at least 10 nm and processes the beam to generate an output signal, wherein the light source and the receiver are remote from the sample, and wherein the sample comprises plastics or food industry goods.

公开(公告)号：US20170285030A1

公开(公告)日：2017-10-05

申请号：US15491305

申请日：2017-04-19

Applicant: UNIVERSITY OF CENTRAL LANCASHIRE

Inventor： Matthew James BAKER ,  Peter ABEL ,  Robert William LEA

IPC: G01N33/574

CPC classification number: G01N33/57407 ,  G01J3/433 ,  G01N21/35 ,  G01N21/552 ,  G01N21/63 ,  G01N33/49 ,  G01N33/574 ,  G01N2021/3196 ,  G01N2021/3595 ,  G01N2030/743 ,  G01N2201/129 ,  G01N2800/52 ,  G01N2800/7028

Abstract: The present invention relates to methods of diagnosing and/or prognosing proliferative disorders, especially brain cancers (e.g. gliomas). In particular, the present invention provides a means to conveniently detect malignant tumours merely by assaying or analysing blood (particularly blood serum). Cytokines and/or angiogenesis factors in blood serum have been found to be surprisingly powerful at indicating the presence of brain cancers in a subject. Moreover, spectroscopic analysis, especially ATR-FTIR analysis, of a blood sample has been demonstrated to be surprisingly effective at producing a signature that can be correlated with the presence, extent, severity, or aggressiveness of malignant tumours in a subject.

公开(公告)号：US09757040B2

公开(公告)日：2017-09-12

申请号：US15357136

申请日：2016-11-21

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  A61B5/00 ,  A61B5/1455 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  A61B5/145 ,  G01N33/15 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18 ,  G01M3/38

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A wearable device for use with a smart phone or tablet includes a measurement device having a plurality of LEDs generating a near-infrared input optical beam that measures physiological parameters. The measurement device includes lenses configured to receive and to deliver the input beam to skin which reflects the beam. The measurement device includes a reflective surface configured to receive and redirect the light from the skin, and a receiver configured to receive the reflected beam. The light source is configured to increase a signal-to-noise ratio of the input beam reflected from the skin by increasing the light intensity from the LEDs and modulation of the LEDs. The measurement device is configured to generate an output signal representing a non-invasive measurement on blood contained within the skin. The wearable device is configured to wirelessly communicate with the smart phone or tablet which receives and processes the output signal.

公开(公告)号：US20170248567A1

公开(公告)日：2017-08-31

申请号：US15594053

申请日：2017-05-12

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: G01N33/15 ,  A61B5/1455 ,  A61B5/145 ,  G01J3/10 ,  G01J3/28 ,  G01N33/02 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/88 ,  G01J3/14 ,  G01N33/44 ,  A61B5/00 ,  G01J3/453

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302 ,  Y02A90/26

Abstract: A wearable device for measuring physiological parameters includes a light source having a plurality of semiconductor light emitting diodes (LEDs) each configured to generate an output optical beam, wherein at least a portion of the one or more optical beam wavelengths is a near-infrared wavelength. The light source is configured to increase signal-to-noise ratio by increasing light intensity for at least one of the LEDs and by increasing a pulse rate of at least one of the LEDs. A lens is configured to receive the output optical beam and to deliver a lens output beam to tissue. A detection system generates an output signal in response to the lens output beam reflected from the tissue, wherein the detection system is configured to be synchronized to the light source, and is located a different distance from a first one of the LEDs than a second one of the LEDs.

公开(公告)号：US09726599B2

公开(公告)日：2017-08-08

申请号：US15361765

申请日：2016-11-28

Applicant: Panasonic Corporation

Inventor： Yumi Wakita ,  Jun Ozawa ,  Naoshi Kondo ,  Yuuichi Ogawa ,  Tetsuhito Suzuki

IPC: G01N21/00 ,  G01N21/31 ,  G01J3/42 ,  G01N33/12 ,  G01N21/84 ,  G08B21/18

CPC classification number: G01N21/314 ,  G01J3/42 ,  G01J2003/425 ,  G01N21/31 ,  G01N21/3151 ,  G01N21/84 ,  G01N33/12 ,  G01N2021/3155 ,  G01N2201/0635 ,  G01N2201/12 ,  G01N2201/129 ,  G08B21/182

Abstract: A freshness estimation method includes obtaining an absorbance spectrum that is obtained by irradiating an eye of a fish with light having all or part of a wavelength band from 315 nm to 450 nm; and estimating freshness of the fish by using a shape of the obtained absorbance spectrum.

公开(公告)号：US20170219484A1

公开(公告)日：2017-08-03

申请号：US15500658

申请日：2014-08-18

Applicant: Foss Analytical A/S

Inventor： Per Waaben HASSEN ,  Henrik Vilstrup JUHL ,  Lars NOERGAARD ,  Andreas BAUM ,  Joern Dalgaard MIKKELSEN

IPC: G01N21/3577 ,  G06F19/00 ,  G01N33/14 ,  C12Q1/37 ,  G01N33/04 ,  G01N21/75

CPC classification number: G01N21/3577 ,  C12Q1/37 ,  G01N21/1717 ,  G01N21/75 ,  G01N33/04 ,  G01N33/143 ,  G01N33/146 ,  G01N2201/127 ,  G01N2201/129 ,  G01N2333/9648 ,  G16C10/00 ,  G16C20/10 ,  G16C20/70

Abstract: A method of determining a constituent related sample property of a multi-constituent sample comprising: subjecting the sample to a perturbation selected to induce a time dependent change in measurement data associated with a constituent related to the sample property to be determined; recording a time-series of measurement data following subjecting the sample to the perturbation; and determining the sample property from the application to the recorded time-series of measurement data of a calibration correlating the sample property with time-series of measurement data, said calibration being empirically derived from chemometric time-series modelling of time-series measurement data recorded for each of a plurality of reference samples following subjecting each reference sample to the perturbation, each reference sample having a different known values of the sample property.

公开(公告)号：US09678015B2

公开(公告)日：2017-06-13

申请号：US14865413

申请日：2015-09-25

Applicant: Frito-Lay North America, Inc. ,  Applied Spectra, Inc.

Inventor： Scott Fagan ,  Paul Allan Martin ,  Scotty G. Richardson ,  Richard E. Russo ,  Chen C. Shao ,  Jong Hyun Yoo ,  Chunyi Liu

IPC: G01J3/30 ,  G01N21/84 ,  G01N21/71 ,  G01N21/85 ,  G01J3/443 ,  G01N33/02

CPC classification number: G01N21/84 ,  G01J3/443 ,  G01N21/718 ,  G01N21/85 ,  G01N33/02 ,  G01N2021/845 ,  G01N2201/129

Abstract: A method and apparatus for analyzing one or more elements of targeted moving snack food surfaces uses laser-induced breakdown spectroscopy to detect the presence, absence, or amount of an element on a heterogeneous surface, including seasoned and ready-to-eat snack foods. A laser is used to quantify the element concentration without destroying the targeted sample. An automated on-line system may be integrated into the method to create a closed-loop feedback control system, adjusting the concentration as desired.

公开(公告)号：US20170154421A1

公开(公告)日：2017-06-01

申请号：US15409355

申请日：2017-01-18

Applicant: Cellular Research, Inc.

Inventor： Glenn Fu ,  Roger Rudoff ,  David Stern ,  George T. Wu ,  Stephen P.A. Fodor ,  Geoffrey Facer

IPC: G06T7/00 ,  G01N21/64

CPC classification number: G06T7/0012 ,  G01N21/274 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N2021/6439 ,  G01N2201/129 ,  G06K9/6267 ,  G06T7/277 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30072 ,  G06T2207/30242

Abstract: Methods, systems and platforms for digital imaging of multiple regions of an array, and detection and counting of the labeled features thereon, are described.

公开(公告)号：US20170138860A1

公开(公告)日：2017-05-18

申请号：US15322874

申请日：2015-07-02

Applicant: NATIONAL UNIVERSITY OF SINGAPORE

Inventor： Zhiwei HUANG

IPC: G01N21/65 ,  A61B5/00 ,  A61B1/018

CPC classification number: G01N21/65 ,  A61B1/018 ,  A61B5/0075 ,  A61B5/0084 ,  A61B2560/0223 ,  G01J3/0218 ,  G01J3/44 ,  G01J2003/123 ,  G01N21/274 ,  G01N2201/0612 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129

Abstract: Characterizing, identifying, or diagnosing the type and/or nature of a sample or a tissue such as an abnormal growth using a Raman spectrum includes analyzing distinct spectral subintervals within the Raman spectrum in two distinct wavelength ranges, such as FP and HW wavelength ranges, to identify a match with one or more reference markers in one or both wavelength ranges; and from the match characterizing, identifying, or diagnosing the type and/or nature of the sample or tissue. FP and HW Raman spectra can be detected or acquired simultaneously using a single diffraction grating.