公开(公告)号：US20230277065A1

公开(公告)日：2023-09-07

申请号：US18118013

申请日：2023-03-06

Applicant: Omni Medsci, Inc.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  G01J3/02 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/145 ,  G01N33/15 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  A61B5/1455 ,  G16Z99/00 ,  A61C19/04 ,  G01N21/3504

CPC classification number: A61B5/0088 ,  A61B5/0075 ,  G01J3/108 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  A61B5/7257 ,  G01J3/0218 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4547 ,  G01N33/15 ,  G01N33/49 ,  G01J3/2823 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/442 ,  G01N21/88 ,  A61B5/6801 ,  A61B5/7405 ,  A61B5/742 ,  G01N33/025 ,  A61B5/1455 ,  G16Z99/00 ,  A61B5/7203 ,  A61C19/04 ,  G01J3/02 ,  G01N21/3504 ,  G01N2201/129 ,  H01S3/302

Abstract: A measurement system comprising one or more semiconductor diodes configured to penetrate tissue comprising skin. The detection system comprising a camera, which may also include a direct or indirect time-of-flight sensor. The detection system synchronized to the pulsing of the semiconductor diodes, and the camera further coupled to a processor. The detection system non-invasively measuring blood within the skin, measuring hemoglobin absorption between 700 to 1300 nm, and the processor deriving physiological parameters and comparing properties between different spatial locations and variation over time. The semiconductor diodes may comprise vertical cavity surface emitting lasers, and the detection system may comprise single photon avalanche photodiodes. The measurement system may be used to observe eye parameters and differential blood flow. The system may be used with photo-bio-modulation therapy, or it may be used in advanced driver monitoring systems for multiple functions including head pose, eye tracking, facial authentication, and smart restraint control systems.

公开(公告)号：US11747201B2

公开(公告)日：2023-09-05

申请号：US17375897

申请日：2021-07-14

Applicant: UNIVERSITY OF THE WEST OF SCOTLAND

Inventor： Ewan Waddell ,  Desmond Gibson

IPC: G01J3/10 ,  G01J3/02 ,  G01J3/12 ,  G01J3/42 ,  G01N21/3504 ,  G01N21/3577

CPC classification number: G01J3/108 ,  G01J3/0208 ,  G01J3/12 ,  G01J3/42 ,  G01J2003/1226 ,  G01N21/3504 ,  G01N21/3577

Abstract: An optical sensor for multispectral analysis of a fluid sample comprises at least one light source, at least one interference filter, and a plurality of light detectors arranged such that light emitted by the at least one light source is incident on the at least one interference filter. There is a spatial variation in the intensity of light incident on the said at least one interference filter.

公开(公告)号：US11678802B2

公开(公告)日：2023-06-20

申请号：US16085210

申请日：2017-03-16

Applicant: OHIO STATE INNOVATION FOUNDATION

Inventor： James Coe ,  Heather Allen ,  Charles Hitchcock ,  Edward W. Martin

IPC: A61B5/00 ,  G01N21/552 ,  G01N21/3563 ,  G01J3/42 ,  A61B90/00 ,  A61B17/00

CPC classification number: A61B5/0075 ,  A61B5/444 ,  G01J3/42 ,  G01N21/3563 ,  G01N21/552 ,  A61B2017/00061 ,  A61B2090/373 ,  A61B2505/05 ,  A61B2576/00 ,  G01J2003/425

Abstract: Systems and methods utilize an infrared probe and discriminating software to rapidly discriminate normal tissue processes from normal tissue during surgery, physical examination of in-situ lesions, and in the assessment of biopsy and resected tissue specimens. Examples demonstrate discrimination of cancerous from noncancerous tissues. The discriminating software, i.e. the metrics, algorithms, calibrant spectra, and decision equations, allows tissue to be identified as abnormal or normal using a minimum of infrared (IR) wavelengths in order to be measured rapidly. The probe records IR metrics approximately 1000 times faster than current commercial instruments, i.e. on a timescale fast enough for clinical use. The probe uses a tunable mid-infrared laser with a small set of selected wavelengths that are optimized for detecting the chemical and molecular signatures of tissue specific lesions to include, but not limited to, cancer, preneoplasia, intracellular accumulations (e.g. steatosis), inflammation, and wound healing.

公开(公告)号：US11674846B2

公开(公告)日：2023-06-13

申请号：US17447951

申请日：2021-09-17

Applicant: VIAVI Solutions Inc.

Inventor： Curtis R. Hruska

IPC: G01J3/02 ,  G01J3/42 ,  G01N21/27 ,  G01J3/10

CPC classification number: G01J3/0297 ,  G01J3/027 ,  G01J3/42 ,  G01N21/274 ,  G01J3/0205 ,  G01J3/10 ,  G01N2201/1273 ,  G01N2201/12707 ,  G01N2201/12715 ,  G01N2201/12723 ,  G01N2201/12738

Abstract: A device may determine a calibration value for a spectrometer using light from a first light source; deactivate the first light source after determining the calibration value; perform measurement with regard to a sample based on the calibration value, wherein the measurement of the sample is performed using light from a second light source; determine that the calibration value is to be updated; and update the calibration value using the light from the first light source.

公开(公告)号：US20230172455A1

公开(公告)日：2023-06-08

申请号：US18103408

申请日：2023-01-30

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  G01J3/02 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/145 ,  G01N33/15 ,  G01N33/49 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/44 ,  G01N21/88 ,  A61B5/1455 ,  G16Z99/00 ,  A61C19/04 ,  G01N21/3504

CPC classification number: A61B5/0088 ,  A61B5/0075 ,  G01J3/108 ,  G01J3/28 ,  G01J3/14 ,  G01J3/453 ,  G01J3/42 ,  A61B5/7257 ,  G01J3/0218 ,  G01N21/35 ,  G16H40/67 ,  G01N21/359 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/4547 ,  G01N33/15 ,  G01N33/49 ,  G01J3/2823 ,  G01N21/3563 ,  G01N21/39 ,  G01N33/02 ,  G01N33/442 ,  G01N21/88 ,  A61B5/6801 ,  A61B5/7405 ,  A61B5/742 ,  G01N33/025 ,  A61B5/1455 ,  G16Z99/00 ,  A61B5/7203 ,  A61C19/04 ,  G01J3/02 ,  G01N21/3504 ,  G01N2201/129 ,  H01S3/302

Abstract: An optical system operating in the near or short-wave infrared wavelength range identifies an object based on water absorption. The system comprises a light source with modulated light emitting diodes operating at wavelengths near 1090 and 1440 nanometers, corresponding to lower and higher water absorption. The system further comprises one or more wavelength selective filters and a housing that is further coupled to an electrical circuit and a processor. The detection system comprises photodetectors that are synchronized to the light source, and the detection system receives at least a portion of light reflected from the object. The system is configured to identify the object by comparing the reflected light at the first and second wavelength to generate an output value, and then comparing the output value to a threshold. The optical system may be further coupled to a wearable device or a remote sensing system with a time-of-flight sensor.

公开(公告)号：US20190195802A1

公开(公告)日：2019-06-27

申请号：US16325632

申请日：2017-08-30

Applicant: OUTSENSE DIAGNOSTICS LTD.

Inventor： Ishay Attar ,  Yaara Kapp-Barnea

IPC: G01N21/64 ,  A61B10/00 ,  G01N33/493

CPC classification number: G01N21/6486 ,  A61B10/0038 ,  A61B10/007 ,  A61B2010/0006 ,  E03D11/13 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/42 ,  G01J5/0806 ,  G01J5/0809 ,  G01J5/10 ,  G01J2003/104 ,  G01N21/31 ,  G01N21/645 ,  G01N33/493 ,  G01N33/57419 ,  G01N2021/6421

Abstract: Apparatus and methods are described for use with feces of a subject that is disposed within a toilet bowl (23), and an output device (32). One or more light sensors (60, 62, 64, 66) receive light from the toilet bowl, while the feces are disposed within the toilet bowl. A computer processor (44) analyzes the received light, and, in response thereto, determines that there is a presence of blood within the feces, and determines a source of the blood from within the subject's gastrointestinal tract. The computer processor (44) generates an output on the output device (32), at least partially in response thereto. Other applications are also described.

公开(公告)号：US20190186991A1

公开(公告)日：2019-06-20

申请号：US15844228

申请日：2017-12-15

Applicant: Horiba Instruments Incorporated

Inventor： Ronald Joseph KOVACH ,  Salvatore Hauptmann ATZENI

IPC: G01J3/02 ,  G01J3/18 ,  G01J3/42

CPC classification number: G01J3/0256 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0235 ,  G01J3/0237 ,  G01J3/0291 ,  G01J3/04 ,  G01J3/18 ,  G01J3/1838 ,  G01J3/40 ,  G01J3/42 ,  G01J2003/045 ,  G01J2003/1842

Abstract: An optical instrument for spectroscopy applications includes a compact arrangement having a three-dimensional folded optical path. A plate configured as an optical reference plane is secured to a housing and is configured to secure optical components above or below the plate. A modular light source module may be secured within the housing without fasteners. A monochromator and spectrometer are secured below the plate. Mirrors disposed above the plate are configured to direct light from the monochromator passing through a first opening in the plate through a sample disposed above the plate, and to direct light from the sample through a second opening in the plate to the spectrometer. A controller is configured for communication with the monochromator and the spectrometer. The controller may control an entrance slit actuator for the spectrometer and positioning of an aperture upstream of the spectrometer to adjust resolution and throughput.

公开(公告)号：US20190183346A1

公开(公告)日：2019-06-20

申请号：US16284514

申请日：2019-02-25

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. ISLAM

IPC: A61B5/00 ,  G16H40/67 ,  G01N33/15 ,  G01J3/10 ,  G01J3/28 ,  G01J3/42 ,  G01J3/453 ,  A61B5/145 ,  A61B5/1455 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/88 ,  G01N33/02 ,  G01J3/02 ,  A61C19/04 ,  G01J3/14 ,  G01N33/49 ,  G01N33/44

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0024 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7203 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  A61C1/0046 ,  A61C19/04 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A smart phone or tablet includes laser diodes, at least some of which may be pulsed and generate near-infrared light and include Bragg reflectors to direct light to tissue/skin. An array of laser diodes generates near-infrared light and has an assembly in front of the array that forms the light into a plurality of spots on the tissue/skin. A receiver includes detectors that receive light reflected from the tissue/skin. An infrared camera receives light reflected from the tissue/skin and generates data based on the received light. The smart phone or tablet is configured to generate a two-dimensional or three-dimensional image using at least part of the data from the infrared camera.

公开(公告)号：US20190113387A1

公开(公告)日：2019-04-18

申请号：US16211516

申请日：2018-12-06

Applicant: Samsung Electronics Co., Ltd.

Inventor： Jaesung LEE ,  Minho PARK ,  Donghyun LEE ,  Daehyeong LIM ,  Keumsun CHOE ,  Jongmin CHOI ,  Changryong HEO

IPC: G01J3/42 ,  G01J3/10

CPC classification number: G01J3/42 ,  G01J3/0224 ,  G01J3/0232 ,  G01J3/0256 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/28 ,  G01J2003/2866

Abstract: According to various embodiments of the present invention, an electronic device can comprise: a light-emitting module for emitting light; a reflection module for reflecting the light emitted from the light-emitting module; a spectrometric module; and a light receiving module for receiving at least one wavelength band among a plurality of wavelength bands dispersed by the spectrometric module.

公开(公告)号：US20190064077A1

公开(公告)日：2019-02-28

申请号：US16173838

申请日：2018-10-29

Applicant: TODOS MEDICAL LTD.

Inventor： Joseph KAPELUSHNIK ,  Shaul MORDECHAI ,  Ilana NATHAN ,  Udi ZELIG ,  Rami ZIGDON

IPC: G01N21/84 ,  G01N21/35 ,  A61B5/00 ,  G01J3/42

CPC classification number: G01N21/84 ,  A61B5/0075 ,  G01J3/42 ,  G01N21/35 ,  G01N2021/3595

Abstract: A method is provided including obtaining an infrared (IR) spectrum of a blood plasma sample by analyzing the blood plasma sample by infrared spectroscopy, and based on the infrared spectrum, generating an output indicative of the presence of a solid tumor or a pre-malignant condition. Other applications are also described.