OPTICAL PULSE GENERATING APPARATUS, TERAHERTZ SPECTROSCOPY APPARATUS, AND TOMOGRAPHY APPARATUS
    21.
    发明申请
    OPTICAL PULSE GENERATING APPARATUS, TERAHERTZ SPECTROSCOPY APPARATUS, AND TOMOGRAPHY APPARATUS 审中-公开
    光学脉冲发生装置,TERAHERTZ光谱设备和计算机装置

    公开(公告)号:US20130146769A1

    公开(公告)日:2013-06-13

    申请号:US13818607

    申请日:2011-07-26

    Inventor: Toshihiko Ouchi

    Abstract: An optical pulse generating apparatus that supplies pump light and probe light includes a light source and a modulation unit configured to modulate light emitted from the light source, thereby dividing the light into the pump light and the probe light. The modulation unit is configured such that a frequency for modulating the light is variable. The modulation unit changes a difference between a moment of the pump light incident on an object and a moment of the probe light incident on the object by changing the frequency.

    Abstract translation: 提供泵浦光和探测光的光脉冲发生装置包括光源和被配置为调制从光源发射的光的调制单元,从而将光分成泵浦光和探测光。 调制单元被配置为使得用于调制光的频率是可变的。 调制单元通过改变频率来改变入射到物体上的泵浦光的时刻与入射到物体上的探测光的时刻之间的差异。

    OPTICAL DETECTION APPARATUS
    22.
    发明申请
    OPTICAL DETECTION APPARATUS 审中-公开
    光学检测装置

    公开(公告)号:US20130070246A1

    公开(公告)日:2013-03-21

    申请号:US13613463

    申请日:2012-09-13

    Abstract: An optical detection apparatus used for detecting a tissue includes a light-emitting unit, a spectroscopic unit and a light-sensing array. The light-emitting unit emits light entering into the tissue. The spectroscopic unit receives the light outputted from the tissue and divides the received light into a plurality of rays with different wavelengths. The light-sensing array senses the rays outputted from the spectroscopic unit so as to generate an array spectrum. By the spectroscopic unit, the detection of the rays of multiple wavelengths can be performed without using plural light-emitting diodes for emitting light of different wavelengths. Besides, the user can perceive the detection result (e.g. the location of the abnormal tissue) intuitively by integrating the light-sensing array and the spectroscopic unit.

    Abstract translation: 用于检测组织的光学检测装置包括发光单元,分光单元和光感测阵列。 发光单元发射进入组织的光。 分光单元接收从组织输出的光,并将接收的光分成具有不同波长的多个光线。 感光阵列感测从分光单元输出的光线,以产生阵列光谱。 通过分光单元,可以不使用多个用于发射不同波长的光的发光二极管来执行多个波长的光线的检测。 此外,通过集成光感测阵列和分光单元,用户可以直观地感知检测结果(例如异常组织的位置)。

    Devices and methods for detecting β-haematin and haemozoin
    24.
    发明授权
    Devices and methods for detecting β-haematin and haemozoin 有权
    用于检测血红蛋白和血红素的装置和方法

    公开(公告)号:US08214006B2

    公开(公告)日:2012-07-03

    申请号:US12513990

    申请日:2007-11-09

    Abstract: In the application, the change in the magnetic state of the haemoglobin caused by the malarial infection is exploited by detecting suitable properties of haemozoin which are dependent on the application of a magnetic field. FIG. 1 shows apparatus, shown generally at (10), for performing magneto-optical detection using photo-acoustic techniques. The apparatus (10) comprises a light source (12), producing a beam of optical radiation (14) which passes through a polarizer (16), a variable LC retarder (0 or 180° retardance) (18), and a (chopper 20), before impinging on a sample (22) held in a sample holder (24). The sample is in direct contact with an acoustic detector (26). The apparatus (10) further comprises an electromagnet (28), and a Gauss meter (30) can be utilized to measure the applied magnetic field strength. Advantages associated with this approach are the—possibility of making in vivo measurements, and the avoidance of problems of optical scattering associated with conventional optical measurements on turbid liquids such as whole blood.

    Abstract translation: 在应用中,通过检测依赖于磁场的应用的血红素的合适性质来开发由疟疾感染引起的血红蛋白的磁状态的变化。 图。 图1示出了总体上用(10)示出的用于使用光声技术进行磁光检测的装置。 该设备(10)包括光源(12),产生通过偏振器(16),可变LC延迟器(0或180°延迟)(18)和(斩波器)的光辐射束(14) 20),然后撞击保持在样品架(24)中的样品(22)。 样品与声学检测器(26)直接接触。 装置(10)还包括电磁体(28),并且高斯计(30)可用于测量所施加的磁场强度。 与该方法相关的优点是进行体内测量的可能性,以及避免与诸如全血的混浊液体的常规光学测量相关联的光学散射问题。

    System for determining the concentration of an analyte
    25.
    发明授权
    System for determining the concentration of an analyte 有权
    用于确定分析物浓度的系统

    公开(公告)号:US08160666B2

    公开(公告)日:2012-04-17

    申请号:US11974477

    申请日:2007-10-12

    Abstract: A system for determining the concentration of an analyte in at least one body fluid in body tissue comprises an infrared light source, a body tissue interface, a detector, and a central processing unit. The body tissue interface is adapted to contact body tissue and to deliver light from the infrared light source to the contacted body tissue. The detector is adapted to receive spectral information corresponding to infrared light transmitted through the portion of body tissue being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid, the algorithm adapted to convert the received spectral information into the concentration of the analyte in at least one body fluid.

    Abstract translation: 用于确定身体组织中的至少一种体液中的分析物的浓度的系统包括红外光源,身体组织界面,检测器和中央处理单元。 身体组织界面适于接触身体组织并将红外光源的光传送到被接触的身体组织。 检测器适于接收对应于通过被分析的身体组织部分透射的红外光的光谱信息,并将接收到的光谱信息转换为指示所接收的光谱信息的电信号。 中央处理单元适于将电信号与建立在与体液中的分析物相关的算法上进行比较,该算法适于将接收到的光谱信息转换成至少一个体液中分析物的浓度。

    Extended Range Optical Imaging System for use in Turbid Media
    26.
    发明申请
    Extended Range Optical Imaging System for use in Turbid Media 有权
    扩展范围光学成像系统用于浊度介质

    公开(公告)号:US20120069341A1

    公开(公告)日:2012-03-22

    申请号:US12792183

    申请日:2010-06-02

    CPC classification number: G01N21/4795 G01N21/51 G01N2201/067 G01N2201/105

    Abstract: An extended range optical imaging system and method for use in turbid media generates a beam of coherent light, modulates the beam of coherent light to encode scan information, directs the modulated beam of coherent light from a first location through the turbid medium toward a target, scans the modulated beam of coherent light over the target in a pattern, according to the scan information, to illuminate the target and to cause light to be reflected, detects the modulated light reflected from the target with a sensor at a second location in the turbid medium to derive an output signal that varies in proportion to the modulated reflected light, demodulates the output signal to derive information comprising the scan information, and constructs an image from the output signal and the scan information so derived.

    Abstract translation: 用于混浊介质的扩展范围光学成像系统和方法产生相干光束,调制相干光束以对扫描信息进行编码,将调制的相干光束从第一位置引导通过混浊介质朝向目标, 根据扫描信息,以模式扫描目标上的调制光束的相干光,以照亮目标并引起光被反射,利用传感器在浑浊的第二位置检测从目标物反射的调制光 介质以导出与调制的反射光成比例地变化的输出信号,解调输出信号以导出包括扫描信息的信息,并且从输出信号构建图像和如此导出的扫描信息。

    Lateral flow assay systems and methods
    27.
    发明授权
    Lateral flow assay systems and methods 有权
    侧流测定系统和方法

    公开(公告)号:US08128871B2

    公开(公告)日:2012-03-06

    申请号:US11112807

    申请日:2005-04-22

    Abstract: In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements.

    Abstract translation: 一方面,诊断测试系统包括壳体,读取器和数据分析器。 壳体包括用于接收测试条的端口。 读取器从暴露于光学检查的检测区域的区域的局部区域获得可分离的光强度测量值,其中每个局部区域的特征在于至少一个小于第一维度的表面尺寸。 数据分析器识别从至少一个测试区域获得的光强度测量结果中的一个,并从所识别的光强测量中计算至少一个参数。 在另一方面,读取器从检测区域的暴露表面区域的多个对应区域中的每一个获得相应的一组光强度测量值,并且数据分析器从至少一个光强度测量集合中计算至少一个参数 。

    Assay test strips and reading same
    30.
    发明授权
    Assay test strips and reading same 有权
    测试条和阅读相同

    公开(公告)号:US08043867B2

    公开(公告)日:2011-10-25

    申请号:US12409871

    申请日:2009-03-24

    Abstract: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.

    Abstract translation: 测定试片包括流路,样品接收区,标签,包括感兴趣区域的检测区和至少一个位置标记。 所述至少一个位置标记相对于所述感兴趣区域对齐,使得所述至少一个位置标记的位置指示所述感兴趣区域的位置。 诊断测试系统包括从测试条的暴露区域获得光强度测量的读取器,以及数据分析器,其执行以下至少一个:(a)基于至少一个(a)识别从测试区域获得的光强度测量中的一个 测量从所述至少一个参考特征获得的,以及(b)基于从所述至少一个参考特征获得的至少一个测量值生成修改所述读取器的至少一个操作参数的控制信号。

Patent Agency Ranking