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    ANALYZER AND WARM-UP DETERMINATION METHOD
    31.
    发明申请
    ANALYZER AND WARM-UP DETERMINATION METHOD 审中-公开

    公开(公告)号：US20190195780A1

    公开(公告)日：2019-06-27

    申请号：US16168892

    申请日：2018-10-24

    Applicant: SHIMADZU CORPORATION

    Inventor： Jumpei ZUSHI ,  Hiroyuki YOSHIMURA

    IPC: G01N21/03 ,  G01J3/10

    CPC classification number: G01N21/0332 ,  G01J3/027 ,  G01J3/0286 ,  G01J3/10 ,  G01J2003/106 ,  G01N2021/0162 ,  G01N2201/126

    Abstract: A spectrophotometer 1 comprises a control unit 45 with a warming-up determination unit 452 that determines the completion of a warming-up based on a variation amount of a detection signal in a predetermined duration when a light detector 7 detects a light from a sample chamber without loading the sample. Specifically, the warming-up determination unit 452 calculates a difference between a signal intensity of the detection signal detected by the light detector 7 at the time when the predetermined time passes and a signal intensity of the detection signal detected by the light detector 7 at a previous time and determines that a warming-up is complete when a value of the difference is less than a first threshold value. The warming-up determination unit 452 automatically determines the completion of warming-up independently from the determination by the user.

    Method and device for determining a visual range in daytime fog
    33.
    发明授权
    Method and device for determining a visual range in daytime fog 有权
    用于确定白天雾中视觉范围的方法和装置

    公开(公告)号：US09506859B2

    公开(公告)日：2016-11-29

    申请号：US14777188

    申请日：2014-02-24

    Applicant: Robert Bosch GmbH

    Inventor： Ulrich Stopper ,  Stephan Lenor ,  Stefan Weber

    IPC: G01N21/47 ,  B60R16/023 ,  G01N21/53 ,  G06K9/00 ,  G01J1/44 ,  G01W1/00 ,  G01N15/00 ,  G01N15/06

    CPC classification number: G01N21/47 ,  B60R16/0237 ,  G01J1/44 ,  G01N21/538 ,  G01N2015/0026 ,  G01N2015/0693 ,  G01N2201/0616 ,  G01N2201/126 ,  G01W1/00 ,  G06K9/00791

    Abstract: A method is provided for determining a visual range in daytime fog, the method (800) including a step of reading in and a step of ascertaining. In the step of reading in, coordinates of at least one characteristic point of a brightness curve of a camera image of the fog are read in. The brightness curve represents brightness values of image points of the camera image along a reference axis of the camera image. In the step of ascertaining, a meteorological visual range in the camera image is ascertained using the coordinates, a meteorological contrast threshold, and a processing specification, in order to estimate the visual range in fog. The processing specification images location-dependent and/or direction-dependent scattered light through the fog in the camera image.

    Abstract translation: 提供了一种用于确定白天雾中的视觉范围的方法，所述方法（800）包括读入步骤和确定步骤。 在读入的步骤中，读取雾的照相机图像的亮度曲线的至少一个特征点的坐标。亮度曲线表示摄像机图像沿摄像机图像的参考轴的图像点的亮度值 。 在确定的步骤中，使用坐标，气象对比阈值和处理规范来确定摄像机图像中的气象视觉范围，以估计雾中的视觉范围。 处理规范通过摄像机图像中的雾图像取决于位置和/或方向依赖的散射光。

    DEFECT INSPECTION METHOD AND DEFECT INSPECTION DEVICE
    35.
    发明申请
    DEFECT INSPECTION METHOD AND DEFECT INSPECTION DEVICE 审中-公开
    缺陷检查方法和缺陷检查装置

    公开(公告)号：US20160161422A1

    公开(公告)日：2016-06-09

    申请号：US15042598

    申请日：2016-02-12

    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

    Inventor： Shunichi MATSUMOTO ,  Atsushi TANIGUCHI ,  Toshifumi HONDA ,  Yukihiro SHIBATA ,  Yuta URANO

    IPC: G01N21/95 ,  G01N21/956

    CPC classification number: G01N21/9501 ,  G01N21/956 ,  G01N2201/126 ,  G01N2201/127 ,  H01L22/12 ,  H01L2924/0002 ,  H01L2924/00

    Abstract: A defect inspection method and device for irradiating a linear region on a surface-patterned sample mounted on a table, with illumination light from an inclined direction to the sample, next detecting in each of a plurality of directions an image of the light scattered from the sample irradiated with the illumination light, then processing signals obtained by the detection of the images of the scattered light, and thereby detecting a defect present on the sample; wherein the step of detecting the scattered light image in the plural directions is performed through oval shaped lenses in which elevation angles of the optical axes thereof are different from each other, within one plane perpendicular to a plane formed by the normal to the surface of the table on which to mount the sample and the longitudinal direction of the linear region irradiated with the irradiation light.

    Abstract translation: 一种缺陷检查方法和装置，用于将安装在台上的表面图案样品上的线性区域照射到具有来自倾斜方向的样品的照明光，并在多个方向上检测从所述多个方向散射的光的图像 用照射光照射的样品，然后处理通过检测散射光的图像获得的信号，从而检测样品上存在的缺陷; 其特征在于，通过椭圆形透镜，其光轴的仰角彼此不同，在垂直于由所述平面形成的法线形成的平面的一个平面内，通过椭圆形透镜来检测多个方向上的散射光图像的步骤 用于安装样品的台面和用照射光照射的线性区域的纵向方向。

    Method of Simultaneous Frequency-Sweeping Lifetime Measurements on Multiple Excitation Wavelengths
    37.
    发明申请
    Method of Simultaneous Frequency-Sweeping Lifetime Measurements on Multiple Excitation Wavelengths 有权
    多激发波长同步扫频寿命测量方法

    公开(公告)号：US20150037877A1

    公开(公告)日：2015-02-05

    申请号：US13956212

    申请日：2013-07-31

    Applicant: The Arizona Board of Regents on behalf of the University of Arizona

    Inventor： Leilei Peng ,  Ming Zhao

    IPC: G01N21/64

    CPC classification number: G01N21/6408 ,  G01N21/6428 ,  G01N2021/6421 ,  G01N2021/6432 ,  G01N2021/6441 ,  G01N2201/10 ,  G01N2201/126

    Abstract: A fast fluorescence lifetime microscopic system images FRET between multiple labels in live cells and deep tissue, using a quantitative analysis method to reconstruct the molecular machinery behind the multiplexed FRET phenomenon. The system measures fluorescence lifetime, intensity and anisotropy as images of excitation-emission matrices (EEM) in real time and high speed within a single image scan, performs high-resolution deep-penetrating 3D FRET imaging in live samples, and fully analyzes all possible photon pathways of multiplexed FRET. The system provides a way for systematic and dynamic imaging of biochemical networks in cells, tissue and live animals, which will help to understand mechanisms of genetic disorders, cancers, and more.

    Abstract translation: 快速荧光寿命显微镜系统在活细胞和深部组织中的多个标记之间的FRET图像，使用定量分析方法重建多重FRET现象背后的分子机制。 该系统在单次图像扫描中以实时和高速的方式测量荧光寿命，强度和各向异性作为激发发射矩阵（EEM）的图像，在活样品中进行高分辨率深穿透3D FRET成像，并全面分析所有可能的 复用FRET的光子通路。 该系统为细胞，组织和活体动物中生物化学网络的系统和动态成像提供了一种途径，有助于了解遗传疾病，癌症等机制。

    SYSTEM AND METHOD FOR DENSE-STOCHASTIC-SAMPLING IMAGING
    38.
    发明申请
    SYSTEM AND METHOD FOR DENSE-STOCHASTIC-SAMPLING IMAGING 有权
    用于渗透 - 采样成像的系统和方法

    公开(公告)号：US20140353524A1

    公开(公告)日：2014-12-04

    申请号：US14461779

    申请日：2014-08-18

    Applicant: GE HEALTCARE BIO-SCIENCES CORP.

    Inventor： GAUDENZ DANUSER ,  PAUL C. GOODWIN

    IPC: G01N21/64

    CPC classification number: G01N21/6428 ,  G01N21/636 ,  G01N21/6458 ,  G01N2021/6415 ,  G01N2021/6419 ,  G01N2201/126 ,  G02B21/365 ,  G02B21/367 ,  G06T3/4053

    Abstract: Embodiments of the present invention are directed to imaging technologies, and, in particular, to an imaging system that detects relatively weak signals, over time, and that uses the detected signals to determine the positions of signal emitters. Particular embodiments of the present invention are directed to methods and systems for imaging fluorophore-labeled samples in order to produce images of the sample at resolutions significantly greater than the diffraction-limited resolution associated with optical microscopy. Embodiments of the present invention employ overlapping-emitter-image disambiguation to allow data to be collected from densely arranged emitters, which significantly decreases the data-collection time for producing intermediate images as well as the number of intermediate images needed to computationally construct high-resolution final images. Additional embodiments of the present invention employ hierarchical image-processing techniques to further resolve and interpret disambiguated images.

    Abstract translation: 本发明的实施例涉及成像技术，特别涉及一种随时间检测相对较弱信号的成像系统，并且使用所检测的信号来确定信号发射器的位置。 本发明的具体实施方案涉及用于成像荧光团标记的样品的方法和系统，以便以明显大于与光学显微镜相关联的衍射限制分辨率的分辨率产生样品的图像。 本发明的实施例采用重叠 - 发射 - 图像消歧以允许从密集布置的发射器收集数据，这显着减少用于产生中间图像的数据收集时间以及计算构建高分辨率所需的中间图像的数量 最终图像。 本发明的另外的实施例采用分层图像处理技术来进一步解析和解释消歧图像。

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