公开(公告)号：US09719950B2

公开(公告)日：2017-08-01

申请号：US14630704

申请日：2015-02-25

Applicant: FEI Company

Inventor： Michael James Owen ,  Ashley Donaldson ,  Garth Howell ,  Phillip John Christopher Parker

IPC: G01N23/225 ,  H01J37/252 ,  H01J37/244 ,  G01J3/44

CPC classification number: G01N23/2252 ,  G01J3/44 ,  H01J37/244 ,  H01J37/252 ,  H01J2237/2807

Abstract: A method and apparatus are provided for identifying a material with a sample-specific reference spectral list or library. A sequential approach to SEM-EDS automated mineralogy classification is carried out by performing two or more material classification analyses. A pre-classification step restricts the processing of spectra deconvolution algorithms to a subset of spectra that pass a dominant mineral criteria resulting in a significantly reduced subset of reference spectra that occur within the measured sample in pure enough form at a given minimum quantity. The following complex classification stages involving deconvolution of multiple constituents within measured spectra is based on this sample relevant subset.

公开(公告)号：US20170188901A1

公开(公告)日：2017-07-06

申请号：US15241914

申请日：2016-08-19

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Andrei FARAON ,  Amir ARBABI ,  Yu HORIE

IPC: A61B5/1455 ,  A61B5/145 ,  G01N21/65

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546 ,  A61B2560/0431 ,  A61B2562/0238 ,  A61B2562/0285 ,  G01J3/12 ,  G01J3/18 ,  G01J3/44 ,  G01J2003/1213 ,  G01N21/65 ,  G01N2201/068 ,  G02B27/1006 ,  G02B27/1086

Abstract: A solution containing a target molecule and a reference molecule is illuminated to obtain Raman signals. An optical metasurface is used as a diffractive optical element to split the Raman signal from the target molecule and the Raman signal from the reference molecule. The target and reference Raman signals can be detected at different locations with different photodetectors, and the target molecule concentration in the solution is determined by comparing the target and reference Raman signals.

公开(公告)号：US20170184502A1

公开(公告)日：2017-06-29

申请号：US14981136

申请日：2015-12-28

Applicant: SCHLUMBERGER TECHNOLOGY CORPORATION

Inventor： Albert Ballard Andrews ,  Andrew Speck

IPC: G01N21/65 ,  G01N33/28

CPC classification number: G01N21/65 ,  G01J3/44 ,  G01N33/2835

Abstract: Apparatus and method for Raman-spectrography-based measurement of the composition of gas mixture in a high-temperature borehole. The method includes any of determining molar densities of individual alkanes of the mixture, introducing refractive index corrections, utilization of reference species internally to the measurement apparatus, correction for the effect of self-absorption and cross-absorption, as well as minimizing fluorescence when a liquid fraction is present in the borehole. The apparatus is configured to detect vibrational bands of CH, OH, CC, HS, NN and CO functional groups as well as collective modes in the fingerprint spectral region.

公开(公告)号：US09689743B2

公开(公告)日：2017-06-27

申请号：US13559211

申请日：2012-07-26

Applicant: Huiwen Liu ,  Peter Gunderson

Inventor： Huiwen Liu ,  Peter Gunderson

IPC: G01J3/44 ,  G01J3/00 ,  G01J3/02 ,  G01N21/65

CPC classification number: G01J3/0248 ,  G01J3/0237 ,  G01J3/0278 ,  G01J3/44 ,  G01N21/65

Abstract: The disclosure is related systems and method for improved accuracy and precision in Raman spectroscopy. In one embodiment, a device may comprise a Raman spectroscopic apparatus configured to determine a property of a sample by directing photons at the sample and measuring a resulting Raman scattering, a positioning apparatus capable of manipulating a position of the sample, and the device being configured to selectively adjust a focus of the Raman spectroscopic apparatus to adjust an intensity of the Raman scattering. Another embodiment may be a method comprising performing a depth focus Raman spectra screening on a sample to determine a depth focus with a maximum-intensity Raman spectra, wherein the depth focus spectra screening comprises performing Raman spectra scans on the sample at a plurality of depth foci, and modifying a process based on a result of the Raman spectra scan at the depth focus with the maximum-intensity Raman spectra.

公开(公告)号：US09683991B2

公开(公告)日：2017-06-20

申请号：US14124496

申请日：2012-06-06

Applicant: Qihua Xiong ,  Xinlong Xu ,  Jun Zhang

Inventor： Qihua Xiong ,  Xinlong Xu ,  Jun Zhang

IPC: G01N21/75 ,  G01N33/53 ,  G01J3/44 ,  G01N21/552 ,  G01N21/65 ,  G03F7/20 ,  G02B1/00

CPC classification number: G01N33/5308 ,  G01J3/44 ,  G01N21/554 ,  G01N21/658 ,  G02B1/002 ,  G02F2202/30 ,  G02F2203/10 ,  G03F7/2037

Abstract: A method of generating a metamater-operable in the visible-infrared range is provided. The method comprises a) depositing a layer of a conductive material on a substrate; b) forming a layer of electron beam resist on the layer of conductive material; c) patterning the layer of electron beam resist using electron beam lithography to form a patterned substrate; d) depositing a layer of a noble metal on the patterned substrate; and e) removing the resist. A metamaterial operable in the visible-infrared range comprising split-ring resonators having a least line width of about 20 nm to about 40 nm on a substrate is provided. A transparent photonic device or a sensor for chemical or biological sensing comprising the metamaterial is also provided.

公开(公告)号：US20170146711A1

公开(公告)日：2017-05-25

申请号：US15168395

申请日：2016-05-31

Applicant: AGENCY FOR DEFENSE DEVELOPMENT

Inventor： Yeon-Chul HA ,  Jae-Hwan LEE ,  Young-Su JEONG ,  Sun-Kyung CHOI ,  Young-Jin KOH

IPC: G02B5/28 ,  C23C14/10 ,  C23C14/46 ,  C23C14/08 ,  G01J3/02 ,  G01J3/44

CPC classification number: G02B5/283 ,  C23C14/081 ,  C23C14/10 ,  C23C14/46 ,  G01J3/0205 ,  G01J3/0227 ,  G01J3/44 ,  G01J3/4412 ,  G02B5/285

Abstract: A Raman edge filter and a method of manufacturing the same, wherein in order to obtain a Raman spectrum for compound analysis in a Raman spectrometer using a deep-ultraviolet ray (UV) laser, the Raman edge filter functions to eliminate a deep-UV laser wavelength, which is a light source, and to transmit Raman scattered light.

公开(公告)号：US20170146458A1

公开(公告)日：2017-05-25

申请号：US15316568

申请日：2015-06-03

Applicant: Ludwig-Maximilians-Universität München

Inventor： Robert Alexander Huber ,  Sebastian Karpf ,  Matthias Eibl

IPC: G01N21/64 ,  G01N21/65

CPC classification number: G01N21/6456 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/44 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/65 ,  G01N2021/6484 ,  G01N2201/06146 ,  G01N2201/0635 ,  G01N2201/105 ,  G01N2201/11 ,  G01N2201/12 ,  H01S3/06712 ,  H01S3/06754 ,  H01S3/094007 ,  H01S3/10015 ,  H01S3/1618 ,  H01S3/2316 ,  H01S3/302 ,  H01S2301/02

Abstract: Described is a system for inducing and detecting multi-photon processes, in particular multi-photon fluorescence or higher harmonic generation in a sample. The system comprises a dynamically-controllable light source, said dynamically-controllable light source comprising a first sub-light source, said first sub-light source being electrically controllable such as to generate controllable time-dependent intensity patterns of light having a first wavelength, and at least one optical amplifier, thereby allowing for active time-control of creation of multi-photon-excitation. The system further comprises a beam delivery unit for delivering light generated by said dynamically-controllable light source to a sample site, and a detector unit or detector assembly for detecting signals indicative of said multi-photon process, in particular multi-photon fluorescence signals or higher harmonics signals.

公开(公告)号：US09658166B2

公开(公告)日：2017-05-23

申请号：US15375720

申请日：2016-12-12

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Katsumi Shibayama ,  Masashi Ito ,  Takafumi Yokino ,  Masaki Hirose ,  Anna Yoshida ,  Kazuto Ofuji ,  Yoshihiro Maruyama

IPC: G01J3/44 ,  G01N21/65 ,  G01J3/02

CPC classification number: G01N21/658 ,  B82Y40/00 ,  G01J3/02 ,  G01J3/12 ,  G01J3/44 ,  G01N2201/02 ,  G01N2201/0227 ,  G01N2201/06113

Abstract: A SERS unit comprises a substrate; an optical function part formed on the substrate, for generating surface-enhanced Raman scattering; and a package containing the optical function part in an inert space and configured to irreversibly expose the space.

公开(公告)号：US20170131145A1

公开(公告)日：2017-05-11

申请号：US15156291

申请日：2016-05-16

Applicant: DIRAmed, LLC

Inventor： Richard J. Higgins ,  Brian Lipp ,  Don Warren Caudy

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/27

CPC classification number: G01J3/0297 ,  G01J3/0232 ,  G01J3/28 ,  G01J3/44 ,  G01N21/274

Abstract: Described are a shutter assembly, a spectrometer, and a method for calibrating a spectrometer. For example, the method may include positioning a shutter including a mirror into a first position in an illumination path of an excitation light beam such that a measurement window is blocked. The mirror may be operable to direct at least one of: (1) the illumination path to a spectral calibration material, (2) a first collection path extending from the spectral calibration material, and (3) a second collection path of a spectral calibration light beam. The method may include directing a returned light from the receiving optics unit to an imaging device; processing the returned light at the imaging device into one or more image signals; analyzing and comparing the image signals with approved image signals; and providing an indication of whether the comparative results of the analysis are within acceptable tolerances.

公开(公告)号：US09638638B2

公开(公告)日：2017-05-02

申请号：US14890109

申请日：2014-05-09

Applicant: Ludwig-Maximilians-Universität München

Inventor： Robert Alexander Huber ,  Thomas Klein ,  Wolfgang Wieser ,  Sebastian Karpf ,  Matthias Eibl

IPC: G01J3/44 ,  G01N21/65 ,  H01S3/067 ,  H01S3/10 ,  H01S3/23 ,  H01S3/30 ,  H01S3/0941 ,  H01S3/16 ,  H01S3/00 ,  H01S3/094

CPC classification number: G01N21/65 ,  G01J3/44 ,  G01J3/4412 ,  G01N2021/655 ,  G01N2201/06113 ,  G01N2201/0683 ,  G01N2201/0697 ,  H01S3/0064 ,  H01S3/0078 ,  H01S3/06758 ,  H01S3/094069 ,  H01S3/09415 ,  H01S3/10015 ,  H01S3/1618 ,  H01S3/2391 ,  H01S3/302

Abstract: Disclosed herein is a system (10) for measuring light induced transmission or reflection changes, in particular due to stimulated Raman emission. The system comprises a first light source (12) for generating a first light signal having a first wavelength, a second light source (14) for generating a second light signal having a second wavelength, an optical assembly (16) for superposing said first and second light signals at a sample location (18), and a detection means (24) for detecting a transmitted or reflected light signal, in particular a stimulated Raman signal caused by a Raman-active medium when located at said sample location. Here in at least one of the first and second light sources (12, 14) is one or both of actively controllable to emit a time controlled light pattern or operated substantially in CW mode and provided with an extra cavity modulation means (64) for generating a time controlled light pattern. The detection means (24) is capable of recording said transmitted or reflected light signal, in particular stimulated Raman signal, as a function of time.