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    METHODS OF FABRICATION OF NANO-SENSOR AND NANO-SENSOR ARRAY
    51.
    发明申请
    METHODS OF FABRICATION OF NANO-SENSOR AND NANO-SENSOR ARRAY 审中-公开

    公开(公告)号：US20200240942A1

    公开(公告)日：2020-07-30

    申请号：US16756743

    申请日：2018-10-16

    Applicant: Indian Institute of Science

    Inventor： Chandra Shekhar Prajapati ,  Navakanta Bhat

    IPC: G01N27/12

    Abstract: Methods of fabrication and nano-sensor and nano-sensor array thereof are provided. A sensing electrode assembly can be patterned on a sacrificial layer of a substrate. The sensing electrode assembly can comprise a pair of contact pads and an electrode element coupled to and disposed between the pair of contact pads. The sensing electrode assembly can be formed on the patterned sensing electrode assembly. The sacrificial layer below a portion of the electrode element can be removed to obtain a suspended electrode element. The suspended electrode element can be oxidized at a first predetermined temperature to obtain a pair of electromigrated regions and a notch portion between the pair of the electromigrated regions. The notch portion can be used to detect a gaseous component in an ambient gas at a second predetermined temperature.

    A MULTIDIMENSIONAL MICROFLUID FOCUSING DEVICE
    55.
    发明申请
    A MULTIDIMENSIONAL MICROFLUID FOCUSING DEVICE 审中-公开

    公开(公告)号：US20190257738A1

    公开(公告)日：2019-08-22

    申请号：US16333653

    申请日：2017-09-15

    Applicant: INDIAN INSTITUTE OF SCIENCE ,  DEPARTMENT OF BIOTECHNOLOGY

    Inventor： Eluru GANGADHAR ,  Sai Siva GORTHI

    IPC: G01N15/14 ,  B01L3/00

    Abstract: A multi-dimensional micro fluid focussing device. The device includes an apparatus for multi-dimensional micro fluid focussing. The device also includes an analyser for analysing the focused fluid. The apparatus includes a microchannel having an inlet defining a first region, a middle region and an outlet defining a second region. A first junction is formed at the intersection of the first region and the middle region. A second junction is formed at the intersection of the middle region and the second region. A first sheath positioned proximal to the first junction and a second sheath positioned at the second junction. The junctions formed, along with the positioning of the sheaths enable the multi-dimensional focusing of the fluid. The analyser includes a holder for removably retaining the apparatus. A microscope is positioned across the holder. A recording unit is coupled to the microscope.

    HARDWARE ACCELERATOR FOR ALIGNMENT OF SHORT READS IN SEQUENCING PLATFORMS
    58.
    发明申请
    HARDWARE ACCELERATOR FOR ALIGNMENT OF SHORT READS IN SEQUENCING PLATFORMS 审中-公开

    公开(公告)号：US20180239864A1

    公开(公告)日：2018-08-23

    申请号：US15554592

    申请日：2016-02-17

    Applicant: INDIAN INSTITUTE OF SCIENCE

    Inventor： Santhi NATARAJAN ,  Debnath PAL ,  S. K. NANDY

    IPC: G06F19/22 ,  G06F19/28

    CPC classification number: G16B30/00 ,  G16B50/00

    Abstract: The present disclosure relates to an aligner in a hardware accelerator that can align short reads with a reference genome as genomic data is streamed through the hardware accelerator and thus can speed up the process of alignment. In an aspect, the disclosed short read aligner can incorporate a number of hardware kernels modelled as processor array implementation of the cost function model of the dynamic programming algorithm having a number of processing elements, wherein each kernel can incorporate a traceback control block as a separate hardware that enables traceback in parallel to the processor array and alignment matrix filling process by use of trace back direction vectors and using additional trackback path prediction features. The disclosed aligner can be parameterized and can perform alignment for cost function models of different variations of chosen dynamic programming algorithm. The aligner incorporates adequate sequence partitioning, scheduling, alignment and stitching schemes to accommodate short reads of variable lengths for alignment.

    Method and apparatus for joint adaptation of two-/multi-dimensional equalizer and partial response target
    59.
    发明授权
    Method and apparatus for joint adaptation of two-/multi-dimensional equalizer and partial response target 有权

    公开(公告)号：US10026441B2

    公开(公告)日：2018-07-17

    申请号：US15648985

    申请日：2017-07-13

    Applicant: Indian Institute of Science

    Inventor： Shayan Srinivasa Garani ,  Chaitanya Kumar Matcha ,  Arnab Dey

    IPC: G11B5/035 ,  G11B5/09 ,  G11B20/10

    Abstract: The present disclosure relates to a method and apparatus for processing of multi-dimensional readback signal from magnetic recording or optical, physical data recording so as to reduce/control Inter Symbol Interference (ISI) and noise within acceptable limits. The method is based on Partial Response Maximum Likelihood (PRML) detection and takes care of time varying channel conditions. In an embodiment, the filter coefficients of both the equalizer and the partial response (PR) target are jointly adapted to account for the channel condition for both separable and non-separable targets thus reducing signal detection complexity. In an aspect, the disclosure provides an apparatus that incorporates an adaptation engine along with the equalizer and the PR target that updates filter coefficients of both the equalizer and the PR target following the formulated mathematical equations.

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