公开(公告)号：US20140268104A1

公开(公告)日：2014-09-18

申请号：US13913303

申请日：2013-06-07

Applicant: Chemlmage Corporation

Inventor： Patrick J. Treado ,  Matthew Nelson ,  Charles W. Gardner

IPC: G01J3/44 ,  G01J3/51

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0221 ,  G01J3/0224 ,  G01J3/0248 ,  G01J3/32 ,  G01N21/21 ,  G01N21/314 ,  G01N21/33 ,  G01N21/35 ,  G01N21/3581 ,  G01N21/359 ,  G01N21/65 ,  G02B21/0092 ,  G02B21/16 ,  G02B21/361

Abstract: A first location comprising an unknown material may be scanned using SWIR hyperspectral imaging in a dual polarization configuration. Surveying may also be applied to thereby determine whether or not a human is present. This surveying may be achieved my assessing LWIR data, data acquired from motion sensors, and combinations thereof. If no human is present, a second location may be interrogated using Raman spectroscopic techniques to thereby obtain a Raman data set representative of the region of interest. This Raman data set may be assessed to associate an unknown material with a known material. This assessment may be achieved by comparing the Raman data set to one or more reference data sets in a reference database, where each reference data set is associated with a known material.

Abstract translation: 包含未知材料的第一位置可以使用双极化配置中的SWIR高光谱成像进行扫描。 还可以进行测量，从而确定人是否存在。 本次测量可能会实现我对LWIR数据的评估，运动传感器获取的数据及其组合。 如果不存在人，则可以使用拉曼光谱技术询问第二位置，从而获得表示感兴趣区域的拉曼数据集。 可以评估该拉曼数据集以将未知材料与已知材料相关联。 可以通过将拉曼数据集与参考数据库中的一个或多个参考数据集进行比较来实现该评估，其中每个参考数据集与已知材料相关联。

公开(公告)号：US20140185052A1

公开(公告)日：2014-07-03

申请号：US13727782

申请日：2012-12-27

Applicant: Qiushui Chen

Inventor： Qiushui Chen

IPC: G01B9/02

CPC classification number: G01J3/0224 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/4537

Abstract: The present invention is related to a Fourier-transform spectrometer arrangement comprising a first polarizer, a birefringent plate, a pair of birefringent wedges, a second polarizer, a photo detector, and a control unit. According to the invention, the cross sections of the two birefringent wedges of the birefringent wedge pair are similar triangles, the first wedge is fixed, the second wedge is capable of linearly movement along the side, the optic axes of the pair of birefringent wedges are parallel to each other and orthogonal to the optic axis of the birefringent plate, the polarization of the first polarizer is in 45 degrees with the optical axis of the birefringent plate, the polarization of the first polarizer is also in 45 degrees with the optical axis of the pair of birefringent wedges, the polarization of the second polarizer is parallel, or orthogonal, to the polarization of the first polarizer.

Abstract translation: 本发明涉及包括第一偏振器，双折射板，一对双折射楔形物，第二偏振器，光电检测器和控制单元的傅立叶变换光谱仪装置。 根据本发明，双折射楔形对的两个双折射楔的横截面是相似的三角形，第一楔形件是固定的，第二楔形件能够沿着一侧线性移动，该对双折射楔的光轴是 彼此平行并且与双折射板的光轴正交，第一偏振片的偏振度与双折射板的光轴成45度，第一偏振片的偏振度也在45度的光轴 所述一对双折射楔形物，所述第二偏振片的偏振度与所述第一偏振器的偏振平行或正交。

公开(公告)号：US08743358B2

公开(公告)日：2014-06-03

申请号：US13842098

申请日：2013-03-15

Applicant: ChemImage Corporation

Inventor： Patrick Treado ,  Matthew Nelson ,  Charles Gardner

IPC: G01J3/28

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0221 ,  G01J3/0224 ,  G01J3/32 ,  G01J3/44 ,  G01N21/17 ,  G01N21/21 ,  G01N21/314 ,  G01N21/33 ,  G01N21/35 ,  G01N21/3581 ,  G01N21/359 ,  G02B21/0092 ,  G02B21/16 ,  G02B21/361

Abstract: A first location comprising an unknown material may be scanned using SWIR hyperspectral imaging in a dual polarization configuration. Surveying may also be applied to thereby determine whether or not a human is present. This surveying may be achieved my assessing LWIR data, data acquired from motion sensors, and combinations thereof. If no human is present, a second location may be interrogated using Raman spectroscopic techniques to thereby obtain a Raman data set representative of the region of interest. This Raman data set may be assessed to associate an unknown material with a known material. This assessment may be achieved by comparing the Raman data set to one or more reference data sets in a reference database, where each reference data set is associated with a known material.

Abstract translation: 包含未知材料的第一位置可以使用双极化配置中的SWIR高光谱成像进行扫描。 还可以进行测量，从而确定人是否存在。 本次测量可能会实现我对LWIR数据的评估，运动传感器获取的数据及其组合。 如果不存在人，则可以使用拉曼光谱技术询问第二位置，从而获得表示感兴趣区域的拉曼数据集。 可以评估该拉曼数据集以将未知材料与已知材料相关联。 可以通过将拉曼数据集与参考数据库中的一个或多个参考数据集进行比较来实现该评估，其中每个参考数据集与已知材料相关联。

公开(公告)号：US20140132955A1

公开(公告)日：2014-05-15

申请号：US14124269

申请日：2012-06-06

Applicant: Shogo Kawano ,  Taisuke Ota ,  Minoru Kobayashi

Inventor： Shogo Kawano ,  Taisuke Ota ,  Minoru Kobayashi

IPC: G01N21/65

CPC classification number: G01N21/65 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/44 ,  G01J2003/4424

Abstract: An object of the present invention is to provide a Raman microscope and a Raman spectrometry measuring method, both of which can make a measurement with high wavenumber resolution. The Raman microscope according to one embodiment of the present invention includes a pump light source 12 for emitting pump light as continuous light; a relaxation light source 11 for emitting relaxation light to induce stimulated emission in a sampled a dichroic mirror 14 for irradiating the relaxation light and the pump light to the sample 17; a spectrograph 32 for spectrally separating Raman scattered light generated in the sample 17; and a detector 33 for detecting the Raman scattered light spectrally separated in the spectrograph 32.

Abstract translation: 本发明的目的是提供一种可以进行高波数分辨率测量的拉曼显微镜和拉曼光谱测量方法。 根据本发明的一个实施例的拉曼显微镜包括用于将泵浦光作为连续光发射的泵浦光源12; 松弛光源11，其用于发射放松光，以在用于将弛豫光和泵浦光照射到样品17的采样分色镜14中感应受激发射; 用于光谱分离样品17中产生的拉曼散射光的光谱仪32; 以及用于检测在光谱仪32中光谱分离的拉曼散射光的检测器33。

公开(公告)号：US08664583B2

公开(公告)日：2014-03-04

申请号：US13175563

申请日：2011-07-01

Applicant: Jeffrey H. Hunt ,  John H. Belk

Inventor： Jeffrey H. Hunt ,  John H. Belk

IPC: G02F1/01

CPC classification number: G01N21/55 ,  B82Y30/00 ,  G01J1/0407 ,  G01J1/42 ,  G01J3/0208 ,  G01J3/0224 ,  G01J3/32 ,  G01J3/427 ,  G01J5/023 ,  G01J5/046 ,  G01J5/12 ,  G01J9/00

Abstract: An apparatus, system, and method are disclosed for nonlinear optical surface sensing with a single thermo-electric detector. In particular, the system includes at least two signal sources that are co-aligned to propagate photons to the same location on a surface. The system also includes at least one focusing element that focuses a sequence of photons that is reflected from the location on the surface. In addition, the system includes at least one frequency selective electromagnetic detector that detects the sequence of photons that are focused from the focusing element(s). When the frequency selective electromagnetic detector senses a photon, the frequency selective electromagnetic detector emits an electrical pulse that has a voltage that is proportional to the energy level of the photon. Additionally, the system includes a processor that processes the electrical pulses, and de-multiplexes the sequence of emitted electrical pulses based on the electrical pulse voltage of the electrical pulses.

Abstract translation: 公开了一种使用单个热电探测器进行非线性光学表面感测的装置，系统和方法。 特别地，该系统包括至少两个共同对准以将光子传播到表面上相同位置的信号源。 该系统还包括至少一个聚焦元件，其聚焦从表面上的位置反射的光子序列。 此外，该系统包括至少一个频率选择性电磁检测器，其检测聚焦元件聚焦的光子的序列。 当频率选择性电磁检测器感测到光子时，频率选择性电磁检测器发射具有与光子的能级成比例的电压的电脉冲。 此外，该系统包括处理电脉冲的处理器，并且基于电脉冲的电脉冲电压去除多路复用所发射的电脉冲序列。

公开(公告)号：US20140016116A1

公开(公告)日：2014-01-16

申请号：US13987046

申请日：2013-06-28

Applicant: Chemlmage Corporation

Inventor： John Maier ,  Jeffrey Cohen ,  Ryan Priore

IPC: G01N21/84

CPC classification number: G01N21/84 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/0248 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/1256 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/44 ,  G01J3/4406 ,  G01J5/0846 ,  G01J2005/0077 ,  G01N21/35 ,  G01N21/3581 ,  G01N21/359 ,  G01N21/65 ,  G01N21/658 ,  G01N2201/129 ,  G02B21/0092 ,  G02B21/14 ,  G02B21/16

Abstract: The present disclosure provides for a system and method for assessing chronic exposure of a biological sample, such as a bodily fluid, to an analyte of interest. A biological sample may be illuminated to thereby generate a one or more pluralities of interacted photons. These interacted photons may be detected to thereby generate one or more spectroscopic data sets representative of a biological sample. Spectroscopic data sets generated may be compared to at least one reference data set. Each reference data set may be associated with a known exposure to a known analyte. The present disclosure contemplates that the system and method disclosed herein may be used to analyze exposure of biological samples to at least one analyte over time. Data sets may be obtained at various time intervals to assess changes in a molecular composition as a result of chronic exposure to an analyte.

Abstract translation: 本公开提供了用于评估生物样品（例如体液）到感兴趣分析物的慢性暴露的系统和方法。 可以照射生物样品，从而产生一个或多个相互作用的光子。 可以检测这些相互作用的光子，从而生成代表生物样品的一个或多个光谱数据集。 可以将生成的光谱数据集与至少一个参考数据集进行比较。 每个参考数据集可以与已知分析物的已知暴露相关联。 本公开内容考虑到本文公开的系统和方法可用于分析生物样品随时间的至少一种分析物的暴露。 可以以不同的时间间隔获得数据集，以评估作为慢性暴露于分析物的结果的分子组成的变化。

公开(公告)号：US20130335740A1

公开(公告)日：2013-12-19

申请号：US14001810

申请日：2012-02-28

Applicant: Ichiro Ishimaru

Inventor： Ichiro Ishimaru

IPC: G01N21/23

CPC classification number: G01N21/23 ,  G01J3/0224 ,  G01J3/453

Abstract: A linearly polarized light reaches a sample S through a polarizer and receives a retardation from the sample S. Then, the light reaches a movable mirror unit and a fixed mirror unit of a phase shifter through a first polarizing plate and a second polarizing plate. Then, the reflected measurement lights pass through an analyzer, and are caused by an imaging lens to form an interference image on the light-receiving surface of a detector. At this time, an optical path length difference between a beam reflected on the movable mirror unit and a beam reflected on the fixed mirror unit is continuously changed the movable mirror unit. Hence, the imaging intensity of the interference image detected by the detector continuously changes producing a synthetic waveform similar to an interferogram. The synthetic waveform is Fourier-transformed, to obtain an amplitude per wavelength and a birefringent phase difference per wavelength.

Abstract translation: 直线偏振光通过偏光片到达样品S，并从样品S接收延迟。然后，光通过第一偏振片和第二偏振片到达移相器的可移动镜单元和固定镜单元。 然后，反射的测量光通过分析器，并且由成像透镜引起，以在检测器的光接收表面上形成干涉图像。 此时，可移动镜单元反射的光束与固定镜单元上反射的光束之间的光程长度差连续地变化。 因此，由检测器检测到的干涉图像的成像强度连续变化，产生类似于干涉图的合成波形。 合成波形被傅里叶变换，以获得每波长的振幅和每波长的双折射相位差。

公开(公告)号：US20130335735A1

公开(公告)日：2013-12-19

申请号：US13916813

申请日：2013-06-13

Applicant: The Royal Institution for the Advancement of Learning / McGill University

Inventor： Patanjali Kambhampati ,  Jonathan Saari ,  Pooja Tyagi

IPC: G01J3/10 ,  G01J3/12

CPC classification number: G01J3/10 ,  G01J3/0224 ,  G01J3/08 ,  G01J3/1256 ,  G01J3/433 ,  G01J3/453 ,  G01J9/02

Abstract: Two dimensional (2D) optical spectroscopy, wherein the spectrum has an excitation and an emission axis, reveals information formerly hidden in one-dimensional (1D) optical spectroscopy. However, current two dimensional optical spectroscopy systems are complex laboratory arrangements and accordingly limited in deployment. According to embodiments of the invention a monolithic platform providing significantly reduced complexity and increased robustness is provided allowing for “black-box” modules allowing commercial deployment of 2D optical spectroscopy instruments. Additionally, the invention supports high pulse repetition rates as well as one quantum and two quantum measurements under electronic control.

Abstract translation: 二维（2D）光谱，其中光谱具有激发和发射轴，揭示了先前隐藏在一维（1D）光谱中的信息。 然而，目前的二维光谱系统是复杂的实验室布置，因此在部署中受到限制。 根据本发明的实施例，提供了提供显着降低的复杂性和增强的鲁棒性的单片平台，允许允许商业部署2D光谱仪器的“黑箱”模块。 此外，本发明支持高脉冲重复率以及电子控制下的一个量子和两个量子测量。

公开(公告)号：US20130321806A1

公开(公告)日：2013-12-05

申请号：US13992101

申请日：2011-11-30

Applicant: Robert T. Kester ,  Tomasz S. Tkaczyk

Inventor： Robert T. Kester ,  Tomasz S. Tkaczyk

IPC: G01J3/447

CPC classification number: G01J3/447 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/2823 ,  G01J4/04

Abstract: A method for imaging a sample, the method includes, during a single acquisition event, receiving a first polarization-encoded EM field for a first point and a second polarization-encoded EM field for a second point. The method further includes re-directing the first polarization-encoded EM field along a first pre-determined direction to a first location on a dispersing re-imager and the second polarization-encoded EM field along a second pre-determined direction to a second location on the dispersing re-imager. The method further includes spectrally dispersing the first polarization-encoded EM field to obtain a first spectrum, re-imaging the first spectrum onto a first location on a detector, spectrally dispersing the second polarization-encoded EM field to obtain a second spectrum, re-imaging the second spectrum onto a second location on the detector, and detecting the first re-imaged spectrum and the second re-imaged spectrum.

Abstract translation: 一种用于对样本进行成像的方法，所述方法包括在单个采集事件期间，为第一点接收第一偏振编码的EM场，并为第二点接收第二极化编码的EM场。 该方法还包括将沿着第一预定方向的第一偏振编码的EM场重新定向到分散再成像器上的第一位置，并且将第二偏振编码的EM场沿第二预定方向重新定向到第二位置 在分散重建器上。 该方法还包括光谱分散第一偏振编码的EM场以获得第一光谱，将第一光谱重新成像到检测器上的第一位置上，频谱地分散第二偏振编码的EM场以获得第二光谱， 将第二光谱成像到检测器上的第二位置，以及检测第一重新成像光谱和第二重新成像光谱。

公开(公告)号：US08599381B2

公开(公告)日：2013-12-03

申请号：US13226809

申请日：2011-09-07

Applicant: Eric R. Statz ,  Alan E. DeCew, Jr. ,  Jonathan B. Ashcom

Inventor： Eric R. Statz ,  Alan E. DeCew, Jr. ,  Jonathan B. Ashcom

IPC: G01N21/00 ,  G01N21/39

CPC classification number: G01N21/39 ,  G01J3/0224 ,  G01J3/26 ,  G01J3/42 ,  G01N21/274 ,  G01N21/314 ,  G01N21/3504 ,  G01N2021/1793 ,  G01N2021/3166 ,  G01N2021/3188 ,  G01N2021/3513

Abstract: A gas detector includes a receiver configured to receive light from a light source through gas, the light source having a bandwidth on the order of an absorption linewidth of the gas, the receiver including at least a first etalon having a transmission bandwidth on the order of the absorption linewidth of the gas, the transmission bandwidth of the first etalon being substantially smaller than the bandwidth of the light source. The gas detector further includes a first detector for detecting light transmitted through the first etalon, a second detector for detecting light reflected from the first etalon, and a processor that determines the quantity of gas based on the detected transmitted and reflected light. The gas detector can further include a second etalon with a transmission bandwidth approximately equal and adjacent to the transmission bandwidth of the first etalon. Alternatively, the gas detector can include a beam separator that separates the light from the light source into a first beam and a second beam, with a small deflection angle between the first beam and the second beam, thereby modifying the effective thickness of a single optical element for each beam and forming the first and second etalon in the optical element.

Abstract translation: 气体检测器包括：接收器，被配置为通过气体接收来自光源的光，所述光源具有大约为气体吸收线宽度的带宽，所述接收器至少包括第一标准具，传输带宽为 气体的吸收线宽度，第一标准具的传输带宽显着小于光源的带宽。 气体检测器还包括用于检测通过第一标准具传输的光的第一检测器，用于检测从第一标准具反射的光的第二检测器，以及基于检测到的透射和反射光来确定气体量的处理器。 气体检测器还可以包括第二标准具，其传输带宽近似相等并且与第一标准具的传输带宽相邻。 或者，气体检测器可以包括光束分离器，其将来自光源的光分离成第一光束和第二光束，第一光束和第二光束之间具有小的偏转角，由此修改单个光学器件的有效厚度 元件，并在光学元件中形成第一和第二标准具。