公开(公告)号：US20190351411A1

公开(公告)日：2019-11-21

申请号：US16531253

申请日：2019-08-05

Applicant: Abbott Laboratories

Inventor： Andrew Fischer

IPC: B01L3/00

Abstract: Example methods, apparatus, systems for diluting samples are disclosed. An example method includes depositing a first fluid droplet on a first electrode of a plurality of electrodes. The first electrode has a first area. The first fluid droplet has a first volume associated with the first area. The example method includes depositing a second fluid droplet on a second electrode of the plurality of electrodes. The second electrode has a second area. The second fluid droplet has a second volume associated with the second area. The second volume is different than the first volume. The example method includes forming a combined droplet by selectively activating at least one of the first electrode or the second electrode to cause one of the first fluid droplet or the second fluid droplet to merge with the other of the first fluid droplet or the second fluid droplet.

公开(公告)号：US10481073B2

公开(公告)日：2019-11-19

申请号：US15801055

申请日：2017-11-01

Applicant: Abbott Laboratories

Inventor： Jiong Wu ,  Michael R. Buhl ,  Giacomo Vacca

IPC: G01N15/14 ,  G01N21/64 ,  G01N33/49 ,  G01N15/10 ,  G01N15/00

Abstract: Provided herein are systems and methods for analyzing blood samples, and more specifically for performing a basophil analysis. In one embodiment, the systems and methods include: (a) staining a blood sample with an exclusive cell membrane permeable fluorescent dye; and then (b) using measurements of light scatter and fluorescence emission to distinguish basophils from other WBC sub-populations. In one embodiment, the systems and methods include performing a basophil cluster analysis of the blood sample, based on the combination of light scatter and fluorescence measurements.

公开(公告)号：US20190331705A1

公开(公告)日：2019-10-31

申请号：US16505529

申请日：2019-07-08

Applicant: Abbott Laboratories

Inventor： Robert Luoma

IPC: G01N35/04

Abstract: A diagnostic analyzer includes a first sample process path, a second sample processing path, and a reaction vessel exchanger device. The first sample process path includes an incubation track operable to move reaction vessels along the first sample process path. The second sample process path includes a processing track, disposed below the first sample process path, which is operable to move reaction vessels along the second sample process path. The reaction vessel exchanger device is configured to transfer the reaction vessels from the first sample processing path to the second sample processing path.

公开(公告)号：US20190315844A1

公开(公告)日：2019-10-17

申请号：US16387282

申请日：2019-04-17

Applicant: ABBOTT LABORATORIES

Inventor： Bailin Tu ,  Robert N. Ziemann ,  Bryan C. Tieman ,  Philip M. Hemken ,  Carol S. Ramsay ,  Carolyn J. Strobel ,  David J. Hawksworth ,  Larry G. Birkenmeyer ,  Cheng Zhao ,  Susan E. Brophy ,  Barry L. Dowell ,  Anthony S. Muerhoff

IPC: C07K16/18 ,  G01N33/574 ,  G01N33/68

Abstract: Disclosed herein are antibodies and methods of using said antibodies to detect Golgi protein 73 (GP73) and fucosylated GP73 in a sample.

公开(公告)号：US10444242B2

公开(公告)日：2019-10-15

申请号：US15189646

申请日：2016-06-22

Applicant: ABBOTT LABORATORIES ,  Icahn School of Medicine at Mount Sinai

Inventor： Robert Ziemann ,  April Ahlberg ,  David Hawksworth ,  Bryan Tieman ,  A. Scott Muerhoff ,  Christopher Marohnic ,  Kathy Otis ,  Andrea Branch ,  Francis Eng

IPC: G01N33/576 ,  C07K16/10

Abstract: The present disclosure provides detection methods employing HCV core lipid binding domain and DNA binding domain monoclonal antibodies or antibody fragments. In certain embodiments, the lipid binding domain monoclonal antibody or antibody fragment recognizes an epitope in amino acids 141 to 161 of HCV core protein and the DNA binding domain antibody or antibody fragment recognizes an epitope in amino acids 95-123 (e.g., in amino acids 99-117) of HCV core protein.

公开(公告)号：US20190301999A1

公开(公告)日：2019-10-03

申请号：US16421201

申请日：2019-05-23

Applicant: Abbott Laboratories

Inventor： Svitlana Y. Berezhna ,  Rene Nieves Alicea ,  Kam Lin Wong ,  Damian John Verdnik ,  Leigh Whiting ,  Mahmoud Janbakhsh

IPC: G01N15/14 ,  G06T7/00 ,  G06T7/11 ,  G06K9/46 ,  G01N15/02

Abstract: The present disclosure provides methods for automated slide assessments made in conjunction with digital image-based microscopy. Automated methods of acquiring patient information and specimen information from prepared slides, and digitally linking such information into patient-tagged specimen data, are provided. Also provided are methods that include automatically identifying an optimal area for morphological assessment of a blood smear on a hematological slide, including methods for triggering the analysis of such an area, e.g., using an automated digital image-based hematology system. The present disclosure also provides devices, systems and computer readable media for use in performing processes of the herein described methods.

公开(公告)号：US10421588B2

公开(公告)日：2019-09-24

申请号：US15562126

申请日：2016-03-28

Applicant: ABBOTT LABORATORIES

Inventor： Jason Middleton ,  Spencer Beaufore ,  Jeremy McBroom

IPC: B65D51/16 ,  B65D77/20 ,  B65D77/22 ,  B65D51/20

Abstract: A sealed container for packaging of granular or powdered product including a rigid container body defining an interior space and an upper portion, the upper portion having a sealing lip that defines an opening to the interior space, and a flexible, polymer sealing membrane removably attached to the sealing lip to cover the opening, the sealing membrane including a plurality of laser generated micro-perforations formed through the sealing membrane, the size of each of the plurality of laser generated micro-perforations being less than 3.937 mils.

公开(公告)号：US10413288B2

公开(公告)日：2019-09-17

申请号：US15192481

申请日：2016-06-24

Applicant: Abbott Laboratories

Inventor： Joshua Stafford

IPC: A61B17/04 ,  A61B17/00

Abstract: A device for suturing an opening in a tissue, having an elongated shaft, at least two arms movable to a deployed positioning which the arms are non-perpendicular to the shaft, the arms having needle receiving portions; and needles advanceable longitudinally along the shaft toward the needle receiving portions, the needles exiting through side walls of the shaft at a location proximal to the arms.

公开(公告)号：USD859192S1

公开(公告)日：2019-09-10

申请号：US29670569

申请日：2018-11-16

Applicant: Abbott Laboratories

Designer： Christina A. Barton ,  Rachel Elizabeth Wallace ,  Ami Marie Verhalen ,  Daniel Roger Nett

公开(公告)号：US10401209B2

公开(公告)日：2019-09-03

申请号：US15629495

申请日：2017-06-21

Applicant: Abbott Laboratories

Inventor： Lyle Yarnell ,  Michael Shawn Murphy

IPC: G01F23/28 ,  G01F23/00 ,  G01N35/10 ,  H04B1/03 ,  G01N1/14

Abstract: Liquid level sensing apparatus are disclosed. An example liquid level sensing apparatus includes a cannula defining a body having a tip and an access channel. The tip to pierce a container, where the cannula is to be at least partially positioned in the container when the tip pierces the container. A probe is to be positioned in the access channel. A signal source is to electrically energize the probe and the cannula to cause the probe to emit a first signal and cause the cannula to emit a second signal.