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公开(公告)号:US11942318B2
公开(公告)日:2024-03-26
申请号:US16919460
申请日:2020-07-02
Applicant: SHIMADZU CORPORATION
Inventor: Vyacheslav Shchepunov
CPC classification number: H01J49/4245 , H01J49/061 , H01J49/062 , H01J49/401 , H01J49/403 , H01J49/408
Abstract: A mass analyser for use in a mass spectrometer, the mass analyser having: a set of sector electrodes spatially arranged to provide an electrostatic field in a 2D reference plane suitable for guiding ions along an orbit in the 2D reference plane, wherein the set of sector electrodes extend along a drift path that is locally orthogonal to the reference plane so that, in use, the set of sector electrodes provide a 3D electrostatic field region; and an injection interface configured to inject ions into the mass analyser via an injection opening such that the ions injected into the mass analyser are guided by the 3D electrostatic field region along a 3D reference trajectory according to which ions perform multiple turns within the mass analyser whilst drifting along the drift path, wherein each turn corresponds to a completed orbit in the 2D reference plane. The injection interface includes at least one injection deflector located within the mass analyser, the at least one injection deflector being configured to deflect ions injected into the mass analyser in the direction of the drift path, wherein the injection interface is preferably configured so that ions guided along the 3D reference trajectory are, after injection into the mass analyser, kept adequately distant from the injection opening such that they are substantially unaffected by electric field distortions around the injection opening.
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公开(公告)号:US20240047189A1
公开(公告)日:2024-02-08
申请号:US18048049
申请日:2022-10-20
Applicant: CMP Scientific Corp.
Inventor: Paul Nurmi , Joshua Wiley , Qiangwei Xia
CPC classification number: H01J49/067 , H01J49/061 , H01J49/26
Abstract: Systems and methods for analyzing samples are provided. In some embodiments, a mass spectrometer may include a source configured to output a plurality of particles, a tube having a central axis, and a skimmer. In some embodiments, the skimmer may include an aperture arranged to receive the one or more charged particles deflected by a deflector and a contact surface comprising an intersection point that intersects the central axis of the tube. The intersection point may be spaced from the aperture by a distance of at least 5 mm.
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公开(公告)号:US11842892B2
公开(公告)日:2023-12-12
申请号:US17724219
申请日:2022-04-19
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor: Mikhail Belov , Eduard Denisov , Gregor Quiring , Dmitry Grinfeld
CPC classification number: H01J49/4245 , H01J49/061 , H01J49/063 , H01J49/4295
Abstract: Ions are injected into an orbital electrostatic trap. An ejection potential is applied to an ion storage device, to cause ions stored in the ion storage device to be ejected towards the orbital electrostatic trap. Synchronous injection potentials are applied to a central electrode of the orbital electrostatic trap and a deflector electrode associated with the orbital electrostatic trap, to cause the ions ejected from the ion storage device to be captured by the electrostatic trap such that they orbit the central electrode. Application of the ejection potential and application of the synchronous injection potentials are each started at respective different times, the difference in times being selected based on desired values of mass-to-charge ratios of ions to be captured by the orbital electrostatic trap.
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公开(公告)号:US11817303B2
公开(公告)日:2023-11-14
申请号:US16636877
申请日:2018-07-26
Applicant: Micromass UK Limited
Inventor: Anatoly Verenchikov , Mikhail Yavor
CPC classification number: H01J49/403 , H01J49/0031 , H01J49/025 , H01J49/061 , H01J49/164 , H01J49/401 , H01J49/405 , H01J49/406 , H01J49/4245
Abstract: Improved pulsed ion sources and pulsed converters are proposed for multi-pass time-of-flight mass spectrometer, either multi-reflecting (MR) or multi-turn (MT) TOF. A wedge electrostatic field (45) is arranged within a region of small ion energy for electronically controlled tilting of ion packets (54) time front. Tilt angle γ of time front (54) is strongly amplified by a post-acceleration in a flat field (48). Electrostatic deflector (30) downstream of the post-acceleration (48) allows denser folding of ion trajectories, whereas the injection mechanism allows for electronically adjustable mutual compensation of the time front tilt angle, i.e. γ=0 for ion packet in location (55), for curvature of ion packets, and for the angular energy dispersion. The arrangement helps bypassing accelerator (40) rims, adjusting ion packets inclination angles α2 and what is most important, compensating for mechanical misalignments of the optical components.
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公开(公告)号:US11796504B2
公开(公告)日:2023-10-24
申请号:US17399629
申请日:2021-08-11
Applicant: Battelle Memorial Institute
Inventor: Yehia M. Ibrahim , Adam L. Hollerbach , Ailin Li
IPC: G01N27/622 , H01J49/06 , H01J49/42 , G01N27/68
CPC classification number: G01N27/622 , H01J49/061 , H01J49/062 , H01J49/4225 , G01N27/68
Abstract: An apparatus includes multiple levels of ion transport channels, with successive levels coupled by elevator channels. Efficient three dimensional packing provides long path lengths in practical volumes for ion mobility separation with high resolving power. Disclosed elevator configurations provide efficient routing of ion transport channels across levels with low ion loss, enabling ion mobility separation over 100 levels or more. Elevator configurations include (i) opposed traveling waves meeting at an elevator entrance, (ii) external elevator with a wrap-around electrode bank, (iii) external elevator with electrode banks on parallel extension plates, or (iv) elevator operating in surfing mode, in various combinations. Manufacture is aided by printed wiring boards, with interchangeable boards. Assembly with motherboard, spacer block(s), and alignment pins provides efficient distribution of electrode excitations and accurate reproducible positioning.
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公开(公告)号:US20230170205A1
公开(公告)日:2023-06-01
申请号:US17925644
申请日:2021-05-17
Inventor: Hung Quang Hoang , Tom Wirtz , Rathaiah Pureti , Olivier Bouton
CPC classification number: H01J49/421 , H01J49/0031 , H01J49/061
Abstract: A detection apparatus and method for detecting charged particles. The device relies on a detection assembly comprising microchannel plates. The useful surface of the microchannel plate device is maximized in time through the use of beam deflection means upstream of the detection front.
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公开(公告)号:US20230170203A1
公开(公告)日:2023-06-01
申请号:US18053916
申请日:2022-11-09
Applicant: Micromass UK Limited
Inventor: Kevin Giles , David J. Langridge , Jason Lee Wildgoose
IPC: H01J49/06 , H01J49/42 , G01N27/623 , G01N27/622 , H01J49/00
CPC classification number: H01J49/062 , H01J49/422 , G01N27/623 , G01N27/622 , H01J49/061 , H01J49/0031 , H01J49/408
Abstract: A method of introducing and ejecting ions from an ion entry/exit device (4) is disclosed. The ion entry/exit device (4) has at least two arrays of electrodes (20,22). The device is operated in a first mode wherein DC potentials are successively applied to successive electrodes of at least one of the electrode arrays ((20,22) in a first direction such that a potential barrier moves along the at least one array in the first direction and drives ions into and/or out of the device in the first direction. The device is also operated in a second mode, wherein DC potentials are successively applied to successive electrodes of at least one of the electrode arrays (20,22) in a second, different direction such that a potential barrier moves along the array in the second direction and drives ions into and/or out of the device in the second direction. The device provides a single, relatively simple device for manipulating ions in multiple directions. For example, the device may be used to load ions into or eject ions from an ion mobility separator in a first direction, and may then be used to cause ions to move through the ion mobility separator in the second direction so as to cause the ions to separate.
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公开(公告)号:US20230143849A1
公开(公告)日:2023-05-11
申请号:US18149468
申请日:2023-01-03
Applicant: Micromass UK Limited
Inventor: Zoltán TAKÁTS , Frances BOLT , Tamás KARANCSI , Emrys JONES , Keith RICHARDSON , Lajos GODORHAZY , Daniel SZALAY , Julia BALOG , Steven Derek PRINGLE , Daniel SIMON
IPC: H01J49/04 , A61B10/02 , A61B17/32 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/68 , H01J49/00 , H01J49/06 , H01J49/16 , G01N27/623 , A61B90/13 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B17/00 , A61B18/04 , A61B18/18 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N27/624 , G01N30/72 , G01N33/487 , G01N33/92 , H01J49/02 , H01J49/10 , H01J49/14 , H01J49/24 , H01J49/26
CPC classification number: H01J49/049 , A61B10/0233 , A61B10/0283 , A61B17/320068 , A61B18/00 , A61B18/14 , A61B18/20 , G01N3/00 , G01N9/00 , G01N33/6848 , H01J49/0036 , H01J49/0404 , H01J49/0459 , H01J49/068 , H01J49/16 , H01J49/044 , G01N27/623 , A61B90/13 , A61B1/041 , A61B1/2736 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B17/00 , A61B18/04 , A61B18/042 , A61B18/1445 , A61B18/1815 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/6851 , G01N33/92 , H01J49/0004 , H01J49/0027 , H01J49/0031 , H01J49/025 , H01J49/0409 , H01J49/0422 , H01J49/0445 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/10 , H01J49/14 , H01J49/164 , H01J49/24 , H01J49/26 , G16B20/00
Abstract: A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.
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公开(公告)号:US20180286655A1
公开(公告)日:2018-10-04
申请号:US15518408
申请日:2015-10-07
Inventor: Chang Joon Park , Sang Jung AHN , Cheolsu HAN , Keu Chan LEE , Seok Rae YOON
CPC classification number: H01J49/147 , G01N27/62 , H01J49/0031 , H01J49/009 , H01J49/0095 , H01J49/061 , H01J49/4225
Abstract: The present invention relates to a particle beam mass spectrometer and particle measurement method by means of same. More particularly, the present invention relates to a particle beam mass spectrometer including: a particle focusing unit focusing a particle beam induced by gas flow; an electron gun forming a charged particle beam by accelerating thermal electrons to ionize the particle beam focused by the particle focusing unit; a deflector deflecting the charged particle beam according to kinetic energy to charge ratio; and a sensing unit measuring a current induced by the deflected charged particle beam, wherein the deflector includes at least one particle beam separation electrode provided at each of opposite sides with respect to a progress axis of the charged particle beam before being deflected.
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公开(公告)号:US20180218894A1
公开(公告)日:2018-08-02
申请号:US15417767
申请日:2017-01-27
Inventor: Alexandre Likhanskii
CPC classification number: H01J49/22 , H01J49/061
Abstract: An apparatus which has the capability of filtering unwanted species from an extracted ion beam without the use of a mass analyzer magnet is disclosed. The apparatus includes an ion source having chamber walls that are biased by an RF voltage. The use of RF extraction causes ions to exit the ion source at different energies, where the energy of each ion species is related to its mass. The extracted ion beam can then be filtered using only electrostatic energy filters to eliminate the unwanted species. The electrostatic energy filter may act as a high pass filter, allowing ions having an energy above a certain threshold to reach the workpiece. Alternatively, the electrostatic energy filter may act as a low pass filter, allowing ions having an energy below a certain threshold to reach the workpiece. In another embodiment, the electrostatic energy filter operates as a bandpass filter.
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