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Patent Agency Ranking
公开(公告)号：US20210109076A1
公开(公告)日：2021-04-15
申请号：US17128270
申请日：2020-12-21
Applicant: DOTS Technology Corp.
Inventor： Adi Gilboa-Geffen , Renuka Babu Brown , Sarah Stidham , Valerie Villareal , Adam J. Young , Joshua Glenn Anthony , Patrick Murphy , John H. Kepler , Adam Jacobs
Abstract: The present invention provides systems, devices, signaling polynucleotides (SPNs), detection agents and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sampler, at least one disposable detection vessel for receiving and processing a test sample and a detection device for measuring a fluorescent signal. SPNs derived from aptamer that bind allergens are provided as detection agents. SPNs have a single open structure, and are labeled with a fluorophore. Changes in fluorescence polarization of SPNs upon the binding of allergens are measured to calculate the allergen content in a sample.
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公开(公告)号：US10908139B2
公开(公告)日：2021-02-02
申请号：US16084996
申请日：2017-03-10
Applicant: DOTS Technology Corp.
Inventor： Adi Gilboa-Geffen , Renuka Babu Brown , Sarah Stidham , Valerie Villareal , Adam J. Young , Joshua Glenn Anthony , Patrick Murphy , John H. Kepler , Adam Jacobs
IPC: B01L3/00 , B01L1/00 , G01N33/02 , C12M1/34 , G01N1/08 , C12N15/115 , G01N1/14 , G01N1/28 , G01N33/53 , G01N33/58
Abstract: The present invention provides systems, devices, signaling polynucleotides (SPNs), detection agents and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sampler, at least one disposable detection vessel for receiving and processing a test sample and a detection device for measuring a fluorescent signal. SPNs derived from aptamer that bind allergens are provided as detection agents. SPNs have a single open structure, and are labeled with a fluorophore. Changes in fluorescence polarization of SPNs upon the binding of allergens are measured to calculate the allergen content in a sample.
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公开(公告)号：US20210016269A1
公开(公告)日：2021-01-21
申请号：US17063067
申请日：2020-10-05
Applicant: DOTS Technology Corp.
Inventor： Adi Gilboa-Geffen , Renuka Babu Brown , John H. Kepler , Gaurav Rohatgi , Philip Charles Walker , Mark Bates , Christopher James Page
Abstract: The present invention provides systems, devices and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sample pickup, one or more disposables for receiving and processing a test sample and a detection device that can execute an allergen detection testing in minutes. The present detection system and device is compact and portable.
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公开(公告)号：US20190079063A1
公开(公告)日：2019-03-14
申请号：US16084996
申请日：2017-03-10
Applicant: DOTS Technology Corp.
Inventor： Adi Gilboa-Geffen , Renuka Babu Brown , Sarah Stidham , Valerie Villareal , Adam J. Young , Joshua Glenn Anthony , Patrick Murphy , John H. Kepler , Adam Jacobs
Abstract: The present invention provides systems, devices, signaling polynucleotides (SPNs), detection agents and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sampler, at least one disposable detection vessel for receiving and processing a test sample and a detection device for measuring a fluorescent signal. SPNs derived from aptamer that bind allergens are provided as detection agents. SPNs have a single open structure, and are labeled with a fluorophore. Changes in fluorescence polarization of SPNs upon the binding of allergens are measured to calculate the allergen content in a sample.
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公开(公告)号：US20180154350A1
公开(公告)日：2018-06-07
申请号：US15705328
申请日：2016-03-15
Applicant: DOTS Technology Corp.
Inventor： Adi Gilboa-Geffen , Renuka Babu Brown , John H. Kepler , Gaurav Rohatgi , Philip Charles Walker , Mark Bates , Christopher James Page
CPC classification number: B01L3/502 , B01L2200/025 , B01L2200/026 , B01L2200/0605 , B01L2200/0689 , B01L2300/042 , B01L2300/047 , B01L2300/0609 , B01L2300/0654 , B01L2300/0681 , B01L2300/0867 , B01L2300/1822 , B01L2300/1827 , B01L2400/0487 , B01L2400/049 , B01L2400/0694 , C12Q1/6804 , G01N1/08 , G01N1/286 , G01N33/02 , G01N33/5308 , G01N2001/2866 , C12Q2525/205 , C12Q2563/107 , C12Q2565/1015 , C12Q2565/107
Abstract: The present invention provides systems, devices and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sample pickup, one or more disposables for receiving and processing a test sample and a detection device that can execute an allergen detection testing in minutes. The present detection system and device is compact and portable.
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