公开(公告)号：US12076444B2

公开(公告)日：2024-09-03

申请号：US18152394

申请日：2023-01-10

Applicant: Purdue Research Foundation

Inventor： Arun V. Giridhar ,  Michael Harris ,  Gintaras V. Reklaitis ,  Lynne S. Taylor ,  Zoltan K. Nagy ,  Elcin Icten ,  Frederick Fiesser ,  Laura Hirshfield

IPC: A61K9/70 ,  A61K31/167 ,  A61K31/192 ,  A61K31/196 ,  A61K31/415 ,  A61K31/635 ,  A61K47/10 ,  A61K47/14 ,  A61K47/34 ,  A61K47/38 ,  B01J4/00 ,  B01J4/02

CPC classification number: A61K9/7007 ,  A61K31/167 ,  A61K31/192 ,  A61K31/196 ,  A61K31/415 ,  A61K31/635 ,  A61K47/10 ,  A61K47/14 ,  A61K47/34 ,  A61K47/38 ,  B01J4/002 ,  B01J4/008 ,  B01J4/02 ,  B01J2204/005 ,  B01J2204/007

Abstract: Systems and methods for delivering active ingredients, such as pharmaceutically active ingredients, to substrates are described herein. The active ingredients are delivered as fluids to a fluid-dispensing device for the creation of one or more drops for deposition onto substrates such as for the creation of microdoses. The invention further includes microdoses made by such processes.

公开(公告)号：US11781081B1

公开(公告)日：2023-10-10

申请号：US17318533

申请日：2021-05-12

Applicant: Streamline Innovations, Inc.

Inventor： Peter J Photos ,  Franklin Hailey Brown, II ,  David Sisk ,  Benjamin Isaac Tyler ,  Michael A Pue

IPC: C10L3/10 ,  B01D19/00 ,  B01J19/00

CPC classification number: C10L3/103 ,  B01D19/0042 ,  B01D19/0063 ,  B01D19/0068 ,  B01J19/0053 ,  B01J2204/005 ,  B01J2219/00182 ,  B01J2219/00243 ,  B01J2219/185 ,  C10L2290/54

Abstract: An oxidation-reduction desulfurization system includes a reactor vessel with sour gas inlet at the bottom and a gas outlet at the top. A primary stage phase separator includes a vertically-oriented pipe with an inlet located inside the reactor vessel. The ratio of the reactor vessel diameter to the pipe inlet diameter is in a range of 2:1 to 5:1. Surface foam and non-gaseous multi-phase mixture including emulsion flow into a partially gas-filled upper section of the vertically-oriented pipe and freefall to a lower level, thereby facilitating mechanical breaking of the foam and the emulsion. A secondary stage phase separator connected to the gas outlet separates non-gaseous surge from sweet gas. Valves and a controller automatically maintain target levels of the non-gaseous multi-phase mixture and non-gaseous surge.

公开(公告)号：US20230167043A1

公开(公告)日：2023-06-01

申请号：US17910299

申请日：2020-05-28

Applicant: NANJING YANCHANG REACTION TECHNOLOGY RESEARCH INSTITUTE CO., LTD.

Inventor： Zhibing ZHANG ,  Zheng ZHOU ,  Feng ZHANG ,  Lei LI ,  Weimin MENG ,  Baorong WANG ,  Gaodong YANG ,  Huaxun LUO ,  Guoqiang YANG ,  Hongzhou TIAN ,  Yu CAO

IPC: C07C51/265 ,  B01D3/14 ,  B01D5/00 ,  B01J10/00 ,  B01J19/24 ,  B01J4/00

CPC classification number: C07C51/265 ,  B01D3/14 ,  B01D5/0063 ,  B01J10/002 ,  B01J19/245 ,  B01J4/001 ,  B01J2204/002 ,  B01J2204/005

Abstract: The invention provides a built-in micro-interface oxidation system for preparing terephthalic acid from p-xylene. The oxidation system includes a first reactor, a rectifying tower and a second reactor which are sequentially connected. A first outlet is disposed on a side wall of the first reactor; a first inlet is disposed on a side wall of the second reactor; a material inlet is disposed on a side wall of the rectifying tower; and a material outlet is disposed at a bottom of the rectifying tower. The first outlet is connected with the material inlet of the rectifying tower; the first inlet is connected with the material outlet of the rectifying tower. Micro-interface units are arranged in the first reactor and the second reactor for dispersing and crushing air into bubbles. Through disposing micro-interface units in reactors, problems of high energy consumption, high raw material consumption and low reaction efficiency are solved.

公开(公告)号：US20190010260A1

公开(公告)日：2019-01-10

申请号：US15752509

申请日：2016-07-27

Applicant: ExxonMobil Chemical Patents Inc.

Inventor： Henri A. Lammens ,  Paul J. Clymans ,  Cindy Dewitte

IPC: C08F210/02 ,  B01J3/04 ,  B01J3/03 ,  B01J19/06 ,  B01J19/00

CPC classification number: C08F210/02 ,  B01J3/03 ,  B01J3/04 ,  B01J4/008 ,  B01J19/0013 ,  B01J19/002 ,  B01J19/06 ,  B01J19/2415 ,  B01J2204/005 ,  B01J2219/00006 ,  B01J2219/00094 ,  B01J2219/0015 ,  B01J2219/00159 ,  B01J2219/00162 ,  B01J2219/00259 ,  B01J2219/0027 ,  C08F2/34 ,  Y02P30/48

Abstract: This disclosure relates to systems and processes for cooling polymer product mixtures manufactured at high pressure. The processes of the invention involve cooling and then subsequently reducing the pressure of the product mixture from the reactor. In the systems of the invention, a product cooler is located downstream of the high pressure reactor and upstream of a high pressure let down valve.

公开(公告)号：US20180345238A1

公开(公告)日：2018-12-06

申请号：US15776830

申请日：2016-12-02

Applicant: NOVA Chemicals (International) S.A.

Inventor： Teresa Yuk Woon Leung ,  Kamal Kamel Botros ,  Ross Donald Moreton ,  Benjamin Milton Shaw

IPC: B01J3/02 ,  B01J4/00 ,  B01J12/02 ,  B01J19/24 ,  C08F2/01

CPC classification number: B01J3/02 ,  B01J4/007 ,  B01J4/008 ,  B01J12/02 ,  B01J19/2415 ,  B01J2204/005 ,  B01J2204/007 ,  B01J2219/00051 ,  B01J2219/00081 ,  B01J2219/00162 ,  B01J2219/00166 ,  B01J2219/00245 ,  B01J2219/0027 ,  C08F2/01

Abstract: Provided herein is a unidirectional blow down system for a high-pressure tubular reactor with a hyper that minimizes the tube wall metal temperature during a decomposition event wherein the system prevents the reactor walls from reaching a temperature capable of causing the tube metal to austenize. Also provided are methods of designing and methods of operating a unidirectional blowdown system.

公开(公告)号：US20180257055A1

公开(公告)日：2018-09-13

申请号：US15762377

申请日：2016-08-10

Applicant: ExxonMobil Chemical Patents Inc.

Inventor： Philip H. Cornelissen ,  Paul J. Clymans ,  Henri A. Lammens

IPC: B01J19/00 ,  C08F10/02 ,  B01J4/00 ,  B01J19/24

CPC classification number: B01J19/002 ,  B01J4/008 ,  B01J19/24 ,  B01J19/2415 ,  B01J2204/005 ,  B01J2219/00006 ,  B01J2219/00094 ,  B01J2219/00159 ,  B01J2219/00162 ,  B01J2219/00259 ,  B01J2219/0027 ,  C08F10/00 ,  C08F10/02 ,  C08F2/00 ,  C08F4/34

Abstract: Systems and processes for rapidly depressurizing a reactor system are disclosed. The systems and processes are particularly useful in the high pressure polymerization of ethylene.

公开(公告)号：US20180079972A1

公开(公告)日：2018-03-22

申请号：US15558614

申请日：2016-03-17

Applicant: DONALDSON COMPANY, INC.

Inventor： Davis B. Moravec ,  Andrew J. Dallas ,  Joseph M. Block ,  Bradly G. Hauser ,  Cullen E. Hall ,  Mark C. Shepherd ,  Mike J. Madsen

IPC: C10G33/06 ,  C10G33/08 ,  B01D61/10 ,  B01D15/36 ,  B01J20/20 ,  B01J20/28 ,  B01J41/05 ,  C02F1/42 ,  C02F1/28

CPC classification number: C10G33/06 ,  B01D15/363 ,  B01D61/10 ,  B01J20/20 ,  B01J20/261 ,  B01J20/262 ,  B01J20/28033 ,  B01J20/28045 ,  B01J20/2805 ,  B01J41/05 ,  B01J2204/005 ,  B01J2220/46 ,  B01J2220/48 ,  B01J2220/50 ,  C02F1/008 ,  C02F1/28 ,  C02F1/283 ,  C02F1/285 ,  C02F1/42 ,  C02F2001/422 ,  C02F2101/32 ,  C02F2103/365 ,  C02F2209/005 ,  C02F2209/44 ,  C02F2209/445 ,  C02F2301/08 ,  C10G33/08

Abstract: A hydrocarbon-in-water purification system includes a high capacity hydrocarbon absorber stage having a high capacity hydrocarbon absorber material and an inlet configured to receive a hydrocarbon-in-water dispersion from a fuel system. A polishing hydrocarbon absorber stage is in liquid communication and downstream of the high capacity hydrocarbon absorber stage including polishing activated carbon. The high capacity hydrocarbon absorber material has a greater saturation capacity than the polishing activated carbon and the polishing activated carbon has a greater polishing capacity than the high capacity hydrocarbon absorber material. A method for controlling and managing the evacuation of water from the hydrocarbon-in-water purification system includes tracking the purification state of water volumes and the bed loading states of purification beds defined in the water filter.

公开(公告)号：US20170226152A1

公开(公告)日：2017-08-10

申请号：US15299931

申请日：2016-10-21

Applicant: CEM Corporation

Inventor： JONATHAN M. COLLINS

IPC: C07K1/04 ,  C07K1/14 ,  C07K1/06 ,  C07K14/575 ,  C07K14/605 ,  C07K14/815 ,  C07K14/635 ,  C07K14/59 ,  C07K14/705 ,  C07K14/645 ,  C07K14/005 ,  C12N7/00 ,  C07K14/47 ,  C07K7/08 ,  C07K7/16 ,  C07K14/46 ,  B01J19/12 ,  C07K1/107

CPC classification number: C07K1/045 ,  B01J19/126 ,  B01J2204/005 ,  B01J2219/00058 ,  B01J2219/0879 ,  B01J2219/1248 ,  C07K1/04 ,  C07K1/063 ,  C07K1/1075 ,  C07K1/14 ,  C07K7/08 ,  C07K7/16 ,  C07K14/005 ,  C07K14/463 ,  C07K14/4701 ,  C07K14/4723 ,  C07K14/575 ,  C07K14/57572 ,  C07K14/59 ,  C07K14/605 ,  C07K14/635 ,  C07K14/645 ,  C07K14/705 ,  C07K14/815 ,  C12N7/00 ,  C12N2740/16322

Abstract: An improved method of deprotection in solid phase peptide synthesis is disclosed. In particular the deprotecting composition is added in high concentration and small volume to the mixture of the coupling solution, the growing peptide chain, and any excess activated acid from the preceding coupling cycle, and without any draining step between the coupling step of the previous cycle and the addition of the deprotection composition for the successive cycle. Thereafter, the ambient pressure in the vessel is reduced with a vacuum pull to remove the deprotecting composition without any draining step and without otherwise adversely affecting the remaining materials in the vessel or causing problems in subsequent steps in the SPPS cycle.

公开(公告)号：US20120227822A1

公开(公告)日：2012-09-13

申请号：US13496484

申请日：2010-09-10

Applicant: Leonard James Humphreys

Inventor： Leonard James Humphreys

IPC: B01J19/00 ,  F17D3/00

CPC classification number: B01J3/008 ,  B01J4/002 ,  B01J4/008 ,  B01J2204/005 ,  B01J2208/00212 ,  B01J2208/00539 ,  B01J2208/0061 ,  C10L9/086 ,  Y02P20/544 ,  Y10T137/0379

Abstract: An assembly (10) for reducing pressure of slurry exiting an outlet pipe (15) of a supercritical reactor (116), the assembly (10) including a sealed collection vessel (12) and an orifice assembly (14) forming an inlet of the collection vessel (12), wherein the orifice assembly (14) comprises a plurality of orifices (17 to 20) for parallel connection with the reactor outlet pipe (15) such that flow from the outlet pipe (15) can be directed to any one of the orifices (17 to 20).

Abstract translation: 一种用于减少离开超临界反应器（116）的出口管（15）的浆料的压力的组件（10），所述组件（10）包括密封的收集容器（12）和形成所述超临界反应器的入口的孔组件（14） 收集容器（12），其中所述孔口组件（14）包括多个与所述反应器出口管（15）并联连接的孔口（17至20），使得来自所述出口管道（15）的流动可以被引导到任何一个 的孔（17至20）。

公开(公告)号：US20110152564A1

公开(公告)日：2011-06-23

申请号：US12946382

申请日：2010-11-15

Applicant: Shuzo FUJIWARA ,  Yasuhide SUZUKI ,  Yasuhiko OKUDA ,  Tetsuya HIROSE

Inventor： Shuzo FUJIWARA ,  Yasuhide SUZUKI ,  Yasuhiko OKUDA ,  Tetsuya HIROSE

IPC: C07C69/76 ,  B01J19/00 ,  C07C69/604 ,  C07C69/753

CPC classification number: B01J10/005 ,  B01F7/00208 ,  B01F7/161 ,  B01F7/18 ,  B01J4/007 ,  B01J19/0013 ,  B01J19/002 ,  B01J19/0066 ,  B01J19/18 ,  B01J2204/005 ,  B01J2219/00094 ,  B01J2219/00254 ,  B01J2219/00779 ,  C09J133/06

Abstract: A resin production apparatus of the present invention includes: a reactor vessel having a vessel main body which polymerizes an ingredient to produce a thermoplastic synthetic resin which solidifies at room temperature and storing the synthetic resin in the molten state, an output mechanism disposed at a bottom part of the vessel main body, which outputs the synthetic resin in the molten state, and a temperature adjustment mechanism which adjusts temperatures of the vessel main body and the output mechanism so as to maintain the molten state of the synthetic resin; a cooling mechanism arranged below the reactor vessel, which continuously cools and solidifies the synthetic resin output from the output mechanism; and a crushing mechanism which crushes the synthetic resin fed out from the cooling mechanism.

Abstract translation: 本发明的树脂制造装置包括：反应容器，其具有容器主体，聚合成分以制备在室温下固化并将合成树脂储存在熔融状态的热塑性合成树脂，输出机构设置在底部 输出熔融状态的合成树脂的容器主体的一部分，以及调节容器主体和输出机构的温度以保持合成树脂的熔融状态的温度调节机构; 布置在反应器下方的冷却机构，其连续地冷却并固化从输出机构输出的合成树脂; 以及粉碎从冷却机构送出的合成树脂的破碎机构。