公开(公告)号：DE59209064D1

公开(公告)日：1998-01-22

申请号：DE59209064

申请日：1992-09-23

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  KOERWER WOLFGANG ,  KROEGER BURKHARD ,  BIALOJAN SIEGFRIED

IPC: A61K35/64 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  C07K1/14 ,  C07K14/435 ,  C07K14/81 ,  C12N15/09 ,  C12N15/15 ,  C12P21/02

Abstract: PCT No. PCT/EP92/02198 Sec. 371 Date Mar. 18, 1994 Sec. 102(e) Date Mar. 18, 1994 PCT Filed Sep. 23, 1992 PCT Pub. No. WO93/09231 PCT Pub. Date May 13, 1993A novel thrombin inhibitory protein from ticks with a molecular weight of about 26000 dalton and the partial amino acid sequences Val-Ala-Lys-Phe-Ala-X-Asn-Ser-Gly-Ser-Glu-Thr-Gly (SEQ ID NO: 8), His-Ala-Y-Phe-Glu (SEQ ID NO: 3), Arg-Val-Ser-Asp-Phe-Glu (SEQ ID NO: 4), Phe-Val-Tyr-Thr-Ile-Glu (SEQ ID NO: 6), where X and Y can be identical or different and each is a naturally occurring amino acid, is suitable for controlling diseases.

公开(公告)号：AT161046T

公开(公告)日：1997-12-15

申请号：AT92920588

申请日：1992-09-23

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  KOERWER WOLFGANG ,  KROEGER BURKHARD ,  BIALOJAN SIEGFRIED

IPC: A61K35/64 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  C07K1/14 ,  C07K14/435 ,  C07K14/81 ,  C12N15/09 ,  C12N15/15 ,  C12P21/02

Abstract: PCT No. PCT/EP92/02198 Sec. 371 Date Mar. 18, 1994 Sec. 102(e) Date Mar. 18, 1994 PCT Filed Sep. 23, 1992 PCT Pub. No. WO93/09231 PCT Pub. Date May 13, 1993A novel thrombin inhibitory protein from ticks with a molecular weight of about 26000 dalton and the partial amino acid sequences Val-Ala-Lys-Phe-Ala-X-Asn-Ser-Gly-Ser-Glu-Thr-Gly (SEQ ID NO: 8), His-Ala-Y-Phe-Glu (SEQ ID NO: 3), Arg-Val-Ser-Asp-Phe-Glu (SEQ ID NO: 4), Phe-Val-Tyr-Thr-Ile-Glu (SEQ ID NO: 6), where X and Y can be identical or different and each is a naturally occurring amino acid, is suitable for controlling diseases.

公开(公告)号：DK0612349T3

公开(公告)日：1997-07-28

申请号：DK92922434

申请日：1992-10-27

Applicant: BASF AG

Inventor： BIALOJAN SIEGFRIED ,  FRIEDRICH THOMAS ,  KUENAST CHRISTOPH ,  KROEGER BURKHARD

IPC: A61K35/64 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  C07K14/00 ,  C07K14/245 ,  C07K14/435 ,  C07K14/81 ,  C12N15/15 ,  C12P21/02 ,  C12R1/19 ,  A61K37/64 ,  C07K13/00

Abstract: PCT No. PCT/EP92/02450 Sec. 371 Date Apr. 26, 1994 Sec. 102(e) Date Apr. 26, 1994 PCT Filed Oct. 27, 1992 PCT Pub. No. WO93/09232 PCT Pub. Date May 13, 1993.A novel thrombin-inhibitory protein from assassin bugs with a molecular weight of about 12,000 dalton and the N terminus Glu-Gly-Gly-Glu-Pro-Cys-Ala-Cys-Pro-His-Ala-Leu-His-Arg-Val-Cys-Gly-Ser-Asp is described. The protein is suitable for controlling diseases.

公开(公告)号：ES2097931T3

公开(公告)日：1997-04-16

申请号：ES92922434

申请日：1992-10-27

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  BIALOJAN SIEGFRIED ,  KROEGER BURKHARD ,  KUENAST CHRISTOPH

IPC: A61K35/64 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  C07K14/00 ,  C07K14/245 ,  C07K14/435 ,  C07K14/81 ,  C12N15/15 ,  C12P21/02 ,  C12R1/19

Abstract: PCT No. PCT/EP92/02450 Sec. 371 Date Apr. 26, 1994 Sec. 102(e) Date Apr. 26, 1994 PCT Filed Oct. 27, 1992 PCT Pub. No. WO93/09232 PCT Pub. Date May 13, 1993.A novel thrombin-inhibitory protein from assassin bugs with a molecular weight of about 12,000 dalton and the N terminus Glu-Gly-Gly-Glu-Pro-Cys-Ala-Cys-Pro-His-Ala-Leu-His-Arg-Val-Cys-Gly-Ser-Asp is described. The protein is suitable for controlling diseases.

公开(公告)号：MX9205978A

公开(公告)日：1993-04-01

申请号：MX9205978

申请日：1992-10-16

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  BIALOJAN SIEGFRIED ,  BOLLSCHWEILER CLAUS ,  KUENAST CHRISTOPH

IPC: A61K35/64 ,  A61K38/00 ,  A61K38/55 ,  A61P7/02 ,  C07K14/435 ,  C07K14/81 ,  C12N15/09 ,  C12N15/15 ,  C12P21/02 ,  C12R1/19 ,  C07K13/00

公开(公告)号：HU228092B1

公开(公告)日：2012-10-29

申请号：HU0104802

申请日：1999-10-13

Applicant: BASF AG

Inventor： RESS-LOESCHKE MARION ,  FRIEDRICH THOMAS ,  HAUER BERHARD ,  MATTES RALF ,  ENGELS DIRK

IPC: C12N9/78 ,  C07H21/00 ,  C12N15/09 ,  C12N1/21 ,  C12N15/55 ,  C12N15/63 ,  C12P7/40 ,  C12P7/42 ,  C12P41/00 ,  C12R1/05

Abstract: The invention relates to nucleic acid sequences which code for a polypeptide having nitrilase activity, to nucleic acid constructs comprising the nucleic acid sequences, and to vectors comprising the nucleic acid sequences or the nucleic acid constructs. The invention further relates to amino acid sequences which are encoded by the nucleic acid sequences, and to microorganisms comprising the nucleic acid sequences, the nucleic acid constructs or vectors comprising the nucleic acid sequences or the nucleic acid constructs.The invention additionally relates to a process for preparing chiral carboxylic acids from the racemic nitriles.

公开(公告)号：CZ302494B6

公开(公告)日：2011-06-15

申请号：CZ20011382

申请日：1999-10-13

Applicant: BASF AG

Inventor： RESS-LOESCHKE MARION ,  FRIEDRICH THOMAS ,  HAUER BERNHARD ,  MATTES RALF ,  ENGELS DIRK

IPC: C12N9/78 ,  C12N15/09 ,  C07H21/00 ,  C12N1/21 ,  C12N15/55 ,  C12N15/63 ,  C12P7/40 ,  C12P7/42 ,  C12P41/00 ,  C12R1/05

Abstract: Rešení se týká sekvence nukleových kyselin, která kóduje polypeptid s nitrilázovou aktivitou, konstruktu nukleových kyselin, zahrnujících tuto sekvenci nukleových kyselin a vektoru, zahrnujících tuto sekvenci nukleových kyselin nebo uvedené konstrukty nukleových kyselin. Dále se týká aminokyselinových sekvencí, které jsou kódovány uvedenou sekvencí nukleových kyselin a mikroorganizmu, zahrnujících uvedené sekvence nukleových kyselin, konstrukty nukleových kyselin nebo vektory, obsahující uvedené sekvence nukleových kyselin nebo konstrukty nukleových kyselin. Rešení se rovnež týká zpusobu prípravy chirálních karboxylových kyselin z racemických nitrilu, který využívá pripravenou nitrilázu.

公开(公告)号：CA2683037A1

公开(公告)日：2008-11-06

申请号：CA2683037

申请日：2008-04-25

Applicant: BASF AG

Inventor： DOMBO PETER ,  YAMAMOTO MOTONORI ,  WINTER GABI ,  SZTOJ SILVIA ,  HUBER-MOULLIET URSULA ,  DIECKMANN YVONNE ,  BRANDS MARIO ,  FRIEDRICH THOMAS ,  ISRAELS RAFEL

IPC: A01N25/12 ,  A01N25/10 ,  A01N63/00 ,  A01P13/00 ,  B01J13/02

Abstract: The present invention relates to novel active ingredient compositions for plant protection in the form of fine active ingredient-containing particles , comprising a) at least one active plant protection agent; b) at least one polymer P, which is not soluble in water, can be decomposed by enzymatic hyd rolysis and is present in a quantity of at least 20% by weight, relative to the total amount of the components of the active ingredient-containing parti cles, and c) at least one hydrolase (EC 3), wherein at least 90% by weight o f the active ingredient-containing particles of the active ingredient compos ition does not exceed a diameter of 500 .mu.m (Dgo value), wherein the compo nents a), b) and c) constitute at least 30% by weight of the active ingredie nt particles. The invention further relates to a method for the production t hereof and to the use of the active ingredient compositions for the treatmen t of plants, soils and seed.

公开(公告)号：DE102004060319A1

公开(公告)日：2006-06-22

申请号：DE102004060319

申请日：2004-12-15

Applicant: BASF AG

Inventor： FRIEDRICH THOMAS ,  BOY MATTHIAS ,  STUERMER RAINER

IPC: C08B37/08 ,  A61K38/14 ,  C09K23/34 ,  C12P19/00

Abstract: Preparation of peptidoglycan (I) or its derivatives from gram-positive bacteria comprising isolating (I) from a biomass (A) containing the gram-positive bacteria, where the isolation is carried out in partial stages comprising incubating (A) with a solution (containing at least one detergent) at 20-90[deg]C to obtain a mixture (II) containing solvents, detergents, soluble components, (I) and optionally further solid components, is new. Independent claims are also included for: (1) (I) and its derivative obtained by the method; and (2) a copolymer comprising (I) or one of its derivatives as a monomer unit.

公开(公告)号：CA2110497C

公开(公告)日：2005-04-19

申请号：CA2110497

申请日：1992-06-23

Applicant: BASF AG

Inventor： BRAATZ REINHARD ,  KURTH ROLAND ,  MENKEL-CONEN ELKE ,  RETTENMAIER HANSJOERG ,  FRIEDRICH THOMAS ,  SUBKOWSKI THOMAS

IPC: A61K38/46 ,  A61K38/00 ,  A61P1/00 ,  A61P1/14 ,  C12N1/20 ,  C12N9/20 ,  C12R1/38 ,  G01N33/573

Abstract: Described is the use of a bacterial lipase from Chromobacter viscosum, Pseudomonas cepacia IAM 1057, Pseudomonas fluorescens and Pseudomonas DSM 6535 which shows a positive immunological cross-section to antibodies of the lipase from Pseudomonas spec. DSM 6483. The lipase from Pseudomonas spec. DSM 6535 is used to produce drugs for use in therapy of maldigestion. The lipase is formed from the species Psedomonas spec. DSM 6483 and/or Pseudonomas cepacia IAM 1057.