公开(公告)号：NO932875A

公开(公告)日：1994-02-14

申请号：NO932875

申请日：1993-08-12

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  SANNER AXEL ,  ROSENBERG JOERG

IPC: A01N25/10 ,  A01N25/12 ,  A61K9/14 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K47/38 ,  A61K47/30

CPC classification number: A61K9/146 ,  A61K9/2095

公开(公告)号：BRPI0009299B8

公开(公告)日：2021-07-06

申请号：BRPI0009299

申请日：2000-03-17

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BERNDL GUNTHER ,  LIEPOLD BERND ,  BREITENBACH JOERG

IPC: A61K47/10 ,  A61K9/16 ,  A61K9/20 ,  A61K47/14 ,  A61K47/34 ,  A61P31/10 ,  A61P35/00 ,  A61P37/06 ,  A61P43/00

公开(公告)号：CA2243522C

公开(公告)日：2007-05-22

申请号：CA2243522

申请日：1997-01-17

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K31/19 ,  A61K9/20

Abstract: The invention concerns preparation of non-steroidal analgesics with antipyretic and antiphlogistic effect, obtained through extrusion and moulding of a melt containing in addition one or more substances in a mixture of a) 40 to 99.5 wt% of a homopolymer of N--vinylpyrrolidone with a K value according to Fikentscher of 30; b) 0.25 t o 59.75 wt% of a water-soluble copolymer of N-vinylpyrr olidone; and c) 0.25 to 10 wt% of one or more physiologically ac ceptable sodium- or potassium salts, whee the quantities refer to the total of the components a), b) and c).

公开(公告)号：CA2208722C

公开(公告)日：2006-08-22

申请号：CA2208722

申请日：1995-12-22

Applicant: BASF AG

Inventor： MAIER WERNER ,  BREITENBACH JORG ,  ROSENBERG JOERG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: The invention concerns a method of producing lenticular tablets by melt calendering, using form cylinders provided with ellipsoid-segment recesses. The proposed method produces tablets which are easy to trim and in which any misalignement between the top and bottom halves of the tablet is such that only a small residue needs to be ground off.

公开(公告)号：CA2232356C

公开(公告)日：2005-08-23

申请号：CA2232356

申请日：1996-10-23

Applicant: BASF AG

Inventor： ZETTLER HANS DIETER ,  HOFMANN JURGEN ,  ROSENBERG JOERG ,  HARTL AXEL PAUL ,  BREITENBACH JORG ,  SCHIESSL MICHAEL

IPC: A61J3/10 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K31/07 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/4422 ,  A61K31/52 ,  A61K31/522 ,  A61K31/60 ,  A61K9/02 ,  A61K31/19 ,  A61K31/275 ,  A61K31/40 ,  A61K31/455

Abstract: The invention concerns a method of producing multi-layer medicaments in soli d form for oral or rectal administration. At least two substances, which each comprise a thermoplastic, pharmacologically acceptable polymer binder which is soluble or can swell in a physiological environment, at least one of the substances comprising a pharmaceutical active substance, are coextruded and the coextruded multi-layer material is shaped to form the desired medicament.

公开(公告)号：AT251898T

公开(公告)日：2003-11-15

申请号：AT98104493

申请日：1998-03-12

Applicant: BASF AG

Inventor： ZEIDLER JUERGEN ,  ROSENBERG JOERG ,  BREITENBACH JOERG ,  KLEINKE ANDREAS ,  MAIER WERNER

IPC: A61J3/10 ,  A61K9/20 ,  A61K47/26 ,  A61K47/30 ,  B30B11/16

公开(公告)号：ES2187678T3

公开(公告)日：2003-06-16

申请号：ES96934494

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JURGEN ,  ROSENBERG JOERG ,  NEUMANN JORG ,  BREITENBACH JORG

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients,A) 10-90% by weight of a melt-processable, water-soluble polymer,B) 5-85% by weight of isomalt, andC) 0-5% by weight of lecithin,where the total of all the ingredients is to be equal to 100% by weight.

公开(公告)号：NO20025759A

公开(公告)日：2003-01-14

申请号：NO20025759

申请日：2002-11-29

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  HERR DIETER ,  LAUX VOLKER ,  HEGER ROBERT

IPC: A61K47/12 ,  A61K9/16 ,  A61K31/726 ,  A61K31/727 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K47/44 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  A61P37/06

CPC classification number: A61K9/1635 ,  A61K9/1617 ,  A61K9/1652 ,  A61K31/726 ,  A61K31/727

公开(公告)号：ES2175139T3

公开(公告)日：2002-11-16

申请号：ES96937214

申请日：1996-10-23

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  HARTL AXEL PAUL ,  HOFMANN JURGEN ,  ROSENBERG JOERG ,  SCHIESSL MICHAEL ,  ZETTLER HANS DIETER

IPC: A61J3/10 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K31/07 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/4422 ,  A61K31/52 ,  A61K31/522 ,  A61K31/60

Abstract: PCT No. PCT/EP96/04601 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 23, 1996 PCT Pub. No. WO97/15293 PCT Pub. Date May 1, 1997The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.

公开(公告)号：NO313485B1

公开(公告)日：2002-10-14

申请号：NO964939

申请日：1996-11-20

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG

IPC: A61K9/14 ,  A61K9/20 ,  B01J2/20

Abstract: PCT No. PCT/EP96/01047 Sec. 371 Date Nov. 21, 1996 Sec. 102(e) Date Nov. 21, 1996 PCT Filed Mar. 12, 1996 PCT Pub. No. WO96/29061 PCT Pub. Date Sep. 26, 1996A process for producing active substance compositions in the form of a solid solution of the active substance in a polymer matrix, which comprises melt extrusion of the active substance in nonionic form together with a polymer and a salt.