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    HYDROXYLAMINE DERIVATIVES
    112.
    发明专利
    HYDROXYLAMINE DERIVATIVES 未知

    公开(公告)号：CA2001988C

    公开(公告)日：1999-04-13

    申请号：CA2001988

    申请日：1989-11-01

    Applicant: BASF AG

    Inventor： WILD JOCHEN ,  HARREUS ALBRECHT ,  SCHIRMER ULRICH ,  MEYER NORBERT ,  KAST JUERGEN ,  KOLASSA DIETER

    IPC: C07C239/20 ,  C07C323/19 ,  C07D209/48

    Abstract: Hydroxylamine derivatives have the general formula I Aryl-A-O-B where Aryl is an unsubstituted or substituted, mononuclear or binuclear, isocyclic radical; A is a 1,4-butenylene group of the general formulae IIa or IIb (see fig. I) (see fig. II) where R1, R2, R3, R4 and R5 are each hydrogen, halogen, C1-C6-alkyl or C1-C6-alkenyl; B is NH2 or a dicarboximide group of the general formula III (see fig. III) where Z is unsubstituted or substituted phenylene, naphthylene, pyridinylene, cyclopentylene, cyclohexylene, cyclohexenylene, C2-C4-alkenylene or C2-C4-alkylene.

    Medicinal use of pyrimido:triazine-di:one derivs.
    114.
    发明专利
    Medicinal use of pyrimido:triazine-di:one derivs. 未知

    公开(公告)号：DE19534164A1

    公开(公告)日：1996-04-25

    申请号：DE19534164

    申请日：1995-09-15

    Applicant: BASF AG

    Inventor： ALBRECHT HANS-PETER ,  BOEHM HANS-JOACHIM ,  BRADY KENNETH DALE ,  ECKARD PETER ,  KARDORFF UWE ,  MEYER NORBERT ,  SCHIRMER ULRICH ,  TALANIAN ROBERT VINCENT ,  WALKER NIGEL P C

    IPC: A61K31/53 ,  A61K31/5377 ,  C07D487/04

    Abstract: Pyrimido(5,4-e)-as-triazine-5,7(6H,8H)-dione derivs. of formula (I) and their acid addn. salts are claimed for use in combatting diseases. R , R = H, alkyl, 3-6C cycloalkyl, 2-8C alkenyl, phenyl or benzyl; R = H, halogen or NO2; 1-8C alkyl (opt. substd. by 1-3 of OH, halogen, alkoxy, alkyl, (1-4C)alkoxy(1-4C)alkoxy, 2-6C alkenyl, alkylthio, phenyl and benzyl); 2-6C alkenyl or -phenylalkenyl; 3-6C cycloalkyl (opt. substd. by one to three 1-4C alkyl gps.); 5- or 6-membered heterocycle contg. 1 or 2 of O, S, NR and N as ring members; COR or COOR ; phenyl or monocyclic heteroaryl (both opt. substd. by 1-3 of halogen, NO2, alkyl, 2-6C alkenyl, alkoxy and NR R ); or -ZR ; R , R = H or alkyl; Z = O, S or NR ; R = H or alkyl; or phenyl or benzyl (both opt. ring-substd. by 1-3 of alkyl, alkoxy and halogen); R = H or alkyl; or NR R = 5- or 6-membered ring (opt. interrupted by O); n = 0 or 1; alkyl moieties have 1-6C unless specified otherwise. (I) are known cpds., described in EP407888.

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