MINIATURIZED OPTICAL HEAD WITH HIGH SPATIAL RESOLUTION AND HIGH SENSITIVITY, ESPECIALLY FOR FIBRED CONFOCAL FLUORESCENCE IMAGING

    公开(公告)号:CA2650856A1

    公开(公告)日:2007-11-15

    申请号:CA2650856

    申请日:2007-04-27

    Abstract: The invention concerns a miniaturized optical head provided to equip the distal end of a beam of flexible optical fibres scanned by a laser beam, sai d optical head being designed to come in contact with a sample and to excite said sample confocally; this optical head consisting of means for correctin g spherical aberrations and focusing means. According to the invention, the focusing means comprise: at least a first lens (L4) of high convergence asso ciated with a spherical or hemispherical lens (L5) arranged at the distal en d of the optical head, and means for correction of the axial and lateral chr omatic aberration provided with a single divergent lens (3b) the curvature o f which is substantially centred on the pupil of the optical fibre beam and arranged at the exact distance for this pupil for which the conditions of la teral achromatization coincide with the conditions of axial achromatization; this divergent lens being associated with a second convergent lens (L3a) in the form of a doublet (L3).

    125.
    发明专利
    未知

    公开(公告)号:DE60209942T2

    公开(公告)日:2006-11-30

    申请号:DE60209942

    申请日:2002-12-20

    Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.

    Method for processing an image acquired by means of a guide consisting of a plurality of optical fibres

    公开(公告)号:IL166152D0

    公开(公告)日:2006-01-15

    申请号:IL16615205

    申请日:2005-01-05

    Abstract: A method for processing an image acquired through a guide consisting of a plurality of optical fibers includes, for each optical fiber, isolating on the acquired image a zone corresponding to the optical fiber, locally processing each zone individually to correct the photon flux detected in each optical fiber, then reconstructing the acquired image by eliminating the pattern caused by the optical fiber. The method also includes a sampling process for obtaining, for each optical fiber and from a sampling image, a sample injection rate which can be used for reconstructing the acquired images. The method also includes a prior step which consists in detecting the fibers from a target.

    128.
    发明专利
    未知

    公开(公告)号:DK1468322T3

    公开(公告)日:2005-12-05

    申请号:DK02805803

    申请日:2002-12-20

    Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.

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