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公开(公告)号:FR2865371B1
公开(公告)日:2007-12-21
申请号:FR0400581
申请日:2004-01-22
Applicant: CENTRE NAT RECH SCIENT , OBSERVATOIRE PARIS , MAUNA KEA TECHNOLOGIES
Inventor: LACOMBE FRANCOIS , LAFAILLE DAVID , GLANC MARIE , GENDRON ERIC , STEFANOVITCH DOUCHANE
Abstract: The device includes an active test pattern (MAM), a movable target and a programmable trajectory. The movable target is displayed on a screen of a desktop computer, where the target is visible to an eye of a subject during a testing period. The target is constituted of set of concentric circles and an aiming mark at the center of the circles. Independent claims are also included for the following: (A) a method of sight for testing eye of a subject (B) an eye testing system using tomography in vivo.
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公开(公告)号:CA2650856A1
公开(公告)日:2007-11-15
申请号:CA2650856
申请日:2007-04-27
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: LAVILLONNIERE NICOLAS , DOUSSOUX FRANCOIS , BOULAROT NICOLAS , VIELLEROBE BERTRAND , GENET MAGALIE , MATHIEU GILLES
Abstract: The invention concerns a miniaturized optical head provided to equip the distal end of a beam of flexible optical fibres scanned by a laser beam, sai d optical head being designed to come in contact with a sample and to excite said sample confocally; this optical head consisting of means for correctin g spherical aberrations and focusing means. According to the invention, the focusing means comprise: at least a first lens (L4) of high convergence asso ciated with a spherical or hemispherical lens (L5) arranged at the distal en d of the optical head, and means for correction of the axial and lateral chr omatic aberration provided with a single divergent lens (3b) the curvature o f which is substantially centred on the pupil of the optical fibre beam and arranged at the exact distance for this pupil for which the conditions of la teral achromatization coincide with the conditions of axial achromatization; this divergent lens being associated with a second convergent lens (L3a) in the form of a doublet (L3).
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公开(公告)号:AU2007247033A1
公开(公告)日:2007-11-15
申请号:AU2007247033
申请日:2007-04-27
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: DOUSSOUX FRANCOIS , VIELLEROBE BERTRAND , BOULAROT NICOLAS , MATHIEU GILLES , LAVILLONNIERE NICOLAS , GENET MAGALIE
Abstract: A miniaturized optical head provided to equip the distal end of a beam of flexible optical fibers scanned by a laser beam, is designed to come in contact with a sample and to excite the sample confocally. This optical head includes elements for correcting spherical aberrations and focusing members. The focusing members include: at least a first lens (L4) of high convergence associated with a spherical or hemispherical lens (L5) arranged at the distal end of the optical head, and elements for correcting the axial and lateral chromatic aberration provided with a single divergent lens (3b) whose curvature is substantially centered on the pupil of the optical fiber beam and arranged at the exact distance for this pupil for which the conditions of lateral achromatization coincide with the conditions of axial achromatization; this divergent lens being associated with a second convergent lens (L3a) in the form of a doublet (L3).
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公开(公告)号:CA2647688A1
公开(公告)日:2007-10-25
申请号:CA2647688
申请日:2007-03-23
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: OSDOIT ANNE , LOPEZ JEROME , LOISEAU ALEXANDRE , CAVE CHARLOTTE , VIELLEROBE BERTRAND , ABRAT BENJAMIN
Abstract: L'invention concerne un procédé d'acquisition d'imagerie de fluorescence, in vivo, d'un tissu au moyen d'un système d'acquisition comprenant au moins une fibre optique d'excitation du tissu par balayage d'un faisceau lumineux. Sel on l'invention, on utilise le système pour la détection de signaux de fluorescence émis par du Bleu de Méthylène présent dans le tissu.
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公开(公告)号:DE60209942T2
公开(公告)日:2006-11-30
申请号:DE60209942
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: BERIER FREDERIC , BOURRIAUX STEPHANE , GENET MAGALIE , VIELLEROBE BERTRAND , LOISEAU ALEXANDRE , ABRAT BENJAMIN
Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.
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公开(公告)号:AU2005298494A1
公开(公告)日:2006-05-04
申请号:AU2005298494
申请日:2005-10-21
Applicant: MAUNA KEA TECHNOLOGIES , CENTRE NAT RECH SCIENT , UNIV LIMOGES
Inventor: PAGNOUX DOMINIQUE , LELEK MICKAEL , LOISEAU ALEXANDRE , VIELLEROBE BERTRAND , BARTHELEMY ALAIN , LOURADOUR FREDERIC , LACOMBE FRANCOIS
Abstract: A system for carrying out fibered multiphoton microscopic imagery of a sample (10) for use in endoscopy or fluorescence microscopy includes: a femtosecond pulsed laser (1, 2) for generating a multiphoton excitation laser radiation; an image guide (8) having a number of optical fibers and permitting the sample to be illuminated by a point-by-point scanning in a subsurface plane; pre-compensating elements (4) for pre-compensating for dispersion effects of the excitation pulses in the image guide (8), these elements being situated between the pulsed laser and the image guide (8); scanning elements for directing, in succession, the excitation laser beam in a fiber of the image guide, and; in particular, an optical head (9) for focussing the excitation laser beam exiting the image guide in the sample (10).
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127.
公开(公告)号:IL166152D0
公开(公告)日:2006-01-15
申请号:IL16615205
申请日:2005-01-05
Applicant: MAUNA KEA TECHNOLOGIES
Abstract: A method for processing an image acquired through a guide consisting of a plurality of optical fibers includes, for each optical fiber, isolating on the acquired image a zone corresponding to the optical fiber, locally processing each zone individually to correct the photon flux detected in each optical fiber, then reconstructing the acquired image by eliminating the pattern caused by the optical fiber. The method also includes a sampling process for obtaining, for each optical fiber and from a sampling image, a sample injection rate which can be used for reconstructing the acquired images. The method also includes a prior step which consists in detecting the fibers from a target.
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公开(公告)号:DK1468322T3
公开(公告)日:2005-12-05
申请号:DK02805803
申请日:2002-12-20
Applicant: MAUNA KEA TECHNOLOGIES
Inventor: PERCHANT AYMERIC , BERIER FREDERIC , LACOMBE FRANCOIS , BOURRIAUX STEPHANE , VIELLEROBE BERTRAND , GENET MAGALIE , LE GOUALHER GEORGES , MARTI SANDRA
Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.
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公开(公告)号:FR2868279A1
公开(公告)日:2005-10-07
申请号:FR0403519
申请日:2004-04-02
Applicant: MAUNA KEA TECHNOLOGIES SOC PAR
Inventor: LACOMBE FRANCOIS , LE GOUALHER GEORGES , PERCHANT AYMERIC , AYACHE NICHOLAS
IPC: A61B3/12 , G01F1/00 , G01F1/708 , G01N15/14 , G01S15/89 , G02B21/00 , A61B5/00 , G01P5/00 , G02B23/26 , G02B26/10
Abstract: L'invention concerne un procédé pour mesurer la vitesse d'une particule telle un globule rouge en mouvement au sein d'un écoulement, tel qu'un flux sanguin, à partir d'un microscope à balayage lumineux, ce procédé comprenant les étapes suivantes :- acquisition d'une image par balayage lumineux en x et y d'un plan contenant ledit objet;- détection dans le plan (x, y) d'une strie engendrée par le déplacement dudit objet lors de l'acquisition de ladite image;- détermination de la pente de ladite strie dans le plan (x, y);- estimation de la vitesse Vg dudit objet à partir de la pente ainsi déterminée.
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公开(公告)号:FR2865370A1
公开(公告)日:2005-07-29
申请号:FR0400582
申请日:2004-01-22
Applicant: CENTRE NAT RECH SCIENT , OBSERVATOIRE PARIS , MAUNA KEA TECHNOLOGIES
Inventor: LACOMBE FRANCOIS , LAFAILLE DAVID , GLANC MARIE , GENDRON ERIC
Abstract: The system has a deformable mirror placed between a Michelson interferometer and the eye, to compensate geometric aberrations of the eye. A focalization regulating unit regulates focalization of Shack-Hartmann analyzer, and forces the mirror to bend in order to conjugate an input light source and a detector with a predetermined depth point in retina. The unit is controlled in synchronism with scanning of tomography arrangement. An independent claim is also included for an in vivo tomography method for human retina.
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