公开(公告)号：EP2537053A4

公开(公告)日：2013-12-11

申请号：EP11745380

申请日：2011-02-18

Applicant: PACIFIC BIOSCIENCES CALIFORNIA ,  FEHR ADRIAN ,  MCCAFFREY NATHANIEL JOSEPH ,  TURNER STEPHEN

Inventor： FEHR ADRIAN ,  MCCAFFREY NATHANIEL JOSEPH ,  TURNER STEPHEN

IPC: G01N21/64 ,  B82Y20/00

CPC classification number: C12Q1/6874 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/168 ,  B82Y20/00 ,  C12Q1/6825 ,  C12Q1/6869 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/64 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6452 ,  G01N21/6454 ,  G01N21/6456 ,  G01N21/648 ,  G01N21/75 ,  G01N21/77 ,  G01N33/54373 ,  G01N2021/0346 ,  G01N2021/6434 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/6463 ,  G01N2021/757 ,  G01N2021/7786 ,  G01N2201/067 ,  G01N2201/068 ,  G01N2201/08 ,  G02B6/1226 ,  Y10T436/143333

Abstract: A system for measuring analytical reactions comprising a socket (51, 57) which is suitable for holding an optode array chip (40).The socket comprises electrical contacts that mate with electrical contacts on a chip when such a chip is inserted into the socket. The socket furthermore permits fluid from a fluidics system (33) and illumination from an illumination system (53) to be for delivered to a chip when such a chip is inserted into the socket. The socket may be of the clam shell type.

Abstract translation: 一种用于测量分析反应的系统，包括适于保持光栅阵列芯片（40）的插座（51,57）。当这种芯片插入插座时，该插座包括与芯片上的电触点相配合的电触点。 插座还允许来自流体系统（33）的流体和来自照明系统（53）的照明在将芯片插入插座时被输送到芯片。 插座可以是蛤壳型。

公开(公告)号：EP1984712A4

公开(公告)日：2013-02-20

申请号：EP07750629

申请日：2007-02-09

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： LUNDQUIST PAUL ,  ZACCARIN DENIS ,  LACROIX YVES ,  TURNER STEPHEN ,  DIXON JOHN

IPC: G01N21/64 ,  G01J3/02 ,  G01J3/28 ,  G01J3/30

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/10 ,  G01J3/14 ,  G01J3/2803 ,  G01N21/6445 ,  G01N21/6456 ,  G01N21/648 ,  G01N2021/6417 ,  G01N2021/6441

公开(公告)号：EP2274449A4

公开(公告)日：2012-04-18

申请号：EP09724672

申请日：2009-03-27

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： TRAVERS KEVIN ,  OTTO GEOFF ,  TURNER STEPHEN ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/68

CPC classification number: G06F19/22 ,  C12Q1/6806 ,  C12Q1/6855 ,  C12Q1/6869 ,  C12Q1/689 ,  C12Q2525/307 ,  C12Q2525/301 ,  C12Q2525/155 ,  C12Q2531/125 ,  C12Q2535/122

Abstract: Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

公开(公告)号：EP2274446A4

公开(公告)日：2011-04-20

申请号：EP09755191

申请日：2009-03-30

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： BJORNSON KEITH ,  LEE HAROLD ,  KORLACH JONAS ,  TURNER STEPHEN ,  BIBILLO AREK ,  CHRISTIANS FRED ,  EMIG ROBIN ,  HE MOLLY ,  PARK INSIL ,  JIA LEI ,  FEDOROV ANDREI ,  LYLE JOHN M

IPC: C12Q1/68 ,  C12N9/12 ,  C12Q1/48

CPC classification number: C12Q1/6869 ,  C12Q1/6874 ,  C12Q2527/125 ,  C12Q2527/119 ,  C12Q2527/101 ,  C12Q2565/1015 ,  C12Q2527/137 ,  C12Q2521/101

公开(公告)号：EP2002019A4

公开(公告)日：2009-07-15

申请号：EP07754529

申请日：2007-03-29

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： RANK DAVID R ,  WEGENER JEFFERY ,  KORLACH JONAS ,  ROITMAN DANIEL ,  XU YUE ,  LYLE JOHN ,  TURNER STEPHEN ,  PELUSO PAUL ,  OTTO GEOFF

IPC: C12N11/00 ,  C40B40/04

CPC classification number: C12Q1/6874 ,  B01J19/0046 ,  B01J2219/00427 ,  B01J2219/0045 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00626 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00639 ,  B01J2219/00659 ,  B01J2219/00711 ,  B01J2219/00722 ,  B82Y20/00 ,  B82Y30/00 ,  C12Q1/6837 ,  Y10T29/49002 ,  C12Q2565/629 ,  C12Q2527/127

Abstract: Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.

公开(公告)号：EP1963501A4

公开(公告)日：2009-04-22

申请号：EP06848977

申请日：2006-12-21

Applicant: PACIFIC BIOSCIENCES CALIFORNIA

Inventor： HANZEL DAVID ,  KORLACH JONAS ,  PELUSO PAUL ,  OTTO GEOFF ,  PHAM THANG ,  RANK DAVID ,  TURNER STEPHEN

IPC: C12N11/00 ,  C12N11/16 ,  G01N33/53

CPC classification number: C12N9/22 ,  C07K2319/21 ,  Y10T428/2991 ,  Y10T428/2993 ,  Y10T428/2996 ,  Y10T428/31663 ,  Y10T428/31768

Abstract: Isolated and/or recombinant enzymes that include surface binding domains, surfaces with active enzymes bound to them and methods of coupling enzymes to surfaces are provided. Enzymes can include large and/or multiple surface coupling domains for surface coupling.