公开(公告)号：AT173395T

公开(公告)日：1998-12-15

申请号：AT94924232

申请日：1994-07-05

Applicant: BASF AG

Inventor： SCHADE CHRISTIAN ,  WESTENFELDER HORST ,  SPERLING-VIETMEIER KARIN ,  SANNER AXEL ,  WEKEL HANS-ULRICH

IPC: A61K47/30 ,  A61K8/06 ,  A61K8/72 ,  A61K8/81 ,  A61K9/113 ,  A61K47/32 ,  C08F2/08 ,  C08F20/04 ,  C08F20/06 ,  C08F220/00 ,  C08F220/06 ,  C08F220/08 ,  C08F222/00 ,  C08K3/20 ,  C09K23/00 ,  C09K23/52 ,  A61K7/48

Abstract: The use of crosslinked copolymers obtainable by precipitation polymerization of monomer mixtures comprising(a) monoethylenically unsaturated C3-C8-carboxylic acids, their anhydrides or mixtures of said carboxylic acids and anhydrides,(b) compounds with at least 2 non-conjugated ethylenic double bonds in the molecule as crosslinkers and, where appropriate,(c) other monoethylenically unsaturated monomers which are copolymerizable with monomers (a) and (b),in the presence of free-radical polymerization initiators and from 0.1 to 20% by weight, based on the monomers used, of saturated, nonionic surface-active compounds, as stabilizer in oil-in-water emulsions in amounts of from 0.01 to 5% of the weight of the emulsions, and cosmetic and pharmaceutical formulations based on oil-in-water emulsions which contain said precipitation polymers.

公开(公告)号：MX9800488A

公开(公告)日：1998-10-31

申请号：MX9800488

申请日：1998-01-15

Applicant: BASF AG

Inventor： DROEGEMUELLER MICHAEL ,  BOMM VOLKER ,  SCHELMANN VOLKER ,  WESTENFELDER HORST

IPC: A61K8/00 ,  A61Q17/04 ,  C07C225/14 ,  C07D215/42 ,  C07C229/54 ,  C07C237/30 ,  C07C309/46 ,  C07C311/39 ,  C09K3/00 ,  A61K07/42 ,  C07C49/413

Abstract: Los derivados arilaminometilencanfor de la formula (I): en donde el doble enlace C=C se encuentra en la configuracion Z o E, y las variables tienen los siguientes significados: R1 H, CH3, R2 H, alquilo de C1-C6, cicloalquilo de C3-C8, alquenilo de C2-C6, cicloalquenilo de C3-C8, arilo o arilo sustituido, R3 H, alquilo de C1-C6, cicloalquilo de C3-C8, arilo, arilo sustituido, alcoxi de C1-C6, acilo de C1-C8, Ar arilo, arilo sustituido, hetarilo o hetarilo sustituido, se utilizan como agentes bloqueadores de los rayos solares, especialmente en formulaciones cosméticas y farmacéuticas.

公开(公告)号：DE19701448A1

公开(公告)日：1998-07-23

申请号：DE19701448

申请日：1997-01-17

Applicant: BASF AG

Inventor： DROEGEMUELLER MICHAEL DR ,  BOMM VOLKER DR ,  SCHEHLMANN VOLKER DR ,  WESTENFELDER HORST

IPC: C07D215/42 ,  A61K8/00 ,  A61Q17/04 ,  C07C225/14 ,  C07C229/54 ,  C07C237/30 ,  C07C309/46 ,  C07C311/39 ,  C09K3/00 ,  C07C229/56 ,  C07C229/60 ,  C09K15/20 ,  C09K15/22 ,  A61K7/42 ,  A61K7/44

Abstract: Arylaminomethylene-camphor derivatives of formula (I) are new: R1 = H or Me; R2 = H, 1-6C alkyl, 3-8C cycloalkyl, 2-6C alkenyl; 3-8C cycloalkenyl or aryl (optionally substituted); R3 = H, 1-6C alkyl, 3-8C cycloalkyl, aryl (optionally substituted), 1-6C alkoxy or 1-8C acyl; and Ar = aryl or heteroaryl (both optionally substituted); NB the double bond is Z or E configuration.

公开(公告)号：DE19649381A1

公开(公告)日：1998-06-04

申请号：DE19649381

申请日：1996-11-29

Applicant: BASF AG

Inventor： HABECK THORSTEN DR ,  AUMUELLER ALEXANDER DR ,  SCHEHLMANN VOLKER DR ,  WESTENFELDER HORST ,  WUENSCH THOMAS DR

IPC: A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61K8/49 ,  A61Q1/04 ,  A61Q17/04 ,  C07C229/56 ,  C07C229/60 ,  C07C255/30 ,  C07C255/58 ,  C07C309/46 ,  C07D275/02 ,  C07D275/03 ,  C07D319/06 ,  C07D333/38 ,  A61K7/06 ,  A61K7/42

Abstract: The use of UV filter compounds of formula (I) is claimed in cosmetic products to protect human skin or hair against sunlight, where (I) are used alone or in combination with other UV filters. R1-R3 = H, 1-18C aliphatic or up to 18C cycloaliphatic group; or CR1R2 = a 5-6 membered ring; R4 = H, aliphatic, cycloaliphatic, arylaliphatic or aromatic group containing up to 18C; and R5 = optionally substituted 5-12 membered aromatic or heteroaromatic ring. Also claimed are cosmetic products containing UV filters, including effective amounts of (I), in a suitable carrier to protect the skin or hair against UV light at 280-400 nm. (I) are new when R1-R3 = Me; R4 = H; and R5 = phenyl (optionally substituted by 1-20C alkyl, 1-20C alkoxy, 1-20C alkylaminocarbonyl, 1-20C alkoxycarbonyl, CN, COOH, carboxylate, sulphonate or alkylammonium).

公开(公告)号：MX9709075A

公开(公告)日：1998-05-31

申请号：MX9709075

申请日：1997-11-25

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  AUMULLER ALEXANDER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUNSCH THOMAS

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/41 ,  A61K8/42 ,  A61K8/46 ,  A61K8/49 ,  A61K31/13 ,  A61K31/22 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  A61Q19/00 ,  C07C225/14 ,  C07C229/30 ,  C07C229/56 ,  C07C229/60 ,  C07C255/30 ,  C07C255/58 ,  C07C309/46 ,  C07D275/02 ,  C07D275/03 ,  C07D319/06 ,  C07D333/38 ,  A61K07/42

Abstract: El empleo de compuestos de la formula I: donde el doble enlace C=C se encuentra en la configuracion E o bien Z, las variables tienen los siguientes significados: R1 representa COOR5, COR5, CONR5R6, CN, O=S(-R5)=O, O=S(-OR5)=O, R7O-P(-OR8)=O; R2 representa COOR6, COR6, CONR5R6, CN, O=S(-R6)=O, O=S(-OR6)=O, R7O-P(-OR8)=O; Re representa hidrogeno, un radical alifático; cicloalifático, aralifático o bien aromático eventualmente sustituido con gasta 18 átomos de carbono; R4 representa un radical aromático o bien heteroaromático eventualmente sustituido con 5 a 12 átomos de anillo; R5 bis R8 representa independientemente entre ellos hidrogeno, un radical cicloalifático, aralifático, alifático de cadena abierta o bien ramificado o bien un radical aromático eventualmente sustituido con hasta 18átomos de carbono, donde las variables R3 hasta R8 entre ellas, cada vez juntas con los átomos de carbono en donde están unidas, pueden formar juntos un anillo de 5 o 6 átomos que eventualmente puede tener anillos adicionales, como filtros contra radiaciones UV en preparaciones cosméticas y farmacéuticas para la proteccion de la piel humana o bien del pelo humano contra radiaciones solares, solos o bien juntos con preparaciones farmacéuticas y cosméticas conocidas, en compuestos que absorben los rayos dentro del rango de las radiaciones UV.

公开(公告)号：DE19643515A1

公开(公告)日：1998-04-23

申请号：DE19643515

申请日：1996-10-22

Applicant: BASF AG

Inventor： SPERLING KARIN DR ,  WUENSCH THOMAS DR ,  WESTENFELDER HORST ,  TRENTMANN BEATE DR

IPC: C07D251/34 ,  A61K8/00 ,  A61K8/33 ,  A61K8/37 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q5/00 ,  A61Q17/04 ,  A61K7/44

公开(公告)号：IT1283144B1

公开(公告)日：1998-04-07

申请号：ITMI961443

申请日：1996-07-12

Applicant: BASF AG

Inventor： KANDZIA CHRISTOF ,  WESTENFELDER HORST

IPC: C09K3/00 ,  A61K8/37 ,  A61K8/67 ,  A61Q17/04 ,  C09K15/08

公开(公告)号：DE19634401A1

公开(公告)日：1998-03-05

申请号：DE19634401

申请日：1996-08-26

Applicant: BASF AG

Inventor： KELLER HARALD DR ,  SPERLING KARIN DR ,  WESTENFELDER HORST

IPC: A61K8/00 ,  A61K8/04 ,  A61K8/81 ,  A61Q17/04 ,  A61K7/42

公开(公告)号：AU3519397A

公开(公告)日：1998-02-26

申请号：AU3519397

申请日：1997-08-21

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  AUMUELLER ALEXANDER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUENSCH THOMAS

IPC: A61K8/00 ,  A61K8/30 ,  A61K8/40 ,  A61K8/49 ,  A61K8/92 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C255/40 ,  C07D307/52 ,  C07D317/54 ,  C07D333/24 ,  A61K7/42 ,  C07D333/22

Abstract: The use of compounds of formula (I) as UV-A filters in cosmetic products (optionally in combination with standard UV absorbers) to protect the human skin against sunlight is claimed. R1-R3 = H or (cyclo)aliphatic group containing up to 18 C, or two of these groups can combine to form a 5 or 6-membered ring ; R4 = optionally substituted (hetero)aryl containing 5-12 ring atoms ; and R5 = R4 or H. Also claimed are (i) cosmetic products containing (I) for protecting the epidermis layer against UV radiation with a wavelength of 280-400 nm and (ii) compounds of formula (II) : R7-R9 = lower alkyl ; R6 = 2-thienyl (optionally substituted with lower alkyl), 4-(3,5-di-t-butyl)-1-hydroxyphenyl or 4-(3,5-di-t-butyl)-1-alkoxyphenyl.

公开(公告)号：ES2103473T3

公开(公告)日：1997-09-16

申请号：ES93911463

申请日：1993-04-14

Applicant: BASF AG

Inventor： SCHADE CHRISTIAN ,  SANNER AXEL ,  WEKEL HANS-ULRICH ,  FROSCH FRANZ ,  WESTENFELDER HORST

IPC: A61K8/06 ,  A61K8/72 ,  A61K47/30 ,  A61K8/81 ,  A61K9/10 ,  A61K47/32 ,  A61Q19/00 ,  C08F20/02 ,  C08F20/10 ,  C08F20/26 ,  C08F220/02 ,  C08F220/04 ,  C08F220/06 ,  C08F220/20 ,  C08F220/28 ,  C08F222/00 ,  C08F222/02 ,  C08F222/04 ,  C08L33/02 ,  C09K23/52 ,  A61K7/48

Abstract: The use of copolymers obtainable by the radically initiated polymerization of A) 50 to 99.9 wt % of an olefinically unsaturated C3 to C5 monocarboxylic acid, an olefinically unsaturated C4 to C8 dicarboxylic acid or its anhydride, or a mixture of such carboxylic acids or carboxylic acid anhydrides with B) 0.1 to 50 wt % of one or more long-chained compounds with isolated multiple C-C bonds from the group (1) mono or polyunsaturated C8 to C30 monocarboxylic acids which may have additional hydroxyl groups and their alkaline metal and earth alkaline metal salts, alkyl esters, amides, sorbitane esters, glycerin esters and polyglycerin esters, (2) mono or polyunsaturated aliphatic Ca to C30 amines, (3) mono or polyunsaturated C8 to C30 alcohols and esters thereof with saturated Cl to C4 monocarboxylic acids, (4) to (C8 to C30 alkyl) vinyl ether which may incorporate up to 25 alkylene oxide units, and (5) final and medium-position Ci3 to C30 alkenes; C) 0 to 49.9 wt % of other copolymerizable monomers, and D) 0 to 10 wt % of one or more compounds with at least two olefinically unsaturated groups in the molecule as cross-linking agents, as thickening or dispersing agents, especially in cosmetic and pharmaceutical preparations.