公开(公告)号：DE3171074D1

公开(公告)日：1985-07-25

申请号：DE3171074

申请日：1981-12-23

Applicant: BASF AG

Inventor： THIEME PETER C DR ,  STEINER GERD DR ,  ROHR WOLFGANG DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  WEIFENBACH HARALD DR ,  TESCHENDORF HANS-JUERGEN DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/495 ,  A61K31/496 ,  A61P9/02 ,  A61P11/00 ,  A61P25/20 ,  C07D231/12 ,  C07D233/60 ,  C07D233/61 ,  C07D271/10 ,  C07D295/06 ,  C07D295/067 ,  C07D295/096 ,  C07D521/00

Abstract: Novel phenylpiperazinylpropane and -butane derivatives of hetarylphenols and hetarylanilines of the formula where R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, X is oxygen or an NH group, and the heterocyclic structure Het. is 1,3,4-oxadiazolyl, triazolyl, imidazolyl or pyrazolyl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly sedative, neuroleptic and hypotensive properties.

公开(公告)号：DE3309719A1

公开(公告)日：1984-09-20

申请号：DE3309719

申请日：1983-03-18

Applicant: BASF AG

Inventor： STEINER GERD DR

IPC: C07C45/00 ,  C07C46/06 ,  C07C50/24 ,  C07C67/00 ,  C07C325/00 ,  C07C327/20 ,  C07C327/26 ,  C07D333/72 ,  C07D495/04 ,  C07C153/07

公开(公告)号：DE3212794A1

公开(公告)日：1983-10-13

申请号：DE3212794

申请日：1982-04-06

Applicant: BASF AG

Inventor： STEINER GERD DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER PROF DR

IPC: A61K31/55 ,  A61P1/04 ,  C07D223/20 ,  C07D403/12

Abstract: 5,6-Dihydro-11-methylenemorphanthridin-6-ones of the formula I I where R1, R2, R3 and R4 have the meanings given in the description, and their preparation and use. The novel substances are particularly useful for treating gastric and duodenal ulcers.

公开(公告)号：DE3064096D1

公开(公告)日：1983-08-18

申请号：DE3064096

申请日：1980-05-05

Applicant: BASF AG

Inventor： STEINER GERD DR ,  FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  TESCHENDORF HANS-JUERGEN DR ,  WORSTMANN WOLFGANG DR ,  KREISKOTT HORST DR

IPC: A61K31/55 ,  A61P25/18 ,  C07D223/20 ,  C07D401/06 ,  C07D403/04

Abstract: 6-Substituted 11-alkylene-morphanthridines, also referred to as 11-alkylene-dibenzo[b,e]-azepines, their pure cis- and trans-isomers, processes for their preparation, and therapeutic agents containing these compounds, which may be used as drugs, in particular neuroleptics, sedatives, hypnotics, analgesics, antidepressants or agents for treating Parkinson's syndrome.

公开(公告)号：DE19724980A1

公开(公告)日：1998-12-17

申请号：DE19724980

申请日：1997-06-13

Applicant: BASF AG

Inventor： STEINER GERD DR ,  DULLWEBER UTA DR ,  STARCK DOROTHEA DR ,  BACH ALFRED DR ,  WICKE KARSTEN DR ,  TESCHENDORF HANS-JUERGEN DR ,  GARCIA-LADONA FRANCISCO-JAVI D ,  EMLING FRANZ DR

IPC: A61K31/495 ,  A61K31/519 ,  A61P25/00 ,  A61P25/24 ,  A61P43/00 ,  C07D495/04 ,  A61K31/505 ,  A61K31/55

Abstract: The invention relates to 3-substituted 3,4 dihydro-thieno[2, 3-d] pyrimidine derivatives of formula (I) wherein R and R mean a hydrogen atom or a C1-C4 alkyl group, R represents a phenyl, pyridyl, pyrimidinyl or pyrazinyl group optionally mono- or disubstituted by halogen atoms, C1-C4 alkyl, trifluoromethyl, trifluoromethoxy, hydroxy, C1-C4 alkoxy, amino, monomethylamino, dimethylamino, cyano or nitro groups, said group being optionally anellated with a benzene nucleus which is optionally mono- or disubstituted by halogen atoms, C1-C4 alkyl, hydroxy, trifluoromethyl, C1-C4 alkoxy, amino, cyano or nitro groups and may contain optionally 1 nitrogen atom, or with a 5 or 6-membered ring which may contain 1-2 oxygen atoms, A represents NH or an oxygen atom, Y is CH2, CH2-CH2, CH2-CH2-CH2 or CH2-CH, Z represents a nitrogen atom, carbon atom or CH and the bond between Y and Z can also be a double bond, and n is the number 2, 3 or 4. The invention also relates to the physiologically compatible salts of the inventive 3-substituted 3,4 dihydro-thieno[2,3-d] pyrimidine derivatives.

公开(公告)号：DE59108419D1

公开(公告)日：1997-01-30

申请号：DE59108419

申请日：1991-07-10

Applicant: BASF AG

Inventor： MUENSTER PETER DR ,  FREUND WOLFGANG DR ,  STEINER GERD DR ,  WALTER HELMUT DR ,  WESTPHALEN KARL-OTTO DR ,  GERBER MATTHIAS DR

IPC: A01N43/36 ,  A01N43/90 ,  C07D307/68 ,  C07D333/38 ,  C07D333/40 ,  C07D409/04 ,  C07D409/12 ,  C07D491/04 ,  C07D491/048 ,  C07D495/04

Abstract: Dicarboximides of the general formula Ia and Ib ulfur, R1 is hydrogen, cycloalkyl, alkyl, hydroxyl, alkoxy, cyanoalkyl, alkenyl, alkynyl, phenyl, naphthyl or a 5-membered or 6-membered heterocyclic structure, where the stated radicals may be substituted, and R2 and R3 are each nitro, cyano, halogen, amino, mono- or dialkylamino, alkylcarbonylamino, unsubstituted or halogen-substituted alkoxy or alkylthio, alkylsulfonyl, haloalkylsulfonyl, alkenyl, alkynyl, phenyl, phenoxy or phenylthio or one of the radicals R1, with the proviso that specific compounds named in the description are excluded. Processes for the preparation of the compounds Ia and Ib and herbicides containing them.

公开(公告)号：CZ278593A3

公开(公告)日：1995-07-12

申请号：CZ278593

申请日：1993-12-16

Applicant: BASF AG

Inventor： STEINER GERD DR ,  UNGER LILIANE DR ,  BEHL BERTHOLD DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D209/02 ,  A61K31/40

公开(公告)号：DE4341402A1

公开(公告)日：1995-06-08

申请号：DE4341402

申请日：1993-12-04

Applicant: BASF AG

Inventor： STEINER GERD DR ,  MUNSCHAUER RAINER DR ,  UNGER LILIANE DR ,  TESCHENDORF HANS-JUERGEN DR ME ,  HOEGER THOMAS DR

IPC: C07D401/04 ,  A61K31/40 ,  A61K31/403 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/443 ,  A61K31/4433 ,  A61K31/505 ,  A61P25/00 ,  A61P25/02 ,  A61P25/08 ,  A61P25/18 ,  A61P25/28 ,  A61P43/00 ,  C07D209/02 ,  C07D209/46 ,  C07D209/52 ,  C07D209/90 ,  C07D209/96 ,  C07D403/04 ,  C07D403/06 ,  C07D405/06 ,  C07D409/04 ,  C07D409/06 ,  C07D413/06 ,  C07D417/04 ,  C07D417/14 ,  C07B37/10

Abstract: PCT No. PCT/EP94/03910 Sec. 371 Date Apr. 19, 1996 Sec. 102(e) Date Apr. 19, 1996 PCT Filed Nov. 26, 1994 PCT Pub. No. WO95/15312 PCT Pub. Date Jun. 8, 1995Compounds of the formula I I where the substituents have the meanings given in the description, and their preparation are described. The novel compounds are suitable for the control of diseases.

公开(公告)号：DE4219975A1

公开(公告)日：1993-12-23

申请号：DE4219975

申请日：1992-06-19

Applicant: BASF AG

Inventor： STEINER GERD DR

IPC: C07D209/52 ,  C07D401/04 ,  C07D403/04 ,  C07D409/04

Abstract: New 3-azabicyclo[3.2.0]heptane derivates having the formula (I), in which R and R have the meaning given in the description, are disclosed, as well as their preparation. These substances constitute intermediate products for the preparation of medicaments.

公开(公告)号：DE3882589D1

公开(公告)日：1993-09-02

申请号：DE3882589

申请日：1988-05-13

Applicant: BASF AG

Inventor： STEINER GERD DR ,  PFISTER JUERGEN DR ,  TESCHENDORF HANS-JUERGEN DR ,  UNGER LILIANE DR ,  BINDER RUDOLF DR

IPC: A61K31/55 ,  A61P21/02 ,  A61P25/00 ,  A61P25/02 ,  A61P25/20 ,  C07D487/04

Abstract: 4-Amino-10-cyanomethylene -pyrrolo (3,4-c) benz(b)azepine derivs. of formula (I) and their acid-addn. salts are new: In (I), R1 = H, halogen, 1-3C alkyl, CF3 or 1-3C alkoxy; R2 and R3 = H or halogen; R4 = H, 1-3C alkyl, or aryl (1-3C) alkyl opt. ring-substd. by halogen, 1-3C alkyl or OMe; A = NR3R6 or NHR7; NR5R6 is a satd. 5- to 7-membered ring opt. contg. O, NR or NR-O; R = H, 1-3C alkyl, 2-3C hydroxyalkyl, 2-3C alkoxyalkyl, 3-7C cycloalkyl, (3-7C cycloalkyl)methyl or 2-5C alkynyl; R7 = 2-7C aminoalkyl in which the amine N is opt. substd. by a 1-5C alkyl gp. or forms part of a satd. 5- to 7-membered ring opt. contg. O or NR"; R" = H, 1-3C alkyl or 2-3C hydroxyalkyl. 10-Cyanomethylene-4- (4-methyl-1-piperazinyl)- pyrrolo (3,4-c) benz(b)azepine and its 7-chloro deriv. are specifically claimed.