Patent search ap:("VERTEX PHARMA") AND inv:"DINEHART KIRK" Page 2

11.

发明专利
FARMACEUTSKI PRIPRAVAK N-[2,4-bis(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDRO-4-OKSOKINOLIN-3-KARBOKSAMIDA I NJEGOVO DAVANJE 未知

公开(公告)号：HRP20180328T1

公开(公告)日：2018-04-20

申请号：HRP20180328

申请日：2018-02-22

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO

IPC: A61K47/32 , A61K9/16 , A61K9/20 , A61K9/28 , A61K31/47

12.

发明专利
PHARMACEUTICAL COMPOSITION COMPRISING A SOLID DISPERSION OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：CA2733908C

公开(公告)日：2017-05-30

申请号：CA2733908

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO

IPC: A61K47/32

Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N- [2,4-Bis( 1, 1-dimethylethyl)-5 -hydroxyphenyl]- 1,4-dihydro-4-oxoquinoline-3-carboxamide, and a polymer, wherein Compound 1 is present in an amount of about 80% by weight of the solid dispersion.

13.

发明专利
Pharmaceutcial composition comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide 未知

公开(公告)号：NZ591535A

公开(公告)日：2012-12-21

申请号：NZ59153509

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D

IPC: A61K47/32 , A61K9/42 , A61K31/47

Abstract: Disclosed is a pharmaceutical composition comprising: a solid dispersion of substantially amorphous N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), hydroxypropylmethylcellulose acetate succinate and sodium lauryl sulfate, microcrystalline cellulose, lactose, sodium croscarmellose, SLS, colloidal silicon dioxide, magnesium stearate.

14.

发明专利
未知

公开(公告)号：BRPI0511900A

公开(公告)日：2008-01-22

申请号：BRPI0511900

申请日：2005-06-08

Applicant: VERTEX PHARMA

Inventor： MURPHY MAURA , DINEHART KIRK , HURTER PATRICIA , CONNELLY PATRICK , CUI YONG

IPC: A61K9/00 , A01N43/40 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/454 , A61K45/06

Abstract: Forms and formulations of VX-950 and uses thereof.

15.

发明专利
Pharmaceutical compositions 未知

公开(公告)号：AU2005253957A1

公开(公告)日：2005-12-29

申请号：AU2005253957

申请日：2005-06-08

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CUI YONG , DINEHART KIRK , CONNELLY PATRICK , MURPHY MAURA

IPC: A61K9/00 , A01N43/40 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/454 , A61K45/06

Abstract: Forms and formulations of VX-950 and uses thereof.

16.

发明专利
未知

公开(公告)号：ES2718273T5

公开(公告)日：2025-02-06

申请号：ES10708442

申请日：2010-02-18

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS , OVERHOFF KIRK , GROOTENHUIS PETER , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F

IPC: A61K9/14 , A61K31/44 , A61K31/47 , A61K45/06 , A61P19/00 , A61P19/10 , A61P43/00

17.

发明专利
FORMULACIJA N-[2,4-BIS(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDR0-4-OKSOHINOLIN-3-KARBOKSAMIDA U OBLIKU TABLETE ZA UPOTREBU U TRETMANU CISTIĆNE FIBROZE 未知

公开(公告)号：ME03356B

公开(公告)日：2019-10-20

申请号：MEP10119

申请日：2010-02-18

Applicant: VERTEX PHARMA

Inventor： VAN GOOR FREDRICK F , ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER R , DINEHART KIRK , VERWIJS MARINUS JACOBUS , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , OVERHOFF KIRK , GROOTENHUIS PETER D J

IPC: A61K31/44 , A61K9/14 , A61K31/47 , A61K45/06 , A61P19/00 , A61P19/10 , A61P43/00

18.

发明专利
N-[2,4-BIS(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDRO-4-OKSOCHINOLIN-3-KARBOKSAMIDO TABLETĖS FORMA, SKIRTA PANAUDOTI CISTINĖS FIBROZĖS GYDYMUI 未知

公开(公告)号：LT2464337T

公开(公告)日：2019-05-10

申请号：LT10708442

申请日：2010-02-18

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS , OVERHOFF KIRK , GROOTENHUIS PETER , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F

IPC: A61K9/14 , A61K31/44 , A61K31/47 , A61K45/06 , A61P19/00 , A61P19/10 , A61P43/00

19.

发明专利
N-[2,4-BIS(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDRO-4- OKSOCHINOLIN-3-KARBOKSAMIDO FARMACINĖS KOMPOZICIJOS IR JŲ ĮVEDIMAS 未知

公开(公告)号：LT2328618T

公开(公告)日：2018-03-26

申请号：LT09789125

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO

IPC: A61K47/32 , A61K9/16 , A61K9/20 , A61K9/28 , A61K31/47

20.

发明专利
ТАБЛЕТКА, СОДЕРЖАЩАЯ ТВЕРДУЮ ДИСПЕРСИЮ N-[2,4-БИС-(1,1-ДИМЕТИЛЭТИЛ)-5-ГИДРОКСИФЕНИЛ]-1,4-ДИГИДРО-4-ОКСОХИНОЛИН-3-КАРБОКСАМИДА, И ЕЕ ВВЕДЕНИЕ 未知

公开(公告)号：EA021706B1

公开(公告)日：2015-08-31

申请号：EA201170330

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO

IPC: A61K47/32

Abstract: Изобретениеотноситсяк областифармацевтики, аименнок таблетке, содержащейтвердуюдисперсию N-[2,4-бис-(1,1-диметилэтил)-5-гидроксифенил]-1,4-дигидро-4-оксохинолин-3-карбоксамидаи способуеевведения. Заявленнаятаблеткахарактеризуетсяхорошейрастворимостьюи высокойстабильностью.

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