公开(公告)号：CA2163255A1

公开(公告)日：1994-11-24

申请号：CA2163255

申请日：1994-05-09

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  MUELLER WINFRIED ,  ROSENBERG JOERG ,  BINDER RUDOLF ,  SANNER AXEL

IPC: A61K47/32 ,  A61K9/14 ,  A61K31/37 ,  A61K31/41 ,  A61K31/425 ,  A61K31/433 ,  A61K47/30 ,  A61K47/38

Abstract: Compositions in the form of solid solutions contain (a) 1 to 90 % by weight of a coumarin derivate A from the group of the heterocyclic substituted alkoxycoumarins or of the sulfonic acid-esterified hydroxycoumarins as active substance and (b) 10 to 99 % by weight of at least a water-soluble polymer B as excipient.

公开(公告)号：CA2230950C

公开(公告)日：2007-12-04

申请号：CA2230950

申请日：1996-09-30

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  ROSENBERG JOERG ,  ZEIDLER JURGEN ,  NEUMANN JORG

IPC: A61K9/20 ,  A61J3/06 ,  A61K9/16 ,  A61K31/275 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30 ,  A61K47/34 ,  A61K47/38

Abstract: The invention concerns solid medicaments obtained by extrusion with subseque nt shaping of a solvent-free melt, containing in addition to one or a plurality of active substances: A) between 10 and 90 wt.% of a thermoplastically processable water-soluble polymer, B) between and 85 wt.% isomalt; and C) between 0 and 5 wt.% lecithin, the total of all the contents equalling 100 wt.%.

公开(公告)号：ES2199373T3

公开(公告)日：2004-02-16

申请号：ES97942022

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：DE59809891D1

公开(公告)日：2003-11-20

申请号：DE59809891

申请日：1998-03-12

Applicant: BASF AG

Inventor： ZEIDLER JUERGEN ,  ROSENBERG JOERG ,  BREITENBACH JOERG ,  KLEINKE ANDREAS ,  MAIER WERNER

IPC: A61J3/10 ,  A61K9/20 ,  A61K47/26 ,  A61K47/30 ,  B30B11/16

公开(公告)号：DK0930875T3

公开(公告)日：2003-09-01

申请号：DK97942022

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：AT241425T

公开(公告)日：2003-06-15

申请号：AT98962431

申请日：1998-12-09

Applicant: BASF AG

Inventor： KLEINKE ANDREAS ,  FARWERCK KARL-PETER ,  JOCHUM ALFONS ,  LANGE ARMIN ,  KRULL HARALD ,  ROSENBERG JOERG ,  MAIER WERNER ,  JOTTER KARL LUDWIG ,  TRAPP BURKHARD ,  BREITENBACH JOERG

IPC: A61K9/16 ,  B01J2/20 ,  B29B9/06 ,  B30B9/28 ,  B30B11/22 ,  C05G3/00

公开(公告)号：HU221981B1

公开(公告)日：2003-03-28

申请号：HU9602878

申请日：1995-04-05

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/16 ,  A61K9/22

Abstract: Slow-release matrix pellets with a spherical or lenticular shape and uniform maximum diameters in the range from 0.5 to 4 mm, composed ofa) 0.1-87% by weight of at least one biologically active compound,b) 5-50% by weight of at least one water-insoluble polymer,c) 5-45% by weight of at least one lipophilic component as plasticizer for polymer b),d) 3-40% by weight of a natural or semisynthetic gel former,e) 0-50% by weight of one or more conventional formulation aids.

公开(公告)号：NO20025759L

公开(公告)日：2003-01-14

申请号：NO20025759

申请日：2002-11-29

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  HERR DIETER ,  LAUX VOLKER ,  HEGER ROBERT

IPC: A61K47/12 ,  A61K9/16 ,  A61K31/726 ,  A61K31/727 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K47/44 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  A61P37/06

公开(公告)号：AT228355T

公开(公告)日：2002-12-15

申请号：AT96934494

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JUERGEN ,  ROSENBERG JOERG ,  NEUMANN JOERG ,  BREITENBACH JOERG

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients,A) 10-90% by weight of a melt-processable, water-soluble polymer,B) 5-85% by weight of isomalt, andC) 0-5% by weight of lecithin,where the total of all the ingredients is to be equal to 100% by weight.

公开(公告)号：NO20025759D0

公开(公告)日：2002-11-29

申请号：NO20025759

申请日：2002-11-29

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  HERR DIETER ,  LAUX VOLKER ,  HEGER ROBERT

IPC: A61K47/12 ,  A61K9/16 ,  A61K31/726 ,  A61K31/727 ,  A61K47/14 ,  A61K47/30 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K47/44 ,  A61P1/04 ,  A61P7/02 ,  A61P9/00 ,  A61P9/06 ,  A61P9/10 ,  A61P11/00 ,  A61P13/12 ,  A61P19/02 ,  A61P27/02 ,  A61P29/00 ,  A61P35/00 ,  A61P35/04 ,  A61P37/06 ,  A61K