公开(公告)号：KR1020100006605A

公开(公告)日：2010-01-21

申请号：KR1020080066789

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  권세은 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P25/06 ,  A61P25/00

Abstract: PURPOSE: A composition containing dried powder of sand lance fraction or its extract is provided to suppress pain using an animal model by inducing acetic acid pain test, heat plate and tail flick test. CONSTITUTION: A pharmaceutical composition for preventing and treating pain contains dried powder or its extract of sand lance fraction as an active ingredient. The extract of sand lance fraction is obtained by heating the sand lance fraction at 60°C-150°C for 12 to 48 hours. The pain is the headache, toothache, backache, burn ache, neuralgia, period pains or arthralgia. The pharmaceutical composition contains 0.1-50 weight% of the dried powder or its extract based on the total weight.

Abstract translation: 目的：提供一种含有喷沙部分或其提取物的干粉的组合物，通过诱导乙酸疼痛试验，加热板和尾巴轻弹试验，通过动物模型抑制疼痛。 构成：用于预防和治疗疼痛的药物组合物含有干燥粉末或其作为活性成分的沙枪部分提取物。 通过在60℃-150℃下加热沙枪级分12至48小时获得沙枪分数的提取物。 疼痛是头痛，牙痛，背痛，疼痛，神经痛，周期痛或关节痛。 该药物组合物含有0.1-50重量％的干燥粉末或其提取物，基于总重量。

公开(公告)号：KR1020100006599A

公开(公告)日：2010-01-21

申请号：KR1020080066783

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  남정숙 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing dried powder and extract of chub mackerel fraction is provided to reduce total cholesterol and blood triglyceride content. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of dried powder or extract of chub mackerel fraction as an active ingredient. The fraction of the chub mackerel is head, cartilage, shell, muscle, eye, gill, total body of the fish. A method for preparing the dried powder of chub mackerel fraction comprises: a step of washing and removing foreign material and salt from the chub mackerel; and a step of cutting head, cartilage, shell, muscle, eye, gill, and total body. The extract is isolated using water, alcohol and spirit extract solvent.

Abstract translation: 目的：提供含有干粉的组合物和鲭鱼and提取物，以降低总胆固醇和血甘油三酯含量。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的干燥粉末或作为活性成分的鲭鱼片提取物。 小鲭鱼的分数是头，软骨，壳，肌肉，眼睛，鳃，鱼的全身。 一种制备鲭鱼m the干燥粉末的方法，包括：从鲭鱼鲭鱼中洗涤除去异物和盐的步骤; 并切割头，软骨，壳，肌肉，眼睛，鳃和全身的一个步骤。 使用水，酒精和精油提取物溶剂分离提取物。

公开(公告)号：KR1020090105984A

公开(公告)日：2009-10-08

申请号：KR1020080031422

申请日：2008-04-04

Applicant: 강릉원주대학교산학협력단

Inventor： 어명희 ,  김옥선 ,  김광우 ,  김정식 ,  박신호 ,  조순영

IPC: A61K8/65 ,  A61K8/98 ,  A61K35/60

Abstract: PURPOSE: A method for manufacturing collagen isolated from the skin of bigeye tuna is provided to produce high quality of collagen with high solubility and emulsion stability. CONSTITUTION: A method for manufacturing collagen isolated from the skin of bigeye tuna comprises: a step for washing the skin of the bigeye tuna which is stored at -30 °C to -100 °C; a step for treating the skin with 0.05 ~ 10.0 %(w/v) of alkali solution; a step for washing and neutralizing with distilled water; a step for adding 0.05 ~ 10.0 N of acid to the skin, then stirring and extracting; a step for separating extracted liquid and residue using a centrifuge; and a step for drying to obtain acid soluble collagen (AC); a step for adding 0.5 ~ 5.0 N of acid; a step for adding 0.5 ~ 10% of pepsin and stirring and hydrolyzing for 1 to 60 hours; a step for separating extract liquid and residue using a filter; a step for adding NaCl to adjust the concentration to 1-10 % and neutralizing precipitates; and a step for freeze-drying to obtain a pepsin soluble collagen (PC).

Abstract translation: 目的：提供从大眼金枪鱼皮肤分离的胶原蛋白的制造方法，以生产高质量的胶原蛋白，具有高溶解性和乳液稳定性。 构成：从大眼金枪鱼皮肤分离的胶原蛋白的制造方法，其特征在于，包括：在-30℃-100℃保存的大眼金枪鱼皮肤的洗涤步骤; 用0.05〜10.0％（w / v）碱溶液处理皮肤的步骤; 用蒸馏水洗涤和中和的步骤; 向皮肤中加入0.05〜10.0N的酸，然后搅拌和提取; 使用离心机分离提取液和残渣的步骤; 和干燥以获得酸溶性胶原（AC）的步骤; 添加0.5〜5.0 N酸的步骤; 加入0.5〜10％胃蛋白酶，搅拌水解1〜60小时; 使用过滤器分离提取液和残渣的步骤; 添加NaCl以将浓度调节至1-10％并中和沉淀的步骤; 和冷冻干燥步骤以获得胃蛋白酶可溶性胶原（PC）。

公开(公告)号：KR1020170044274A

公开(公告)日：2017-04-25

申请号：KR1020150143746

申请日：2015-10-15

Applicant: 강릉원주대학교산학협력단 ,  에덴농산영농조합법인

Inventor： 조순영 ,  김광우 ,  이승주 ,  박형숙 ,  김도윤 ,  김소라

IPC: A23L27/40 ,  A23L29/00 ,  A23L19/20 ,  A23B7/10

Abstract: 본발명은나트륨이함량이낮은발효소금을제조하기위한제조방법및 이소금을이용한저 나트륨김치의제조방법에관한것으로, 상세하게는천일염에함유된쓴맛이나는간수성분및 중금속등을제거시키고미네랄함량을증가시킴으로써, 일반소금에비해정미성분이뛰어나고경쟁력있는가격으로풍부한천연조미료의맛을낼 수있는발효소금을첨가하여본 발명의공정으로제조한김치가일반김치보다나트륨함량이낮고유산균이함량이풍부한김치를제조할수 있다.

Abstract translation: 本发明涉及一种用于低泡菜钠的制备方法，特别是涉及去除这种苦味盐卤成分和包含在太阳能盐，并通过使用制造方法和异金用于生产矿物的低发酵钠盐含量的重金属 通过增加量，与由添加发酵盐的方法，该方法可以是在竞争性的价格发明泡菜低的钠含量比常规泡菜乳酸含量丰富的天然调味料的味道制备的正盐口感极佳化合物相比 这种丰富的泡菜可以生产。

公开(公告)号：KR1020100023395A

公开(公告)日：2010-03-04

申请号：KR1020080082126

申请日：2008-08-22

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P9/10

Abstract: PURPOSE: A composition containing salmon fraction-dried powder or extract thereof is provided to suppress total cholesterol content and to prevent and treat arteriosclerosis. CONSTITUTION: A pharmaceutical composition for preventing and treating arteriosclerosis contains 0.1-50 weight% of salmon fraction-dried powder or extract thereof as an active ingredient. The fraction is obtained by dividing salmon body, intestine, head, fin, bone, cartilage, muscle, eye or gill. A method for manufacturing the salmon fraction-dried powder comprise: a first step of washing salmon and removing salinity and foreign materials; a second step of cutting salmon to obtain fraction; and a third step of freeze-drying fraction and pulverizing.

Abstract translation: 目的：提供含有鲑鱼馏分干燥粉末或其提取物的组合物以抑制总胆固醇含量并预防和治疗动脉硬化。 构成：用于预防和治疗动脉硬化的药物组合物含有0.1-50重量％的鲑鱼馏分干燥粉末或其提取物作为活性成分。 该分数通过分割鲑鱼体，肠，头，鳍，骨，软骨，肌肉，眼睛或鳃获得。 制造鲑鱼馏分干燥粉末的方法包括：洗涤鲑鱼并除去盐度和异物的第一步骤; 切割三文鱼以获得分数的第二步; 和冷冻干燥级分并粉碎的第三步骤。

公开(公告)号：KR1020100023394A

公开(公告)日：2010-03-04

申请号：KR1020080082125

申请日：2008-08-22

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing salmon fraction-dried powder or extract thereof is provided to suppress the content of neutral fat in blood and to prevent and treat hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains 0.1-50 weight% of salmon fraction-dried powder or extract thereof as an active ingredient. The salmon fraction is divided to whole salmon body, intestine, head, bone, cartilage, gill and muscle. The daily dosage of active ingredient is 0.0001-100 mg/kg. A functional health food for preventing and treating hyperlipidemia contains the salmon fraction-dried powder or extract thereof as an active ingredient. The food is used in the form of beverage, tablet, capsule, pill or liquor.

Abstract translation: 目的：提供含有三文鱼馏分干燥粉末或其提取物的组合物以抑制血液中的中性脂肪含量，并预防和治疗高脂血症。 构成：用于预防和治疗高脂血症的药物组合物含有0.1-50重量％的鲑鱼馏分干燥粉末或其提取物作为活性成分。 鲑鱼分为整个鲑鱼体，肠，头，骨，软骨，鳃和肌肉。 活性成分的日剂量为0.0001〜100mg / kg。 用于预防和治疗高脂血症的功能性保健食品含有作为活性成分的鲑鱼馏分干燥粉末或其提取物。 食物以饮料，片剂，胶囊，药丸或酒的形式使用。

公开(公告)号：KR1020100006894A

公开(公告)日：2010-01-22

申请号：KR1020080067215

申请日：2008-07-10

Applicant: 강릉원주대학교산학협력단

Inventor： 허길원 ,  김광우 ,  진현정 ,  최종원 ,  최용석 ,  어명희 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61P3/06

Abstract: PURPOSE: A composition containing pacific saury-fraction dried powder or its extract is provided to reduce total cholesterol content in blood and blood triglycerides. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidemia contains pacific saury-fraction dried powder or its extract as an active ingredient. A pacific saury fraction is obtained from total body of the pacific saury, head, bone, fin, skin, cartilage, eye, and gill. A functional health food for preventing and treating hyperlipidemia contains pacific saury-fraction dried powder or its extract as an active ingredient. The health food is used in the form of tablet, capsule, pill or liquid.

Abstract translation: 目的：提供含有太平刀柄级干粉或其提取物的组合物，以降低血液和血液中甘油三酯的总胆固醇含量。 构成：用于预防和治疗高脂血症的药物组合物含有作为活性成分的太平洋刀片级干粉或其提取物。 太平洋刀鱼部分是从太平洋刀刀，头，骨，鳍，皮肤，软骨，眼睛和鳃的全身中获得的。 用于预防和治疗高脂血症的功能性保健食品含有太平洋刀状干粉或其提取物作为活性成分。 保健食品以片剂，胶囊，丸剂或液体的形式使用。

公开(公告)号：KR1020090090943A

公开(公告)日：2009-08-26

申请号：KR1020080016519

申请日：2008-02-22

Applicant: 강릉원주대학교산학협력단

Inventor： 김광우 ,  김가현 ,  어명희 ,  김옥선 ,  조순영

IPC: A23K1/10 ,  A23K1/18 ,  A23K1/00

CPC classification number: A23K10/22 ,  A23K20/174 ,  A23K20/30 ,  A23K50/80

Abstract: A manufacturing method of a feed fish using protein source as a substitute for fish meal separated from liquid waste from mackerel processing is provided to add the water-soluble protein collected from the mackerel edge processing waste water. A manufacturing method of a fish farm fodder comprises next steps. The hydrochloric acid solution of about 0.01-10N is added to the mackerels processing waste water. The pH of the processing waste water is controlled as the fixed value between about 4-7 and centrifuges about 1-100 degrees and the mackerels extracts is collected. The collected mackerels extract the fish meal, wheat flour, vitamin mixture, mineral mixture, salt, yeast and fish tallow. The mixture is molded by a pelletizer, dries with the cold air drying during 1-10 days and pulverizes to the proper size. The feed for fish farming is comprised of 2-30wt% mackerels extracts, 20-40wt% fish meal, 18-75wt% wheat flour, 0.3-2wt% vitamin mixture, 0.3-2wt% mineral mixture, 0.3-2wt% salt, 0.1-1wt% yeast and 2-5wt% fish tallow.

Abstract translation: 提供使用蛋白质源作为从鲭鱼加工液体废物中分离的鱼粉的替代物的饲料的制造方法，以加入从鲭鱼边缘处理废水中收集的水溶性蛋白质。 鱼饲料的制造方法包括以下步骤。 将约0.01-10N的盐酸溶液加入到鲭鱼加工废水中。 处理废水的pH值控制在约4-7之间的固定值，离心约1-100度，并收集鲭鱼提取物。 收集的鲭鱼提取鱼粉，小麦粉，维生素混合物，矿物混合物，盐，酵母和鱼脂。 混合物用造粒机成型，在1-10天内用冷空气干燥并干燥至适当的大小。 养鱼饲料由2-30重量％鲭鱼提取物，20-40重量％鱼粉，18-75重量％小麦粉，0.3-2重量％维生素混合物，0.3-2重量％矿物混合物，0.3-2重量％盐，0.1 -1wt％酵母和2-5wt％鱼油。

公开(公告)号：KR1020090089956A

公开(公告)日：2009-08-25

申请号：KR1020080015137

申请日：2008-02-20

Applicant: 강릉원주대학교산학협력단

Inventor： 이기세 ,  김광우 ,  김옥선 ,  조순영

IPC: A61K35/60 ,  A61K9/14

CPC classification number: A61K35/60 ,  A61K9/14

Abstract: A composition for preventing and treating diabetes is provided to reduce blood sugar and prevent adut diseases caused by diabetes using dried powder or extract of Halocynthia roretzi. A pharmaceutical composition for preventing and treating diabetes comprises dried powder or extract of Halocynthia roretzi as an active ingredient. The extract is obtained by using water containing purified water, low alcohol of 1-4 carbon atoms or their mixture solvent. The content of the powder or extract is 0.1-50 weight% based on the total weight of composition.

Abstract translation: 提供了用于预防和治疗糖尿病的组合物，以减少血糖，并使用干粉或卤虫的提取物预防糖尿病引起的疾病。 用于预防和治疗糖尿病的药物组合物包含作为活性成分的干燥粉末或作为Halocynthia roretzi的提取物。 提取物通过使用含有纯化水，1-4个碳原子的低级醇或其混合溶剂的水来获得。 基于组合物的总重量，粉末或提取物的含量为0.1-50重量％。

公开(公告)号：KR1020090089954A

公开(公告)日：2009-08-25

申请号：KR1020080015135

申请日：2008-02-20

Applicant: 강릉원주대학교산학협력단

Inventor： 이기세 ,  김광우 ,  김옥선 ,  조순영

IPC: A61K35/616 ,  A61K9/14 ,  A23L33/00

CPC classification number: A61K35/616 ,  A23L33/00 ,  A61K9/14

Abstract: A composition for preventing and treating diabetes is provided to reduce blood sugar and have anti-diabetes effect using a dried powder or extract of Stichpus japonicus. A pharmaceutical composition for preventing and treating diabetes comprises dried powder or extract of Stichpus japonicas as an active ingredient. The Stichpus japonicas is included in Phylum Echinodermata, Class Holothuroidea, Order Aspidochirotida, and Stichopus japonicus Selenka. The content of dried powder or extract of Stichpus japonicas is 0.1-50 weight% based on the total weight.

Abstract translation: 提供了用于预防和治疗糖尿病的组合物，以使用干燥的粉末或日本or or的提取物降低血糖并具有抗糖尿病作用。 用于预防和治疗糖尿病的药物组合物包括作为活性成分的干燥粉末或蓟马提取物。 蓟马日食被包括在棘皮动物门，全息大戟，订果天竺葵和日本j and。 干us us的提取物的含量为0.1-50重量％。