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公开(公告)号：KR101561964B1
公开(公告)日：2015-10-20
申请号：KR1020130139232
申请日：2013-11-15
Applicant: 한국과학기술연구원 , 포항공과대학교 산학협력단
IPC: C07D413/14 , A61K31/421 , A61P31/12
CPC classification number: C07D413/14
Abstract: 본발명은하기화학식 1로표시되는신규옥사졸리디논화합물, 이의약학적으로허용가능한염 또는수화물및 이의제조방법, 상기화합물을포함하는 C형간염의예방또는치료용약학조성물에관한것이다. [화학식 1]상기식에서, R, R및 X는명세서중에정의한바와같다.
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公开(公告)号：KR1020140014310A
公开(公告)日：2014-02-05
申请号：KR1020140006244
申请日：2014-01-17
Applicant: 한국과학기술연구원
CPC classification number: A47L15/486 , A47L15/4214 , A47L15/481
Abstract: The present invention relates to a dish washer which has a dehumidifying device, which includes: a washing tub which is formed to accommodate dishes inside and has a sump in the lower part; a circulation duct which is connected to the washing tub at both ends in order to circulate air inside the washing tub; a dehumidifying device which is installed in the flow path of the circulation duct in order to remove moisture included in air which passes through the circulation duct in a drying process; at least one opening which is formed in the circulation duct which is necessary for the operation of the dehumidifying device in the operation process of the dehumidifying device in order to make external air flow to the circulation duct; a flow path conversion means which is installed in the flow path which branches into the washing tub and the opening in the circulation duct in order to connect the circulation duct with the washing tub in the drying process and connect the circulation duct with the outside in the operation process; and a dish washer which includes a reciprocating actuator installed in the opposite side of the opening based on the dehumidifying device in the circulation duct and generating vibration in order to induce the reciprocating flow of air which enters the circulation duct through the opening in the operation process.
Abstract translation: 洗碗机技术领域本发明涉及一种具有除湿装置的洗碗机，其包括：洗涤桶，其形成为容纳餐具内部并且在下部具有贮槽; 循环管道，其两端连接到洗涤桶，以便使洗涤桶内的空气循环; 除湿装置，其安装在循环管道的流路中，以便在干燥过程中除去通过循环管道的空气中包含的水分; 形成在循环管道中的至少一个开口，该开口在除湿装置的操作过程中为了使除湿装置的操作需要，以使外部空气流到循环管道; 流路改换装置，其安装在流路中，分支到洗涤桶和循环管道中的开口，以便在干燥过程中将循环管道与洗涤桶连接，并将循环管道与外部连接 操作流程; 以及洗碗机，其包括安装在所述开口的相对侧的往复式致动器，所述往复式致动器基于所述循环管道中的除湿装置并产生振动，以便在所述操作过程中通过所述开口引起进入所述循环管道的空气的往复流动 。
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公开(公告)号：KR1020130065368A
公开(公告)日：2013-06-19
申请号：KR1020110132198
申请日：2011-12-09
Applicant: 한국과학기술연구원 , 포항공과대학교 산학협력단
IPC: C07D215/28 , A61K31/47 , A61K31/4704 , A61P35/00
Abstract: PURPOSE: An aminoquinolone compound, or pharmaceutically acceptable salt or hydrate thereof with excellent anti-proliferation with respect to hepatitis C virus(HCV) is provided to prevent or treat hepatitis, liver cirrhosis, or liver cancer activity. CONSTITUTION: An aminoquinolone compound is denoted by chemical formula 1. A pharmaceutical composition for preventing or treating hepatitis, liver cirrhosis, or liver cancer contains an aminoquinolone compound of chemical formula 2, or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. An antiviral composition contains the aminoquinolone compound of chemical formula 2, or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. Mammalian HCV-infected cells are treated using the antiviral composition.
Abstract translation: 目的：提供氨基喹诺酮化合物或其对丙型肝炎病毒（HCV）具有优异抗增殖作用的药学上可接受的盐或水合物，以预防或治疗肝炎，肝硬化或肝癌活动。 构成：氨基喹诺酮化合物由化学式1表示。用于预防或治疗肝炎，肝硬化或肝癌的药物组合物含有化学式2的氨基喹诺酮化合物或其药学上可接受的盐或水合物作为活性成分。 抗病毒组合物含有化学式2的氨基喹诺酮化合物或其药学上可接受的盐或水合物作为活性成分。 使用抗病毒组合物处理哺乳动物HCV感染的细胞。
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Patent Agency Ranking
公开(公告)号：KR1020160039870A
公开(公告)日：2016-04-12
申请号：KR1020140133134
申请日：2014-10-02
Applicant: 한국과학기술연구원
IPC: C07D473/18 , C07D401/06 , A61K31/52 , A61P35/00
CPC classification number: C07D473/18 , A61K31/52 , C07D401/06
Abstract: 본발명은암세포에대한우수한항증식효능을나타내는퓨린화합물, 이의약학적으로허용가능한염, 또는수화물과, 이의제조방법및 이를유효성분으로함유하는암 전이및 증식성질환의예방또는치료용의약조성물, 및암세포에대한항암조성물에관한것으로서, 상기본 발명에따른화합물, 이의약학적으로허용가능한염, 또는수화물은낮은세포독성을보이면서우수한암세포억제활성및 항증식효능을나타내므로, 암세포저해는물론이고나아가암 전이및 증식성질환의예방또는암 치료에유용하게사용될수 있다.
Abstract translation: 本发明涉及对癌细胞表现出优异的抗增殖作用的嘌呤化合物，其药学上可接受的盐或水合物，其制备方法，包含其作为预防或治疗癌症转移和增殖性疾病的活性成分的药物组合物 ，以及对癌细胞有效的抗癌成分。 根据本发明，化合物及其药学上可接受的盐或水合物在显示出优异的癌细胞抑制活性和抗增殖作用的同时表现出低细胞毒性，因此可用于抑制癌细胞和预防或治疗癌症转移或增殖 疾病。 本发明的嘌呤化合物由化学式1表示。
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公开(公告)号：KR101375862B1
公开(公告)日：2014-03-17
申请号：KR1020140006244
申请日：2014-01-17
Applicant: 한국과학기술연구원
Abstract: 본 발명은 제습장치를 구비한 식기세척기에 관한 것으로서, 내부에 식기를 거치시키도록 형성되고 하부에 섬프가 설치되는 세척조, 상기 세척조 내부의 공기를 순환시키도록 양 단부가 상기 세척조와 연통되는 순환덕트, 건조과정에서 상기 순환덕트를 통과하는 공기에 포함된 수분을 흡착하여 제거하도록 상기 순환덕트의 유로에 구비되는 제습장치, 상기 제습장치의 재생과정에서 상기 제습장치의 재생에 필요한 외부의 공기를 상기 순환덕트로 출입시키도록 상기 순환덕트에 형성되는 적어도 하나의 개구, 상기 건조과정에서는 상기 순환덕트와 상기 세척조를 연통시키고 상기 재생과정에서는 상기 순환덕트와 외부를 연통시키도록 상기 순환덕트에서 상기 세척조와 상기 개구로 분기되는 유로에 설치되는 유로 전환수단, 및 상기 순환덕트에서 상기 제습장치를 기준으로 상기 개구의 반대편에 설치되고 상기 재생과정에서 상기 개구를 통해 상기 순환덕트로 출입하는 공기의 왕복유동을 유발하도록 진동을 발생시키는 왕복 액츄에이터를 포함하는 식기 세척기가 제공된다.
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公开(公告)号：KR1020130078956A
公开(公告)日：2013-07-10
申请号：KR1020120000141
申请日：2012-01-02
Applicant: 한국과학기술연구원
CPC classification number: A61N5/0622 , A61N2005/063 , A61N2005/0651 , Y10T29/49117
Abstract: PURPOSE: A probe-type light-emitting diode (LED) chip module for bio-stimulation and a manufacturing method thereof are provided to be produced in a small size by using an LED and stimulate a nerve without limiting biological activity, thereby providing an optical stimulator with excellent mobility and usability. CONSTITUTION: A probe-type LED chip module for bio-stimulation includes the following parts: an LED chip (10); a substrate (30) supporting the LED chip; an optical waveguide (50) collecting light emitted from the LED chip; and an insulation part (70) combining the substrate and the optical waveguide and insulating them from the outside. A manufacturing method of the probe-type LED chip module for bio-stimulation includes the following steps: a step of forming a cylindrical intermediate base material by extending an optical fiber base material which has a higher refractive index at the center than at the periphery; a step of forming an optical waveguide by extending the intermediate base material in a heated and unheated state; a step of combining the optical waveguide and the substrate where the LED chip is mounted; and a step of sealing the substrate and the optical waveguide with a light-absorbing insulator.
Abstract translation: 目的：提供用于生物刺激的探针型发光二极管（LED）芯片模块及其制造方法，其通过使用LED并且不限制生物活性而刺激神经而以小尺寸产生，从而提供光学 刺激器具有出色的移动性和可用性。 构成：用于生物刺激的探针型LED芯片模块包括以下部件：LED芯片（10）; 支撑所述LED芯片的基板（30） 收集从所述LED芯片发射的光的光波导（50）; 以及组合基板和光波导并将它们与外部绝缘的绝缘部分（70）。 用于生物刺激的探针型LED芯片模块的制造方法包括以下步骤：通过使在中心处的折射率高于周边的光纤基材延伸而形成圆筒状的中间基材的工序; 通过使中间基材在加热和未加热状态下延伸来形成光波导的步骤; 组合光波导和安装LED芯片的基板的步骤; 以及利用吸光绝缘体密封基板和光波导的步骤。
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公开(公告)号：KR1020130006554A
公开(公告)日：2013-01-17
申请号：KR1020110066569
申请日：2011-07-05
Applicant: 한국과학기술연구원
IPC: C07D413/10 , C07D413/14 , A61K31/422 , A61P31/04
CPC classification number: C07D413/10 , A61K31/422 , C07D413/14 , Y02A50/473 , Y02A50/481
Abstract: PURPOSE: AN oxazolidinone derivative containing a novel cyclic group is provided to ensure excellent antibacterial activity against gram-positive bacteria including various resistant strains. CONSTITUTION: An oxazolidionone derivative containing a cyclopenta[c]pyloriphenyl group is denoted by chemical formula 1. An antibacterial composition contains the oxazolidinone derivative or a pharmaceutically acceptable salt thereof as an active ingredient. The antibacterial composition has antibacterial activity against Staphylococcus sp., Enterococcus sp., E.coli, Bacillus sp., Salmonella sp. or Mycobacterium.
Abstract translation: 目的：提供含有新环状基团的恶唑烷酮衍生物，以确保对包括各种抗性菌株在内的革兰氏阳性菌具有优异的抗菌活性。 构成：含有环戊二烯并[c]苯乙烯基的恶唑烷酮衍生物由化学式1表示。抗菌组合物含有恶唑烷酮衍生物或其药学上可接受的盐作为活性成分。 抗菌组合物对葡萄球菌属，肠球菌属，肠杆菌属，大肠杆菌属，芽孢杆菌属，沙门氏菌属， 或分枝杆菌。
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公开(公告)号：KR1020120096842A
公开(公告)日：2012-08-31
申请号：KR1020110016203
申请日：2011-02-23
Applicant: 한국과학기술연구원
Inventor： 추현아 , 배애님 , 조용서 , 이효선 , 이지은 , 조경희 , 임혜원 , 서선희 , 송치만 , 정혜진 , 남길수 , 금교창 , 김동진 , 최경일 , 최기현 , 이재균 , 강용구 , 박웅서 , 이주현 , 신선미 , 아미드,압둘와히드 , 김영수 , 민선준
IPC: C07D413/12 , A61K31/496 , A61P25/00 , A61P9/00
CPC classification number: C07D413/12
Abstract: PURPOSE: A 5-(substituted alkylaminomethyl)isoxazole based compound as T-type calcium channel blocker is provided to have excellent activity as an antagonist of T- type calcium ion channel. CONSTITUTION: A 5-(substituted alkylaminomethyl)isoxazole based compound as T-type calcium channel blocker is represented by chemical formula 1. The encephalopathy therapy and for prevention agent selected from epilepsy, depression, Parkinson's disease, dementia, sleep disorder, an agent for cancer treatment and prevention, an agent for heart disease treatment and prevention selected from hypertensive, cardiac arrhythmia, angina, myocardial infarction, congestive heart failure, pharmaceutical composition for alleviating pain selected from neuropathic pain and chronic and acute pain includes a compound represented by chemical formula 1.
Abstract translation: 目的：提供作为T型钙通道阻滞剂的5-（取代的烷基氨基甲基）异恶唑基化合物作为T-型钙离子通道的拮抗剂具有优异的活性。 构成：以化学式1表示作为T型钙通道阻断剂的5-（取代烷基氨基甲基）异恶唑类化合物。脑病治疗和预防药物选自癫痫，抑郁症，帕金森病，痴呆，睡眠障碍， 癌症治疗和预防，选自高血压，心律失常，心绞痛，心肌梗塞，充血性心力衰竭，减轻选自神经性疼痛和慢性和急性疼痛的疼痛的药物组合物的心脏病治疗和预防剂，包括由化学式 1。
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