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公开(公告)号：KR1020140085819A
公开(公告)日：2014-07-08
申请号：KR1020120155509
申请日：2012-12-27
Applicant: 한국식품연구원
Abstract: The present invention provides an input part inputting genetic information by independently collecting the genetic information from test Database of Essential Gene (DEG) based genetic information, Mode of Action (MOA) analysis based genetic information, and literature based genetic information; a calculating part selecting common genetic information of the test DEG based genetic information, MOA analysis based genetic information, and literature based genetic information; a storage part storing the selected genetic information by dividing the genetic information into a first group relating to the common genetic information of the test DEG based genetic information, MOA analysis based genetic information, and literature based genetic information; a second group relating to common genetic information of the test DEG based genetic information and MOA analysis based genetic information; a third group relating to common genetic information of the MOA analysis based genetic information and the literature based genetic information; a fourth group relating to common genetic information of the test DEG based genetic information and the literature based genetic information; and a device to build obesity-related trophozoite genetic information, that compares and outputs a protein expression level and a gene expression level before and after trophozoite intake for the stored genetic information. Therefore, since gene relating to a targeted disease is proactively provided, a more efficient study on a gene purpose is conducted and nutrition dielectric information is provided.
Abstract translation: 本发明提供一种输入部分，通过从基因基因（DEG）的遗传信息，基于模式的遗传信息分析和基于文献的遗传信息的测试数据库独立收集遗传信息; 选择基于测试DEG的遗传信息，基于MOA分析的遗传信息和基于文献的遗传信息的常见遗传信息的计算部分; 通过将遗传信息划分为与基于测试DEG的遗传信息，基于MOA分析的遗传信息和基于文献的遗传信息的共同遗传信息相关的第一组中来存储所选择的遗传信息的存储部分; 关于基于测试DEG的遗传信息和基于MOA分析的遗传信息的常见遗传信息的第二组; 关于基于MOA分析的遗传信息和基于文献的遗传信息的常见遗传信息的第三组; 第四组涉及基于测试DEG的遗传信息和基于文献的遗传信息的常见遗传信息; 以及构建与肥胖相关的滋养体遗传信息的装置，其比较并输出保存的遗传信息中滋养体摄取前后的蛋白质表达水平和基因表达水平。 因此，由于主动提供与靶向疾病有关的基因，因此进行基因目的的更有效的研究，提供营养介电信息。
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公开(公告)号：KR101311736B1
公开(公告)日：2013-09-26
申请号：KR1020100121579
申请日：2010-12-01
Applicant: 한국식품연구원
IPC: G01N33/53 , G01N33/543 , G01N33/569
Abstract: 본 발명은 샌드위치 면역분석 바이오칩 및 이를 사용한 면역분석법으로서, 구체적으로 기능기로 표면이 개질된 고체-지지상의 기능기에 결합된 항체의 Fc 부위에 결합하는 제1단백질; 상기 제1단백질에 결합된 포획항체 및 기능기로 표면이 개질된 폴리스티렌 비드의 기능기에 결합된 항체의 Fc 부위에 결합하는 제2단백질; 상기 제2단백질에 결합된 검출항체를 포함하는 바이오칩 및 이를 사용한 면역분석법을 제공한다. 본 발명에 의하면, 병원성 미생물이 미량으로 존재하는 경우에도 정확하고 신속하게 병원성균을 검출할 수 있는 이점이 있다.
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23.发明授权
公开(公告)号：KR101235675B1
公开(公告)日：2013-02-21
申请号：KR1020100109058
申请日：2010-11-04
Applicant: 한국식품연구원
Abstract: 본 발명은 p-자일렌셀레노시아네이트를 유효성분으로 함유하는 비만 및 지질 관련 대사성 질환의 예방 및 치료용 약학적 조성물과 건강기능식품에 관한 것이다. 상기 조성물 또는 건강기능식품은 지방세포분화 저해 효능이 우수하다.
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公开(公告)号：KR1020130007909A
公开(公告)日：2013-01-21
申请号：KR1020110068563
申请日：2011-07-11
Applicant: 주식회사디엔에이링크 , 한국식품연구원
CPC classification number: C12Q1/6883 , C12Q2600/118
Abstract: PURPOSE: A polynucleotide for effectively diagnosing a risk of developing metabolic syndrome is provided to identify an individual with changed risk. CONSTITUTION: A composition for diagnosing a risk of developing metabolic syndrome contains a polynucleotide for diagnosing the risk of developing metabolic syndrome of an individual with obesity. A microarray for diagnosing the risk of developing metabolic syndrome contains the polynucleotide. A kit for diagnosing the risk of developing metabolic syndrome contains the polynucleotide. A method for identifying an individual with obesity, who has changed risk comprises: a step of providing a nucleic acid sample isolated from the individual with obesity; and a step of determining a nucleotide of a SNP site of one or more polynucleotides selected from sequence numbers 1-4.
Abstract translation: 目的：提供有效诊断发生代谢综合征风险的多核苷酸，以识别具有变化风险的个体。 构成：用于诊断发展代谢综合征风险的组合物含有用于诊断发生肥胖个体代谢综合征风险的多核苷酸。 用于诊断发生代谢综合征风险的微阵列包含多核苷酸。 用于诊断发展代谢综合征风险的试剂盒含有多核苷酸。 具有改变风险的用于鉴定具有肥胖症的个体的方法包括：提供从个体与肥胖分离的核酸样品的步骤; 以及确定选自序列号1-4中的一个或多个多核苷酸的SNP位点的核苷酸的步骤。
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公开(公告)号：KR101200671B1
公开(公告)日：2012-11-12
申请号：KR1020100077529
申请日：2010-08-11
Applicant: 한국식품연구원
IPC: A61K31/785 , A61K31/765 , A61K31/74 , A61P3/04
Abstract: 본 발명은 폴리감마글루탐산을 유효성분으로 함유하는 비만예방 및 치료용 조성물을 제공한다. 본 발명에 따른 비만예방 및 치료용 조성물은 약제학적 또는 식품조성물로서 지방세포의 분화를 억제하여 비만예방 및 치료에 탁월한 효과를 발휘한다.
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Patent Agency Ranking
公开(公告)号：KR1020120067821A
公开(公告)日：2012-06-26
申请号：KR1020100129432
申请日：2010-12-16
Applicant: 한국식품연구원
IPC: A61K31/09 , A61K31/343 , A61K36/79 , A61P3/10
Abstract: PURPOSE: A therapeutic agent containing complex lignan for treating type 2 diabetes is provided to suppress blood glucose and to reduce insulin resistance. CONSTITUTION: A therapeutic agent for treating type 2 diabetes contains complex lignin of 3-5 weight parts of schizandrin, 2-4 weight parts of gomisin A, and 0.5-1.5 weight parts of angeloylgomisin H. The schizandrin is schizandrin A, schizandrin B, schizandrin C, or mixture thereof. The complex lignin additionally contains schizandrol, angeloylgomisin O, angeloylgomisin P, epigomisin, pregomoisin, or deoxyschizandrin lignan. A health food for treating type 2 diabetes contains the complex lignan as an active ingredient. A method for reducing blood glucose comprises a step of administering the complex lignan to a subject by oral or intravenous injection, intranasal inhalation, or intramuscular or intraperitoneal administration.
Abstract translation: 目的：提供含有用于治疗2型糖尿病的复合木素素的治疗剂，以抑制血糖和降低胰岛素抵抗。 构成：用于治疗2型糖尿病的治疗剂含有3-5份重的分裂精神分裂素，2-4重量份的戈麦西斯A和0.5-1.5重量份的前叶葡萄糖素H的复合木质素。五味子素是五味子素A，五味子甙B， 五味子三素或其混合物。 复杂的木质素还含有五味子三醇，阴离子基葡萄糖苷O，阴离子基葡聚糖P，表不列生，前假丝酵母或脱氧星星木脂素。 用于治疗2型糖尿病的保健食品含有复合木素素作为活性成分。 减少血糖的方法包括通过口服或静脉内注射，鼻内吸入或肌肉内或腹膜内给药将复合木酚素施用于受试者的步骤。
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公开(公告)号：KR1020120061019A
公开(公告)日：2012-06-12
申请号：KR1020100109063
申请日：2010-11-04
Applicant: 한국식품연구원
IPC: A61K31/198 , A61P3/04 , A61P3/06 , A61P3/10
Abstract: PURPOSE: A pharmaceutical composition and health functional food containing selenomethionine are provided to prevent and treat obesity and lipid-related metabolic diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating obesity and lipid-related metabolic diseases contains selenomethionine as an active ingredient. The pharmaceutical composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, suppository, or sterilized injection solution. Selenomethionine suppresses differentiation of adipocyte. A health functional food contains selenomethionine as an active ingredient. The health functional food is used in the form of capsules, tablets, granules, powder, or beverage.
Abstract translation: 目的：提供含有硒代甲硫氨酸的药物组合物和保健功能食品，用于预防和治疗肥胖症和与脂质有关的代谢疾病。 构成：用于预防和治疗肥胖症和与脂质有关的代谢疾病的药物组合物含有硒代甲硫氨酸作为活性成分。 药物组合物以粉末，颗粒，片剂，胶囊，悬浮液，乳剂，糖浆，栓剂或灭菌注射液的形式制备。 硒代甲硫氨酸抑制脂肪细胞的分化。 健康功能食品含有硒代甲硫氨酸作为活性成分。 保健功能食品以胶囊，片剂，颗粒，粉末或饮料的形式使用。
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公开(公告)号：KR1020120057690A
公开(公告)日：2012-06-07
申请号：KR1020100077227
申请日：2010-08-11
Applicant: 호서대학교 산학협력단 , 한국식품연구원
CPC classification number: A61K36/48 , A23L11/09 , A23V2200/328 , A61K2236/331 , Y10S514/866
Abstract: PURPOSE: A health functional food for anti-diabetes and diabetes treatment containing meju extract is provided to lower blood glucose in vivo and to treat and relieve type 2 diabetes without side effect. CONSTITUTION: An anti-diabetes agent contains meju extract as active ingredient. The extract includes water extract or C1-C4 low carbon number alcohol extract. A health function al food for treating acne contains the meju extract as an active ingredient. The extract is water.
Abstract translation: 目的：提供含有菊苣提取物的抗糖尿病和糖尿病治疗的保健功能食品，用于降低体内血糖，并治疗和缓解2型糖尿病，无副作用。 构成：抗糖尿病药含有菊苣提取物作为有效成分。 提取物包括水提取物或C1-C4低碳醇提取物。 用于治疗痤疮的健康功能食物含有作为活性成分的菊粉提取物。 提取物是水。
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公开(公告)号：KR101153332B1
公开(公告)日：2012-06-07
申请号：KR1020100057167
申请日：2010-06-16
Applicant: 한국식품연구원
Abstract: 본발명은이동통신단말기로부터셋탑박스에부착된 RFID 태그정보를수신받아해당셋탑박스에서제공하는방송정보와함께그 방송정보에관련된식품정보를이동통신단말기에제공할수 있도록한 정보제공시스템및 그의정보제공방법에관한것이다. 이를위하여본 발명은셋탑박스에부착된 RFID 태그를판독하는이동통신단말기와통신가능한정보제공시스템으로, 통신망을통해상기이동통신단말기로부터판독된 RFID 태그의태그정보를수신하는수신부; 상기태그정보에셋탑박스식별정보가존재하는지여부를판단하는판단부; 상기판단부의판단결과, 상기태그정보에셋탑박스식별정보가존재하는경우해당셋탑박스식별정보를외부의방송사에제공하고, 상기외부의방송사로부터해당셋탑박스에서제공되는방송의채널정보를수신하는방송사인터페이스부; 상기방송사인터페이스부를통해수신된채널정보를이용하여데이터베이스로부터식품정보및 방송정보를각각추출하는정보추출부; 및상기추출된식품정보및 방송정보를상기이동통신단말기에제공하는정보제공부를포함하는것을특징으로하는정보제공시스템을제공한다.
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30.发明公开바이오케닌에이 또는 약리학적으로 허용되는 이의 염을 활성성분으로 함유하는 신생혈관생성과 관련된 질환의 치료용 조성물 无效用于治疗与包含生物素或其药学上接受的药物的血管生成相关的疾病的组合物
公开(公告)号：KR1020120029557A
公开(公告)日：2012-03-27
申请号：KR1020100091411
申请日：2010-09-17
Applicant: 한국식품연구원
IPC: A61K31/352 , A61K36/48 , A61P35/00 , A61P27/02
Abstract: PURPOSE: A composition containing biochanin A or pharmaceutically acceptable salt thereof for treating angiogenesis-associated diseases is provided to treat various diseases. CONSTITUTION: A composition for treating angiogenesis-associated diseases contains biochanin A or pharmaceutically acceptable salt thereof as an active ingredient. The angiogenesis-associated diseases are cancer, diabetetic retinopathy, rheumatic arthritis, psoriasis, inflammation, endometriosis, aging or hemandioma. A pharmaceutical composition for suppressing angiogenesis contains biochanin A or pharmaceutically acceptable salt thereof as an active ingredient.
Abstract translation: 目的：提供含有角鲨他汀A或其药学上可接受的盐用于治疗血管生成相关疾病的组合物以治疗各种疾病。 构成：用于治疗血管生成相关疾病的组合物含有作为活性成分的角鲨他汀A或其药学上可接受的盐。 血管生成相关疾病是癌症，糖尿病性视网膜病变，风湿性关节炎，牛皮癣，炎症，子宫内膜异位症，衰老或血管瘤。 用于抑制血管发生的药物组合物含有作为活性成分的角鲨他汀A或其药学上可接受的盐。
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