公开(公告)号：AT17845T

公开(公告)日：1986-02-15

申请号：AT82108292

申请日：1982-09-09

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  MUELLER JOSEF DR ,  LIETZ HELMUT ,  WIERSDORFF WALTER-WIELANT DR ,  HEGE HANS-GUENTHER DR ,  MUELLER CLAUS D DR ,  GRIES JOSEF DR ,  LENKE DIETER DR ,  VON PHILIPSBORN GERDA DR ,  RASCHACK MANFRED DR

IPC: A61K31/13 ,  A61K31/445 ,  C07D211/46 ,  C07D211/52 ,  C07D295/08 ,  C07C93/06 ,  C07C93/14 ,  C07C149/24

公开(公告)号：DE3361077D1

公开(公告)日：1985-11-28

申请号：DE3361077

申请日：1983-11-14

Applicant: BASF AG

Inventor： KUBINYI HUGO DR ,  TRAUT MARTIN DR ,  GRIES JOSEF DR

IPC: A61K31/455 ,  A61K31/185 ,  A61K38/00 ,  A61P9/12 ,  A61P25/04 ,  C07C67/00 ,  C07C325/00 ,  C07C327/20 ,  C07C327/32 ,  C07D205/04 ,  C07D207/16 ,  C07D209/20 ,  C07D209/26 ,  C07D211/60 ,  C07D217/26 ,  C07D277/06 ,  C07D333/24 ,  C07K5/062 ,  C07K5/065 ,  C07K5/078 ,  C07C153/07

公开(公告)号：DE3343671A1

公开(公告)日：1985-06-20

申请号：DE3343671

申请日：1983-12-02

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  SPIEGLER WOLFGANG DR ,  SIEGEL HARDO DR ,  MUELLER CLAUS D ,  PHILIPSBORN GERDA VON DR ,  LENKE DIETER DR ,  GRIES JOSEF DR

IPC: A61K31/34 ,  A61K31/341 ,  A61K31/38 ,  A61K31/381 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/495 ,  A61P9/06 ,  C07D207/32 ,  C07D207/333 ,  C07D213/50 ,  C07D231/12 ,  C07D307/46 ,  C07D333/22 ,  C07D409/12 ,  C07D213/30 ,  C07D401/10 ,  C07D401/12 ,  C07D403/10 ,  C07D403/12 ,  C07D413/10 ,  C07D413/12

公开(公告)号：DE3169653D1

公开(公告)日：1985-05-09

申请号：DE3169653

申请日：1981-06-03

Applicant: BASF AG

Inventor： THYES MARCO DR ,  KOENIG HORST DR ,  LENKE DIETER DR ,  LEHMANN HANS DIETER DR ,  GRIES JOSEF DR

IPC: A61K31/50 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04

Abstract: Novel 6-(p-acylaminophenyl)-4,5-dihydro-3(2H)-pyridazinones, whose acyl radical is derived from a cycloalkylcarboxylic acid, processes for their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in thrombo-embolic disorders and as anti-hypertensives.

公开(公告)号：DE3167816D1

公开(公告)日：1985-01-31

申请号：DE3167816

申请日：1981-06-29

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  WEIFENBACH HARALD DR ,  HOFMANN HANS PETER DR ,  KREISKOTT HORST DR

IPC: C07D295/08 ,  A61K31/495 ,  A61P9/12 ,  A61P25/20 ,  C07C45/70 ,  C07D295/092 ,  C07D303/22

公开(公告)号：GR75531B

公开(公告)日：1984-07-26

申请号：GR820167618

申请日：1982-03-17

Applicant: BASF AG

Inventor： EHRMANN ODKAR DR ,  RASCHACK MANFRED DR ,  GRIES JOSEF DR ,  KRETZSCHMAR ROLF DR ,  LEHMANN HANS DIETER DR ,  FRIEDRICH LUDWIC DR ,  WUPPERMANN DIRK DR ,  ZIMMERMANN FRANK DR ,  SEITZ WERNER DR ,  TREIBER HANS JOERG DR ,  DENGEL FERDINAUD DR ,  FRANK WOLFRAM DR

IPC: C07C255/42 ,  A61K31/275 ,  A61K31/277 ,  A61K31/335 ,  A61P9/06 ,  A61P9/10 ,  A61P37/08 ,  C07C253/30 ,  C07C255/32 ,  C07C255/53 ,  C07C255/58 ,  C07D317/06 ,  C07D317/58 ,  C07D317/60 ,  C07D319/02 ,  C07D319/08 ,  C07D319/18

公开(公告)号：DE3235370A1

公开(公告)日：1984-04-26

申请号：DE3235370

申请日：1982-09-24

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST PROF DR ,  GRIES JOSEF DR ,  LEHMANN HANS-DIETER PROF DR

IPC: C07D237/26 ,  A61K31/50

Abstract: Compounds of the formula in which R and X have the meaning given in the description, and their preparation are described. The novel substances are suitable for controlling diseases.

公开(公告)号：DE3213509A1

公开(公告)日：1983-10-20

申请号：DE3213509

申请日：1982-04-10

Applicant: BASF AG

Inventor： OSTERSEHLT BERND DIPL CHEM DR ,  FRANKE ALBRECHT DIPL CHEM DR ,  FRICKEL FRITZ FRIEDER DIPL CHE ,  THYES MARCO DIPL CHEM DR ,  FRIEDRICH LUDWIG DR ,  GRIES JOSEF DR ,  LENKE DIETER DR PROF

IPC: C07D405/12 ,  A61K31/415 ,  A61P1/04 ,  A61P43/00 ,  C07D233/61 ,  C07D521/00

公开(公告)号：DE2961653D1

公开(公告)日：1982-02-18

申请号：DE2961653

申请日：1979-04-11

Applicant: BASF AG

Inventor： THIEME PETER C DR ,  FRICKEL FRITZ-FRIEDER DR ,  THEOBALD HANS DR ,  FRANKE ALBRECHT DR ,  LENKE DIETER DR ,  GRIES JOSEF DR

IPC: A61K31/41 ,  A61K31/42 ,  A61P9/00 ,  A61P9/06 ,  A61P9/12 ,  A61P25/02 ,  C07D261/08

Abstract: Alkylamino-propanol derivatives of 3-alkyl-5-(2-hydroxystyryl)-isoxazole, of the general formula where R is hydrogen, alkyl of 1 to 8 carbon atoms, which is unsubstituted or substituted by hydroxyl, alkoxy of 1 to 3 carbon atoms or cycloalkyl with 3 to 8 carbon atoms in the ring, alkenyl or alkynyl of 2 to 8 carbon atoms, or cycloalkyl with 3 to 8 carbon atoms in the ring, the cycloalkyl rings being unsubstituted or mono- or di-substituted by alkyl of 1 to 3 carbon atoms, and R' is alkyl of 1 to 4 carbon atoms, and their addition salts with physiologically acceptable acids, their preparation, and pharmaceutical formulations which contain these compounds and which can be used as valuable drugs in the treatment of hypertonia, coronary diseases of the heart and cardiac arrhythmias.

公开(公告)号：AT39694T

公开(公告)日：1989-01-15

申请号：AT85108319

申请日：1985-07-05

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  SCHMIED BERNHARD DR ,  RASCHACK MANFRED DR ,  LEHMANN HANS-DIETER PROF DR ,  GRIES JOSEF DR ,  RUEBSAMEN KLAUS DR

IPC: A61K31/50 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D237/00 ,  C07D403/04 ,  C07D403/10