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公开(公告)号：CA2368625C
公开(公告)日：2008-11-18
申请号：CA2368625
申请日：2000-03-17
Applicant: BASF AG
Inventor： SACK HEINRICH , RUCHATZ FOLKER , SANNER AXEL , BREITENBACH JORG , BERNDL GUNTHER
Abstract: The invention relates to additives in powder form for use in solid pharmaceutical presentation forms. Said aids contain a pharmaceutically acceptable polymer and a liquid or semi-solid surface-activ e substance with solubilizing action.
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公开(公告)号：CA2311308C
公开(公告)日：2008-01-22
申请号：CA2311308
申请日：1998-11-30
Applicant: BASF AG
Inventor： MEFFERT HELMUT , BERNDL GUNTHER , ERNST ANDREAS , SANNER AXEL , KOTHRADE STEPHAN
IPC: A61K9/20 , A61K47/32 , A23K20/10 , A23K40/10 , A23K40/20 , A23L27/00 , A23L33/10 , A61K9/16 , A61K9/22 , A61K31/277 , A61K31/421 , A61K47/30
Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture a nd during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is use d as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.
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公开(公告)号：DE50005515D1
公开(公告)日：2004-04-08
申请号：DE50005515
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.
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公开(公告)号：AT260647T
公开(公告)日：2004-03-15
申请号：AT00914147
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.
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公开(公告)号：AT235891T
公开(公告)日：2003-04-15
申请号：AT99966909
申请日：1999-11-30
Applicant: BASF AG
Inventor： BERNDL GUNTHER , KOTHRADE STEPHAN , KESSLER THOMAS , LANGE ARMIN , HOFMANN JUERGEN , REINHOLD ULRICH
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Patent Agency Ranking
公开(公告)号：ES2181320T3
公开(公告)日：2003-02-16
申请号：ES98965716
申请日：1998-11-30
Applicant: BASF AG
Inventor： KOTHRADE STEPHAN , MEFFERT HELMUT , BERNDL GUNTHER , ERNST ANDREAS , SANNER AXEL
IPC: A61K47/32 , A23K20/10 , A23K40/10 , A23K40/20 , A23L27/00 , A23L33/10 , A61K9/16 , A61K9/20 , A61K9/22 , A61K31/277 , A61K31/421
Abstract: Solid dosage forms are obtained by mixing at least one polymeric binder, at least one active ingredient, and, where appropriate, conventional additives to form a plastic mixture, and shaping, using as polymeric binder a copolymer of an N-vinyllactam and a copolymerizable monomer having a hydrophobic radical. Dosage forms which show slow release of the active ingredient are obtained in a simple and low-cost manner.
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公开(公告)号：AT228828T
公开(公告)日：2002-12-15
申请号：AT00916925
申请日：2000-03-10
Applicant: BASF AG
Inventor： BERNDL GUNTHER , REINHOLD ULRICH , SIMON DIRK , LEHMANN STEPHAN
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公开(公告)号：AU7963101A
公开(公告)日：2001-12-11
申请号：AU7963101
申请日：2001-05-29
Applicant: BASF AG
Inventor： BERNDL GUNTHER , BREITENBACH JORG , HEGER ROBERT , STADLER MICHAEL , WILKE PETER , ROSENBERG JORG
IPC: A61F13/53 , A23P1/02 , A23P1/08 , A61F13/49 , A61K9/107 , A61K9/16 , A61K47/00 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/34 , A61K47/38
Abstract: The present invention relates to self-emulsifying formulations based on an active ingredient component and a formulation base with a lipid component and with a binder component and to the use of this formulation as dosage form in the life science sector. The invention also describes a process for producing self-emulsifying formulations by mixing the formulation components to form a plastic mixture and, where appropriate, to manufacture the formulations as dosage form advantageously by use of melt extrusion. The formulations spontaneously form emulsions in water or aqueous media.
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公开(公告)号：DE19929361A1
公开(公告)日：2001-01-04
申请号：DE19929361
申请日：1999-06-25
Applicant: BASF AG
Inventor： BERNDL GUNTHER , ROSENBERG JOERG
IPC: A61K9/14 , A61K9/20 , A61K31/4422 , A61K9/26
Abstract: The invention relates to preparations in the form of solid solutions of pharmaceutical active ingredients in an auxiliary agent matrix. The auxiliary agent matrix contains a homopolymer or copolymer of N-vinyl pyrrolidone as the polymer constituent and a surface-active surface which is liquid at 20 DEG C or has a drop point of between 20 DEG C and 50 DEG C.
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公开(公告)号：DE19913606A1
公开(公告)日：2000-09-28
申请号：DE19913606
申请日：1999-03-25
Applicant: BASF AG
Inventor： BERNDL GUNTHER , BREITENBACH JOERG , RUCHATZ FOLKER , SANNER AXEL , SACK HEINRICH
Abstract: The invention relates to additives in powder form for use in solid pharmaceutical presentation forms. Said aids contain a pharmaceutically acceptable polymer and a liquid or semi-solid surface-active substance with solubilizing action.
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