-
41.发明专利
公开(公告)号：AU2016219571B2
公开(公告)日：2018-03-15
申请号：AU2016219571
申请日：2016-08-23
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN
IPC: A61K31/445
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1 -dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
-
42.发明专利
公开(公告)号：RS55940B1
公开(公告)日：2017-09-29
申请号：RSP20170454
申请日：2006-12-28
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN
IPC: C07D215/56 , A61K31/445
-
43.发明专利
公开(公告)号：LT1993360T
公开(公告)日：2017-06-12
申请号：LT06848237
申请日：2006-12-28
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN
IPC: C07D215/56 , A61K31/445
-
公开(公告)号：CA2733908C
公开(公告)日：2017-05-30
申请号：CA2733908
申请日：2009-08-13
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N- [2,4-Bis( 1, 1-dimethylethyl)-5 -hydroxyphenyl]- 1,4-dihydro-4-oxoquinoline-3-carboxamide, and a polymer, wherein Compound 1 is present in an amount of about 80% by weight of the solid dispersion.
-
45.发明专利
公开(公告)号：CA2635581C
公开(公告)日：2017-02-28
申请号：CA2635581
申请日：2006-12-28
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , CONNELLY PATRICK , KRAWIEC MARIUSZ , GONG YUCHUAN , ROWE WILLIAM , FENG YUSHI , TRUDEAU MARTIN
IPC: C07D215/56 , A61K31/47 , A61P11/00
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound I ), and pharmaceutical compositions thereof.
-
Patent Agency Ranking46.发明专利
公开(公告)号：AU2013201426B2
公开(公告)日：2016-06-02
申请号：AU2013201426
申请日：2013-03-12
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , CONNELLY PATRICK , KRAWIEC MARIUSZ , GONG YUCHUAN , TRUDEAU MARTIN , FENG YUSHI
IPC: A61K31/445
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1 ,1-dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
-
公开(公告)号：BRPI0916877A2
公开(公告)日：2016-02-10
申请号：BRPI0916877
申请日：2009-08-13
Applicant: VERTEX PHARMA
Inventor： GROSSI ALFREDO , YOUNG CHRISTOPHER , OVERHOFF KIRK , DINEHART KRIK , VERWIJS MARINUS JACOBUS , BOTFIELD MARTYN , HURTER PATRICIA , GROOTENHUIS PETER D J , ROWE WILLIAM
IPC: A61K47/32
-
公开(公告)号：NZ591535A
公开(公告)日：2012-12-21
申请号：NZ59153509
申请日：2009-08-13
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D
Abstract: Disclosed is a pharmaceutical composition comprising: a solid dispersion of substantially amorphous N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), hydroxypropylmethylcellulose acetate succinate and sodium lauryl sulfate, microcrystalline cellulose, lactose, sodium croscarmellose, SLS, colloidal silicon dioxide, magnesium stearate.
-
公开(公告)号：PL3345625T3
公开(公告)日：2021-06-14
申请号：PL17204189
申请日：2009-08-13
Applicant: VERTEX PHARMA
-
公开(公告)号：RS61408B1
公开(公告)日：2021-03-31
申请号：RSP20210129
申请日：2009-08-13
Applicant: VERTEX PHARMA
-
-
-
-
-
-
-
-
-
Search Results
86
records
(took 0.022 seconds)
