公开(公告)号：ZA9708692B

公开(公告)日：1999-03-29

申请号：ZA9708692

申请日：1997-09-29

Applicant: BASF AG

Inventor： NIESSNER MANFRED ,  NILZ CLAUDIA ,  HOESSEL PETER ,  KOTHRADE STEPHAN ,  SANNER AXEL

IPC: A61K8/00 ,  A61K8/36 ,  A61K8/42 ,  A61K8/49 ,  A61K8/72 ,  A61K8/81 ,  A61K8/898 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C08F226/02 ,  C08F226/06 ,  A61K

CPC classification number: A61Q5/00 ,  A61K8/817 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  Y10S514/944 ,  Y10S514/945

公开(公告)号：CA2265532A1

公开(公告)日：1998-03-19

申请号：CA2265532

申请日：1997-09-11

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K47/30

Abstract: The present invention relates to a process for producing solid dosage forms by mixing at least one polymer binder, possibly at least one active substance and possibly the usual additives, as well as products derived from this mixture, of which at least one component is added in liquid state.

公开(公告)号：CA2311308C

公开(公告)日：2008-01-22

申请号：CA2311308

申请日：1998-11-30

Applicant: BASF AG

Inventor： MEFFERT HELMUT ,  BERNDL GUNTHER ,  ERNST ANDREAS ,  SANNER AXEL ,  KOTHRADE STEPHAN

IPC: A61K9/20 ,  A61K47/32 ,  A23K20/10 ,  A23K40/10 ,  A23K40/20 ,  A23L27/00 ,  A23L33/10 ,  A61K9/16 ,  A61K9/22 ,  A61K31/277 ,  A61K31/421 ,  A61K47/30

Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture a nd during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is use d as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.

公开(公告)号：ES2229572T3

公开(公告)日：2005-04-16

申请号：ES99106684

申请日：1999-04-01

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  NEGELE ANTON ,  MEFFERT HELMUT ,  SANNER AXEL

IPC: A01N25/10 ,  A61K8/72 ,  A61K47/32 ,  A61K8/81 ,  C08L39/00 ,  C09K23/00 ,  C09K23/52 ,  B01F17/00

Abstract: LA PRESENTE INVENCION SE REFIERE MEDIOS QUE CONTENGAN POR LO MENOS UN COMPONENTE INSOLUBLE EN AGUA Y POR LO MENOS UN COPOLIMERIZADO A BASE DE A)5 A 99% EN PESO DE POR LO MENOS UNA AMIDA DE ACIDO NVINILCARBONICO DE LA FORMULA I REPRESENTANDO R SUP,1 Y R 2 INDEPENDIENTES ENTRE SI E HIDROGENO Y C 1 -C 6 -ALQUILO; B)1 A 95% EN PESO DE POR LO MENOS UN MONOMERO DE RESIDUO HIDROFOBO QUE SE PUEDE COPOLIMERIZAR CON AMIDAS DEL ACIDO VINILCARBONICO DE LA FORMULA I; Y EVENTUALMENTE C)0 A 94% EN PESO DE POR LO MENOS OTRO MONOMERO COPOLIMERIZABLE. SE REFIERE TAMBIEN AL EMPLEO DE ESTOS COPOLIMERIZADOS PARA FACILITAR LA DISOLUCION.

公开(公告)号：AT280635T

公开(公告)日：2004-11-15

申请号：AT99106684

申请日：1999-04-01

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  NEGELE ANTON ,  MEFFERT HELMUT ,  SANNER AXEL

IPC: A61K47/32 ,  A01N25/10 ,  A61K8/72 ,  A61K8/81 ,  C08L39/00 ,  C09K23/00 ,  C09K23/52 ,  B01F17/00

Abstract: A copolymer consisting of the following monomers is used as a solubilizing agent: (a) 5-99 wt.% of at least one N-vinyl carboxamide (I), (b) 1-95 wt.% of at least one monomer with a hydrophobic group, and (c) 0-94 wt.% of at least one other comonomer. A copolymer consisting of the following monomers is used as a solubilizing agent: (a) 5-99 wt.% of at least one N-vinyl carboxamide of formula (I), (b) 1-95 wt.% of at least one monomer with a hydrophobic group, and (c) 0-94 wt.% of at least one other comonomer. R , R = H or 1-6C alkyl. Independent claims are also included for the following: (1) a composition containing at least one water-insoluble ingredient and at least one copolymer as above; (2) use of the copolymer as a protective colloid, especially for stabilizing oil-in-water emulsions.

公开(公告)号：AT239452T

公开(公告)日：2003-05-15

申请号：AT97942022

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：AT235891T

公开(公告)日：2003-04-15

申请号：AT99966909

申请日：1999-11-30

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  KOTHRADE STEPHAN ,  KESSLER THOMAS ,  LANGE ARMIN ,  HOFMANN JUERGEN ,  REINHOLD ULRICH

IPC: A61J3/10 ,  A61K9/16 ,  A61K9/20 ,  B29C47/42

公开(公告)号：ES2181320T3

公开(公告)日：2003-02-16

申请号：ES98965716

申请日：1998-11-30

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  MEFFERT HELMUT ,  BERNDL GUNTHER ,  ERNST ANDREAS ,  SANNER AXEL

IPC: A61K47/32 ,  A23K20/10 ,  A23K40/10 ,  A23K40/20 ,  A23L27/00 ,  A23L33/10 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K31/277 ,  A61K31/421

Abstract: Solid dosage forms are obtained by mixing at least one polymeric binder, at least one active ingredient, and, where appropriate, conventional additives to form a plastic mixture, and shaping, using as polymeric binder a copolymer of an N-vinyllactam and a copolymerizable monomer having a hydrophobic radical. Dosage forms which show slow release of the active ingredient are obtained in a simple and low-cost manner.

公开(公告)号：PT795567E

公开(公告)日：2002-10-31

申请号：PT97104190

申请日：1997-03-12

Applicant: BASF AG

Inventor： AXEL SANNER DR ,  BLANKENBURG RAINER ,  KOTHRADE STEPHAN

IPC: A01N25/00 ,  A61K8/81 ,  A61K47/32 ,  A61Q5/06 ,  A61Q19/00 ,  C08F2/10 ,  C08F2/38 ,  C08F4/04 ,  C08F226/06 ,  A61K7/00

公开(公告)号：AU724653B2

公开(公告)日：2000-09-28

申请号：AU4706797

申请日：1997-09-29

Applicant: BASF AG

Inventor： NIESSNER MANFRED ,  NILZ CLAUDIA ,  HOSSEL PETER ,  KOTHRADE STEPHAN ,  SANNER AXEL

IPC: A61K8/00 ,  A61K8/36 ,  A61K8/42 ,  A61K8/49 ,  A61K8/72 ,  A61K8/81 ,  A61K8/898 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C08F226/02 ,  C08F226/06 ,  A61K7/06 ,  A61K7/48

Abstract: A cosmetic composition comprising water-soluble copolymer, which as characteristic structural elements comprisesa) vinylcarboxamide units of the general formula IwhereR1 and R2 independently of one another are H, alkyl, cycloalkyl, aryl or aralkyl, andb) units of the general formula IIwhereA is a chemical bond or an alkylene group,the radicals R3 independently of one another are H, alkyl, cycloalkyl, aryl or aralkyl, or together with the nitrogen atom to which they are bonded, form an unsubstituted, mono- or polysubstituted, five- to seven-membered, heterocyclic, aromatic or nonaromatic ring, which if appropriate contains one or two further heteroatoms, selected from among O, N and S, it being possible for the heterocyclic ring to be fused to a further five- or six-membered, aromatic or nonaromatic ring,R4 is H, alkyl or aralkyl.