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公开(公告)号：DE602005015231D1
公开(公告)日：2009-08-13
申请号：DE602005015231
申请日：2005-08-31
Applicant: VERTEX PHARMA
Inventor： WILSON DEAN M , TERMIN ANDREAS P , GONZALEZ JESUS E , FANNING LEV T , NEUBERT TIMOTHY D , KRENITSKY PAUL , JOSHI PRAMOD , HURLEY DENNIS J , SHETH URVI , BOGER JOSHUA S
IPC: C07D239/94 , A61K31/498 , A61P9/06 , A61P25/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14
Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：AT435214T
公开(公告)日：2009-07-15
申请号：AT05807734
申请日：2005-08-31
Applicant: VERTEX PHARMA
Inventor： WILSON DEAN , TERMIN ANDREAS , GONZALEZ JESUS , FANNING LEV , NEUBERT TIMOTHY , KRENITSKY PAUL , JOSHI PRAMOD , HURLEY DENNIS , SHETH URVI , BOGER JOSHUA
IPC: C07D239/94 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12
Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：NO20084758L
公开(公告)日：2009-01-09
申请号：NO20084758
申请日：2008-11-11
Applicant: VERTEX PHARMA
Inventor： KRENITSKY PAUL , JOSHI PRAMOD , TERMIN ANDREAS , WANG JIAN , GONZALEZ JESUS , WILSON DEAN
IPC: C07C311/46 , C07C323/62 , C07D207/327 , C07D213/14 , C07D213/56 , C07D213/65 , C07D213/68 , C07D213/82 , C07D231/12 , C07D233/36 , C07D233/64 , C07D233/70 , C07D285/08 , C07D295/096 , C07D295/155 , C07D317/68
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公开(公告)号：MX2007002582A
公开(公告)日：2008-01-14
申请号：MX2007002582
申请日：2005-08-31
Applicant: VERTEX PHARMA
Inventor： WILSON DEAN M , TERMIN ANDREAS P , NEUBERT TIMOTHY D , GONZALEZ JESUS E III , FANNING LEV T D , KRENITSKY PAUL , JOSHI PRAMOD , HURLEY DENNOS J , SHETH URVI , BOGER JOSHUA S
IPC: A61K31/00 , A61P9/06 , A61P25/00 , C07D239/94 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14
Abstract: La presente invencion se relaciona con compuestos utiles como inhibidores de canales de sodio activados por voltaje. La invencion tambien proporciona las composiciones farmaceuticamente aceptables que comprenden los compuestos de la invencion y los metodos para utilizar las composiciones en el tratamiento de diversos trastornos.
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公开(公告)号：AU2007238857A1
公开(公告)日：2007-10-25
申请号：AU2007238857
申请日：2007-04-11
Applicant: VERTEX PHARMA
Inventor： KRENITSKY PAUL , WILSON DEAN , WANG JIAN , TERMIN ANDREAS , GONZALEZ JESUS , JOSHI PRAMOD
IPC: C07C311/46 , A61K31/18 , A61P29/00 , C07C323/62 , C07D207/32 , C07D213/65 , C07D213/74 , C07D233/54 , C07D239/34 , C07D295/20 , C07D317/60
Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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Patent Agency Ranking
公开(公告)号：MA28909B1
公开(公告)日：2007-10-01
申请号：MA29735
申请日：2007-03-02
Applicant: VERTEX PHARMA
Inventor： WILSON DEAN M , TERMIN ANDREAS P , GONZALEZ JESUS E III , FANNING LEV T D , NEUBERT TIMOTHY D , KRENITSKY PAUL , JOSHI PRAMOD , HURLEY DENNIS J , SHETH URVI , BOGER JOSHUA S
IPC: C07D239/94 , A61K31/498 , A61P9/06
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公开(公告)号：CA2628650A1
公开(公告)日：2007-05-24
申请号：CA2628650
申请日：2006-11-13
Applicant: VERTEX PHARMA
Inventor： FANNING LEV T D , WILSON DEAN , KRENITSKY PAUL , JOSHI PRAMOD , TERMIN ANDREAS , SHETH URVI
IPC: C07D403/04 , A61K31/505 , A61P29/00
Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：AU2006315675A1
公开(公告)日：2007-05-24
申请号：AU2006315675
申请日：2006-11-13
Applicant: VERTEX PHARMA
Inventor： WILSON DEAN , JOSHI PRAMOD , KRENITSKY PAUL , FANNING LEV T D , TERMIN ANDREAS , SHETH URVI
IPC: C07D403/04 , A61K31/505 , A61P29/00
Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：CA2578739A1
公开(公告)日：2006-03-16
申请号：CA2578739
申请日：2005-08-31
Applicant: VERTEX PHARMA
Inventor： HURLEY DENNIS J , NEUBERT TIMOTHY D , JOSHI PRAMOD , KRENITSKY PAUL , SHETH URVI , FANNING LEV T D , TERMIN ANDREAS P , GONZALEZ JESUS E III , WILSON DEAN M , BOGER JOSHUA S
IPC: C07D239/94 , A61K31/498 , A61P9/06 , A61P25/00 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14
Abstract: The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：HUE056716T2
公开(公告)日：2022-03-28
申请号：HUE17792230
申请日：2017-09-29
Applicant: VERTEX PHARMA
Inventor： ALCACIO TIMOTHY , BAEK MINSON , GROOTENHUIS PETER , HADIDA RUAH SARA , HUGHES ROBERT , KESHAVARZ-SHOKRI ALI , MCAULEY-AOKI RACHEL , MCCARTNEY JASON , MILLER MARK , VAN GOOR FREDRICK , ZHANG BEILI , ANDERSON COREY , CLEVELAND THOMAS , FRIEMAN BRYAN , KHATUYA HARIPADA , JOSHI PRAMOD , KRENITSKY PAUL , MELILLO VITO , PIERRE FABRICE , TERMIN ANDREAS , UY JOHNNY , ZHOU JINGLAN , ABELA ALEXANDER , BUSCH BRETT , PARASELLI PRASUNA , SIESEL DAVID
IPC: C07D401/14 , A61P11/12 , C07D471/14 , C07D498/14
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