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公开(公告)号：WO2006042034A8
公开(公告)日：2007-09-07
申请号：PCT/US2005036024
申请日：2005-10-07
Applicant: ABBOTT LAB , ZHANG GEOFF G , BRADLEY MICHAEL F , BARNES DAVID M , HENRY RODGER
Inventor： ZHANG GEOFF G , BRADLEY MICHAEL F , BARNES DAVID M , HENRY RODGER
IPC: C07D401/14
CPC classification number: C07D401/14 , A61K31/4709 , A61K47/02 , A61K47/12 , C07C31/26
Abstract: A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.
Abstract translation: 公开了药物的结晶形式，其制备方法，含有它的组合物以及治疗疾病的方法以及使用其抑制不良生理事件。
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公开(公告)号：BRPI1014369A2
公开(公告)日：2016-04-05
申请号：BRPI1014369
申请日：2010-04-30
Applicant: ABBOTT LAB
Inventor： ZHOU DELIANG , ZHANG GEOFF , RAVN MATTHEW , CATRON NATHANIEL , BRACKEMYER PAUL , HENRY RODGER , BORCHARDT THOMAS , LOU XIAOCHUN
IPC: C07D295/155 , A61K31/496 , A61P35/00
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公开(公告)号：MX2007004111A
公开(公告)日：2007-06-14
申请号：MX2007004111
申请日：2005-10-07
Applicant: ABBOTT LAB
Inventor： BARNES DAVID M , ZHANG GEOFF G , BRADLEY MICHAEL F , HENRY RODGER
IPC: C07D401/14
Abstract: Se describen una forma cristalina de un farmaco, formas para hacerla, composiciones que la contienen y metodos para el tratamiento de enfermedades e inhibicion de eventos fisiologicos adversos utilizandola.
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公开(公告)号：CA2582954C
公开(公告)日：2014-07-29
申请号：CA2582954
申请日：2005-10-07
Applicant: ABBOTT LAB
Inventor： ZHANG GEOFF G , BRADLEY MICHAEL F , BARNES DAVID M , HENRY RODGER
IPC: C07D401/14
Abstract: A crystalline form of 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylic acid, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.
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公开(公告)号：CA2658896A1
公开(公告)日：2008-01-31
申请号：CA2658896
申请日：2007-07-24
Applicant: ABBOTT LAB
Inventor： VISWANATH SHEKHAR , BARTELT LARRY , ZHANG GEOFF , CHEN SHUANG , BORCHARDT THOMAS , LEANNA ROBERT , HENRY RODGER , DHAON MADHUP , RASMUSSEN MICHAEL
IPC: C07D498/18 , A61K31/395 , A61K31/4353 , A61P37/06
Abstract: A rapamycin analog composition includes a crystalline form of a rapamycin analog. The crystal can be a hydrate, dehydrate, solvate, or desolvate. The rapamycin analog can have a structure of Formula (I), which is optionally a prodrug, salt, derivative, or combination thereof: Formula (I)
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Patent Agency Ranking
公开(公告)号：BRPI0714945A2
公开(公告)日：2013-05-21
申请号：BRPI0714945
申请日：2007-07-24
Applicant: ABBOTT LAB
Inventor： VISWANATH SHEKHAR , BARTELT LARRY , LEANNA ROBERT , RASMUSSEN MICHAEL , DHAON MADHUP , HENRY RODGER , BORCHARDT THOMAS , CHEN SHUANG , ZHANG GEOFF
IPC: C07D498/18 , A61K31/395 , A61K31/4353 , A61P37/06
Abstract: A process for preparing a crystalline form of a rapamycin analog, which process comprises: combining the rapamycin analog with at least one organic medium to form a mixture that is saturated with the rapamycin analog; incubating the saturated mixture until the rapamycin analog crystallizes; and recovering the crystalline rapamycin analog from the organic medium.
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公开(公告)号：MX2011011511A
公开(公告)日：2011-11-18
申请号：MX2011011511
申请日：2010-04-30
Applicant: ABBOTT LAB
Inventor： BORCHARDT THOMAS , HENRY RODGER , ZHANG GEOFF , LOU XIAOCHUN , CATRON NATHANIEL , ZHOU DELIANG , BRACKEMYER PAUL , RAVN MATTHEW
IPC: A61K31/496 , C07D295/155 , A61P35/00
Abstract: Bis-HCI de ABT-263 y los polimorfos cristalinos del mismo son ingredientes farmacéuticos activos apropiados para composiciones farmacéuticas útiles en el tratamiento de una enfermedad caracterizada por sobre-expresión de una o más proteínas anti-apoptóticas de la familia de BcI-2, por ejemplo cáncer.
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公开(公告)号：CA2758740A1
公开(公告)日：2010-11-04
申请号：CA2758740
申请日：2010-04-30
Applicant: ABBOTT LAB
Inventor： BORCHARDT THOMAS , BRACKEMYER PAUL , CATRON NATHANIEL , HENRY RODGER , LOU XIAOCHUN , RAVN MATTHEW , ZHANG GEOFF , ZHOU DELIANG
IPC: C07D295/155 , A61K31/496 , A61P35/00
Abstract: ABT-263 bis-HCl and crystalline polymorphs thereof are suitable active pharmaceutical ingredients for pharmaceutical compositions useful in treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.
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公开(公告)号：ZA200900740B
公开(公告)日：2010-05-26
申请号：ZA200900740
申请日：2007-07-24
Applicant: ABBOTT LAB
Inventor： VISWANATH SHEKHAR , BARTELT LARRY , LEANNA ROBERT , RASMUSSEN MICHAEL , DHAON MADHUP , HENRY RODGER , BORCHARDT THOMAS , CHEN SHUANG , ZHANG GEOFF
IPC: A61K20100101 , A61P20100101 , C07D20100101
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公开(公告)号：SA2251B1
公开(公告)日：2009-08-02
申请号：SA06270303
申请日：2001-08-07
Applicant: ABBOTT LAB
Inventor： DIECKMAN DANIEL A , CHEMBURKAR SANJAY , LECHUGA BALLESTEROS DAVID , HENRY RODGER , PORTER WILLIAM , NIU YOUPENG , FORT JAMES J
IPC: C07D239/02 , A61K20060101 , A61K31/513 , A61P20060101 , A61P31/18 , A61P43/00 , C07D20060101 , C07D239/10
Abstract: الملخص : يصفالاختراعالراهنأشكالبلورية crystalline forms جديدةمنلوبينافيرlopinavir.
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