公开(公告)号：US07868296B2

公开(公告)日：2011-01-11

申请号：US12413666

申请日：2009-03-30

Applicant: Frank M. Haran ,  Reena Meijer-Drees ,  Sebastien Tixier

Inventor： Frank M. Haran ,  Reena Meijer-Drees ,  Sebastien Tixier

IPC: G01J5/02

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/027 ,  G01J3/0297 ,  G01J3/28 ,  G01J3/427 ,  G01N21/274 ,  G01N21/3554 ,  G01N21/3563 ,  G01N21/359 ,  G01N2021/3137 ,  G01N2021/3166 ,  G01N2021/3188 ,  G01N2201/1293

Abstract: A spectroscopic method and spectroscopy system therefrom for analyzing samples. A sample includes a first chemical component that has a characteristic first absorption peak is provided. The sample is irradiated in a measurement waveband proximate to the first absorption peak, and at a first and a second reference waveband where the first chemical component lacks characteristic absorption features. Reflected or transmitted detection data is obtained including a measured power proximate to the first absorption peak and first and second reference powers at the reference wavebands. A plurality of different waveband ratios are evaluated using pairs of detection data to generate a plurality of measured waveband ratio values. A parameter of the first chemical component is then determined by evaluating a multidimensional polynomial calibration equation that relates the parameter of the first chemical component to the plurality of different waveband ratios by substituting the measured waveband ratio values into the calibration relation.

Abstract translation: 用于分析样品的光谱法和光谱系统。 样品包括具有特征性第一吸收峰的第一化学成分。 在接近第一吸收峰的测量波段和第一和第二参考波段照射样品，其中第一化学成分缺少特征吸收特征。 获得的反射或发射的检测数据包括接近第一吸收峰的测量的功率和在参考波段处的第一和第二参考功率。 使用成对的检测数据来评估多个不同的波段比，以产生多个测量的波段比值。 然后通过将测量的波段比值代入校正关系来评估将第一化学成分的参数与多个不同的波段比率相关联的多维多项式校准方程来确定第一化学成分的参数。

公开(公告)号：US07864320B2

公开(公告)日：2011-01-04

申请号：US12203454

申请日：2008-09-03

Applicant: Paul S. Bonino ,  Lalit Keshav Mestha ,  Gary W. Skinner

Inventor： Paul S. Bonino ,  Lalit Keshav Mestha ,  Gary W. Skinner

IPC: G01J3/46

CPC classification number: G01J3/46 ,  G01J3/02 ,  G01J3/027 ,  G01J3/0286 ,  G01J3/463 ,  H04N1/6033

Abstract: A method for estimating color measurements of color samples includes printing a color sample based on input data, measuring a color of the printed color sample with an in-line spectral sensor at a first temperature, and estimating a color of the printed color sample which would be output by a reference spectral sensor at a second temperature. The estimation is based on a thermochromatic model which represents relationships between measured colors of printed color samples on the in-line spectral sensor at the first temperature and the reference spectral sensor at the second temperature. The reference spectral sensor is a different type of sensor from the in-line spectral sensor, so the color response of the two spectral sensors is different, even when the measurement conditions are identical. Consequently, a set of printed spot color samples generate different measured colors at the second temperature on the in-line spectral sensor from the reference spectral sensor. The exemplary method allows these differences, as well as measurement temperature differences to be accounted for in the estimation.

Abstract translation: 用于估计颜色样本的颜色测量的方法包括基于输入数据打印颜色样本，在第一温度下用在线光谱传感器测量所打印的颜色样本的颜色，以及估计打印的颜色样本的颜色， 在第二温度下由参考光谱传感器输出。 该估计基于热色模型，其表示在第一温度下的在线光谱传感器和在第二温度下的参考光谱传感器的印刷色样的测量颜色之间的关系。 参考光谱传感器是与在线光谱传感器不同类型的传感器，因此即使测量条件相同，两个光谱传感器的颜色响应也是不同的。 因此，一组印刷的专色样本在来自参考光谱传感器的在线光谱传感器的第二温度下产生不同的测量颜色。 该示例性方法允许在估计中考虑到这些差异以及测量温度差异。

公开(公告)号：US20100292581A1

公开(公告)日：2010-11-18

申请号：US12779926

申请日：2010-05-13

Applicant: Peter Guy Howard ,  Steve C. White

Inventor： Peter Guy Howard ,  Steve C. White

IPC: A61B6/00 ,  G01J3/28

CPC classification number: G01N21/276 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/26 ,  G01J3/28 ,  G01N21/359 ,  G01N21/4738

Abstract: A dynamically calibrating optical spectrometer and method for dynamically calibrating the optical spectrometer are provided. The optical spectrometer may include a band-pass device and a device that scans, such that a scan window can be widened, and the edges of the band-pass device can be used to calibrate out drifts in the system. The optical spectrometer may be for acquiring and analyzing a spectroscopic sample of an analyte from a sampling region of the tissue of a person. The optical spectrometer includes a tunable source of electromagnetic radiation, a probe for delivering the electromagnetic radiation to the tissue at the sampling region and obtaining a diffuse reflectance signal from the tissue at the sampling region, a spectroscopic detector for analyzing the diffuse reflectance signal for presence of the analyte, and a wavelength calibration detector for calibrating the tunable source of electromagnetic radiation to a desired wavelength.

Abstract translation: 提供动态校准光谱仪和动态校准光谱仪的方法。 光谱仪可以包括带通装置和扫描的装置，使得可以加宽扫描窗口，并且可以使用带通装置的边缘校准系统中的漂移。 光谱仪可以用于从人的组织的采样区获取和分析分析物的光谱样品。 光谱仪包括可调谐的电磁辐射源，用于将电磁辐射传送到采样区域的组织并从采样区域的组织获得漫反射信号的探测器，用于分析漫反射信号以用于存在的光谱检测器 的分析物，以及波长校准检测器，用于校准可调谐的电磁辐射源至期望的波长。

公开(公告)号：US20100272354A1

公开(公告)日：2010-10-28

申请号：US12830045

申请日：2010-07-02

Applicant: Gary N. Bodnar ,  Christopher H. Pearson ,  Donald J. Staufenberg ,  Joshua M. Broehl ,  Bryan M. Shova ,  Ronald J. Duke ,  Karl F. Seibert

Inventor： Gary N. Bodnar ,  Christopher H. Pearson ,  Donald J. Staufenberg ,  Joshua M. Broehl ,  Bryan M. Shova ,  Ronald J. Duke ,  Karl F. Seibert

IPC: G06K9/00 ,  H04N5/335

CPC classification number: G01J3/02 ,  G01J1/0233 ,  G01J3/0262 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/50 ,  G01J3/524 ,  H04N5/2351

Abstract: A method for providing an intensity or brightness measurement using a digital image-capturing device comprising: selecting a target area within a field of view of the image-capturing device, the target area containing pixels; determining the brightness of pixels in the target area; accumulating the brightness values of the pixels in the target area; and determining a pixel value representative of the pixels in the target area. A device for making color measurements comprising an image-capture device, a processor or logic device, and a memory location for accumulating color data, and the processor or logic device is programmed to perform color measurements by accumulating the data for pixels located in the target area in memory, and determining a representative color value.

Abstract translation: 一种用于使用数字图像捕获装置提供强度或亮度测量的方法，包括：选择所述图像捕获装置的视野内的目标区域，所述目标区域包含像素; 确定目标区域中像素的亮度; 累积目标区域中的像素的亮度值; 以及确定表示所述目标区域中的像素的像素值。 一种用于进行颜色测量的设备，包括图像捕获设备，处理器或逻辑设备以及用于累积颜色数据的存储器位置，并且处理器或逻辑设备被编程为通过对位于目标中的像素累积数据来执行颜色测量 存储器中的区域，并且确定代表性颜色值。

公开(公告)号：US07813891B2

公开(公告)日：2010-10-12

申请号：US12242117

申请日：2008-09-30

Applicant: Paul S. Bonino ,  Timothy J. Sulenski

Inventor： Paul S. Bonino ,  Timothy J. Sulenski

IPC: G01B11/27

CPC classification number: G01B11/27 ,  G01J3/02 ,  G01J3/027 ,  G01J3/51 ,  G01J3/513 ,  G01J3/524

Abstract: This application generally relates to methods and systems for detecting spectrophotometer misalignment. In particular, the application may characterize the noise of a spectral measurement relative to a reference substrate known to exhibit a generally linear (flat) spectral output over a known spectrum. From the spectral measurement, a linear regression may be performed on a portion of the spectral output to determine a best fit line and a correlation of determination (“R-squared value”) may be determined correlated the measured data to the best fit line. Finally, the R squared value may be compared to a predetermined threshold R squared value to determine if the sensor is misaligned beyond an acceptable amount. If so, an alert may be generated.

Abstract translation: 本申请一般涉及用于检测分光光度计未对准的方法和系统。 特别地，应用可以表征相对于已知在已知光谱上呈现大致线性（平坦）光谱输出的参考基板的光谱测量的噪声。 从光谱测量可以对光谱输出的一部分进行线性回归以确定最佳拟合线，并且确定相关性（“R平方值”）可以被确定为将测量数据与最佳拟合线相关联。 最后，可以将R平方值与预定的阈值R平方值进行比较，以确定传感器是否偏移超过可接受的量。 如果是这样，可能会产生警报。

公开(公告)号：US07812946B1

公开(公告)日：2010-10-12

申请号：US11926196

申请日：2007-10-29

Applicant: Dennis K. Killinger ,  Anna Sharikova ,  Vasanthi Sivaprakasam

Inventor： Dennis K. Killinger ,  Anna Sharikova ,  Vasanthi Sivaprakasam

IPC: G01J3/30

CPC classification number: G01J3/4406 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0297 ,  G01N21/6402 ,  G01N21/6408 ,  G01N33/1826 ,  G01N2021/6471 ,  G01N2021/6484 ,  Y02A20/206

Abstract: A method for detecting trace levels of dissolved organic compounds and leached plastic compounds in drinking water includes the steps of employing deep ultraviolet light-emitting diode induced fluorescence at sensitivity levels of several parts per trillion in real time so that a more compact and inexpensive excitation source, relative to a deep UV laser-induced fluorescence, for fluorescence detection of dissolved organic compounds in water is provided. The deep UV light-emitting diode is operated at an excitation near 265 nm and the laser induced fluorescence is detected at an emission near 450 nm to 500 nm for the dissolved organic compounds and near 310 nm for leached plastic compounds. Optical absorption filters and optical bandpass filters are employed to reduce out-of-band light emitting diode emissions and to eliminate second order optical interference signals for the detection of a fluorescence signal near 450 nm to near 500 nm. The system can measure water contained within a quartz optical cell, within bottled water containers, or in a flowing stream of water.

Abstract translation: 用于检测饮用水中溶解的有机化合物和浸出的塑料化合物的痕量水平的方法包括以下实施方式：实际使用深度紫外发光二极管诱导的荧光，灵敏度为几万亿分之几，使得更紧凑和便宜的激发源 ，相对于深紫外激光诱导的荧光，用于在水中溶解的有机化合物的荧光检测。 深紫外发光二极管在265nm附近的激发下操作，激光诱导的荧光在溶解的有机化合物附近的450nm到500nm的发射下被检测，而对于浸出的塑料化合物，激光诱导的荧光在310nm附近被检测到。 采用光吸收滤光器和光带通滤波器来减少带外发光二极管发射，并消除二阶光干涉信号，以检测450nm至500nm附近的荧光信号。 该系统可以测量石英光学电池内，瓶装水容器内或流动的水流中所含的水。

公开(公告)号：US07791722B2

公开(公告)日：2010-09-07

申请号：US12212016

申请日：2008-09-17

Applicant: Hiroyuki Minato

Inventor： Hiroyuki Minato

IPC: G01J3/28 ,  G01J3/18

CPC classification number: G01J3/28 ,  G01J3/02 ,  G01J3/027

Abstract: A spectrophotometer is provided capable of reducing the influence of the vibration as much as possible when a wavelength dispersion element is rotationally driven and capable of increasing the analysis accuracy. When a fluorescence signal is obtained from the fluorescence detector, the central control unit A/D converts the fluorescence signal at sampling intervals of T1 for vibration convergence determination, and provides the result data to the data processor (S1). At the timing of performing the vibration convergence determination (S2), the data processor performs a predetermined signal processing to the digital signals obtained (S3), and determines whether all the data that have been obtained within a given period of time from the latest data are equal to or smaller than a specified value (S4). If all the data are equal to or smaller than the specified value, it is determined that the diffraction grating's vibration is converged, and the vibration convergence determination operation is terminated. After that, the central control unit changes the A/D conversion sampling interval to the interval T2 for obtaining the analysis data, and performs a spectrofluorometric measurement.

Abstract translation: 提供一种分光光度计，其能够在波长分散元件旋转驱动时尽可能地减小振动的影响，并且能够提高分析精度。 当从荧光检测器获得荧光信号时，中央控制单元A / D以用于振动收敛确定的采样间隔T1转换荧光信号，并将结果数据提供给数据处理器（S1）。 在执行振动收敛判定（S2）的定时，数据处理器对获得的数字信号进行预定的信号处理（S3），并且确定在最近的数据中在给定时间段内获得的所有数据 等于或小于规定值（S4）。 如果所有数据均等于或小于指定值，则确定衍射光栅的振动被收敛，并且终止振动收敛确定操作。 之后，中央控制单元将A / D转换采样间隔改变为间隔T2以获得分析数据，并执行分光荧光测量。

公开(公告)号：US20100213376A1

公开(公告)日：2010-08-26

申请号：US12719904

申请日：2010-03-09

Applicant: Charles W. Gardner, JR. ,  Patrick Treado ,  Matthew Nelson ,  Robert Schweitzer

Inventor： Charles W. Gardner, JR. ,  Patrick Treado ,  Matthew Nelson ,  Robert Schweitzer

IPC: G01J5/02 ,  G01J1/58 ,  G01J3/45 ,  G01N21/64

CPC classification number: G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0256 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/44 ,  G01N21/31 ,  G01N21/6456 ,  G01N21/6486 ,  G01N21/65

Abstract: A method and a portable device for assessing the occurrence of an agent in a sample. A sample is illuminated with photons emanating from a portable device to produce photons reflected, emitted, or absorbed from a set of multiple points in the sample having a defined geometric relationship. The portable device is used to simultaneously illuminate the sample and analyze the photons reflected, emitted, or absorbed from the set of multiple points using spectroscopic methods, including infrared, fluorescence, and UV/visible. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof.

Abstract translation: 一种用于评估样品中的试剂的发生的方法和便携式装置。 用便携式设备发出的光子照射样品，以产生从具有确定的几何关系的样品中的一组多个点反射，发射或吸收的光子。 便携式设备用于同时照亮样品并使用包括红外，荧光和紫外/可见光在内的光谱方法分析从该组多个点反射，发射或吸收的光子。 所评估的试剂可以包括危险剂，化学试剂，生物制剂，微生物，细菌，原生动物，病毒及其组合。

公开(公告)号：US07777878B2

公开(公告)日：2010-08-17

申请号：US12002650

申请日：2007-12-18

Applicant: Martin M. Liphardt

Inventor： Martin M. Liphardt

IPC: G01J3/08 ,  G01J3/42 ,  G01J4/04 ,  G01N21/21

CPC classification number: G01J3/447 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0224 ,  G01J3/0229 ,  G01J3/027 ,  G01J3/2823 ,  G01J3/457 ,  G01N21/211 ,  G01N2021/213

Abstract: Application of digital light processor (DLP) systems in monochromator, spectrophotometer or the like systems to mediate selection of individual wavelengths, and/or to image elected regions of a sample in an imaging ellipsometer, imaging polarimeter, imaging reflectometer, imaging spectrophotometer, and/or to provide chopped beams.

Abstract translation: 数字光处理器（DLP）系统在单色仪，分光光度计或类似系统中的应用，以介导单个波长的选择，和/或在成像椭偏仪，成像偏振计，成像反射计，成像分光光度计和/ 或提供切碎的梁。

公开(公告)号：US20100201800A1

公开(公告)日：2010-08-12

申请号：US12702622

申请日：2010-02-09

Applicant: Yoko YAMAMOTO ,  Hiroyuki FUKUDA

Inventor： Yoko YAMAMOTO ,  Hiroyuki FUKUDA

IPC: H04N7/18

CPC classification number: G02B21/365 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/2823 ,  G01J3/36 ,  G01N21/255 ,  G01N2201/129 ,  G06T7/0012 ,  G06T7/42 ,  G06T2200/24 ,  G06T2207/10056 ,  G06T2207/20104 ,  G06T2207/20221 ,  G06T2207/30004

Abstract: A reproduction apparatus includes an attribute information recording unit that records image attribute information in which the attribute values indicating the attributes of each image are set; a target image selecting unit that selects a target image from images; a search condition setting unit that sets the search conditions that are the attribute values related to the target image in the image attribute information; a reproduction information creating unit that creates information for reproduction by setting image attribute information that satisfies the search conditions in the image attribute information; a search condition selecting unit that selects the search conditions as reproduction search conditions; and a search result reproducing unit that causes a display unit to display an image to be reproduced with respect to the image attribute information set in the information for reproduction when the reproduction search conditions are selected, and reproduces search results related to the target image.

Abstract translation: 再现装置包括：属性信息记录单元，记录图像属性信息，其中指定每个图像的属性的属性值被设置; 目标图像选择单元，其从图像中选择目标图像; 搜索条件设置单元，其将作为与所述目标图像相关的属性值的搜索条件设置在所述图像属性信息中; 再现信息生成单元，其通过将图像属性信息中满足搜索条件的图像属性信息设定，来生成用于再现的信息; 选择搜索条件作为再现搜索条件的搜索条件选择单元; 以及搜索结果再现单元，当选择再现搜索条件时，使得显示单元相对于在再现信息中设置的图像属性信息显示要再现的图像，并且再现与目标图像相关的搜索结果。