公开(公告)号：US20150107348A1

公开(公告)日：2015-04-23

申请号：US14506789

申请日：2014-10-06

Applicant: CANON KABUSHIKI KAISHA

Inventor： Eishi Igata

IPC: G01N19/04 ,  G01F1/00

CPC classification number: G01F1/00 ,  B01L3/502707 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/161 ,  B81B2201/051 ,  B81C99/0045 ,  G01N11/04 ,  G01N33/442

Abstract: A curing degree of a bonding layer is checked when a hollow microchannel is produced by bonding a plurality of plates through intermediation of the bonding layer. Provided is a method of inspecting a fluidic device including: one substrate and another substrate, at least one of the substrates having a minute groove formed therein; and a hollow channel formed by bonding the substrates to each other through intermediation of an adhesive layer having a contact angle that changes depending on a curing degree by irradiation of light. The method includes measuring a flow rate at which a solution flows through the channel with a capillary force when no liquid is present after the irradiation of light.

Abstract translation: 当通过粘合层的中间结合多个板来制造中空微通道时，检查粘合层的固化程度。 提供一种检查流体装置的方法，包括：一个基板和另一个基板，至少一个基板上形成有微小的凹槽; 以及通过借助于通过照射光而具有随着固化程度而变化的接触角的粘合剂层将基板彼此接合而形成的中空通道。 该方法包括在照射光线之后，当没有液体存在时，通过毛细管力测量溶液流过通道的流速。

公开(公告)号：US20150044110A1

公开(公告)日：2015-02-12

申请号：US14451805

申请日：2014-08-05

Applicant: STMicroelectronics S.r.l.

Inventor： Lorenzo Colombo ,  Marco Salina ,  Daria Doria

IPC: B01L3/00 ,  B32B37/18 ,  G03F7/20 ,  B05D3/06 ,  B32B38/00 ,  B32B37/24 ,  B05D1/00 ,  B05D3/10

CPC classification number: B01L3/5027 ,  B01J19/0093 ,  B01J2219/0084 ,  B01L3/5088 ,  B01L2200/12 ,  B01L2300/0819 ,  B01L2300/089 ,  B01L2300/0893 ,  B01L2300/12 ,  B01L2300/165 ,  B05D1/005 ,  B05D3/06 ,  B05D3/107 ,  B32B37/18 ,  B32B37/24 ,  B32B38/00 ,  B32B2037/243 ,  B32B2038/0076 ,  B32B2255/00 ,  B32B2307/728 ,  B32B2310/0806 ,  B81B2201/0214 ,  B81B2201/051 ,  B81C1/00206 ,  G03F7/20

Abstract: A microfluidic device includes a support body having a first surface and a second surface opposite to one another. The first surface is hydrophilic. A surface modification layer extends over the first surface of the support body. At least one opening is formed to extend through the surface modification layer and expose a portion of the first surface. The surface modification layer is hydrophobic. In particular, the surface modification layer is made of a photodefinible material chosen from among: an epoxy resin, a polyamide, and a photocurable siloxane-based polymer. The openings are functionalized using probe molecules designed to bind with specific target molecules to be detected.

Abstract translation: 微流体装置包括具有第一表面和彼此相对的第二表面的支撑体。 第一个表面是亲水的。 表面改性层在支撑体的第一表面上延伸。 形成至少一个开口以延伸穿过表面改性层并暴露第一表面的一部分。 表面改性层是疏水性的。 特别地，表面改性层由选自以下的光可固化材料制成：环氧树脂，聚酰胺和光固化性硅氧烷基聚合物。 使用设计成与要检测的特异性靶分子结合的探针分子来使开口功能化。

公开(公告)号：US08877345B2

公开(公告)日：2014-11-04

申请号：US12933448

申请日：2009-03-12

Applicant: Thomas Cornelius ,  Wolfgang Ensinger ,  Reinhard Neumann ,  Markus Rauber

Inventor： Thomas Cornelius ,  Wolfgang Ensinger ,  Reinhard Neumann ,  Markus Rauber

IPC: G01F1/688 ,  C25D1/04 ,  C25D1/08 ,  C25D1/00 ,  B01J23/42 ,  B82Y30/00 ,  B01J35/00 ,  B01J23/72 ,  B22F3/00 ,  B01J19/00 ,  B82Y15/00 ,  B81C99/00 ,  B22F1/00 ,  C25D5/18

CPC classification number: C25D1/006 ,  B01J19/0093 ,  B01J23/42 ,  B01J23/72 ,  B01J35/0006 ,  B01J2219/00783 ,  B01J2219/00835 ,  B01J2219/00846 ,  B01J2219/00853 ,  B01J2219/0086 ,  B01J2219/00873 ,  B22F1/0025 ,  B22F3/002 ,  B81B2201/0292 ,  B81B2201/051 ,  B81C99/0085 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C25D1/00 ,  C25D1/003 ,  C25D1/04 ,  C25D1/08 ,  C25D5/18 ,  G01F1/688 ,  G01N25/00 ,  Y10S977/762 ,  Y10T29/49117 ,  Y10T428/12201 ,  Y10T428/12389 ,  Y10T428/24562 ,  Y10T428/24893 ,  Y10T428/25

Abstract: The invention concerns the production of segmented nanowires and components having said segmented nanowires.For the production of the nanowire structural element, a template based process is used preferably, wherein the electrochemical deposition of the nanowires in nanopores is carried out. In this manner, numerous nanowires are created in the template foil.For the electrochemical deposition of the nanowires, a reversed pulse procedure with an alternating sequence consisting of cathodic deposition pulses and anodic counter-pulses is carried out. By this means, segmented nanowires can be produced.

Abstract translation: 本发明涉及具有所述分段纳米线的分段纳米线和组分的生产。 为了制造纳米线结构元件，优选使用基于模板的方法，其中进行纳米线中的纳米线的电化学沉积。 以这种方式，在模板箔中形成许多纳米线。 对于纳米线的电化学沉积，执行具有由阴极沉积脉冲和阳极反向脉冲组成的交替序列的反向脉冲程序。 通过这种方式，可以生产分段的纳米线。

公开(公告)号：US08771610B2

公开(公告)日：2014-07-08

申请号：US12904557

申请日：2010-10-14

Applicant: Kak Namkoong ,  Su-hyeon Kim ,  Jin-tae Kim ,  Chin-sung Park ,  Young-sun Lee

Inventor： Kak Namkoong ,  Su-hyeon Kim ,  Jin-tae Kim ,  Chin-sung Park ,  Young-sun Lee

IPC: B01L3/00

CPC classification number: B81B3/0081 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01L3/5027 ,  B01L7/5255 ,  B01L2200/14 ,  B01L2200/147 ,  B01L2300/1805 ,  B01L2300/1827 ,  B81B2201/051 ,  F28F21/02 ,  F28F2013/006

Abstract: A fluid reaction device includes a microfluidic reaction chip which accommodates a fluid, a heater, and a heat transfer facilitating layer which is interposed between the microfluidic reaction chip and the heater, the heat transfer facilitating layer has a higher thermal conductivity than air and can hold particles, wherein formation of an air layer can be prevented.

Abstract translation: 流体反应装置包括容纳流体的微流体反应芯片，加热器和介于微流体反应芯片和加热器之间的传热促进层，传热促进层具有比空气更高的导热性并且可以保持 颗粒，其中可以防止空气层的形成。

公开(公告)号：US08679423B2

公开(公告)日：2014-03-25

申请号：US12988213

申请日：2009-04-23

Applicant: Yves Fouillet

Inventor： Yves Fouillet

IPC: B03C9/00 ,  B01L3/00

CPC classification number: B82Y30/00 ,  B01L3/502707 ,  B01L3/50273 ,  B01L2200/12 ,  B01L2300/0887 ,  B01L2400/0415 ,  B81B2201/051 ,  B81C1/00071 ,  B81C2201/0149

Abstract: A microfluidic device, including a microfluidic network, including: a) two parallel plates each including one or more electrodes, b) at least one channel, arranged between the two plates, made from a material obtained by solidification or hardening of a material of a first fluid, and c) a mechanism varying a physical parameter of the material constituting walls of the channel so as to cause the material to pass at least from the liquid state to the solid state.

Abstract translation: 包括微流体网络的微流体装置，包括：a）两个平行板，每个平行板包括一个或多个电极，b）布置在两个板之间的至少一个通道，由通过固化或硬化材料获得的材料制成 第一流体，以及c）改变通道的材料构成壁的物理参数以使材料至少从液态通过至固态的机构。

公开(公告)号：US08377362B2

公开(公告)日：2013-02-19

申请号：US13059494

申请日：2009-08-17

Applicant: Kanji Sekihara ,  Takehiko Goshima

Inventor： Kanji Sekihara ,  Takehiko Goshima

IPC: B29C33/42 ,  B29C45/16

CPC classification number: B29C45/263 ,  B01L3/502707 ,  B01L2200/10 ,  B01L2200/12 ,  B01L2300/044 ,  B01L2300/12 ,  B29C45/0025 ,  B81B2201/051 ,  B81B2203/0338 ,  B81C1/0046

Abstract: A die (100) is provided with: a cavity which can contain a molten resin; a micro-structure (102) provided on a molding transfer surface (101) forming the cavity such that the fine structure protrudes to the cavity side from the molding transfer surface (101); and a anti-shrinkage convex section (103) protruding higher than the micro-structure (102) to the cavity side from one surface. A molten resin is applied to the die (100) and the surface of the die is relatively removed in the order of the micro-structure (102) and the anti-shrinkage convex section (103) from a resin substrate (001) formed by solidifying the resin.

Abstract translation: 模具（100）设置有：可容纳熔融树脂的空腔; 设置在形成所述空腔的成型转印表面（101）上的微结构（102），使得所述精细结构从所述模制转印表面（101）突出到所述空腔侧; 以及从一个表面向空腔侧突出高于微结构（102）的抗收缩凸部（103）。 将熔融树脂施加到模具（100），并且从微结构（102）和抗收缩凸部（103）的顺序相对于模具的表面相对于由 固化树脂。

公开(公告)号：US08369070B2

公开(公告)日：2013-02-05

申请号：US12686978

申请日：2010-01-13

Applicant: Henry Helvajian ,  William W. Hansen ,  Lee F. Steffeney

Inventor： Henry Helvajian ,  William W. Hansen ,  Lee F. Steffeney

IPC: H05K5/00

CPC classification number: H05K3/101 ,  B01J19/0093 ,  B01J2219/00824 ,  B01J2219/00835 ,  B01J2219/00853 ,  B01J2219/00941 ,  B01J2219/00948 ,  B01L3/502707 ,  B01L2300/12 ,  B81B2201/051 ,  B81B2203/0338 ,  B81C1/00634 ,  G02B2006/12035 ,  G02B2006/12171 ,  H01P3/121 ,  H05K1/0306 ,  H05K1/16 ,  H05K1/162 ,  H05K1/165 ,  H05K3/0023 ,  Y10T29/49117

Abstract: A photostructurable ceramic is processed using photostructuring process steps for embedding devices within a photostructurable ceramic volume, the devices may include one or more of chemical, mechanical, electrical, electromagnetic, optical, and acoustic devices, all made in part by creating device material within the ceramic or by disposing a device material through surface ports of the ceramic volume, with the devices being interconnected using internal connections and surface interfaces.

Abstract translation: 使用用于将装置嵌入可光可陶瓷陶瓷体积内的光学结构化工艺步骤来处理可光刻陶瓷，所述装置可以包括化学，机械，电气，电磁，光学和声学装置中的一种或多种，​​所有这些都部分地通过在 陶瓷或通过陶瓷体的表面端口设置器件材料，使用内部连接和表面接口互连这些器件。

公开(公告)号：US20120288422A1

公开(公告)日：2012-11-15

申请号：US13469377

申请日：2012-05-11

Applicant: Edvard KALVESTEN

Inventor： Edvard KALVESTEN

IPC: B81B1/00 ,  B32B3/20 ,  C03B23/24

CPC classification number: C03B23/24 ,  B81B2201/051 ,  B81B2203/0338 ,  B81C1/00119 ,  B81C2203/036 ,  Y10T428/24562

Abstract: A method of making a microfluidic device, includes: providing an optically transparent bottom substrate and an optically transparent top substrate, each made of glass. Recesses are made in the top substrate and the top and bottom substrates are bonded together. Then, material is removed from the top substrate to expose the recesses, and a lid is attached to the top substrate so as to cover the recesses whereby channels are formed. At least that surface of the lid facing towards the recesses in the top substrate has a surface roughness of

Abstract translation: 制造微流体装置的方法包括：提供每个由玻璃制成的光学透明的底部基底和光学透明的顶部基底。 在顶部基板上形成凹部，顶部和底部基板结合在一起。 然后，将材料从顶部基板移除以露出凹部，并且将盖子附接到顶部基板，以覆盖凹部，从而形成通道。 至少面向顶部衬底中的凹部的盖的表面具有<5nm，优选<2nm的表面粗糙度。 还描述了一种微流体装置，其包括光学透明材料的主体，以及在主体内延伸的至少一个通道，还具有底表面，顶表面和侧壁的通道。 顶表面和底表面均表现出粗糙度<5nm，优选<2nm。

公开(公告)号：US08156762B2

公开(公告)日：2012-04-17

申请号：US12072754

申请日：2008-02-28

Applicant: Thierry Luc Alain Dannoux ,  Paulo Gaspar Jorge Marques ,  Robert Michael Morena ,  Cameron Wayne Tanner

Inventor： Thierry Luc Alain Dannoux ,  Paulo Gaspar Jorge Marques ,  Robert Michael Morena ,  Cameron Wayne Tanner

IPC: C03B23/02 ,  C03B23/26

CPC classification number: C03B23/203 ,  B81B2201/051 ,  B81C99/0085 ,  B81C2201/019 ,  B81C2201/036 ,  C03B2215/412

Abstract: Described herein are methods for making microfluidic devices comprising glass or glass-containing materials, wherein the methods have decreased cost and/or improved dimensional properties over similar formed glass articles produced using current techniques.

Abstract translation: 本文描述了用于制造包含玻璃或含玻璃材料的微流体装置的方法，其中相对于使用当前技术制备的相似的成形玻璃制品，所述方法具有降低的成本和/或改善的尺寸性能。

公开(公告)号：US20120009097A1

公开(公告)日：2012-01-12

申请号：US13238128

申请日：2011-09-21

Applicant: Takeki YAMAMOTO ,  Masaya Nakatani ,  Makoto Takahashi ,  Takami Ishida

Inventor： Takeki YAMAMOTO ,  Masaya Nakatani ,  Makoto Takahashi ,  Takami Ishida

IPC: B01L99/00

CPC classification number: B01L3/502746 ,  B01J2219/00286 ,  B01J2219/00509 ,  B01J2219/00511 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01L3/502707 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2400/086 ,  B81B1/008 ,  B81B2201/051 ,  B81B2203/0338 ,  B81B2203/0361 ,  B81B2203/0392 ,  B81C1/00206

Abstract: A flow path device includes a substrate having a trench and columns extending from a bottom of the trench. The trench is configured to have a fluid flowing therein. Each of columns has a side surface having grooves formed therein. The grooves have an annular shape or an arcuate shape. This flow path device reduces damage to the columns, and has a high reliability.

Abstract translation: 流路装置包括具有从沟槽的底部延伸的沟槽和列的衬底。 沟槽被构造成具有在其中流动的流体。 每列具有形成在其中的槽的侧表面。 凹槽具有环形或弓形。 该流路装置减少对柱的损伤，并且具有高可靠性。